Upp1 (uridine phosphorylase 1) - Rat Genome Database

Name: Upp1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Upp1 (uridine phosphorylase 1) Rattus norvegicus

Analyze

Symbol:

Upp1

Name:

uridine phosphorylase 1

RGD ID:

1305566

Description:

Predicted to enable identical protein binding activity and pentosyltransferase activity. Involved in cellular response to glucose starvation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Biomarker of middle cerebral artery infarction. Orthologous to human UPP1 (uridine phosphorylase 1); PARTICIPATES IN pyrimidine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC289801; MGC124655

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UPP1 (uridine phosphorylase 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Upp1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Upp1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UPP1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UPP1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Upp1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UPP1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UPP1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Upp1 (uridine phosphorylase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	UPP2 (uridine phosphorylase 2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	UPP1 (uridine phosphorylase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Upp1 (uridine phosphorylase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	upp1 (uridine phosphorylase 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	upp-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3788	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6330	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	83,809,495 - 83,829,299 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	83,809,960 - 83,829,462 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	88,205,103 - 88,223,414 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	14	89,445,021 - 89,463,332 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	14	85,912,157 - 85,930,471 (+)	NCBI	Rnor_WKY
Rnor_6.0	14	89,314,234 - 89,334,060 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	89,314,176 - 89,334,276 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	89,651,264 - 89,669,630 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	89,669,068 - 89,688,775 (+)	NCBI
Celera	14	82,846,265 - 82,864,631 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic contact dermatitis (ISO)

long QT syndrome (ISO)

middle cerebral artery infarction (IEP)

pleomorphic xanthoastrocytoma (ISO)

respiratory allergy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (EXP)

4-hydroxyphenyl retinamide (ISO)

5-benzyl-1-(2-hydroxyethoxymethyl)uracil (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aconitine (EXP)

adenosine (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

bicalutamide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bleomycin A5 (ISO)

bortezomib (ISO)

butanal (ISO)

cadmium atom (ISO)

calciol (ISO)

calyculin a (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

chlordecone (ISO)

chloropicrin (ISO)

chloroprene (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

crotonaldehyde (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

cytidine (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

diquat (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

doxifluridine (ISO)

doxorubicin (ISO)

endosulfan (ISO)

ethanol (ISO)

formaldehyde (ISO)

guanosine (ISO)

hydrogen peroxide (ISO)

hydroquinone (ISO)

indometacin (ISO)

ivermectin (ISO)

Licochalcone B (ISO)

manganese(II) chloride (EXP)

menadione (ISO)

mercury dichloride (EXP)

methamphetamine (EXP)

methotrexate (ISO)

methylmercury chloride (EXP,ISO)

methylparaben (ISO)

Monobutylphthalate (ISO)

N-methyl-4-phenylpyridinium (EXP)

N-methyl-N-nitrosourea (EXP,ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nicotine (ISO)

obeticholic acid (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

pentobarbital (ISO)

perfluorononanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

progesterone (ISO)

pyrimidine (ISO)

rac-lactic acid (ISO)

resveratrol (EXP,ISO)

SB 431542 (ISO)

SCH 23390 (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

succimer (ISO)

sulforaphane (ISO)

sulindac sulfide (ISO)

tert-butyl hydroperoxide (ISO)

thalidomide (ISO)

thimerosal (ISO)

thioacetamide (EXP)

topotecan (EXP)

tributylstannane (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (EXP)

Triptolide (EXP)

tris(2-butoxyethyl) phosphate (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

urethane (ISO)

uridine (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to glucose starvation (IEP)

CMP catabolic process (ISO)

dCMP catabolic process (ISO)

dTMP catabolic process (ISO)

dUMP catabolic process (ISO)

pyrimidine nucleotide metabolic process (ISO)

UMP catabolic process (ISO)

UMP salvage (IEA,ISO)

uridine catabolic process (IBA,ISO)

uridine metabolic process (ISO)

