Gene: Slc5a1 (solute carrier family 5 member 1) Rattus norvegicus
Analyze
Symbol:
Slc5a1
Name:
solute carrier family 5 member 1
Description:
Exhibits glucose:sodium symporter activity. Predicted to be involved in several processes, including glucose transmembrane transport; intestinal absorption; and metanephros development. Localizes to the apical plasma membrane; brush border membrane; and cell-cell junction. Orthologous to human SLC5A1 (solute carrier family 5 member 1); PARTICIPATES IN lactose degradation pathway; sodium-glucose cotransporter mediated glucose transport pathway; trehalose degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; aldehydo-D-glucose; ammonium chloride.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
high affinity sodium-glucose cotransporter; MGC93553; Na(+)/glucose cotransporter 1; SGLT1; SGLT1a; sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1; Solute carrier family 5 member alpha 1 (Na+/glucose cotransporter); solute carrier family 5, member 1; Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SLC5A1 (solute carrier family 5 member 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Slc5a1 (solute carrier family 5 (sodium/glucose cotransporter), member 1) HGNC
Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Slc5a1 (solute carrier family 5 member 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SLC5A1 (solute carrier family 5 member 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SLC5A1 (solute carrier family 5 member 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SLC5A1 (solute carrier family 5 member 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
SLC5A4 (solute carrier family 5 member 4) HGNC
OrthoDB
Alliance orthologs 3
Mus musculus (house mouse):
Slc5a1 (solute carrier family 5 (sodium/glucose cotransporter), member 1)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
SLC5A1 (solute carrier family 5 member 1)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
slc5a1 (solute carrier family 5 member 1)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information:
Annotation category: suggests misassembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 14 82,910,448 - 82,975,303 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 14 82,909,981 - 82,975,263 (-) Ensembl Rnor_5.0 14 83,595,212 - 83,660,531 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 14 83,311,232 - 83,370,657 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 14 83,313,626 - 83,376,968 (-) NCBI Celera 14 76,469,843 - 76,534,501 (-) NCBI Celera Cytogenetic Map 14 q21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
genetic disease ISO RGD:732146 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:18288487 more ... Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:9309206 Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:12139397 more ... Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:2008213 more ... Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:25741868 Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:20486940 more ... Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by term: Congenital glucose-galactose malabsorption ClinVar PMID:24033266 Glucose-Galactose Malabsorption ISO RGD:732146 8554872 ClinVar Annotator: match by OMIM:606824 ClinVar PMID:20486940
Imported Annotations - OMIM
Glucose-Galactose Malabsorption ISO RGD:732146 7240710 OMIM
(-)-citrinin multiple interactions ISO RGD:732146 6480464 [Citrinin co-treated with ochratoxin A] results in decreased expression of SLC5A1 mRNA CTD PMID:29673704 (S)-naringenin multiple interactions ISO RGD:732146 6480464 naringenin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 1,1-dichloroethene increases expression ISO RGD:11313 6480464 vinylidene chloride results in increased expression of SLC5A1 mRNA CTD PMID:26682919 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:11313 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:11313 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:11313 6480464 Tetrachlorodibenzodioxin results in increased expression of SGLT1 mRNA, Tetrachlorodibenzodioxin results in increased expression of SGLT1 protein CTD PMID:15885268 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:11313 6480464 Tetrachlorodibenzodioxin affects the expression of SLC5A1 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732146 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC5A1 mRNA CTD PMID:23152189 2-hydroxypropanoic acid decreases expression ISO RGD:732146 6480464 Lactic Acid results in decreased expression of SLC5A1 mRNA CTD PMID:30851411 5-fluorouracil increases expression ISO RGD:11313 6480464 Fluorouracil results in increased expression of SLC5A1 protein CTD PMID:15986457 aldehydo-D-glucose affects uptake ISO RGD:732146 6480464 SLC5A1 protein affects the uptake of Glucose CTD PMID:23927891 aldehydo-D-glucose increases expression ISO RGD:11313 6480464 Glucose results in increased expression of SLC5A1 mRNA CTD PMID:12937289 aldehydo-D-glucose multiple interactions ISO RGD:11313 6480464 [gentamicin C results in decreased expression of SLC5A1 protein] which results in decreased uptake of Glucose, [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose CTD PMID:12927799 