(+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of EGFR mRNA CTD PMID:17971868 (+)-Tetrandrine decreases phosphorylation ISO RGD:69152 6480464 tetrandrine results in decreased phosphorylation of EGFR protein CTD PMID:30549224 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:69152 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA more ... CTD PMID:17616711 more ... (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:10511 6480464 epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 (-)-epigallocatechin 3-gallate increases expression ISO RGD:69152 6480464 epigallocatechin gallate results in increased expression of EGFR mRNA CTD PMID:22079256 (1->4)-beta-D-glucan multiple interactions ISO RGD:10511 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EGFR mRNA CTD PMID:36331819 (20R)-protopanaxadiol decreases activity ISO RGD:69152 6480464 protopanaxadiol results in decreased activity of EGFR protein CTD PMID:31805304 (20R)-protopanaxadiol multiple interactions ISO RGD:69152 6480464 protopanaxadiol results in decreased expression of and results in increased phosphorylation of EGFR protein CTD PMID:31805304 (20S)-ginsenoside Rg3 multiple interactions ISO RGD:69152 6480464 EGF protein promotes the reaction [ginsenoside Rg3 affects the phosphorylation of EGFR protein] more ... CTD PMID:25824408 (20S)-ginsenoside Rg3 affects phosphorylation ISO RGD:69152 6480464 ginsenoside Rg3 affects the phosphorylation of EGFR protein CTD PMID:25824408 (R)-noradrenaline multiple interactions EXP 6480464 EGFR protein inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form] CTD PMID:19168439 (S)-naringenin multiple interactions ISO RGD:69152 6480464 [naringenin co-treated with bisphenol A] results in increased expression of EGFR mRNA more ... CTD PMID:25866363 , PMID:36235125 (S)-nicotine increases phosphorylation ISO RGD:69152 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 (S)-nicotine multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases phosphorylation ISO RGD:69152 6480464 2 more ... CTD PMID:28426875 1,2,3,4,7,8-Hexachlorodibenzofuran decreases activity ISO RGD:10511 6480464 1 more ... CTD PMID:2718174 1,2-dichloroethane decreases expression ISO RGD:10511 6480464 ethylene dichloride results in decreased expression of EGFR mRNA CTD PMID:28189721 , PMID:28960355 1,2-dimethylhydrazine decreases expression ISO RGD:10511 6480464 1, 2-Dimethylhydrazine results in decreased expression of EGFR mRNA CTD PMID:22206623 1,2-naphthoquinone multiple interactions ISO RGD:69152 6480464 1 more ... CTD PMID:24067727 , PMID:33814511 1,2-naphthoquinone increases phosphorylation ISO RGD:69152 6480464 1, 2-naphthoquinone results in increased phosphorylation of EGFR protein CTD PMID:33814511 1,4-benzoquinone multiple interactions ISO RGD:69152 6480464 quinone promotes the reaction [1, 4-naphthoquinone results in increased phosphorylation of EGFR protein] CTD PMID:33814511 1,4-naphthoquinone multiple interactions ISO RGD:69152 6480464 1 more ... CTD PMID:33814511 1,4-naphthoquinone increases phosphorylation ISO RGD:69152 6480464 1, 4-naphthoquinone results in increased phosphorylation of EGFR protein CTD PMID:33814511 1-chloro-2,4-dinitrobenzene affects binding ISO RGD:69152 6480464 Dinitrochlorobenzene binds to EGFR protein CTD PMID:32991956 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:69152 6480464 lysophosphatidic acid results in increased phosphorylation of EGFR protein CTD PMID:23127547 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:69152 6480464 GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] more ... CTD PMID:23127547 16,16-dimethylprostaglandin E2 multiple interactions ISO RGD:10511 6480464 EGFR affects the reaction [16, 16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 17alpha-ethynylestradiol increases expression ISO RGD:10511 6480464 Ethinyl Estradiol results in increased expression of EGFR mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EGFR protein CTD PMID:2197011 , PMID:2786453 17alpha-ethynylestradiol increases stability EXP 6480464 Ethinyl Estradiol results in increased stability of EGFR protein CTD PMID:2197011 17alpha-ethynylestradiol affects expression ISO RGD:10511 6480464 Ethinyl Estradiol affects the expression of EGFR mRNA CTD PMID:17555576 17beta-estradiol multiple interactions ISO RGD:10511 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of EGFR mRNA] more ... CTD PMID:22414604 , PMID:25210133 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of EGFR mRNA CTD PMID:32145629 17beta-estradiol increases activity ISO RGD:69152 6480464 Estradiol results in increased activity of EGFR protein CTD PMID:15802018 17beta-estradiol increases phosphorylation ISO RGD:69152 6480464 Estradiol results in increased phosphorylation of EGFR protein CTD PMID:20005069 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EGFR mRNA CTD PMID:20068009 , PMID:31119341 17beta-estradiol multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein] CTD PMID:8888411 17beta-estradiol increases expression ISO RGD:69152 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:19619570 , PMID:31614463 17beta-estradiol decreases expression ISO RGD:69152 6480464 Estradiol results in decreased expression of EGFR mRNA, Estradiol results in decreased expression of EGFR protein CTD PMID:20005069 17beta-estradiol multiple interactions ISO RGD:69152 6480464 4-(6-bromo-1 more ... CTD PMID:17622325 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of EGFR mRNA, Estradiol results in increased expression of EGFR protein CTD PMID:35192832 , PMID:8888411 17beta-estradiol increases expression ISO RGD:10511 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:25210133 17beta-estradiol 17-glucosiduronic acid multiple interactions EXP 6480464 EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein] more ... CTD PMID:25813982 17beta-estradiol 3-benzoate increases expression EXP 6480464 estradiol 3-benzoate results in increased expression of EGFR protein CTD PMID:15778002 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions EXP 6480464 Metribolone results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:17272394 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:69152 6480464 Dihydrotestosterone results in increased expression of EGFR mRNA CTD PMID:29581250 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:10511 6480464 [cypermethrin results in decreased susceptibility to Dihydrotestosterone] which results in decreased phosphorylation of EGFR protein CTD PMID:30974244 2,2',4,4',5,5'-hexachlorobiphenyl affects localization ISO RGD:69152 6480464 2 more ... CTD PMID:19632255 2,2',4,4',5,5'-hexachlorobiphenyl affects binding ISO RGD:69152 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:69152 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation ISO RGD:69152 6480464 2 more ... CTD PMID:19632255 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:10511 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:69152 6480464 2 more ... CTD PMID:31675489 2,3,4,7,8-Pentachlorodibenzofuran decreases activity ISO RGD:10511 6480464 2 more ... CTD PMID:2718174 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69152 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR mRNA more ... CTD PMID:11309286 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases metabolic processing EXP 6480464 Tetrachlorodibenzodioxin results in increased metabolism of EGFR gene CTD PMID:32277265 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA CTD PMID:14708085 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10511 6480464 CSK protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] more ... CTD PMID:6309801 , PMID:9664232 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:10401681 , PMID:15592923 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69152 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR CTD PMID:1336723 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:69152 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:20971882 , PMID:26971374 2,3,7,8-tetrachlorodibenzodioxine affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9163677 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:22298810 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69152 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in decreased expression of EGFR protein CTD PMID:20959002 , PMID:8403215 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR protein more ... CTD PMID:11752688 more ... 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,5-hexanedione increases expression EXP 6480464 2, 5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:10900465 2-acetamidofluorene decreases expression EXP 6480464 2-Acetylaminofluorene results in decreased expression of EGFR mRNA CTD PMID:22213190 2-deoxy-D-glucose multiple interactions ISO RGD:69152 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 2-deoxy-D-glucose increases import ISO RGD:69152 6480464 EGFR protein mutant form results in increased import of Deoxyglucose CTD PMID:19625624 2-hydroxypropanoic acid decreases expression ISO RGD:69152 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 2-methoxy-17beta-estradiol decreases expression ISO RGD:69152 6480464 2-Methoxyestradiol results in decreased expression of EGFR mRNA, 2-Methoxyestradiol results in decreased expression of EGFR protein CTD PMID:30779072 2-nitrotoluene decreases expression ISO RGD:10511 6480464 2-nitrotoluene results in decreased expression of EGFR mRNA CTD PMID:15618236 3',5'-cyclic AMP multiple interactions ISO RGD:10511 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:69152 6480464 3 more ... CTD PMID:29329451 3,3',4,4',5-pentachlorobiphenyl affects binding ISO RGD:69152 6480464 3 more ... CTD PMID:29329451 3,3',5,5'-tetrabromobisphenol A increases phosphorylation ISO RGD:69152 6480464 tetrabromobisphenol A results in increased phosphorylation of EGFR protein CTD PMID:26718265 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:69152 6480464 bisindolylmaleimide I inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein], bisindolylmaleimide I inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of EGFR mRNA CTD PMID:28522335 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of EGFR mRNA CTD PMID:29094188 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of EGFR mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions ISO RGD:69152 6480464 EGFR protein affects the susceptibility to [Epirubicin co-treated with CMF regimen] CTD PMID:18768436 4,4'-diaminodiphenylmethane increases expression ISO RGD:10511 6480464 4, 4'-diaminodiphenylmethane results in increased expression of EGFR mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions ISO RGD:69152 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of EGFR gene more ... CTD PMID:31601247 , PMID:33605785 4,4'-sulfonyldiphenol increases expression ISO RGD:69152 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EGFR protein CTD PMID:31945527 , PMID:34186270 4,4'-sulfonyldiphenol increases expression ISO RGD:10511 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EGFR mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO RGD:69152 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein CTD PMID:16671086 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:69152 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 4-hydroxyphenyl retinamide increases expression ISO RGD:69152 6480464 Fenretinide results in increased expression of EGFR mRNA CTD PMID:16570282 4-hydroxyphenyl retinamide decreases expression ISO RGD:10511 6480464 Fenretinide results in decreased expression of EGFR mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO RGD:10511 6480464 4-nitrophenol results in increased expression of EGFR mRNA CTD PMID:34673133 4-nitrotoluene decreases expression ISO RGD:10511 6480464 4-nitrotoluene results in decreased expression of EGFR protein CTD PMID:15618236 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 4-tert-Octylphenol increases phosphorylation ISO RGD:69152 6480464 4-tert-octylphenol results in increased phosphorylation of EGFR protein CTD PMID:32466334 4-vinylcyclohexene dioxide affects expression ISO RGD:10511 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of EGFR mRNA CTD PMID:20829426 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases phosphorylation EXP 6480464 cholesterol alpha-oxide results in increased phosphorylation of EGFR protein CTD PMID:20466046 5-aza-2'-deoxycytidine increases expression ISO RGD:69152 6480464 Decitabine results in increased expression of EGFR mRNA CTD PMID:19151715 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 5-fluorouracil decreases response to substance ISO RGD:69152 6480464 EGFR gene polymorphism results in decreased susceptibility to Fluorouracil CTD PMID:19217205 5-fluorouracil decreases expression ISO RGD:69152 6480464 Fluorouracil results in decreased expression of EGFR protein CTD PMID:17918158 , PMID:17982676 5-fluorouracil increases phosphorylation ISO RGD:69152 6480464 Fluorouracil results in increased phosphorylation of EGFR protein CTD PMID:18794807 5-fluorouracil affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Fluorouracil CTD PMID:16836928 , PMID:17169374 5-fluorouracil multiple interactions ISO RGD:69152 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO RGD:69152 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:25625231 , PMID:30364229 6-chrysenamine multiple interactions ISO RGD:10511 6480464 6-chrysenamine inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of EGFR mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of EGFR mRNA CTD PMID:30047161 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:36863560 7,12-dimethyltetraphene decreases expression ISO RGD:10511 6480464 9 more ... CTD PMID:32553695 7-ketocholesterol increases phosphorylation EXP 6480464 7-ketocholesterol results in increased phosphorylation of EGFR protein CTD PMID:20466046 8-Br-cAMP increases expression ISO RGD:69152 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGFR mRNA CTD PMID:22079614 9,10-phenanthroquinone multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:32493877 9,10-phenanthroquinone increases phosphorylation ISO RGD:69152 6480464 9, 10-phenanthrenequinone results in increased phosphorylation of EGFR protein CTD PMID:32493877 9-cis-retinoic acid decreases expression ISO RGD:69152 6480464 Alitretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of EGFR mRNA CTD PMID:31881176 acetylsalicylic acid increases expression ISO RGD:69152 6480464 Aspirin results in increased expression of EGFR mRNA CTD PMID:15456535 acrolein increases activity ISO RGD:69152 6480464 Acrolein results in increased activity of EGFR protein CTD PMID:11329622 acrolein increases phosphorylation ISO RGD:10511 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20153347 acrolein increases phosphorylation ISO RGD:69152 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:11329622 , PMID:15531749 acrolein multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]], Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20359552 acrolein multiple interactions ISO RGD:69152 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA more ... CTD PMID:15531749 , PMID:32699268 acrylamide affects phosphorylation ISO RGD:69152 6480464 Acrylamide analog affects the phosphorylation of EGFR protein CTD PMID:11462982 acrylamide increases expression ISO RGD:69152 6480464 Acrylamide results in increased expression of EGFR protein CTD PMID:24508477 acrylamide multiple interactions ISO RGD:69152 