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Gene: Znrf3 (zinc and ring finger 3) Rattus norvegicus
Symbol: Znrf3
Name: zinc and ring finger 3
Description: Predicted to have frizzled binding activity and ubiquitin-protein transferase activity. Predicted to be involved in cellular protein metabolic process; regulation of Wnt signaling pathway; and stem cell proliferation. Predicted to localize to integral component of plasma membrane. Orthologous to human ZNRF3 (zinc and ring finger 3); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 1-naphthyl isothiocyanate; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase ZNRF3; LOC685487; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF3; rCG35969-like; similar to ring finger protein 43
Homo sapiens (human) : ZNRF3 (zinc and ring finger 3)  HGNC  Alliance
Mus musculus (house mouse) : Znrf3 (zinc and ring finger 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znrf3 (zinc and ring finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNRF3 (zinc and ring finger 3)
Canis lupus familiaris (dog) : ZNRF3 (zinc and ring finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znrf3 (zinc and ring finger 3)
Sus scrofa (pig) : ZNRF3 (zinc and ring finger 3)
Chlorocebus sabaeus (African green monkey) : ZNRF3 (zinc and ring finger 3)
Heterocephalus glaber (naked mole-rat) : Znrf3 (zinc and ring finger 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01485,527,099 - 85,586,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,200,958 - 86,256,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,927,245 - 85,982,249 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1479,049,064 - 79,109,279 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Znrf3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593771
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.