Mir216b (microRNA 216b) - Rat Genome Database

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Gene: Mir216b (microRNA 216b) Rattus norvegicus
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Symbol: Mir216b
Name: microRNA 216b
RGD ID: 4888592
Description: Predicted to be involved in gene expression and mesonephric duct formation. Predicted to act upstream of or within cellular response to amino acid stimulus and cellular response to leukemia inhibitory factor. Orthologous to human MIR216B (microRNA 216b); INTERACTS WITH ceruletide; nitrofen; zinc atom.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-216b; rno-mir-216b
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,714,026 - 106,714,127 (+)NCBIGRCr8
mRatBN7.214102,513,054 - 102,513,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,513,054 - 102,513,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14106,841,244 - 106,841,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,077,872 - 108,077,973 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,550,284 - 104,550,385 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,101,078 - 113,101,179 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,101,078 - 113,101,179 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014112,790,786 - 112,790,887 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14101,413,160 - 101,413,261 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
pancreatitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:20403161   PMID:20439489   PMID:20548288   PMID:23995054   PMID:29477872   PMID:33390770  


Genomics

Comparative Map Data
Mir216b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,714,026 - 106,714,127 (+)NCBIGRCr8
mRatBN7.214102,513,054 - 102,513,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,513,054 - 102,513,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14106,841,244 - 106,841,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,077,872 - 108,077,973 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,550,284 - 104,550,385 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,101,078 - 113,101,179 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,101,078 - 113,101,179 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014112,790,786 - 112,790,887 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14101,413,160 - 101,413,261 (+)NCBICelera
Cytogenetic Map14q22NCBI
MIR216B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38256,000,714 - 56,000,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl256,000,714 - 56,000,795 (-)EnsemblGRCh38hg38GRCh38
GRCh37256,227,849 - 56,227,930 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36256,081,352 - 56,081,433 (-)NCBINCBI36Build 36hg18NCBI36
Celera256,068,265 - 56,068,346 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,962,869 - 55,962,950 (-)NCBIHuRef
CHM1_1256,157,781 - 56,157,862 (-)NCBICHM1_1
T2T-CHM13v2.0255,997,657 - 55,997,738 (-)NCBIT2T-CHM13v2.0
Mir216b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,696,191 - 28,696,276 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1128,696,191 - 28,696,276 (+)EnsemblGRCm39 Ensembl
GRCm381128,746,191 - 28,746,276 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,746,191 - 28,746,276 (+)EnsemblGRCm38mm10GRCm38
MGSCv371128,646,191 - 28,646,276 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1131,118,150 - 31,118,235 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.23NCBI
MIR216B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,772,853 - 56,772,914 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1056,772,853 - 56,772,914 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1056,729,244 - 56,729,305 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01057,777,763 - 57,777,824 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11057,477,457 - 57,477,518 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,756,790 - 57,756,851 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01058,048,598 - 58,048,659 (-)NCBIUU_Cfam_GSD_1.0

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:4962
Count of gene targets:3355
Count of transcripts:3591
Interacting mature miRNAs:rno-miR-216b-3p, rno-miR-216b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system reproductive system
High
Medium
Low 1 2
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_037355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000054490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl14102,513,054 - 102,513,155 (+)Ensembl
Rnor_6.0 Ensembl14113,101,078 - 113,101,179 (+)Ensembl
RefSeq Acc Id: NR_037355
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814106,714,026 - 106,714,127 (+)NCBI
mRatBN7.214102,513,054 - 102,513,155 (+)NCBI
Rnor_6.014113,101,078 - 113,101,179 (+)NCBI
Rnor_5.014112,790,786 - 112,790,887 (+)NCBI
Celera14101,413,160 - 101,413,261 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:4888592 AgrOrtholog
BioCyc Gene G2FUF-14693 BioCyc
Ensembl Genes ENSRNOG00000036371 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000054490 ENTREZGENE
miRBase MI0015435 ENTREZGENE
NCBI Gene 100526583 ENTREZGENE
PhenoGen Mir216b PhenoGen
RatGTEx ENSRNOG00000036371 RatGTEx
RNAcentral URS000046CDA6 RNACentral
  URS000075A13F RNACentral
  URS000075BAFB RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir216b  microRNA 216b  Mir216b  microRNA mir-216b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-23 Mir216b  microRNA mir-216b      Symbol and Name status set to provisional 70820 PROVISIONAL