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein], epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of EGFR protein] CTD PMID:24508477 acrylamide decreases phosphorylation ISO RGD:69152 6480464 Acrylamide analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 acteoside decreases phosphorylation ISO RGD:69152 6480464 acteoside results in decreased phosphorylation of EGFR protein CTD PMID:21756928 , PMID:21967610 acteoside multiple interactions ISO RGD:69152 6480464 acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein] more ... CTD PMID:21756928 , PMID:21967610 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein], Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 afatinib decreases activity ISO RGD:69152 6480464 afatinib results in decreased activity of EGFR protein, afatinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 , PMID:22242139 afatinib decreases phosphorylation ISO RGD:69152 6480464 afatinib results in decreased phosphorylation of EGFR protein CTD PMID:28787001 afimoxifene decreases response to substance ISO RGD:69152 6480464 EGFR protein results in decreased susceptibility to afimoxifene, EGFR results in decreased susceptibility to afimoxifene CTD PMID:18351453 , PMID:21233418 AH23848 multiple interactions ISO RGD:69152 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein], [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of and results in decreased expression of EGFR protein CTD PMID:19407222 AICA ribonucleotide multiple interactions ISO RGD:69152 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of EGFR mRNA CTD PMID:11507004 all-trans-4-oxoretinoic acid decreases expression ISO RGD:69152 6480464 4-oxoretinoic acid results in decreased expression of EGFR mRNA CTD PMID:15982314 all-trans-retinoic acid decreases expression ISO RGD:69152 6480464 Tretinoin metabolite results in decreased expression of EGFR mRNA, Tretinoin results in decreased expression of EGFR protein CTD PMID:15970678 more ... all-trans-retinoic acid increases expression ISO RGD:69152 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:21934132 , PMID:34742744 all-trans-retinoic acid increases phosphorylation ISO RGD:10511 6480464 Tretinoin results in increased phosphorylation of EGFR protein CTD PMID:16357442 all-trans-retinoic acid increases expression ISO RGD:10511 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:16604517 all-trans-retinoic acid multiple interactions ISO RGD:10511 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA, HBEGF protein promotes the reaction [Tretinoin results in increased phosphorylation of EGFR protein] CTD PMID:16357442 , PMID:30951980 all-trans-retinol increases expression EXP 6480464 Vitamin A deficiency results in increased expression of EGFR mRNA CTD PMID:7519440 alpha-naphthoflavone multiple interactions ISO RGD:69152 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 alpha-pinene multiple interactions ISO RGD:69152 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of EGFR mRNA CTD PMID:32699268 alprenolol multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Alprenolol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 alprenolol increases phosphorylation ISO RGD:69152 6480464 [Alprenolol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 aluminium oxide increases expression ISO RGD:69152 6480464 Aluminum Oxide results in increased expression of EGFR mRNA CTD PMID:19464052 AM-251 multiple interactions ISO RGD:69152 6480464 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein] more ... CTD PMID:27423937 AM-251 increases expression ISO RGD:69152 6480464 AM 251 results in increased expression of EGFR protein CTD PMID:27423937 amiodarone multiple interactions ISO RGD:69152 6480464 Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein], RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]] CTD PMID:26515726 amiodarone decreases phosphorylation ISO RGD:10511 6480464 Amiodarone results in decreased phosphorylation of EGFR protein CTD PMID:26515726 amiodarone decreases phosphorylation ISO RGD:69152 6480464 Amiodarone results in decreased phosphorylation of EGFR protein CTD PMID:26515726 amiodarone multiple interactions ISO RGD:10511 6480464 Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein] CTD PMID:26515726 amiodarone decreases expression ISO RGD:10511 6480464 Amiodarone results in decreased expression of EGFR mRNA CTD PMID:24535564 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of EGFR mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EGFR mRNA CTD PMID:16483693 ammonium chloride decreases expression EXP 6480464 Ammonium Chloride results in decreased expression of EGFR protein CTD PMID:16483693 amosite asbestos decreases phosphorylation ISO RGD:69152 6480464 Asbestos, Amosite results in decreased phosphorylation of EGFR protein CTD PMID:15626777 amosite asbestos increases expression EXP 6480464 Asbestos, Amosite results in increased expression of EGFR mRNA CTD PMID:22251266 amphibole asbestos increases expression EXP 6480464 Asbestos, Amphibole results in increased expression of EGFR mRNA CTD PMID:22251266 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression ISO RGD:69152 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA, pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:15923621 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression EXP 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA, pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:18332871 antimonite increases expression ISO RGD:69152 6480464 antimonite results in increased expression of EGFR protein CTD PMID:17400267 antirheumatic drug decreases expression ISO RGD:69152 6480464 Antirheumatic Agents results in decreased expression of EGFR mRNA CTD PMID:24449571 ANTU increases expression EXP 6480464 alpha-naphthyl thiourea results in increased expression of EGFR mRNA CTD PMID:10755703 apocynin multiple interactions ISO RGD:69152 6480464 acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 arachidonic acid multiple interactions EXP 6480464 5 more ... CTD PMID:15525798 arecoline multiple interactions ISO RGD:10511 6480464 [Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein more ... CTD PMID:26464283 aristolochic acid A decreases expression ISO RGD:69152 6480464 aristolochic acid I results in decreased expression of EGFR mRNA CTD PMID:33212167 arsane increases expression ISO RGD:69152 6480464 Arsenic results in increased expression of EGFR mRNA, Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 , PMID:19945496 arsane affects response to substance ISO RGD:69152 6480464 EGFR gene SNP affects the susceptibility to Arsenic CTD PMID:31864032 arsane multiple interactions ISO RGD:10511 6480464 Arsenic results in increased phosphorylation of and affects the localization of EGFR protein, RTKI cpd inhibits the reaction [Arsenic affects the localization of EGFR protein] CTD PMID:32159786 arsane decreases expression ISO RGD:69152 6480464 Arsenic results in decreased expression of EGFR mRNA CTD PMID:31739468 arsane multiple interactions ISO RGD:69152 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenic acid increases phosphorylation ISO RGD:69152 6480464 arsenic acid results in increased phosphorylation of EGFR protein CTD PMID:14674888 arsenic acid multiple interactions ISO RGD:69152 6480464 EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK1 protein], EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK3 protein] CTD PMID:14674888 arsenic atom increases expression ISO RGD:69152 6480464 Arsenic results in increased expression of EGFR mRNA, Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 , PMID:19945496 arsenic atom affects response to substance ISO RGD:69152 6480464 EGFR gene SNP affects the susceptibility to Arsenic CTD PMID:31864032 arsenic atom multiple interactions ISO RGD:10511 6480464 Arsenic results in increased phosphorylation of and affects the localization of EGFR protein, RTKI cpd inhibits the reaction [Arsenic affects the localization of EGFR protein] CTD PMID:32159786 arsenic atom multiple interactions ISO RGD:69152 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenic atom decreases expression ISO RGD:69152 6480464 Arsenic results in decreased expression of EGFR mRNA CTD PMID:31739468 arsenite(3-) decreases degradation ISO RGD:69152 6480464 arsenite results in decreased degradation of EGFR protein CTD PMID:17400267 arsenite(3-) increases methylation ISO RGD:69152 6480464 arsenite results in increased methylation of EGFR promoter CTD PMID:23974009 arsenite(3-) affects response to substance ISO RGD:69152 6480464 EGFR affects the susceptibility to arsenite CTD PMID:31773452 arsenite(3-) decreases expression ISO RGD:10511 6480464 arsenite results in decreased expression of EGFR mRNA CTD PMID:33053406 arsenite(3-) multiple interactions ISO RGD:69152 6480464 arsenite inhibits the reaction [G3BP1 protein binds to EGFR mRNA] more ... CTD PMID:14674888 more ... arsenite(3-) increases phosphorylation ISO RGD:69152 6480464 arsenite results in increased phosphorylation of EGFR protein CTD PMID:14674888 , PMID:17400267 arsenite(3-) increases expression ISO RGD:69152 6480464 arsenite results in increased expression of EGFR protein CTD PMID:17400267 arsenous acid decreases expression ISO RGD:10511 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 arsenous acid increases expression ISO RGD:69152 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 , PMID:29274334 arsenous acid increases phosphorylation ISO RGD:69152 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 arsenous acid multiple interactions ISO RGD:69152 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... arsenous acid decreases expression ISO RGD:69152 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA, Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... arsenous acid affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide, EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 , PMID:30237564 arsenous acid multiple interactions ISO RGD:10511 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 astragaloside IV multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein, [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 atenolol multiple interactions ISO RGD:69152 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 atorvastatin calcium multiple interactions ISO RGD:10511 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:18360054 ATP increases phosphorylation ISO RGD:69152 6480464 Adenosine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:26104857 ATP multiple interactions ISO RGD:69152 6480464 sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 atrazine increases expression ISO RGD:69152 6480464 Atrazine results in increased expression of EGFR mRNA CTD PMID:22378314 atrazine multiple interactions ISO RGD:69152 6480464 Atrazine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:29329451 atropine multiple interactions ISO RGD:69152 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 avobenzone increases expression ISO RGD:69152 6480464 avobenzone results in increased expression of EGFR mRNA CTD PMID:31016361 bafilomycin A1 multiple interactions ISO RGD:69152 6480464 bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 baicalein multiple interactions ISO RGD:69152 6480464 baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein], MIR3663 mRNA promotes the reaction [baicalein results in decreased phosphorylation of EGFR protein] CTD PMID:25625231 , PMID:33838155 baicalein decreases phosphorylation ISO RGD:69152 6480464 baicalein results in decreased phosphorylation of EGFR protein CTD PMID:33838155 baicalin multiple interactions ISO RGD:69152 6480464 baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 benzamide decreases activity ISO RGD:69152 6480464 benzamide analog results in decreased activity of EGFR protein CTD PMID:15186837 benzamidine decreases activity ISO RGD:69152 6480464 benzamidine analog results in decreased activity of EGFR protein CTD PMID:15186837 benzene decreases expression EXP 6480464 Benzene results in decreased expression of EGFR mRNA CTD PMID:17905399 benzo[a]pyrene increases phosphorylation ISO RGD:69152 6480464 Benzo(a)pyrene results in increased phosphorylation of EGFR protein CTD PMID:19181443 benzo[a]pyrene affects methylation ISO RGD:69152 6480464 Benzo(a)pyrene affects the methylation of EGFR promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:10511 6480464 Benzo(a)pyrene results in decreased methylation of EGFR 3' UTR, Benzo(a)pyrene results in decreased methylation of EGFR exon CTD PMID:27901495 benzo[a]pyrene increases response to substance ISO RGD:69152 6480464 EGFR protein results in increased susceptibility to Benzo(a)pyrene CTD PMID:8608954 benzo[a]pyrene multiple interactions ISO RGD:10511 6480464 AHR protein affects the reaction [Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein]], Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 benzo[a]pyrene decreases expression ISO RGD:10511 6480464 Benzo(a)pyrene metabolite results in decreased expression of EGFR mRNA, Benzo(a)pyrene results in decreased expression of EGFR mRNA CTD PMID:19770486 more ... benzo[a]pyrene increases expression ISO RGD:69152 6480464 Benzo(a)pyrene results in increased expression of EGFR mRNA CTD PMID:19181443 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:69152 6480464 7 more ... CTD PMID:22457794 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:10511 6480464 7 more ... CTD PMID:6309801 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:69152 6480464 7 more ... CTD PMID:19150397 benzo[b]fluoranthene multiple interactions ISO RGD:69152 6480464 benzo(b)fluoranthene affects the localization of and results in increased expression of EGFR protein CTD PMID:21776270 benzo[b]fluoranthene decreases expression ISO RGD:10511 6480464 benzo(b)fluoranthene results in decreased expression of EGFR mRNA CTD PMID:26377693 benzoic acid multiple interactions ISO RGD:10511 6480464 Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 berberine decreases expression ISO RGD:69152 6480464 Berberine results in decreased expression of EGFR protein CTD PMID:33325633 betulin multiple interactions ISO RGD:69152 6480464 [Gefitinib co-treated with betulin] results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulin decreases phosphorylation ISO RGD:69152 6480464 betulin results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulinic acid multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16077934 , PMID:30136359 betulinic acid increases phosphorylation ISO RGD:69152 6480464 Betulinic Acid results in increased phosphorylation of EGFR protein CTD PMID:16077934 bicalutamide multiple interactions ISO RGD:69152 6480464 bicalutamide inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]] more ... CTD PMID:29383186 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of EGFR mRNA, Diethylhexyl Phthalate results in decreased expression of EGFR protein CTD PMID:2404574 , PMID:34197824 bis(2-ethylhexyl) phthalate increases expression ISO RGD:69152 6480464 Diethylhexyl Phthalate results in increased expression of EGFR mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA more ... CTD PMID:25607892 , PMID:34197824 bisdemethoxycurcumin decreases expression ISO RGD:69152 6480464 bisdemethoxycurcumin results in decreased expression of EGFR protein modified form CTD PMID:35735092 bisphenol A decreases expression ISO RGD:69152 6480464 bisphenol A results in decreased expression of EGFR mRNA, bisphenol A results in decreased expression of EGFR protein CTD PMID:20678512 , PMID:31675489 bisphenol A