Cellular Component

cytosol (IBA,ISO)

nucleoplasm (ISO)

Molecular Function

deoxyuridine phosphorylase activity (ISO)

identical protein binding (ISO)

thymidine phosphorylase activity (ISO)

uridine phosphorylase activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pyrimidine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase.	Choi JW, etal., J Neurotrauma. 2008 Jun;25(6):695-707.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7488099	PMID:7744869	PMID:12477932	PMID:15772079	PMID:19291308	PMID:20856879	PMID:23355744

Genomics

Comparative Map Data

Upp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	83,809,495 - 83,829,299 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	83,809,960 - 83,829,462 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	88,205,103 - 88,223,414 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	14	89,445,021 - 89,463,332 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	14	85,912,157 - 85,930,471 (+)	NCBI	Rnor_WKY
Rnor_6.0	14	89,314,234 - 89,334,060 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	89,314,176 - 89,334,276 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	89,651,264 - 89,669,630 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	89,669,068 - 89,688,775 (+)	NCBI
Celera	14	82,846,265 - 82,864,631 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

UPP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	48,088,704 - 48,108,736 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	7	48,088,628 - 48,108,736 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	48,128,301 - 48,148,333 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	48,094,880 - 48,114,855 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	48,227,538 - 48,247,515 (+)	NCBI		Celera
Cytogenetic Map	7	p12.3	NCBI
HuRef	7	48,013,948 - 48,033,924 (+)	NCBI		HuRef
CHM1_1	7	48,132,055 - 48,152,030 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	48,250,938 - 48,270,970 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	48,168,224 - 48,188,201 (+)	NCBI

Upp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	9,068,008 - 9,086,170 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	9,068,103 - 9,086,170 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	9,118,008 - 9,136,170 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	9,118,103 - 9,136,170 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	9,018,011 - 9,036,173 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	9,018,106 - 9,036,167 (+)	NCBI		MGSCv36	mm8
Celera	11	9,551,715 - 9,569,878 (+)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI

Upp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	5,365,877 - 5,385,336 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	5,365,912 - 5,385,336 (-)	NCBI	ChiLan1.0	ChiLan1.0

UPP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	48,838,901 - 48,858,189 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	48,838,893 - 48,858,185 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	48,729,975 - 48,749,598 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

UPP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	108,215 - 120,213 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	67,812 - 89,151 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	133,593 - 154,855 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	133,673 - 164,752 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	108,433 - 129,715 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	111,361 - 132,570 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	246,479 - 267,730 (+)	NCBI		UU_Cfam_GSD_1.0

Upp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	103,296,840 - 103,319,396 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	22,508,559 - 22,531,898 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936478	22,508,602 - 22,531,604 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UPP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	48,418,385 - 48,440,736 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	48,418,385 - 48,440,414 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

UPP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	10,686,600 - 10,707,181 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	10,686,093 - 10,706,347 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666062	11,525,130 - 11,545,495 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Upp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	5,517,387 - 5,531,594 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Upp1
231 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	82
Count of miRNA genes:	71
Interacting mature miRNAs:	73
Transcripts:	ENSRNOT00000006765
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	40793460	98037301	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42262529	95023211	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	50023211	95023211	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	55147478	100147478	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	55624247	100624247	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	55624247	100624247	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	56631369	101631369	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	58184885	103184885	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	70053989	104886043	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	70053989	104886043	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	73415323	92554092	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	73415323	92554092	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	95876975	Rat
631213	Bw60	Body weight QTL60	4.51		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	79950921	95876975	Rat
4889951	Bss92	Bone structure and strength QTL 92	3.9		tibia area (VT:1000281)	tibia-fibula cortical bone total cross-sectional area (CMO:0001721)	14	82057471	95876975	Rat

