Gene: Xpo1 (exportin 1) Rattus norvegicus
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Symbol: Xpo1
Name: exportin 1
Description: Exhibits protein domain specific binding activity; involved in negative regulation of transcription by RNA polymerase II, protein export from nucleus, and response to drug; predicted to localize to several cellular components, including the annulate lamellae, cytosol, and intracellular organelle; orthologous to human XPO1 (exportin 1); PARTICIPATES IN CRM1 export pathway; Hedgehog signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: chromosome region maintenance 1 protein homolog; exp1; exportin 1 (CRM1, yeast, homolog); exportin 1, CRM1 homolog; exportin 1, CRM1 homolog (yeast); exportin-1
Orthologs:
Homo sapiens (human) : XPO1 (exportin 1)  HGNC  Alliance
Mus musculus (house mouse) : Xpo1 (exportin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpo1 (exportin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XPO1 (exportin 1)
Canis lupus familiaris (dog) : XPO1 (exportin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpo1 (exportin 1)
Sus scrofa (pig) : XPO1 (exportin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.014108,007,421 - 108,049,088 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014108,082,784 - 108,124,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414103,943,249 - 103,978,717 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114103,962,459 - 103,997,928 (+)NCBI
Celera1496,216,463 - 96,251,770 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Xpo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620517
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.