increases phosphorylation ISO RGD:10511 6480464 bisphenol A results in increased phosphorylation of EGFR protein CTD PMID:32353937 bisphenol A decreases methylation ISO RGD:69152 6480464 bisphenol A results in decreased methylation of EGFR gene CTD PMID:31601247 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EGFR mRNA CTD PMID:32145629 bisphenol A increases expression ISO RGD:10511 6480464 bisphenol A results in increased expression of EGFR mRNA CTD PMID:30951980 , PMID:32353937 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:69152 6480464 bisphenol A results in increased expression of EGFR mRNA, bisphenol A results in increased expression of EGFR protein CTD PMID:29275510 more ... bisphenol A multiple interactions ISO RGD:69152 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [bisphenol A results in increased phosphorylation of EGFR protein] more ... CTD PMID:28426875 more ... bisphenol A increases phosphorylation ISO RGD:69152 6480464 bisphenol A results in increased phosphorylation of EGFR protein CTD PMID:28426875 more ... bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EGFR gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EGFR mRNA, bisphenol A results in increased expression of EGFR protein CTD PMID:25181051 , PMID:31771501 bisphenol A decreases expression ISO RGD:10511 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:26063408 , PMID:32156529 bisphenol F increases expression ISO RGD:10511 6480464 bisphenol F results in increased expression of EGFR mRNA CTD PMID:30951980 bisphenol F multiple interactions ISO RGD:10511 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA CTD PMID:30951980 bosutinib decreases activity ISO RGD:10511 6480464 bosutinib results in decreased activity of EGFR protein CTD PMID:18385429 butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:11134345 , PMID:15525798 butane-2,3-dione multiple interactions ISO RGD:69152 6480464 N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Diacetyl results in increased phosphorylation of EGFR protein] CTD PMID:30851105 butane-2,3-dione increases phosphorylation ISO RGD:69152 6480464 Diacetyl results in increased phosphorylation of EGFR protein CTD PMID:30851105 butylated hydroxyanisole multiple interactions ISO RGD:10511 6480464 Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:21220312 butylated hydroxyanisole multiple interactions ISO RGD:69152 6480464 Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of EGFR protein], Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of EGFR protein] CTD PMID:17028263 Butylbenzyl phthalate multiple interactions ISO RGD:69152 6480464 fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 Butylbenzyl phthalate increases phosphorylation ISO RGD:69152 6480464 butylbenzyl phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 cadmium atom decreases expression ISO RGD:10511 6480464 Cadmium results in decreased expression of EGFR mRNA CTD PMID:22666406 cadmium atom increases phosphorylation ISO RGD:69152 6480464 Cadmium results in increased phosphorylation of EGFR protein CTD PMID:26514923 cadmium atom multiple interactions ISO RGD:69152 6480464 4-(6-bromo-1 more ... CTD PMID:25343777 more ... cadmium atom increases activity ISO RGD:69152 6480464 Cadmium results in increased activity of EGFR protein CTD PMID:25343777 cadmium dichloride increases expression ISO RGD:69152 6480464 Cadmium Chloride results in increased expression of EGFR, Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:18560533 more ... cadmium dichloride increases phosphorylation ISO RGD:69152 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:25118938 , PMID:26385184 cadmium dichloride increases phosphorylation ISO RGD:10511 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:23948867 cadmium dichloride increases expression ISO RGD:10511 6480464 Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:23948867 cadmium dichloride multiple interactions ISO RGD:69152 6480464 4-(6-bromo-1 more ... CTD PMID:23673518 more ... cadmium dichloride multiple interactions ISO RGD:10511 6480464 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:23376140 , PMID:23948867 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:19233221 cadmium dichloride multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein], RTKI cpd inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 calcitriol increases expression ISO RGD:69152 6480464 Calcitriol results in increased expression of EGFR mRNA CTD PMID:21592394 calcitriol multiple interactions EXP 6480464 Calcitriol results in increased expression of and binds to EGFR protein CTD PMID:3498716 calcitriol multiple interactions ISO RGD:69152 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 calcium atom multiple interactions EXP 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 calcium silicate increases activity ISO RGD:69152 6480464 calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 calcium(0) multiple interactions EXP 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 canertinib decreases phosphorylation ISO RGD:69152 6480464 Canertinib results in decreased phosphorylation of EGFR protein CTD PMID:15956251 canertinib multiple interactions ISO RGD:10511 6480464 Canertinib inhibits the reaction [Acetaminophen affects the localization of EGFR protein], Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:28123000 canertinib decreases activity ISO RGD:69152 6480464 Canertinib results in decreased activity of EGFR protein, Canertinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 canertinib multiple interactions ISO RGD:69152 6480464 Canertinib inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18927496 cannabidiol multiple interactions ISO RGD:69152 6480464 [Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA more ... CTD PMID:31250491 more ... capsaicin decreases expression EXP 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:14521749 capsaicin multiple interactions ISO RGD:10511 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 capsaicin increases phosphorylation ISO RGD:69152 6480464 Capsaicin results in increased phosphorylation of EGFR protein CTD PMID:20619260 , PMID:20660715 capsaicin decreases expression ISO RGD:69152 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:19855437 capsaicin multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein] more ... CTD PMID:20619260 more ... carbon nanotube affects expression ISO RGD:10511 6480464 Nanotubes, Carbon affects the expression of EGFR mRNA CTD PMID:23845593 carbon nanotube increases expression ISO RGD:10511 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carvacrol increases phosphorylation ISO RGD:69152 6480464 carvacrol results in increased phosphorylation of EGFR protein CTD PMID:32535744 carvacrol multiple interactions ISO RGD:69152 6480464 KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein], TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein] CTD PMID:32535744 carvedilol multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 carvedilol increases phosphorylation ISO RGD:69152 6480464 [carvedilol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 casticin decreases expression ISO RGD:10511 6480464 casticin results in decreased expression of EGFR protein CTD PMID:28444820 celastrol multiple interactions ISO RGD:69152 6480464 [Sulfasalazine co-treated with celastrol] affects the expression of EGFR protein, [Sulfasalazine co-treated with celastrol] results in decreased expression of EGFR protein CTD PMID:20007406 celastrol decreases expression ISO RGD:69152 6480464 celastrol results in decreased expression of EGFR protein CTD PMID:17010675 celecoxib multiple interactions EXP 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein more ... CTD PMID:15309881 , PMID:17908994 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of EGFR mRNA CTD PMID:23125180 chloroquine multiple interactions ISO RGD:69152 6480464 Chloroquine inhibits the reaction [EGF protein results in decreased expression of EGFR protein] more ... CTD PMID:20056314 more ... chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22689575 chloroquine decreases expression ISO RGD:69152 6480464 Chloroquine results in decreased expression of EGFR protein CTD PMID:20332299 chlorothalonil decreases phosphorylation ISO RGD:69152 6480464 tetrachloroisophthalonitrile results in decreased phosphorylation of EGFR protein CTD PMID:28426875 chlorpyrifos increases phosphorylation ISO RGD:69152 6480464 Chlorpyrifos results in increased phosphorylation of EGFR protein CTD PMID:26514924 cholesterol multiple interactions ISO RGD:10511 6480464 [Cholesterol co-treated with 1, 2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of EGFR mRNA CTD PMID:22129739 choline multiple interactions ISO RGD:10511 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 chromium(6+) increases expression ISO RGD:69152 6480464 chromium hexavalent ion results in increased expression of EGFR mRNA CTD PMID:19616015 chromium(6+) increases phosphorylation ISO RGD:10511 6480464 chromium hexavalent ion results in increased phosphorylation of EGFR protein CTD PMID:25477514 chromium(6+) decreases expression ISO RGD:69152 6480464 chromium hexavalent ion results in decreased expression of EGFR mRNA CTD PMID:18053681 chrysin multiple interactions ISO RGD:69152 6480464 chrysin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 ciglitazone multiple interactions ISO RGD:69152 6480464 ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 ciglitazone decreases expression ISO RGD:69152 6480464 ciglitazone results in decreased expression of EGFR protein CTD PMID:21080969 ciguatoxin CTX1B affects expression ISO RGD:10511 6480464 Ciguatoxins affects the expression of EGFR mRNA CTD PMID:18353800 cimetidine multiple interactions ISO RGD:69152 6480464 Cimetidine inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 cimetidine multiple interactions ISO RGD:10511 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 Cinobufagin decreases expression ISO RGD:69152 6480464 cinobufagin results in decreased expression of EGFR protein CTD PMID:34619160 ciprofibrate decreases expression EXP 6480464 ciprofibrate results in decreased expression of EGFR protein CTD PMID:2404574 cisplatin multiple interactions ISO RGD:69152 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... cisplatin multiple interactions ISO RGD:10511 6480464 Cisplatin promotes the reaction [PRKDC protein binds to EGFR protein] CTD PMID:21266349 cisplatin increases response to substance ISO RGD:69152 6480464 EGFR protein results in increased susceptibility to Cisplatin CTD PMID:21324906 cisplatin affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Cisplatin CTD PMID:21431282 cisplatin decreases response to substance ISO RGD:69152 6480464 EGFR mRNA results in decreased susceptibility to Cisplatin, EGFR results in decreased susceptibility to Cisplatin CTD PMID:18337622 more ... cisplatin increases phosphorylation ISO RGD:69152 6480464 Cisplatin results in increased phosphorylation of EGFR protein CTD PMID:20726858 clofibrate decreases expression ISO RGD:10511 6480464 Clofibrate results in decreased expression of EGFR mRNA CTD PMID:17585979 clofibrate decreases expression ISO RGD:69152 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:21080969 clofibrate multiple interactions ISO RGD:69152 6480464 Clofibrate inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:2404574 clofibrate multiple interactions ISO RGD:10511 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA] CTD PMID:17585979 cobalt dichloride increases expression ISO RGD:69152 6480464 cobaltous chloride results in increased expression of EGFR mRNA CTD PMID:19376846 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of EGFR mRNA CTD PMID:24386269 cocaine decreases expression ISO RGD:69152 6480464 Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 copper atom multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper atom decreases expression ISO RGD:10511 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(0) multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper(0) decreases expression ISO RGD:10511 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(II) sulfate increases phosphorylation ISO RGD:69152 6480464 Copper Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 coumarin affects phosphorylation ISO RGD:69152 6480464 coumarin affects the phosphorylation of EGFR protein CTD PMID:35688186 crizotinib decreases response to substance ISO RGD:69152 6480464 EGFR protein mutant form results in decreased susceptibility to crizotinib, EGFR protein results in decreased susceptibility to crizotinib CTD PMID:21791641 , PMID:22235099 crizotinib multiple interactions ISO RGD:69152 6480464 [EGFR protein results in increased phosphorylation of EGFR protein] which results in decreased susceptibility to crizotinib more ... CTD PMID:22277784 , PMID:22553343 crocidolite asbestos increases activity ISO RGD:69152 6480464 Asbestos, Crocidolite results in increased activity of EGFR protein CTD PMID:21762757 crocidolite asbestos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Asbestos more ... CTD PMID:10516208 , PMID:26368632 crocidolite asbestos increases expression EXP 6480464 Asbestos more ... CTD PMID:10516208 more ... crocidolite asbestos increases activity ISO RGD:10511 6480464 Asbestos, Crocidolite results in increased activity of EGFR protein CTD PMID:15520183 crocidolite asbestos multiple interactions ISO RGD:10511 6480464 Acetylcysteine inhibits the reaction [Asbestos more ... CTD PMID:12154012 , PMID:15520183 crocidolite asbestos increases phosphorylation ISO RGD:10511 6480464 Asbestos, Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:14737115 crocidolite asbestos increases phosphorylation ISO RGD:69152 6480464 Asbestos, Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:16908449 , PMID:32006662 crocidolite asbestos affects binding ISO RGD:69152 6480464 Asbestos, Crocidolite binds to EGFR protein CTD PMID:23672436 crocidolite asbestos increases expression ISO RGD:69152 6480464 Asbestos, Crocidolite results in increased expression of EGFR protein CTD PMID:21570478 crocidolite asbestos multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:15626777 , PMID:16908449 Cryptotanshinone multiple interactions ISO RGD:69152 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in increased expression of EGFR protein modified form] CTD PMID:30208247 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of EGFR mRNA CTD PMID:26577399 curcumin multiple interactions ISO RGD:69152 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein] more ... CTD PMID:10851300 more ... curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:17372590 , PMID:18332871 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of EGFR mRNA, Curcumin results in decreased expression of EGFR protein CTD PMID:18332871 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA] CTD PMID:18006644 curcumin decreases phosphorylation ISO RGD:69152 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:15486348 , PMID:34994998 curcumin decreases expression ISO RGD:69152 6480464 Curcumin analog results in decreased expression of EGFR mRNA more ... CTD PMID:15486348 more ... cyanocob(III)alamin multiple interactions ISO RGD:10511 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 cycloheximide increases expression ISO RGD:69152 6480464 Cycloheximide results in increased expression of EGFR mRNA CTD PMID:15228094 cycloheximide multiple interactions ISO RGD:69152 6480464 Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein] CTD PMID:26368632 