Markers in Region

RH131849

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	83,829,092 - 83,829,280 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	89,333,857 - 89,334,044	NCBI	Rnor6.0
Rnor_5.0	14	89,131,899 - 89,132,086	UniSTS	Rnor5.0
RGSC_v3.4	14	89,669,431 - 89,669,618	UniSTS	RGSC3.4
Celera	14	82,864,432 - 82,864,619	UniSTS
RH 3.4 Map	14	617.2	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	18									8	11
Low	1	25	57	41	19	41	8	11	68	35	32		8
Below cutoff									6		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001030025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC099752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006765 ⟹ ENSRNOP00000006765

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	83,809,960 - 83,829,462 (+)	Ensembl
Rnor_6.0 Ensembl	14	89,314,176 - 89,334,276 (+)	Ensembl

RefSeq Acc Id:

NM_001030025 ⟹ NP_001025196

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,810,924 - 83,829,292 (+)	NCBI
Rnor_6.0	14	89,315,690 - 89,334,056 (+)	NCBI
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI
RGSC_v3.4	14	89,651,264 - 89,669,630 (+)	RGD
Celera	14	82,846,265 - 82,864,631 (+)	RGD

Sequence:

show sequence

TGAGCGTCTTGGTGAAGTGACTCACTGGTGGGCCCTGACACTCTGGAAGTCTTCCCGAGAAGTG
GACATCAGTCTCTGACAGTCCCGCTACAGTGAGAAAATGGCAGCTACAGGAACTGAAGCAAAGG
ACCTGGAAAACCATCACAACAGTGACTGCCTCGTCCAGCTTTCAAATCCAAACATAGCCACGAT
GAAGGAAGACGTTCTCTACCATTTCAACCTCAGCACTAGCACACACGATTTCCCCGCTATGTTT
GGAGATGTGAAGTTTGTGTGTGTTGGTGGAAGCTCCTCCCGGATGAGCGCCTTCATCAAGTATG
TGGCCGCAGAGCTGGGCCTTGACCACCCAGGGAAAGAATATCCCAACATCTGCGCAGGCACTGA
CCGCTACGCCATGTATAAAGCCGGGCCCGTGCTGTCTGTGAGCCATGGCATGGGCATCCCTTCC
ATTGGGATCATGTTGCATGAGCTCATCAAGATGCTGTACCATGCCAGGTGCTCCAACATCACCA
TCATCCGCATTGGCACTTCAGGAGGGATAGGTCTGGAGCCTGGCTCTGTCGTCATCACGCAGCA
GGCAGTGGATGAGTGCTTCAAACCAGAGTTTGAGCAGATTGTGCTGGGAAAGCGGGTGACTCGA
AACACCAGCCTGGACGCGCAGCTGGTACAGGAGTTGATGCAGTGCTCCTCAGACCTGAACGAGT
TCCCCACTGTTGTGGGTAACACCATGTGCACCTTGGACTTCTATGAGGGGCAAGGCCGCCTGGA
TGGCGCCCTCTGCTCCTACACAGAGAAGGACAAACAGGCCTATCTGCGTGCAGCCCATGCCGCG
GGTGTCCGAAATATCGAGATGGAATCTTCAGTGTTTGCCACCATGTGCAGTGCCTGTGGCCTGA
AAGCGGCTGTGGTGTGTGTCACTCTTCTGGACCGTCTGCAAGGGGATCAGATCAACACTCCCCA
TAATGTGCTTGTGGAATACCAGCAAAGGCCGCAGCGGCTGGTGGGCCATTTCATCAAGAAGCGC
CTAGGGAGGGCCTGAGACCCGTGCCTTTCTGCTCGGGAGACGTTTCTGCAACTCCTGGGCAATA
AATCTATTTTTTCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_006251483 ⟹ XP_006251545

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,830 - 83,829,299 (+)	NCBI
Rnor_6.0	14	89,314,520 - 89,334,060 (+)	NCBI
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI

Sequence:

show sequence

TTAGCAGCTTGGTTATGATTTCGTCCATAGTAAGAGAGGCTATGGAGCTACGGAGATGGCTCTG
GATAACTTAAAATTGTCAGCTATCTCCAAAGAAAACTAGAAGGTGGAGGCTCCCGGGCAACTTT
TCCGGGTTCGGGTAGAGAAGGTGTGGACAGGGCGTGTCGGGGCGCCAGGCCCTAGCTGCTATCA
GCTGAGCCCTTCGGCCGAGCCAGAGCCCCGCGGTGACCCGTGGGCGGGGCTTCGGGTGACAGAT
CGGGGAAGGCGAAAGTGTGGTCAGAAAGGTTCTCCTTTCTGGTCCGCTCCCTCCTTTAAAAGGT
CTGGCGCGCAGCTTCTCTCTCACAGTTCTCCTGCGCGGCCGGCCGGGACTGAGCGTCTTGGTGA
AGTGACTCACTGGTGGGCCCTGACACTCTGGAAGTCTTCCCGAGAAGTGGACATCAGTCTCTGA
CAGTCCCGCTACAGTGAGAAAATGGCAGCTACAGGAACTGAAGCAAAGGACCTGGAAAACCATC
ACAACAGTGACTGCCTCGTCCAGCTTTCAAATCCAAACATAGCCACGATGAAGGAAGACGTTCT
CTACCATTTCAACCTCAGCACTAGCACACACGATTTCCCCGCTATGTTTGGAGATGTGAAGTTT
GTGTGTGTTGGTGGAAGCTCCTCCCGGATGAGCGCCTTCATCAAGTATGTGGCCGCAGAGCTGG
GCCTTGACCACCCAGGGAAAGAATATCCCAACATCTGCGCAGGCACTGACCGCTACGCCATGTA
TAAAGCCGGGCCCGTGCTGTCTGTGAGCCATGGCATGGGCATCCCTTCCATTGGGATCATGTTG
CATGAGCTCATCAAGATGCTGTACCATGCCAGGTGCTCCAACATCACCATCATCCGCATTGGCA
CTTCAGGAGGGATAGGTCTGGAGCCTGGCTCTGTCGTCATCACTCAGCAGGCAGTGGATGAGTG
CTTCAAACCAGAGTTTGAGCAGATTGTGCTGGGAAAGCGGGTGACTCGAAACACCAGCCTGGAC
GCGCAGCTGGTACAGGAGTTGATGCAGTGCTCCTCAGACCTGAACGAGTTCCCCACTGTTGTGG
GTAACACCATGTGCACCTTGGACTTCTATGAGGGGCAAGGCCGCCTGGATGGTGCCCTCTGCTC
CTACACAGAGAAGGACAAACAGGCCTATCTGCGTGCAGCCCATGCCGCAGGTGTCCGAAATATC
GAGATGGAATCTTCAGTGTTTGCCACCATGTGCAGTGCCTGTGGCCTGAAAGCGGCTGTGGTGT
GTGTCACTCTTCTGGACCGTCTGCAAGGGGATCAGATCAACACTCCCCATAATGTGCTTGTGGA
ATACCAGCAAAGGCCGCAGCGGCTGGTGGGCCATTTCATCAAGAAGCGCCTAGGGAGGGCCTGA
GACCCGTGCCTTTCTGCTCGGGAGACGTTTCTGCAACTCCTGGGCAATAAATCTATTTTTTCAT
AATGCA

hide sequence

RefSeq Acc Id:

XM_006251484 ⟹ XP_006251546

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,584 - 83,829,299 (+)	NCBI
Rnor_6.0	14	89,314,234 - 89,334,060 (+)	NCBI
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI

Sequence:

show sequence

TCCCCTAGCCTTCCCACAACCACAGAGGATATCCCTGGACCAGGAAGGACCCGGAGGGGGAGAA
AATAAAAATCAAAACAAAACAGAAACAGGCCCGAGATACTGAAAGGACACAGTTTACAACAGCC
TTGCTCTGCACTCTTGACCGCTTCCACACGGCCATTCATCTGTGGTACCTCCTTTCATCATTTC
CAGACAAATGGACCAGGGCCCTGGCGCTAGAGGTGACCTTGGGTAGCCATACAGCCGCTTCCAG
ATCTTTTCTTCGTCTGTGGAACAATCTTGGTGAAGTGACTCACTGGTGGGCCCTGACACTCTGG
AAGTCTTCCCGAGAAGTGGACATCAGTCTCTGACAGTCCCGCTACAGTGAGAAAATGGCAGCTA
CAGGAACTGAAGCAAAGGACCTGGAAAACCATCACAACAGTGACTGCCTCGTCCAGCTTTCAAA
TCCAAACATAGCCACGATGAAGGAAGACGTTCTCTACCATTTCAACCTCAGCACTAGCACACAC
GATTTCCCCGCTATGTTTGGAGATGTGAAGTTTGTGTGTGTTGGTGGAAGCTCCTCCCGGATGA
GCGCCTTCATCAAGTATGTGGCCGCAGAGCTGGGCCTTGACCACCCAGGGAAAGAATATCCCAA
CATCTGCGCAGGCACTGACCGCTACGCCATGTATAAAGCCGGGCCCGTGCTGTCTGTGAGCCAT
GGCATGGGCATCCCTTCCATTGGGATCATGTTGCATGAGCTCATCAAGATGCTGTACCATGCCA
GGTGCTCCAACATCACCATCATCCGCATTGGCACTTCAGGAGGGATAGGTCTGGAGCCTGGCTC
TGTCGTCATCACTCAGCAGGCAGTGGATGAGTGCTTCAAACCAGAGTTTGAGCAGATTGTGCTG
GGAAAGCGGGTGACTCGAAACACCAGCCTGGACGCGCAGCTGGTACAGGAGTTGATGCAGTGCT
CCTCAGACCTGAACGAGTTCCCCACTGTTGTGGGTAACACCATGTGCACCTTGGACTTCTATGA
GGGGCAAGGCCGCCTGGATGGTGCCCTCTGCTCCTACACAGAGAAGGACAAACAGGCCTATCTG
CGTGCAGCCCATGCCGCAGGTGTCCGAAATATCGAGATGGAATCTTCAGTGTTTGCCACCATGT
GCAGTGCCTGTGGCCTGAAAGCGGCTGTGGTGTGTGTCACTCTTCTGGACCGTCTGCAAGGGGA
TCAGATCAACACTCCCCATAATGTGCTTGTGGAATACCAGCAAAGGCCGCAGCGGCTGGTGGGC
CATTTCATCAAGAAGCGCCTAGGGAGGGCCTGAGACCCGTGCCTTTCTGCTCGGGAGACGTTTC
TGCAACTCCTGGGCAATAAATCTATTTTTTCATAATGCA

hide sequence

RefSeq Acc Id:

XM_006251485 ⟹ XP_006251547

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,552 - 83,829,299 (+)	NCBI
Rnor_6.0	14	89,314,234 - 89,334,060 (+)	NCBI
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI

Sequence:

