Gene: Hus1 (HUS1 checkpoint clamp component) Rattus norvegicus
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Symbol: Hus1
Name: HUS1 checkpoint clamp component
Description: INVOLVED IN cellular response to DNA damage stimulus (ortholog); cellular response to ionizing radiation (ortholog); DNA damage checkpoint (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; flutamide
AGR Description: Predicted to be involved in several processes, including DNA metabolic process, cellular response to ionizing radiation, and negative regulation of cell cycle; predicted to localize to the checkpoint clamp complex and site of double-strand break; orthologous to human HUS1 (HUS1 checkpoint clamp component).
Merged Description: Predicted to be involved in several processes, including DNA metabolic process, cellular response to ionizing radiation, and negative regulation of cell cycle; predicted to localize to the checkpoint clamp complex and site of double-strand break; orthologous to human HUS1 (HUS1 checkpoint clamp component); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: checkpoint protein HUS1; HUS1 checkpoint homolog; HUS1 checkpoint homolog (S. pombe); Hus1 homolog; LOC498411; similar to Hus1 homolog
Orthologs:
Homo sapiens (human) : HUS1 (HUS1 checkpoint clamp component)  HGNC  Alliance
Mus musculus (house mouse) : Hus1 (HUS1 checkpoint clamp component)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hus1 (HUS1 checkpoint clamp component)
Pan paniscus (bonobo/pygmy chimpanzee) : HUS1 (HUS1 checkpoint clamp component)
Canis lupus familiaris (dog) : HUS1 (HUS1 checkpoint clamp component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hus1 (HUS1 checkpoint clamp component)
Sus scrofa (pig) : HUS1 (HUS1 checkpoint clamp component)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01489,194,086 - 89,208,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01488,991,462 - 89,006,201 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,527,997 - 89,542,730 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1482,724,930 - 82,739,682 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hus1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1591976
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.