cyclophosphamide multiple interactions ISO RGD:69152 6480464 EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 cyclosporin A increases expression ISO RGD:69152 6480464 Cyclosporine results in increased expression of EGFR mRNA CTD PMID:20106945 cyclosporin A increases phosphorylation ISO RGD:10511 6480464 Cyclosporine results in increased phosphorylation of EGFR protein CTD PMID:32866465 cyclosporin A decreases expression ISO RGD:10511 6480464 Cyclosporine results in decreased expression of EGFR mRNA CTD PMID:19770486 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of EGFR mRNA, cypermethrin results in decreased expression of EGFR protein CTD PMID:22048644 cypermethrin multiple interactions ISO RGD:10511 6480464 [cypermethrin results in decreased susceptibility to Dihydrotestosterone] which results in decreased phosphorylation of EGFR protein CTD PMID:30974244 cypermethrin decreases phosphorylation EXP 6480464 cypermethrin results in decreased phosphorylation of EGFR protein CTD PMID:22048644 cypermethrin affects binding EXP 6480464 cypermethrin binds to EGFR protein CTD PMID:22048644 cytochalasin B multiple interactions ISO RGD:69152 6480464 Cytochalasin B inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 cytochalasin D multiple interactions ISO RGD:69152 6480464 Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 dacomitinib multiple interactions ISO RGD:10511 6480464 dacomitinib inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:27491023 daidzein multiple interactions ISO RGD:69152 6480464 [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 DDE multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 deguelin decreases expression ISO RGD:69152 6480464 deguelin metabolite results in decreased expression of EGFR protein, deguelin results in decreased expression of EGFR protein CTD PMID:19139008 dehydroepiandrosterone multiple interactions ISO RGD:69152 6480464 EGFR protein promotes the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA] CTD PMID:25969534 delphinidin decreases phosphorylation ISO RGD:69152 6480464 delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 deoxycholic acid increases activity ISO RGD:69152 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:16213893 deoxycholic acid multiple interactions ISO RGD:69152 6480464 Deoxycholic Acid results in decreased glycosylation of and results in decreased expression of EGFR protein more ... CTD PMID:14747693 , PMID:22223758 deoxycholic acid increases activity EXP 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:14747693 deoxycholic acid decreases response to substance ISO RGD:69152 6480464 EGFR protein results in decreased susceptibility to Deoxycholic Acid CTD PMID:12507930 deoxycholic acid increases phosphorylation ISO RGD:69152 6480464 Deoxycholic Acid results in increased phosphorylation of EGFR protein CTD PMID:14747693 deoxynivalenol decreases expression ISO RGD:69152 6480464 deoxynivalenol results in decreased expression of EGFR protein CTD PMID:33890134 desferrioxamine B multiple interactions ISO RGD:69152 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA more ... CTD PMID:15626777 , PMID:35690295 dexamethasone multiple interactions ISO RGD:69152 6480464 Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]] more ... CTD PMID:10807665 dexamethasone multiple interactions EXP 6480464 Dexamethasone results in decreased phosphorylation of and results in decreased activity of EGFR protein CTD PMID:15556944 Diallyl sulfide decreases expression ISO RGD:69152 6480464 allyl sulfide results in decreased expression of EGFR protein CTD PMID:34724321 diallyl trisulfide decreases expression ISO RGD:69152 6480464 diallyl trisulfide results in decreased expression of EGFR protein CTD PMID:23754639 diarsenic trioxide increases phosphorylation ISO RGD:69152 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 diarsenic trioxide decreases expression ISO RGD:10511 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 diarsenic trioxide multiple interactions ISO RGD:69152 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... diarsenic trioxide affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide, EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 , PMID:30237564 diarsenic trioxide decreases expression ISO RGD:69152 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA, Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... diarsenic trioxide multiple interactions ISO RGD:10511 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 diarsenic trioxide increases expression ISO RGD:69152 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 , PMID:29274334 diazinon affects expression EXP 6480464 Diazinon affects the expression of EGFR mRNA CTD PMID:22546817 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:16391241 dibenziodolium multiple interactions ISO RGD:69152 6480464 diphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 dibutyl phthalate multiple interactions ISO RGD:69152 6480464 fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 dibutyl phthalate increases phosphorylation ISO RGD:69152 6480464 Dibutyl Phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 diclofenac increases expression ISO RGD:10511 6480464 Diclofenac results in increased expression of EGFR mRNA CTD PMID:26934552 dicrotophos increases expression ISO RGD:69152 6480464 dicrotophos results in increased expression of EGFR mRNA CTD PMID:28302478 Didecyldimethylammonium decreases expression ISO RGD:69152 6480464 didecyldimethylammonium results in decreased expression of EGFR protein CTD PMID:32763356 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of EGFR mRNA CTD PMID:22546817 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EGFR mRNA CTD PMID:17011747 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of EGFR mRNA CTD PMID:16122865 dioxygen multiple interactions ISO RGD:69152 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of EGFR mRNA more ... CTD PMID:21300668 , PMID:32992648 disodium selenite decreases expression ISO RGD:10511 6480464 Sodium Selenite results in decreased expression of EGFR mRNA CTD PMID:23274088 dobutamine decreases response to substance ISO RGD:10511 6480464 EGFR gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:18599591 dobutamine multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 dorsomorphin multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases phosphorylation ISO RGD:69152 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin affects expression ISO RGD:69152 6480464 Doxorubicin affects the expression of EGFR protein CTD PMID:35218280 doxorubicin decreases expression ISO RGD:69152 6480464 Doxorubicin results in decreased expression of EGFR mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:69152 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:30031762 doxorubicin increases expression ISO RGD:10511 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:25896364 doxorubicin increases phosphorylation ISO RGD:10511 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:15843167 doxorubicin multiple interactions ISO RGD:69152 6480464 [[Gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin more ... CTD PMID:15981280 more ... elemental selenium decreases expression ISO RGD:69152 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 epoxiconazole multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 epoxiconazole decreases expression ISO RGD:10511 6480464 epoxiconazole results in decreased expression of EGFR mRNA CTD PMID:35436446 equol multiple interactions ISO RGD:69152 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased chemical synthesis of Oxygen] more ... CTD PMID:21300668 Erionite increases expression EXP 6480464 erionite results in increased expression of EGFR protein CTD PMID:26368632 erlotinib hydrochloride multiple interactions ISO RGD:69152 6480464 [Erlotinib Hydrochloride results in decreased activity of EGFR protein] which results in decreased expression of RAD50 protein more ... CTD PMID:19168569 more ... erlotinib hydrochloride decreases expression ISO RGD:69152 6480464 Erlotinib Hydrochloride results in decreased expression of EGFR protein modified form CTD PMID:30136359 erlotinib hydrochloride decreases response to substance ISO RGD:69152 6480464 EGFR protein mutant form results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:16407879 erlotinib hydrochloride decreases phosphorylation ISO RGD:69152 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of EGFR protein CTD PMID:16891461 more ... erlotinib hydrochloride decreases activity ISO RGD:69152 6480464 Erlotinib Hydrochloride results in decreased activity of EGFR protein CTD PMID:12907618 more ... erlotinib hydrochloride affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Erlotinib Hydrochloride, EGFR protein mutant form affects the susceptibility to Erlotinib Hydrochloride CTD PMID:21080748 estrone multiple interactions ISO RGD:10511 6480464 Estrone inhibits the reaction [LEPR gene mutant form inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein]], Estrone inhibits the reaction [LEPR gene mutant form results in decreased expression of EGFR mRNA] CTD PMID:1753381 ethanol increases expression EXP 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:15353170 ethanol increases expression ISO RGD:10511 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:69152 6480464 [Ethanol co-treated with CYP2E1 protein] results in increased phosphorylation of EGFR protein CTD PMID:22222162 ethanol decreases expression ISO RGD:10511 6480464 Ethanol results in decreased expression of EGFR mRNA CTD PMID:19167417 etoposide decreases expression ISO RGD:69152 6480464 Etoposide results in decreased expression of EGFR mRNA, Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 eugenol decreases expression ISO RGD:10511 6480464 Eugenol results in decreased expression of EGFR protein CTD PMID:15618236 eugenol increases expression ISO RGD:10511 6480464 Eugenol results in increased expression of EGFR mRNA CTD PMID:15618236 everolimus increases expression ISO RGD:69152 6480464 Everolimus results in increased expression of EGFR mRNA, Everolimus results in increased expression of EGFR protein CTD PMID:28711525 everolimus multiple interactions ISO RGD:69152 6480464 platycodin D inhibits the reaction [Everolimus results in increased expression of EGFR protein] CTD PMID:28711525 Evodiamine multiple interactions ISO RGD:10511 6480464 EGFR mutant form inhibits the reaction [evodiamine results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:19854188 Evodiamine increases phosphorylation ISO RGD:10511 6480464 evodiamine results in increased phosphorylation of EGFR protein CTD PMID:19854188 fenamidone increases expression ISO RGD:10511 6480464 fenamidone results in increased expression of EGFR mRNA CTD PMID:27029645 fenofibrate decreases expression ISO RGD:10511 6480464 Fenofibrate results in decreased expression of EGFR mRNA CTD PMID:11798191 ferric oxide increases phosphorylation ISO RGD:10511 6480464 ferric oxide analog results in increased phosphorylation of EGFR protein CTD PMID:24068039 fisetin multiple interactions ISO RGD:69152 6480464 fisetin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of EGFR protein modified form] CTD PMID:31606474 fluoranthene multiple interactions ISO RGD:10511 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of EGFR mRNA CTD PMID:28329830 fluoxetine increases phosphorylation ISO RGD:10511 6480464 Fluoxetine results in increased phosphorylation of EGFR protein CTD PMID:18758753 fluoxetine multiple interactions ISO RGD:10511 6480464 [[Fluoxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:18758753 , PMID:19662385 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of EGFR mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:10511 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA more ... CTD PMID:23255615 , PMID:33549593 folic acid decreases expression ISO RGD:10511 6480464 Folic Acid results in decreased expression of EGFR mRNA CTD PMID:25629700 formononetin decreases phosphorylation ISO RGD:69152 151357000 formononetin decreases phosphorylation of EGFR protein in lung RGD fulvestrant multiple interactions ISO RGD:69152 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of EGFR gene more ... CTD PMID:22552774 more ... furan decreases expression EXP 6480464 furan results in decreased expression of EGFR mRNA CTD PMID:25539665 galangin multiple interactions ISO RGD:69152 6480464 galangin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 galaxolide increases expression ISO RGD:69152 6480464 galaxolide results in increased expression of EGFR mRNA CTD PMID:34687775 galaxolide multiple interactions ISO RGD:69152 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of EGFR mRNA CTD PMID:34687775 gallic acid multiple interactions ISO RGD:69152 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:27087131 , PMID:27634460 gedunin decreases expression ISO RGD:69152 6480464 gedunin results in decreased expression of EGFR protein CTD PMID:17010675 gefitinib decreases response to substance ISO RGD:69152 6480464 EGFR gene mutant form results in decreased susceptibility to Gefitinib, EGFR protein mutant form results in decreased susceptibility to Gefitinib CTD PMID:16740687 more ... gefitinib decreases activity EXP 6480464 Gefitinib results in decreased activity of EGFR protein CTD PMID:29228391 , PMID:32370496 gefitinib multiple interactions EXP 6480464 gefitinib inhibits the reaction [HBEGF protein inhibits the reaction [sodium arsenite results in decreased phosphorylation of and results in decreased activity of EGFR protein]] CTD PMID:29228391 gefitinib decreases activity ISO RGD:69152 6480464 Gefitinib results in decreased activity of EGFR protein CTD PMID:17938326 more ... gefitinib decreases phosphorylation ISO RGD:69152 6480464 Gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:13680161 more ... gefitinib decreases phosphorylation EXP 6480464 gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:18375820 gefitinib decreases expression EXP 6480464 gefitinib results in decreased expression of EGFR protein modified form CTD PMID:15660382 gefitinib multiple interactions ISO RGD:10511 6480464 [Gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene more ... CTD PMID:15841081 more ... gefitinib decreases expression ISO RGD:69152 6480464 Gefitinib results in decreased expression of EGFR protein modified form CTD PMID:19288272 , PMID:30136359 gefitinib multiple interactions ISO RGD:69152 6480464 [[Gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin more ... CTD PMID:13680161 more ... gefitinib increases response to substance ISO RGD:69152 6480464 EGFR gene mutant form results in increased susceptibility to gefitinib more ... CTD PMID:16115929 more ... gefitinib affects response to substance ISO RGD:69152 6480464 EGFR gene mutant form affects the susceptibility to Gefitinib more ... CTD PMID:15976335 more ... geldanamycin multiple interactions ISO RGD:69152 6480464 geldanamycin promotes the reaction [Sulfasalazine results in decreased expression of EGFR protein] CTD PMID:20007406 geldanamycin multiple interactions EXP 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9605431 geldanamycin multiple interactions ISO RGD:10511 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9664232 geldanamycin decreases expression ISO RGD:69152 6480464 geldanamycin results in decreased expression of EGFR protein CTD PMID:20007406 gemcitabine multiple interactions ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... gemcitabine decreases expression