show sequence

TCCCCTAGCCTTCCCACAACCACAGAGGATATCCCTGGACCAGGAAGGACCCGGAGGGGGAGAA
AATAAAAATCAAAACAAAACAGAAACAGGCCCGAGATACTGAAAGGACACAGTTTACAACAGCC
TTGCTCTGCACTCTTGACCGCTTCCACACGGCCATTCATCTGTGGTACCTCCTTTCATCATTTC
CAGACAAATGGACCAGGGCCCTGGCGCTAGAGTCTTGGTGAAGTGACTCACTGGTGGGCCCTGA
CACTCTGGAAGTCTTCCCGAGAAGTGGACATCAGTCTCTGACAGTCCCGCTACAGTGAGAAAAT
GGCAGCTACAGGAACTGAAGCAAAGGACCTGGAAAACCATCACAACAGTGACTGCCTCGTCCAG
CTTTCAAATCCAAACATAGCCACGATGAAGGAAGACGTTCTCTACCATTTCAACCTCAGCACTA
GCACACACGATTTCCCCGCTATGTTTGGAGATGTGAAGTTTGTGTGTGTTGGTGGAAGCTCCTC
CCGGATGAGCGCCTTCATCAAGTATGTGGCCGCAGAGCTGGGCCTTGACCACCCAGGGAAAGAA
TATCCCAACATCTGCGCAGGCACTGACCGCTACGCCATGTATAAAGCCGGGCCCGTGCTGTCTG
TGAGCCATGGCATGGGCATCCCTTCCATTGGGATCATGTTGCATGAGCTCATCAAGATGCTGTA
CCATGCCAGGTGCTCCAACATCACCATCATCCGCATTGGCACTTCAGGAGGGATAGGTCTGGAG
CCTGGCTCTGTCGTCATCACTCAGCAGGCAGTGGATGAGTGCTTCAAACCAGAGTTTGAGCAGA
TTGTGCTGGGAAAGCGGGTGACTCGAAACACCAGCCTGGACGCGCAGCTGGTACAGGAGTTGAT
GCAGTGCTCCTCAGACCTGAACGAGTTCCCCACTGTTGTGGGTAACACCATGTGCACCTTGGAC
TTCTATGAGGGGCAAGGCCGCCTGGATGGTGCCCTCTGCTCCTACACAGAGAAGGACAAACAGG
CCTATCTGCGTGCAGCCCATGCCGCAGGTGTCCGAAATATCGAGATGGAATCTTCAGTGTTTGC
CACCATGTGCAGTGCCTGTGGCCTGAAAGCGGCTGTGGTGTGTGTCACTCTTCTGGACCGTCTG
CAAGGGGATCAGATCAACACTCCCCATAATGTGCTTGTGGAATACCAGCAAAGGCCGCAGCGGC
TGGTGGGCCATTTCATCAAGAAGCGCCTAGGGAGGGCCTGAGACCCGTGCCTTTCTGCTCGGGA
GACGTTTCTGCAACTCCTGGGCAATAAATCTATTTTTTCATAATGCA

hide sequence

RefSeq Acc Id:

XM_006251487 ⟹ XP_006251549

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,817 - 83,829,299 (+)	NCBI
Rnor_6.0	14	89,314,520 - 89,334,060 (+)	NCBI
Rnor_5.0	14	89,112,302 - 89,132,102 (+)	NCBI

Sequence:

show sequence

TTAGCAGCTTGGTTATGATTTCGTCCATAGTAAGAGAGGCTATGGAGCTACGGAGATGGCTCTG
GATAACTTAAAATTGTCAGCTATCTCCAAAGAAAACTAGAAGGTGGAGGCTCCCGGGCAACTTT
TCCGGGTTCGGGTAGAGAAGGTGTGGACAGGGCGTGTCGGGGCGCCAGGCCCTAGCTGCTATCA
GCTGAGCCCTTCGGCCGAGCCAGAGCCCCGCGGTGACCCGTGGGCGGGGCTTCGGGTGACAGAT
CGGGGAAGGCGAAAGTGTGGTCAGAAAGGTTCTCCTTTCTGGTCCGCTCCCTCCTTTAAAAGGT
CTGGCGCGCAGCTTCTCTCTCACAGTTCTCCTGCGCGGCCGGCCGGGACTGAGCGTCTTGGTGA
AGTGACTCACTGGTGGGCCCTGACACTCTGGAAGTCTTCCCGAGAAGTGGACATCAGTCTCTGA
CAGTCCCGCTACAGTGAGAAAATGGCAGCTACAGGAACTGAAGCAAAGGACCTGGAAAACCATC
ACAATGACTGCCTCGTCCAGCTTTCAAATCCAAACATAGCCACGATGAAGGAAGACGTTCTCTA
CCATTTCAACCTCAGCACTAGCACACACGATTTCCCCGCTATGTTTGGAGATGTGAAGTTTGTG
TGTGTTGGTGGAAGCTCCTCCCGGATGAGCGCCTTCATCAAGTATGTGGCCGCAGAGCTGGGCC
TTGACCACCCAGGGAAAGAATATCCCAACATCTGCGCAGGCACTGACCGCTACGCCATGTATAA
AGCCGGGCCCGTGCTGTCTGTGAGCCATGGCATGGGCATCCCTTCCATTGGGATCATGTTGCAT
GAGCTCATCAAGATGCTGTACCATGCCAGGTGCTCCAACATCACCATCATCCGCATTGGCACTT
CAGGAGGGATAGGTCTGGAGCCTGGCTCTGTCGTCATCACTCAGCAGGCAGTGGATGAGTGCTT
CAAACCAGAGTTTGAGCAGATTGTGCTGGGAAAGCGGGTGACTCGAAACACCAGCCTGGACGCG
CAGCTGGTACAGGAGTTGATGCAGTGCTCCTCAGACCTGAACGAGTTCCCCACTGTTGTGGGTA
ACACCATGTGCACCTTGGACTTCTATGAGGGGCAAGGCCGCCTGGATGGTGCCCTCTGCTCCTA
CACAGAGAAGGACAAACAGGCCTATCTGCGTGCAGCCCATGCCGCAGGTGTCCGAAATATCGAG
ATGGAATCTTCAGTGTTTGCCACCATGTGCAGTGCCTGTGGCCTGAAAGCGGCTGTGGTGTGTG
TCACTCTTCTGGACCGTCTGCAAGGGGATCAGATCAACACTCCCCATAATGTGCTTGTGGAATA
CCAGCAAAGGCCGCAGCGGCTGGTGGGCCATTTCATCAAGAAGCGCCTAGGGAGGGCCTGAGAC
CCGTGCCTTTCTGCTCGGGAGACGTTTCTGCAACTCCTGGGCAATAAATCTATTTTTTCATAAT
GCA

hide sequence

RefSeq Acc Id:

XM_039091760 ⟹ XP_038947688

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,495 - 83,829,299 (+)	NCBI

RefSeq Acc Id:

XM_039091762 ⟹ XP_038947690

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,595 - 83,829,299 (+)	NCBI

RefSeq Acc Id:

XM_039091763 ⟹ XP_038947691

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,820 - 83,829,299 (+)	NCBI

RefSeq Acc Id:

XM_039091764 ⟹ XP_038947692

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	83,809,550 - 83,829,299 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001025196	(Get FASTA)	NCBI Sequence Viewer
	XP_006251545	(Get FASTA)	NCBI Sequence Viewer
	XP_006251546	(Get FASTA)	NCBI Sequence Viewer
	XP_006251547	(Get FASTA)	NCBI Sequence Viewer
	XP_006251549	(Get FASTA)	NCBI Sequence Viewer
	XP_038947688	(Get FASTA)	NCBI Sequence Viewer
	XP_038947690	(Get FASTA)	NCBI Sequence Viewer
	XP_038947691	(Get FASTA)	NCBI Sequence Viewer
	XP_038947692	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99752	(Get FASTA)	NCBI Sequence Viewer
	EDL76038	(Get FASTA)	NCBI Sequence Viewer
	EDL76039	(Get FASTA)	NCBI Sequence Viewer
	EDL76040	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001025196 ⟸ NM_001030025

- UniProtKB:

Q499V1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAATGTEAKDLENHHNSDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSS
SRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKML
YHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQEL
MQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVF
ATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA

hide sequence

RefSeq Acc Id:	XP_006251546 ⟸ XM_006251484
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAATGTEAKDLENHHNSDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSS SRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKML YHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQEL MQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVF ATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA hide sequence

RefSeq Acc Id:	XP_006251547 ⟸ XM_006251485
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAATGTEAKDLENHHNSDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSS SRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKML YHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQEL MQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVF ATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA hide sequence