ISO RGD:69152 6480464 Gemcitabine results in decreased expression of EGFR mRNA, Gemcitabine results in decreased expression of EGFR protein CTD PMID:17146438 , PMID:20103597 gemcitabine increases degradation ISO RGD:69152 6480464 Gemcitabine results in increased degradation of EGFR protein CTD PMID:17146438 gemcitabine increases expression ISO RGD:69152 6480464 Gemcitabine results in increased expression of EGFR mRNA CTD PMID:17146438 gemcitabine increases phosphorylation ISO RGD:69152 6480464 Gemcitabine results in increased phosphorylation of EGFR protein CTD PMID:17146438 , PMID:20726858 genistein multiple interactions ISO RGD:69152 6480464 [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 genistein multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] CTD PMID:19059320 genistein increases expression EXP 6480464 Genistein results in increased expression of EGFR protein CTD PMID:15781664 genistein decreases expression ISO RGD:10511 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:11880592 genistein decreases expression ISO RGD:69152 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:15257099 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of EGFR mRNA CTD PMID:22061828 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of EGFR mRNA CTD PMID:24136188 glutathione multiple interactions ISO RGD:69152 6480464 Glutathione inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] CTD PMID:14660655 glutathione multiple interactions ISO RGD:10511 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein, [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 glycine betaine multiple interactions ISO RGD:10511 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 glyphosate decreases expression ISO RGD:69152 6480464 glyphosate results in decreased expression of EGFR mRNA CTD PMID:31295307 Goe 6976 multiple interactions ISO RGD:69152 6480464 Go 6976 inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein], Go 6976 inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [EGF protein binds to and results in increased localization of EGFR protein] CTD PMID:11134345 gold atom multiple interactions ISO RGD:69152 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 gold(0) multiple interactions ISO RGD:69152 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 helioxanthin multiple interactions ISO RGD:10511 6480464 [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the localization of EGFR protein modified form, helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein] CTD PMID:26464283 heparin decreases expression ISO RGD:69152 6480464 Heparin results in decreased expression of EGFR mRNA, Heparin results in decreased expression of EGFR protein CTD PMID:16475731 heparin increases phosphorylation ISO RGD:69152 6480464 Heparin results in increased phosphorylation of EGFR protein CTD PMID:16556679 herbicide decreases expression EXP 6480464 Herbicides results in decreased expression of EGFR mRNA CTD PMID:32360609 hexachlorobenzene multiple interactions ISO RGD:69152 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein] more ... CTD PMID:21205633 , PMID:23462309 hexachlorobenzene increases expression ISO RGD:10511 6480464 Hexachlorobenzene results in increased expression of EGFR mRNA CTD PMID:28923513 hexachlorobenzene multiple interactions ISO RGD:10511 6480464 Hexachlorobenzene affects the reaction [AHR protein affects the expression of EGFR mRNA] CTD PMID:28923513 hexachlorobenzene multiple interactions EXP 6480464 AG 1879 inhibits the reaction [SRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18295415 , PMID:22245120 hexachlorobenzene increases phosphorylation EXP 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:18295415 hexachlorobenzene increases phosphorylation ISO RGD:69152 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:21205633 hexadecanoic acid multiple interactions ISO RGD:69152 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 histamine multiple interactions ISO RGD:69152 6480464 EGFR protein affects the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 hyaluronic acid multiple interactions ISO RGD:69152 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 hydrogen chloride multiple interactions EXP 6480464 Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] more ... CTD PMID:15309881 hydrogen chloride increases expression EXP 6480464 Hydrochloric Acid results in increased expression of EGFR protein CTD PMID:15309881 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:19885844 hydrogen peroxide affects expression ISO RGD:69152 6480464 Hydrogen Peroxide affects the expression of EGFR protein CTD PMID:21179406 hydrogen peroxide multiple interactions ISO RGD:69152 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:10640773 more ... hydrogen peroxide multiple interactions ISO RGD:10511 6480464 AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EGFR protein] CTD PMID:14737115 hydrogen peroxide increases phosphorylation ISO RGD:10511 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:14737115 hydroxamic acid multiple interactions ISO RGD:10511 6480464 Hydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 hyperforin decreases phosphorylation ISO RGD:69152 6480464 hyperforin results in decreased phosphorylation of EGFR protein CTD PMID:32485087 hypochlorous acid multiple interactions ISO RGD:69152 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18156441 icariin multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein, [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 icariside II multiple interactions ISO RGD:69152 6480464 baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25119583 icariside II decreases phosphorylation ISO RGD:69152 6480464 baohuoside I results in decreased phosphorylation of EGFR protein CTD PMID:25119583 ICI-164384 multiple interactions ISO RGD:69152 6480464 ICI 164384 inhibits the reaction [[Estradiol co-treated with EGFR protein] results in increased expression of SIAH2 mRNA] CTD PMID:18629630 indole-3-methanol decreases expression ISO RGD:69152 6480464 indole-3-carbinol results in decreased expression of EGFR protein CTD PMID:18025290 indometacin increases expression ISO RGD:10511 6480464 Indomethacin results in increased expression of EGFR protein CTD PMID:17977527 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of EGFR mRNA CTD PMID:29523851 indometacin multiple interactions EXP 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA], Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 indometacin multiple interactions ISO RGD:10511 6480464 malabaricone B promotes the reaction [Indomethacin results in increased expression of EGFR protein], malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 inulin multiple interactions ISO RGD:10511 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of EGFR mRNA CTD PMID:36331819 irbesartan multiple interactions EXP 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 irinotecan multiple interactions ISO RGD:69152 6480464 bisindolylmaleimide I inhibits the reaction [Irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15723263 iron atom multiple interactions ISO RGD:69152 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 iron(0) multiple interactions ISO RGD:69152 6480464 [Arsenic co-treated with Iron] results in decreased expression of EGFR mRNA CTD PMID:31739468 isoflavones multiple interactions EXP 6480464 Isoflavones inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of EGFR mRNA] CTD PMID:34197824 isoprenaline increases expression ISO RGD:10511 6480464 Isoproterenol results in increased expression of EGFR mRNA CTD PMID:20003209 isoprenaline multiple interactions ISO RGD:69152 6480464 Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein] CTD PMID:18787115 isotretinoin decreases expression ISO RGD:69152 6480464 Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 ivermectin decreases expression ISO RGD:69152 6480464 Ivermectin results in decreased expression of EGFR protein CTD PMID:32959892 JTE-013 multiple interactions ISO RGD:69152 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of EGFR protein], JTE 013 inhibits the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:26518876 ketoconazole multiple interactions ISO RGD:69152 6480464 Ketoconazole inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of EGFR mRNA CTD PMID:37077353 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 KN-93 multiple interactions ISO RGD:69152 6480464 KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein] CTD PMID:32535744 L-ascorbic acid decreases expression ISO RGD:69152 6480464 Ascorbic Acid results in decreased expression of EGFR mRNA CTD PMID:21919647 L-methionine multiple interactions ISO RGD:10511 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of EGFR mRNA CTD PMID:33549593 lansoprazole increases expression ISO RGD:69152 6480464 Lansoprazole results in increased expression of EGFR protein CTD PMID:9881512 lapatinib decreases activity ISO RGD:69152 6480464 lapatinib results in decreased activity of EGFR protein CTD PMID:15665275 more ... lapatinib multiple interactions ISO RGD:69152 6480464 KRAS protein affects the reaction [EGFR protein affects the susceptibility to lapatinib] more ... CTD PMID:28739874 lapatinib affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to lapatinib CTD PMID:28739874 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of EGFR protein CTD PMID:17298174 lead diacetate increases phosphorylation ISO RGD:69152 6480464 lead acetate results in increased phosphorylation of EGFR protein CTD PMID:19133285 lead diacetate multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:19133285 lead nitrate multiple interactions ISO RGD:69152 6480464 EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone] more ... CTD PMID:20850495 lead nitrate increases phosphorylation ISO RGD:69152 6480464 lead nitrate results in increased phosphorylation of EGFR protein CTD PMID:20850495 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of EGFR protein CTD PMID:17298174 leflunomide increases expression ISO RGD:69152 6480464 leflunomide results in increased expression of EGFR mRNA CTD PMID:28988120 leflunomide multiple interactions ISO RGD:69152 6480464 Leflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 leukotriene C4 increases expression ISO RGD:10511 6480464 Leukotriene C4 results in increased expression of EGFR mRNA CTD PMID:12388339 linalool increases expression ISO RGD:69152 6480464 linalool results in increased expression of EGFR mRNA CTD PMID:19922762 linuron multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 linuron decreases expression EXP 6480464 Linuron results in decreased expression of EGFR mRNA CTD PMID:12730624 lipopolysaccharide increases phosphorylation ISO RGD:10511 6480464 Lipopolysaccharides results in increased phosphorylation of EGFR protein CTD PMID:21874253 , PMID:23099361 lipopolysaccharide multiple interactions ISO RGD:69152 6480464 [S-(1 more ... CTD PMID:35811015 lipopolysaccharide multiple interactions ISO RGD:10511 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein], TLR4 mutant form promotes the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:21874253 , PMID:23099361 lithium chloride increases expression ISO RGD:69152 6480464 Lithium Chloride results in increased expression of EGFR mRNA, Lithium Chloride results in increased expression of EGFR protein CTD PMID:22493441 lithium chloride multiple interactions ISO RGD:69152 6480464 [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA more ... CTD PMID:22493441 lovastatin multiple interactions ISO RGD:69152 6480464 Lovastatin inhibits the reaction [EGF protein promotes the reaction [EGFR protein results in increased phosphorylation of EGFR protein]], Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:12942316 , PMID:19760159 luteolin multiple interactions ISO RGD:69152 6480464 EGF protein inhibits the reaction [Luteolin results in decreased phosphorylation of EGFR protein] more ... CTD PMID:10556937 more ... luteolin decreases expression ISO RGD:69152 6480464 Luteolin results in decreased expression of EGFR mRNA CTD PMID:22926442 luteolin affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Luteolin CTD PMID:12168845 LY294002 multiple interactions ISO RGD:69152 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 magnesium dichloride multiple interactions ISO RGD:69152 6480464 [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 Malabaricone C multiple interactions ISO RGD:10511 6480464 malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 manganese(II) chloride increases activity ISO RGD:69152 6480464 manganese chloride results in increased activity of EGFR protein CTD PMID:2354210 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of EGFR mRNA CTD PMID:28801915 manganese(II) chloride multiple interactions ISO RGD:69152 6480464 [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 melittin increases activity ISO RGD:69152 6480464 Melitten results in increased activity of EGFR protein CTD PMID:22613720 menadione increases phosphorylation EXP 6480464 Vitamin K 3 results in increased phosphorylation of EGFR protein CTD PMID:15843167 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of EGFR mRNA CTD PMID:10901180 metamizole sodium multiple interactions EXP 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of EGFR mRNA CTD PMID:30467583 methidathion increases expression ISO RGD:10511 6480464 methidathion results in increased expression of EGFR mRNA CTD PMID:34813904 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of EGFR mRNA CTD PMID:30047161 methotrexate decreases response to substance ISO RGD:10511 6480464 EGFR mRNA results in decreased susceptibility to Methotrexate CTD PMID:16918715 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of EGFR mRNA CTD PMID:18803016 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of EGFR protein CTD PMID:8888411 methoxychlor increases phosphorylation ISO RGD:69152 6480464 Methoxychlor results in increased phosphorylation of EGFR protein CTD PMID:28426875 methoxychlor multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 Methylazoxymethanol acetate increases expression EXP 6480464 Methylazoxymethanol Acetate results in increased expression of EGFR mRNA CTD PMID:28349193 methylmercury chloride increases phosphorylation ISO RGD:69152 6480464 methylmercuric chloride results in increased phosphorylation of EGFR protein CTD PMID:28958600 methylmercury chloride increases expression ISO RGD:69152 6480464 methylmercuric chloride results in increased expression of EGFR mRNA CTD PMID:28001369 mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]] CTD PMID:20359552 microcystin-LR decreases methylation ISO RGD:69152 6480464 cyanoginosin LR results in decreased methylation of EGFR gene CTD PMID:29518473 microcystin-LR increases expression ISO RGD:69152 6480464 cyanoginosin LR results in increased expression of EGFR mRNA CTD PMID:29518473 mifepristone multiple interactions ISO RGD:69152 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]] more ... CTD PMID:10807665 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of EGFR mRNA CTD PMID:18591650 , PMID:25972201 MK-2206 increases expression ISO RGD:69152 6480464 MK 2206 results in increased expression of EGFR protein CTD PMID:27897231 MK-2206 multiple interactions ISO RGD:69152 6480464 platycodin D inhibits the reaction [MK 2206 results in increased expression of EGFR protein] CTD PMID:27897231 monosodium L-glutamate multiple interactions ISO RGD:10511 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of EGFR mRNA CTD PMID:19001666 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of EGFR mRNA CTD PMID:28954212 myo-inositol hexakisphosphate multiple interactions ISO RGD:69152 6480464 Phytic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 myricetin multiple interactions ISO RGD:10511 6480464 myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18995957 myricetin decreases phosphorylation ISO RGD:10511 6480464 myricetin results in decreased phosphorylation of EGFR protein CTD PMID:18995957 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:69152 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA] CTD PMID:22493441 N-acetyl-L-cysteine multiple interactions ISO RGD:10511 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15520183 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15849355 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:69152 6480464 Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] more ... CTD PMID:10640773 more ... N-acetylcysteamine decreases phosphorylation ISO RGD:69152 6480464 2-acetamidoethanethiol analog results in decreased phosphorylation of EGFR protein CTD PMID:20058253 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein CTD PMID:20332299 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:10511 6480464 Ethylnitrosourea results in increased mutagenesis of EGFR gene CTD PMID:15366372 , PMID:16724327 N-methyl-N'-nitro-N-nitrosoguanidine affects localization ISO RGD:69152 6480464 Methylnitronitrosoguanidine affects the localization of EGFR protein CTD PMID:15708576 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:69152 6480464 Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:15708576 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:22245120 , PMID:25164625 N-methylformamide decreases expression ISO RGD:10511 6480464 methylformamide analog results in decreased expression of EGFR mRNA, methylformamide results in decreased expression of EGFR mRNA CTD PMID:17040096 N-methylnicotinate multiple interactions ISO RGD:69152 6480464 trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:33148531 N-methylnicotinate decreases phosphorylation ISO RGD:69152 6480464 trigonelline results in decreased phosphorylation of EGFR protein CTD PMID:33148531 N-nitrosodiethylamine multiple interactions ISO RGD:10511 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA more ... CTD PMID:17942915 more ... N-nitrosodiethylamine increases expression ISO RGD:10511 6480464 Diethylnitrosamine results in increased expression of EGFR mRNA CTD PMID:27058323 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of EGFR mRNA, Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:15660382 , PMID:19638242 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:28943392 more ... N-nitrosodiethylamine decreases expression ISO RGD:10511 6480464 Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:20583210 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 naphthalene multiple interactions ISO RGD:10511 6480464 [gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene CTD PMID:20935109 naringin multiple interactions ISO RGD:69152 6480464 naringin inhibits the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22766066 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of EGFR mRNA CTD PMID:24136188 neocuproine multiple interactions ISO RGD:69152 6480464 [Copper binds to neocuproine] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 neratinib decreases activity ISO RGD:69152 6480464 neratinib results in decreased activity of EGFR protein, neratinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 , PMID:22242139 nevirapine decreases expression ISO RGD:69152 6480464 Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of EGFR mRNA CTD PMID:22546817 nickel dichloride increases expression ISO RGD:69152 6480464 nickel chloride results in increased expression of EGFR protein CTD PMID:26026961 nickel dichloride multiple interactions ISO RGD:69152 6480464 RECK protein inhibits the reaction [nickel chloride results in increased expression of EGFR protein] CTD PMID:26026961 nickel subsulfide increases expression EXP 6480464 nickel subsulfide results in increased expression of EGFR mRNA CTD PMID:21086188 nickel sulfate multiple interactions ISO RGD:10511 6480464 [TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate CTD PMID:19131640 niclosamide decreases expression ISO RGD:69152 6480464 Niclosamide analog results in decreased expression of EGFR protein more ... CTD PMID:28284560 , PMID:30779072 niclosamide decreases phosphorylation ISO RGD:69152 6480464 Niclosamide results in decreased phosphorylation of EGFR protein CTD PMID:28426875 nicotine increases phosphorylation ISO RGD:69152 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 nicotine multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 nobiletin multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein, [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 O-methyleugenol decreases expression ISO RGD:10511 6480464 methyleugenol results in decreased expression of EGFR protein CTD PMID:15618236 ochratoxin A increases phosphorylation ISO RGD:10511 6480464 ochratoxin A results in increased phosphorylation of EGFR protein CTD PMID:23172667 oleic acid increases phosphorylation ISO RGD:69152 6480464 Oleic Acid results in increased phosphorylation of EGFR protein CTD PMID:27447558 oleic acid multiple interactions ISO RGD:69152 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 omipalisib multiple interactions ISO RGD:69152 6480464 omipalisib inhibits the reaction [RHPN1-AS1 protein results in increased expression of EGFR protein] CTD PMID:36125241 oridonin multiple interactions ISO RGD:69152 6480464 oridonin analog inhibits the reaction [EGF protein promotes the reaction [EGFR protein modified form binds to STAT3 protein]], oridonin analog inhibits the reaction [EGFR protein results in increased phosphorylation of STAT3 protein] CTD PMID:31594861 osimertinib multiple interactions ISO RGD:69152 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:30145802 more ... osimertinib decreases phosphorylation ISO RGD:69152 151357000 osimertinib decreases phosphorylation of EGFR protein in lung RGD osimertinib decreases phosphorylation ISO RGD:10511 6480464 osimertinib results in decreased phosphorylation of EGFR protein CTD PMID:35970427 osimertinib decreases activity ISO RGD:69152 6480464 osimertinib results in decreased activity of EGFR protein CTD PMID:28237877 ouabain decreases phosphorylation ISO RGD:69152 6480464 Ouabain results in decreased phosphorylation of EGFR protein CTD PMID:28795476 oxaliplatin multiple interactions ISO RGD:69152 6480464 [gefitinib co-treated with oxaliplatin] results in decreased phosphorylation of EGFR protein, EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:13680161 , PMID:16098254 oxaliplatin increases phosphorylation ISO RGD:69152 6480464 oxaliplatin results in increased phosphorylation of EGFR protein CTD PMID:16243822 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 oxazepam decreases expression ISO RGD:10511 6480464 Oxazepam results in decreased expression of EGFR mRNA, Oxazepam results in decreased expression of EGFR protein CTD PMID:15618236 oxytocin increases expression EXP 6480464 Oxytocin results in increased expression of EGFR protein modified form CTD PMID:23707249 ozone multiple interactions ISO RGD:69152 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of EGFR mRNA more ... CTD PMID:19536146 more ... ozone increases phosphorylation ISO RGD:10511 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:26464147 ozone multiple interactions ISO RGD:10511 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:26464147 , PMID:34911549 ozone increases phosphorylation ISO RGD:69152 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:19536146 , PMID:25303742 p-chloromercuribenzoic acid decreases expression ISO RGD:69152 6480464 p-Chloromercuribenzoic Acid results in decreased expression of EGFR mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGFR mRNA CTD PMID:27188386 p-tert-Amylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 p-tert-Amylphenol increases phosphorylation ISO RGD:69152 6480464 4-tert-octylphenol results in increased phosphorylation of EGFR protein CTD PMID:32466334 paclitaxel increases phosphorylation ISO RGD:69152 6480464 Paclitaxel results in increased phosphorylation of EGFR protein CTD PMID:16211241 , PMID:20726858 paclitaxel decreases expression ISO RGD:69152 6480464 Paclitaxel results in decreased expression of EGFR mRNA CTD PMID:18058816 paclitaxel multiple interactions ISO RGD:69152 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein, Paclitaxel promotes the reaction [HER3 protein binds to EGFR protein] CTD PMID:16413505 , PMID:20726858 Paeonol multiple interactions EXP 6480464 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein, [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 pamidronate multiple interactions ISO RGD:69152 6480464 [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein], Pamidronate promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:32337366 paracetamol multiple interactions ISO RGD:10511 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein more ... CTD PMID:17585979 , PMID:28123000 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EGFR mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:69152 6480464 Acetaminophen results in increased expression of EGFR mRNA CTD PMID:29067470 paracetamol multiple interactions ISO RGD:69152 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 paracetamol affects localization ISO RGD:10511 6480464 Acetaminophen affects the localization of EGFR protein CTD PMID:28123000 paracetamol decreases expression ISO RGD:69152 6480464 Acetaminophen results in decreased expression of EGFR mRNA CTD PMID:21420995 paracetamol decreases expression ISO RGD:10511 6480464 Acetaminophen results in decreased expression of EGFR mRNA, Acetaminophen results in decreased expression of EGFR protein CTD PMID:15618236 , PMID:24126418 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of EGFR protein CTD PMID:17298174 parathion multiple interactions ISO RGD:69152 6480464 [Parathion co-treated with Estradiol] results in increased expression of EGFR protein, Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 , PMID:17622325 parathion increases expression ISO RGD:69152 6480464 Parathion results in increased expression of EGFR protein CTD PMID:17390078 , PMID:17622325 paroxetine multiple interactions ISO RGD:10511 6480464 [[Paroxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:19662385 PD 168393 multiple interactions ISO RGD:69152 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein more ... CTD PMID:16413505 more ... PD 168393 multiple interactions EXP 6480464 PD168393 inhibits the reaction [AGT protein results in increased phosphorylation of EGFR protein] CTD PMID:25398788 PD 168393 affects localization ISO RGD:69152 6480464 PD168393 affects the localization of EGFR protein, PD168393 affects the localization of EGFR protein modified form CTD PMID:21967610 PD 168393 decreases phosphorylation ISO RGD:69152 6480464 PD168393 results in decreased phosphorylation of EGFR protein CTD PMID:21967610 , PMID:23527233 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of EGFR mRNA CTD PMID:25710175 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of EGFR mRNA, perfluorooctane sulfonic acid results in increased expression of EGFR protein CTD PMID:21251948 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:10511 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EGFR mRNA more ... CTD PMID:36331819 perfluorooctane-1-sulfonic acid increases phosphorylation ISO RGD:10511 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of EGFR protein CTD PMID:28288859 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of EGFR mRNA CTD PMID:16221955 perfluorooctanoic acid decreases expression ISO RGD:10511 6480464 perfluorooctanoic acid results in decreased expression of EGFR protein CTD PMID:22414604 perfluorooctanoic acid multiple interactions ISO RGD:10511 6480464 Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein] more ... CTD PMID:22414604 perfluorooctanoic acid increases expression ISO RGD:10511 6480464 perfluorooctanoic acid results in increased expression of EGFR protein CTD PMID:20118188 PHA-665752 decreases phosphorylation ISO RGD:69152 6480464 5-((2 more ... CTD PMID:21266357 PHA-665752 multiple interactions ISO RGD:69152 6480464 [5-((2 more ... CTD PMID:21266357 phenobarbital multiple interactions ISO RGD:10511 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of EGFR mRNA], Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:19482888 , PMID:6309801 phenobarbital multiple interactions ISO RGD:69152 6480464 Phenobarbital inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 , PMID:30364229 phenobarbital affects expression ISO RGD:10511 6480464 Phenobarbital affects the expression of EGFR mRNA CTD PMID:19136022 , PMID:23091169 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19162173 phenobarbital decreases expression ISO RGD:10511 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19482888 phenobarbital multiple interactions EXP 6480464 Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:10828207 phenylarsine oxide multiple interactions ISO RGD:10511 6480464 oxophenylarsine inhibits the reaction [EGF protein binds to and affects the localization of EGFR protein] CTD PMID:12093727 phenylephrine multiple interactions ISO RGD:10511 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein], Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18360054 phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of EGFR protein CTD PMID:14676212 phenylephrine multiple interactions EXP 6480464 [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein], [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] CTD PMID:16760267 phenylmercury acetate increases expression ISO RGD:69152 6480464 Phenylmercuric Acetate results in increased expression of EGFR mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of EGFR mRNA CTD PMID:8603490 phloretin multiple interactions ISO RGD:69152 6480464 [Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein CTD PMID:34896434 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10511 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 more ... phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA CTD PMID:10516208 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:10511 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein CTD PMID:26513295 phorbol 13-acetate 12-myristate increases expression ISO RGD:10511 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR CTD PMID:26100520 phorbol 13-acetate 12-myristate increases expression ISO RGD:69152 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR protein CTD PMID:19447859 , PMID:25866363 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:69152 6480464 naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein], pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 , PMID:25866363 phorone multiple interactions ISO RGD:10511 6480464 [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 phosphoramidon multiple interactions ISO RGD:69152 6480464 phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 Phytolaccoside E increases expression ISO RGD:69152 6480464 esculentoside A results in increased expression of EGFR protein CTD PMID:36460195 piperonyl butoxide multiple interactions ISO RGD:10511 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA CTD PMID:20101389 