RefSeq Acc Id:	XP_006251549 ⟸ XM_006251487
- Peptide Label:	isoform X2
- UniProtKB:	F7F0D5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAATGTEAKDLENHHNDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSSS RMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKMLY HARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQELM QCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVFA TMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA hide sequence

RefSeq Acc Id:	XP_006251545 ⟸ XM_006251483
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAATGTEAKDLENHHNSDCLVQLSNPNIATMKEDVLYHFNLSTSTHDFPAMFGDVKFVCVGGSS SRMSAFIKYVAAELGLDHPGKEYPNICAGTDRYAMYKAGPVLSVSHGMGIPSIGIMLHELIKML YHARCSNITIIRIGTSGGIGLEPGSVVITQQAVDECFKPEFEQIVLGKRVTRNTSLDAQLVQEL MQCSSDLNEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLRAAHAAGVRNIEMESSVF ATMCSACGLKAAVVCVTLLDRLQGDQINTPHNVLVEYQQRPQRLVGHFIKKRLGRA hide sequence

RefSeq Acc Id:

ENSRNOP00000006765 ⟸ ENSRNOT00000006765

RefSeq Acc Id:	XP_038947688 ⟸ XM_039091760
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038947692 ⟸ XM_039091764
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038947690 ⟸ XM_039091762
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038947691 ⟸ XM_039091763
- Peptide Label:	isoform X1
- UniProtKB:	Q499V1 (UniProtKB/TrEMBL)

Protein Domains

Nucleoside phosphorylase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q499V1-F1-model_v2	AlphaFold	Q499V1	1-312	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699490

Promoter ID:

EPDNEW_R10013

Type:

single initiation site

Name:

Upp1_2

Description:

uridine phosphorylase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R10014

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	89,314,249 - 89,314,309	EPDNEW

RGD ID:

13699491

Promoter ID:

EPDNEW_R10014

Type:

multiple initiation site

Name:

Upp1_1

Description:

uridine phosphorylase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R10013

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	89,314,861 - 89,314,921	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305566	AgrOrtholog
BioCyc Gene	G2FUF-15021	BioCyc
BioCyc Pathway	PWY-7181 [pyrimidine deoxyribonucleosides degradation]	BioCyc
	PWY0-1295 [pyrimidine ribonucleosides degradation]	BioCyc
Ensembl Genes	ENSRNOG00000004972	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006765	ENTREZGENE
	ENSRNOP00000006765.5	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006765	ENTREZGENE
	ENSRNOT00000006765.8	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1580	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5623209	IMAGE-MGC_LOAD
InterPro	Nucleoside_phosphorylase	UniProtKB/TrEMBL
	Nucleoside_phosphorylase_CS	UniProtKB/TrEMBL
	Nucleoside_phosphorylase_sf	UniProtKB/TrEMBL
	Uridine_phosphorylase_euk	UniProtKB/TrEMBL
KEGG Report	rno:289801	UniProtKB/TrEMBL
MGC_CLONE	MGC:124655	IMAGE-MGC_LOAD
NCBI Gene	289801	ENTREZGENE
PANTHER	URIDINE PHOSPHORYLASE	UniProtKB/TrEMBL
	URIDINE PHOSPHORYLASE 1	UniProtKB/TrEMBL
Pfam	PNP_UDP_1	UniProtKB/TrEMBL
PharmGKB	UPP1	RGD
PhenoGen	Upp1	PhenoGen
PROSITE	PNP_UDP_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53167	UniProtKB/TrEMBL
TIGRFAMs	euk_UDPppase	UniProtKB/TrEMBL
UniProt	F7F0D5	ENTREZGENE, UniProtKB/TrEMBL
	Q499V1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Upp1	uridine phosphorylase 1	Upp1_predicted	uridine phosphorylase 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Upp1_predicted	uridine phosphorylase 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)