pirfenidone multiple interactions ISO RGD:69152 6480464 [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein more ... CTD PMID:28739874 pirinixic acid affects expression ISO RGD:10511 6480464 pirinixic acid affects the expression of EGFR mRNA CTD PMID:19136022 pirinixic acid decreases expression ISO RGD:10511 6480464 pirinixic acid results in decreased expression of EGFR mRNA CTD PMID:11798191 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of EGFR protein CTD PMID:2404574 pirinixic acid multiple interactions ISO RGD:10511 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of EGFR mRNA more ... CTD PMID:19710929 more ... piroxicam decreases expression ISO RGD:69152 6480464 Piroxicam results in decreased expression of EGFR mRNA CTD PMID:21858171 piroxicam multiple interactions EXP 6480464 Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 platycodin D decreases expression ISO RGD:69152 6480464 platycodin D results in decreased expression of EGFR protein CTD PMID:23867902 more ... platycodin D multiple interactions ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein] more ... CTD PMID:27897231 , PMID:28711525 ponatinib decreases activity ISO RGD:69152 6480464 ponatinib results in decreased activity of EGFR protein mutant form CTD PMID:19878872 potassium chromate decreases expression ISO RGD:69152 6480464 potassium chromate(VI) results in decreased expression of EGFR mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:69152 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA, [potassium chromate(VI) results in increased abundance of Chromates] which results in increased phosphorylation of EGFR protein CTD PMID:22079256 , PMID:32006662 primaquine multiple interactions ISO RGD:69152 6480464 Primaquine inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 prochloraz multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 procymidone multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 progesterone multiple interactions ISO RGD:69152 6480464 [Progesterone co-treated with Estradiol] results in increased expression of EGFR mRNA more ... CTD PMID:16175315 more ... progesterone multiple interactions EXP 6480464 [Estrogens co-treated with Progesterone] results in increased expression of EGFR mRNA, [Estrogens co-treated with Progesterone] results in increased expression of EGFR protein CTD PMID:21258428 progesterone increases expression EXP 6480464 Progesterone results in increased expression of EGFR mRNA CTD PMID:18591650 progesterone multiple interactions ISO RGD:10511 6480464 Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]] more ... CTD PMID:22414604 progesterone increases expression ISO RGD:69152 6480464 Progesterone results in increased expression of EGFR protein CTD PMID:16175315 propofol multiple interactions ISO RGD:69152 6480464 [Propofol results in increased susceptibility to STA 9090] which results in decreased expression of EGFR protein CTD PMID:24784839 propranolol multiple interactions ISO RGD:69152 6480464 Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18787115 prostaglandin E2 increases secretion ISO RGD:69152 6480464 EGFR protein results in increased secretion of Dinoprostone CTD PMID:16213893 prostaglandin E2 increases expression ISO RGD:69152 6480464 Dinoprostone results in increased expression of EGFR protein modified form CTD PMID:30208247 prostaglandin E2 multiple interactions ISO RGD:69152 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in increased expression of EGFR protein modified form] more ... CTD PMID:20850495 , PMID:30208247 prostaglandin E2 increases phosphorylation ISO RGD:69152 6480464 Dinoprostone results in increased phosphorylation of EGFR protein CTD PMID:17805209 protein kinase inhibitor multiple interactions ISO RGD:69152 6480464 Protein Kinase Inhibitors inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein] CTD PMID:25303742 protoporphyrin decreases expression ISO RGD:69152 6480464 protoporphyrin IX results in decreased expression of EGFR protein CTD PMID:23624237 Ptaquiloside decreases expression ISO RGD:10511 6480464 ptaquiloside results in decreased expression of EGFR mRNA CTD PMID:23274088 pterostilbene multiple interactions ISO RGD:69152 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 purpurin decreases expression ISO RGD:69152 6480464 purpurin results in decreased expression of EGFR protein CTD PMID:33368780 pyocyanine increases phosphorylation ISO RGD:69152 6480464 Pyocyanine results in increased phosphorylation of EGFR protein CTD PMID:24015256 pyrrolidine dithiocarbamate multiple interactions ISO RGD:69152 6480464 [Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 quercetin affects response to substance ISO RGD:69152 6480464 EGFR protein affects the susceptibility to Quercetin CTD PMID:12168845 quercetin multiple interactions ISO RGD:10511 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:23099361 quercetin decreases phosphorylation ISO RGD:69152 6480464 Quercetin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 more ... quercetin decreases expression ISO RGD:69152 6480464 Quercetin results in decreased expression of EGFR mRNA CTD PMID:21308698 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:25164625 quercetin multiple interactions ISO RGD:69152 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of EGFR mRNA more ... CTD PMID:10556937 more ... quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO RGD:69152 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO RGD:69152 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quinazolines decreases phosphorylation ISO RGD:69152 6480464 Quinazolines analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 quinazolines multiple interactions ISO RGD:69152 6480464 Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK1 protein], Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK3 protein] CTD PMID:21075094 quinolin-8-ol multiple interactions ISO RGD:69152 6480464 [Copper binds to Oxyquinoline] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 rac-lactic acid decreases expression ISO RGD:69152 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 raloxifene multiple interactions ISO RGD:69152 6480464 [Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein, Raloxifene Hydrochloride results in decreased expression of and affects the localization of EGFR protein CTD PMID:18371987 , PMID:23842642 raloxifene decreases phosphorylation ISO RGD:69152 6480464 Raloxifene Hydrochloride results in decreased phosphorylation of EGFR protein CTD PMID:23842642 raloxifene increases phosphorylation EXP 6480464 Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein CTD PMID:24782323 ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 reactive oxygen species multiple interactions ISO RGD:10511 6480464 [[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein] more ... CTD PMID:23376140 reactive oxygen species multiple interactions EXP 6480464 EGFR protein affects the reaction [Reactive Oxygen Species affects the phosphorylation of SHC1 protein] CTD PMID:19168439 resveratrol multiple interactions ISO RGD:69152 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of EGFR mRNA more ... CTD PMID:16343977 more ... resveratrol decreases expression ISO RGD:10511 6480464 resveratrol results in decreased expression of EGFR mRNA CTD PMID:23525482 resveratrol decreases phosphorylation ISO RGD:69152 6480464 resveratrol results in decreased phosphorylation of EGFR protein CTD PMID:20729295 , PMID:23527233 resveratrol increases activity ISO RGD:69152 6480464 resveratrol results in increased activity of EGFR protein CTD PMID:15802018 resveratrol increases phosphorylation ISO RGD:69152 6480464 resveratrol results in increased phosphorylation of EGFR protein CTD PMID:23527233 resveratrol affects localization ISO RGD:69152 6480464 resveratrol affects the localization of EGFR protein, resveratrol affects the localization of EGFR protein modified form CTD PMID:23527233 resveratrol increases degradation ISO RGD:69152 6480464 resveratrol results in increased degradation of EGFR protein CTD PMID:23527233 resveratrol multiple interactions ISO RGD:10511 6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR] more ... CTD PMID:26100520 resveratrol decreases expression ISO RGD:69152 6480464 resveratrol results in decreased expression of EGFR mRNA, resveratrol results in decreased expression of EGFR protein CTD PMID:24514079 , PMID:25667456 resveratrol affects binding ISO RGD:69152 6480464 resveratrol binds to EGFR protein CTD PMID:20729295 romidepsin decreases expression ISO RGD:69152 6480464 romidepsin results in decreased expression of EGFR protein CTD PMID:15014036 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of EGFR mRNA, Rotenone results in decreased expression of EGFR protein CTD PMID:17555550 , PMID:28374803 rottlerin multiple interactions ISO RGD:69152 6480464 rottlerin inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15177934 , PMID:15723263 ruthenium atom multiple interactions ISO RGD:69152 6480464 [Ruthenium binds to Phloretin] which results in decreased expression of EGFR protein CTD PMID:34896434 rutin multiple interactions ISO RGD:69152 6480464 Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:69152 6480464 [S-(1 more ... CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO RGD:69152 6480464 S-(1, 2-dichlorovinyl)cysteine results in decreased expression of EGFR mRNA CTD PMID:35811015 SB 431542 multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 scopolamine decreases expression EXP 6480464 Scopolamine results in decreased expression of EGFR mRNA CTD PMID:12818353 selenium atom decreases expression ISO RGD:69152 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 selenomethionine increases expression ISO RGD:69152 6480464 Selenomethionine results in increased expression of EGFR mRNA CTD PMID:17205524 senecionine decreases expression ISO RGD:10511 6480464 senecionine results in decreased expression of EGFR protein CTD PMID:35357534 sepantronium multiple interactions ISO RGD:69152 6480464 EGF protein inhibits the reaction [sepantronium results in decreased phosphorylation of EGFR protein] CTD PMID:28787001 sepantronium decreases phosphorylation ISO RGD:69152 6480464 sepantronium results in decreased phosphorylation of EGFR protein CTD PMID:28787001 serpentine asbestos decreases phosphorylation ISO RGD:69152 6480464 Asbestos, Serpentine results in decreased phosphorylation of EGFR protein CTD PMID:15626777 serpentine asbestos multiple interactions ISO RGD:10511 6480464 N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos, Serpentine results in increased activity of EGFR protein] CTD PMID:16571779 serpentine asbestos increases activity ISO RGD:10511 6480464 Asbestos, Serpentine results in increased activity of EGFR protein CTD PMID:16571779 sertraline increases expression ISO RGD:69152 6480464 Sertraline results in increased expression of EGFR mRNA CTD PMID:24865413 silicon dioxide increases expression ISO RGD:69152 6480464 Silicon Dioxide analog results in increased expression of EGFR mRNA, Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:21540303 more ... silicon dioxide increases phosphorylation ISO RGD:69152 6480464 Silicon Dioxide analog results in increased phosphorylation of EGFR protein CTD PMID:24844442 silicon dioxide increases expression ISO RGD:10511 6480464 Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:23221170 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]], Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 sirolimus multiple interactions ISO RGD:10511 6480464 [Sirolimus results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of MAPK1 protein more ... CTD PMID:19151764 sirolimus multiple interactions ISO RGD:69152 6480464 AG 1879 inhibits the reaction [Sirolimus results in increased phosphorylation of EGFR protein] CTD PMID:19151764 sodium arsenate increases expression ISO RGD:10511 6480464 sodium arsenate results in increased expression of EGFR mRNA CTD PMID:21795629 sodium arsenite multiple interactions ISO RGD:69152 6480464 [sodium arsenite results in increased expression of EGFR protein] which results in increased phosphorylation of PCNA protein more ... CTD PMID:11723127 more ... sodium arsenite decreases phosphorylation EXP 6480464 sodium arsenite results in decreased phosphorylation of EGFR protein CTD PMID:29228391 sodium arsenite decreases expression ISO RGD:69152 6480464 sodium arsenite results in decreased expression of EGFR mRNA CTD PMID:28595984 sodium arsenite affects methylation ISO RGD:69152 6480464 sodium arsenite affects the methylation of EGFR gene CTD PMID:28589171 sodium arsenite increases activity ISO RGD:69152 6480464 sodium arsenite results in increased activity of EGFR protein CTD PMID:19414066 sodium arsenite increases expression ISO RGD:69152 6480464 sodium arsenite results in increased expression of EGFR mRNA, sodium arsenite results in increased expression of EGFR protein CTD PMID:12016162 , PMID:25907674 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:9710602 sodium arsenite multiple interactions EXP 6480464 [EGF protein results in decreased expression of EGFR protein] inhibits the reaction [sodium arsenite results in increased activity of MAPK1 protein] more ... CTD PMID:29228391 , PMID:9710602 sodium arsenite increases expression ISO RGD:10511 6480464 sodium arsenite results in increased expression of EGFR mRNA CTD PMID:17077188 , PMID:9846968 sodium arsenite multiple interactions ISO RGD:10511 6480464 sodium arsenite promotes the reaction [SRC protein binds to EGFR protein], sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:11723127 sodium arsenite decreases expression ISO RGD:10511 6480464 sodium arsenite results in decreased expression of EGFR mRNA, sodium arsenite results in decreased expression of EGFR protein CTD PMID:16507464 , PMID:19822182 sodium arsenite increases phosphorylation ISO RGD:69152 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:10564177 more ... sodium arsenite affects expression ISO RGD:10511 6480464 sodium arsenite affects the expression of EGFR mRNA CTD PMID:16507464 sodium chloride increases phosphorylation ISO RGD:10511 6480464 Sodium Chloride results in increased phosphorylation of EGFR protein CTD PMID:21568938 sodium chloride multiple interactions ISO RGD:10511 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] more ... CTD PMID:21568938 sodium hydroxide affects response to substance ISO RGD:69152 6480464 EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 sorafenib decreases expression ISO RGD:69152 6480464 sorafenib results in decreased expression of EGFR mRNA CTD PMID:26409325 sotorasib increases phosphorylation ISO RGD:69152 6480464 sotorasib results in increased phosphorylation of EGFR protein CTD PMID:31666701 sphingosine 1-phosphate multiple interactions ISO RGD:69152 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of EGFR protein] CTD PMID:26518876 sphingosine 1-phosphate increases phosphorylation ISO RGD:69152 6480464 sphingosine 1-phosphate results in increased phosphorylation of EGFR protein CTD PMID:26518876 staurosporine multiple interactions ISO RGD:69152 6480464 Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 stilbenoid multiple interactions ISO RGD:69152 6480464 Stilbenes analog results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:25063218 SU6656 multiple interactions ISO RGD:69152 6480464 SU 6656 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15504454 SU6656 multiple interactions ISO RGD:10511 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein], [SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:23376140 succimer multiple interactions ISO RGD:69152 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of EGFR mRNA CTD PMID:26378955 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of EGFR mRNA CTD PMID:30047161 sulfasalazine multiple interactions ISO RGD:69152 6480464 [Sulfasalazine co-treated with celastrol] affects the expression of EGFR protein more ... CTD PMID:20007406 sulfasalazine decreases expression ISO RGD:10511 6480464 Sulfasalazine results in decreased expression of EGFR mRNA, Sulfasalazine results in decreased expression of EGFR protein CTD PMID:31830553 sulindac sulfide multiple interactions ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein], Chloroquine inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfide decreases expression ISO RGD:69152 6480464 sulindac sulfide results in decreased expression of EGFR protein CTD PMID:20332299 sulindac sulfide increases ubiquitination ISO RGD:69152 6480464 sulindac sulfide results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfide increases phosphorylation ISO RGD:69152 6480464 sulindac sulfide results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfide decreases phosphorylation ISO RGD:69152 6480464 sulindac sulfide results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions ISO RGD:69152 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein], Chloroquine inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfone increases ubiquitination ISO RGD:69152 6480464 sulindac sulfone results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions EXP 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein, [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein modified form CTD PMID:17908994 sulindac sulfone increases phosphorylation ISO RGD:69152 6480464 sulindac sulfone results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases phosphorylation ISO RGD:69152 6480464 sulindac sulfone results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases expression ISO RGD:69152 6480464 sulindac sulfone results in decreased expression of EGFR protein CTD PMID:20332299 Sulpyrine multiple interactions EXP 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 sunitinib decreases expression ISO RGD:69152 6480464 Sunitinib results in decreased expression of EGFR mRNA CTD PMID:31533062 suramin multiple interactions EXP 6480464 Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of EGFR protein] CTD PMID:9710602 taiwanin C decreases phosphorylation ISO RGD:10511 6480464 taiwanin C results in decreased phosphorylation of EGFR protein CTD PMID:26537528 , PMID:30884126 tamoxifen decreases response to substance ISO RGD:69152 6480464 EGFR protein results in decreased susceptibility to Tamoxifen CTD PMID:15665275 , PMID:16000581 tamoxifen affects expression ISO RGD:10511 6480464 Tamoxifen affects the expression of EGFR mRNA CTD PMID:17555576 tamoxifen increases expression ISO RGD:69152 6480464 Tamoxifen results in increased expression of EGFR mRNA, Tamoxifen results in increased expression of EGFR protein CTD PMID:20005069 tamoxifen multiple interactions ISO RGD:69152 6480464 [EGF protein results in increased activity of EGFR protein] which results in decreased susceptibility to Tamoxifen more ... CTD PMID:19347870 , PMID:24758408 tanespimycin decreases expression ISO RGD:69152 6480464 tanespimycin analog results in decreased expression of EGFR protein, tanespimycin results in decreased expression of EGFR protein CTD PMID:17010675 more ... tanespimycin multiple interactions ISO RGD:69152 6480464 tanespimycin results in increased degradation of and results in decreased expression of EGFR protein CTD PMID:16061882 taurocholic acid increases phosphorylation ISO RGD:69152 6480464 Taurocholic Acid results in increased phosphorylation of EGFR protein CTD PMID:26518876 taurocholic acid multiple interactions ISO RGD:69152 6480464 JTE 013 inhibits the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein], S1PR2 mRNA promotes the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:26518876 tephrosin affects localization ISO RGD:69152 6480464 tephrosin affects the localization of EGFR protein CTD PMID:20056314 tephrosin multiple interactions ISO RGD:69152 6480464 Chloroquine inhibits the reaction [tephrosin results in increased degradation of EGFR protein] more ... CTD PMID:20056314 Terfenadine multiple interactions ISO RGD:69152 6480464 11 more ... CTD PMID:19289568 Terfenadine decreases phosphorylation ISO RGD:69152 6480464 Terfenadine analog results in decreased phosphorylation of EGFR protein CTD PMID:19289568 teriflunomide multiple interactions ISO RGD:69152 6480464 teriflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 tert-butyl hydroperoxide multiple interactions ISO RGD:69152 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA, MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA] CTD PMID:35690295 testosterone multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:17272394 more ... testosterone increases phosphorylation EXP 6480464 Testosterone results in increased phosphorylation of EGFR protein CTD PMID:21177760 testosterone increases expression ISO RGD:69152 6480464 Testosterone results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone multiple interactions ISO RGD:69152 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone increases expression ISO RGD:10511 6480464 Testosterone deficiency results in increased expression of EGFR mRNA, Testosterone results in increased expression of EGFR mRNA CTD PMID:21669218 , PMID:33848595 Tetrachlorobisphenol A multiple interactions ISO RGD:69152 6480464 4-(6-bromo-1 more ... CTD PMID:36190352 Tetrachlorobisphenol A increases expression ISO RGD:69152 6480464 tetrachlorodian results in increased expression of EGFR mRNA CTD PMID:33582643 , PMID:36190352 tetrachloromethane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:18006644 , PMID:29923357 tetrachloromethane decreases expression ISO RGD:10511 6480464 Carbon Tetrachloride results in decreased expression of EGFR mRNA CTD PMID:29987408 tetrachloromethane increases expression ISO RGD:10511 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA, Carbon Tetrachloride results in increased expression of EGFR protein CTD PMID:17484886 , PMID:27477297 tetrachloromethane multiple interactions ISO RGD:10511 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA CTD PMID:16644059 , PMID:18006644 tetracycline decreases expression ISO RGD:10511 6480464 Tetracycline results in decreased expression of EGFR mRNA CTD PMID:24489787 tetramethylpyrazine multiple interactions ISO RGD:10511 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetraphene multiple interactions ISO RGD:10511 6480464 AHR protein affects the reaction [benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein]], benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 tetrathiomolybdate(2-) multiple interactions ISO RGD:69152 6480464 tetrathiomolybdate inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18480265 thapsigargin increases expression ISO RGD:10511 6480464 Thapsigargin results in increased expression of EGFR protein CTD PMID:24648495 theaflavin multiple interactions ISO RGD:10511 6480464 theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of EGFR mRNA CTD PMID:23411599 , PMID:34492290 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EGFR mRNA CTD PMID:28943392 toluene 2,4-diisocyanate multiple interactions ISO RGD:69152 6480464 EGFR protein affects the reaction [[Toluene 2 more ... CTD PMID:16908450 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 topotecan decreases expression ISO RGD:10511 6480464 Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 topotecan multiple interactions ISO RGD:69152 6480464 [RTKI cpd results in decreased activity of EGFR protein] which results in decreased susceptibility to Topotecan CTD PMID:15923621 topotecan decreases phosphorylation ISO RGD:69152 6480464 Topotecan results in decreased phosphorylation of EGFR protein CTD PMID:15923621 topotecan decreases expression ISO RGD:69152 6480464 Topotecan results in decreased expression of EGFR mRNA, Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 torin 1 multiple interactions ISO RGD:69152 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 more ... CTD PMID:26455392 trans-piceid multiple interactions ISO RGD:69152 6480464 polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 triamterene affects response to substance ISO RGD:69152 6480464 EGFR gene SNP affects the susceptibility to Triamterene CTD PMID:25622337 trichloroethene decreases expression ISO RGD:10511 6480464 Trichloroethylene results in decreased expression of EGFR mRNA CTD PMID:15363585 more ... trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of EGFR gene CTD PMID:27618143 trichostatin A increases expression ISO RGD:69152 6480464 trichostatin A results in increased expression of EGFR mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of EGFR mRNA CTD PMID:30589522 triphenyl phosphate increases expression ISO RGD:69152 6480464 triphenyl phosphate results in increased expression of EGFR mRNA CTD PMID:35776891 Triptolide decreases expression ISO RGD:10511 6480464 triptolide results in decreased expression of EGFR mRNA CTD PMID:32835833 troglitazone multiple interactions ISO RGD:69152 6480464 [Troglitazone co-treated with 4-((3-bromophenyl)amino)-6, 7-dimethoxyquinazoline] results in decreased expression of EGFR protein CTD PMID:32822399 troglitazone affects expression ISO RGD:69152 6480464 Troglitazone affects the expression of EGFR mRNA CTD PMID:32822399 troglitazone decreases expression ISO RGD:69152 6480464 Troglitazone results in decreased expression of EGFR protein CTD PMID:32822399 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:69152 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 trovafloxacin multiple interactions ISO RGD:10511 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EGFR mRNA CTD PMID:18930950 tyrphostin AG 1478 multiple interactions ISO RGD:69152 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] more ... CTD PMID:15177934 more ... tyrphostin AG 1478 decreases expression ISO RGD:69152 6480464 RTKI cpd results in decreased expression of EGFR protein modified form CTD PMID:29974605 tyrphostin AG 1478 decreases phosphorylation ISO RGD:69152 6480464 RTKI cpd results in decreased phosphorylation of EGFR protein CTD PMID:15923621 more ... tyrphostin AG 1478 decreases activity ISO RGD:69152 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:27071941 tyrphostin AG 1478 decreases activity EXP 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:15574683 tyrphostin AG 1478 multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] more ... CTD PMID:15459120 more ... tyrphostin AG 1478 decreases activity ISO RGD:10511 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:12794006 tyrphostin AG 1478 multiple interactions ISO RGD:10511 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:18758753 more ... U-73122 multiple interactions ISO RGD:69152 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:15177934 urethane multiple interactions ISO RGD:10511 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of EGFR mRNA, IFNG protein promotes the reaction [Urethane results in increased expression of EGFR mRNA] CTD PMID:12400877 , PMID:12810352 urethane decreases expression ISO RGD:69152 6480464 Urethane results in decreased expression of EGFR mRNA CTD PMID:28818685 urethane increases expression ISO RGD:10511 6480464 Urethane results in increased expression of EGFR mRNA CTD PMID:12400877 ursodeoxycholic acid multiple interactions ISO RGD:69152 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:14747693 ursolic acid multiple interactions ISO RGD:10511 6480464 resveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] more ... CTD PMID:26100520 UTP increases phosphorylation EXP 6480464 Uridine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:14676212 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of EGFR mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:69152 6480464 Valproic Acid results in decreased methylation of EGFR gene CTD PMID:29154799 valproic acid multiple interactions ISO RGD:69152 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:69152 6480464 Valproic Acid results in increased expression of EGFR mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:10511 6480464 Valproic Acid results in decreased expression of EGFR mRNA CTD PMID:24535564 vanadyl sulfate increases phosphorylation ISO RGD:69152 6480464 vanadyl sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 , PMID:11943669 vandetanib affects response to substance ISO RGD:69152 6480464 EGFR affects the susceptibility to vandetanib CTD PMID:15604279 vandetanib decreases activity ISO RGD:69152 6480464 vandetanib results in decreased activity of EGFR protein CTD PMID:15596048 vandetanib decreases phosphorylation ISO RGD:69152 6480464 vandetanib results in decreased phosphorylation of EGFR protein CTD PMID:21350000 veliparib decreases response to substance ISO RGD:69152 6480464 EGFR protein results in decreased susceptibility to veliparib CTD PMID:21912620 veliparib affects localization ISO RGD:69152 6480464 veliparib affects the localization of EGFR protein CTD PMID:21719137 vinclozolin multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of EGFR gene CTD PMID:31682807 vitamin E decreases expression ISO RGD:69152 6480464 Vitamin E results in decreased expression of EGFR mRNA CTD PMID:19244175 vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of EGFR mRNA, vorinostat results in decreased expression of EGFR protein CTD PMID:21389970 vorinostat decreases phosphorylation ISO RGD:69152 6480464 vorinostat results in decreased phosphorylation of EGFR protein CTD PMID:20531243 WIN 55212-2 multiple interactions ISO RGD:69152 6480464 RTKI cpd inhibits the reaction [(3R)-((2 more ... CTD PMID:20619260 WIN 55212-2 increases phosphorylation ISO RGD:69152 6480464 (3R)-((2 more ... CTD PMID:20619260 wortmannin multiple interactions ISO RGD:69152 6480464 Wortmannin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:15177934 more ... wortmannin multiple interactions ISO RGD:10511 6480464 wortmannin inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:21568938 zinc atom multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc atom increases phosphorylation ISO RGD:10511 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694 zinc atom increases phosphorylation ISO RGD:69152 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc atom multiple interactions ISO RGD:10511 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 , PMID:33549593 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc dichloride increases phosphorylation ISO RGD:69152 6480464 zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 zinc sulfate multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16410015 zinc sulfate increases phosphorylation EXP 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:19946718 zinc sulfate increases phosphorylation ISO RGD:69152 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 , PMID:11943669 zinc(0) multiple interactions ISO RGD:69152 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc(0) multiple interactions ISO RGD:10511 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 , PMID:33549593 zinc(0) increases phosphorylation ISO RGD:69152 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc(0) increases phosphorylation ISO RGD:10511 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694