aldehydo-D-glucose affects transport ISO RGD:732146 6480464 SLC5A1 protein affects the transport of Glucose CTD PMID:17288452 aldehydo-D-glucose multiple interactions ISO RGD:732146 6480464 Glucose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] CTD PMID:16300400 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SLC5A1 protein CTD PMID:8048533 aldehydo-D-glucose multiple interactions EXP 6480464 [Cisplatin results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose, [Gentamicins results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose CTD PMID:18656965 alpha-D-galactose affects transport ISO RGD:732146 6480464 SLC5A1 protein affects the transport of Galactose CTD PMID:17288452 alpha-D-galactose multiple interactions ISO RGD:732146 6480464 Galactose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] CTD PMID:16300400 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLC5A1 mRNA CTD PMID:16483693 apigenin multiple interactions ISO RGD:732146 6480464 Apigenin analog inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 arsane multiple interactions EXP 6480464 [Arsenic co-treated with Lead] results in increased activity of SLC5A1 protein CTD PMID:22354675 arsenic atom multiple interactions EXP 6480464 [Arsenic co-treated with Lead] results in increased activity of SLC5A1 protein CTD PMID:22354675 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SLC5A1 mRNA CTD PMID:25181051 , PMID:27178563 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLC5A1 mRNA CTD PMID:30903817 cadmium atom multiple interactions EXP 6480464 [Cadmium binds to SLC5A1 protein] which affects the folding of SLC5A1 protein, Cadmium inhibits the reaction [SLC5A1 results in increased uptake of methylglucoside] CTD PMID:15829715 cadmium atom decreases expression ISO RGD:11313 6480464 Cadmium results in decreased expression of SLC5A1 mRNA CTD PMID:11749115 more ... cadmium atom multiple interactions ISO RGD:11313 6480464 Cadmium inhibits the reaction [SP1 protein binds to SLC5A1 promoter] CTD PMID:15664265 cadmium atom multiple interactions ISO RGD:732146 6480464 Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter], Zinc inhibits the reaction [Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter]] CTD PMID:20073493 cadmium atom affects binding EXP 6480464 Cadmium binds to SLC5A1 protein CTD PMID:15829715 cadmium dichloride multiple interactions ISO RGD:11313 6480464 Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter] more ... CTD PMID:20060848 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SLC5A1 protein CTD PMID:25588984 cadmium dichloride decreases expression ISO RGD:11313 6480464 Cadmium Chloride results in decreased expression of SLC5A1 mRNA CTD PMID:20060848 , PMID:9512726 calcium atom multiple interactions EXP 6480464 SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] CTD PMID:17272349 calcium(0) multiple interactions EXP 6480464 SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] CTD PMID:17272349 carbon nanotube increases expression ISO RGD:11313 6480464 Nanotubes, Carbon analog results in increased expression of SLC5A1 mRNA, Nanotubes, Carbon results in increased expression of SLC5A1 mRNA CTD PMID:25554681 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of SLC5A1 mRNA CTD PMID:23125180 choline multiple interactions ISO RGD:11313 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC5A1 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO RGD:11313 6480464 chromium hexavalent ion affects the expression of SLC5A1 mRNA CTD PMID:28472532 cisplatin decreases expression EXP 6480464 [Cisplatin results in decreased expression of HNF1A mRNA] which results in decreased expression of SLC5A1 mRNA, Cisplatin results in decreased expression of SLC5A1 mRNA CTD PMID:18656965 cisplatin multiple interactions EXP 6480464 [Cisplatin results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose CTD PMID:18656965 copper atom decreases expression ISO RGD:11313 6480464 Copper results in decreased expression of SLC5A1 mRNA CTD PMID:9512726 copper(0) decreases expression ISO RGD:11313 6480464 Copper results in decreased expression of SLC5A1 mRNA CTD PMID:9512726 crocidolite asbestos increases expression ISO RGD:732146 6480464 Asbestos, Crocidolite results in increased expression of SLC5A1 mRNA CTD PMID:25351596 D-glucose affects uptake ISO RGD:732146 6480464 SLC5A1 protein affects the uptake of Glucose CTD PMID:23927891 D-glucose multiple interactions EXP 6480464 [Cisplatin results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose, [Gentamicins results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose CTD PMID:18656965 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SLC5A1 protein CTD PMID:8048533 D-glucose multiple interactions ISO RGD:732146 6480464 Glucose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] CTD PMID:16300400 D-glucose multiple interactions ISO RGD:11313 6480464 [gentamicin C results in decreased expression of SLC5A1 protein] which results in decreased uptake of Glucose, [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose CTD PMID:12927799 D-glucose increases expression ISO RGD:11313 6480464 Glucose results in increased expression of SLC5A1 mRNA CTD PMID:12937289 D-glucose affects transport ISO RGD:732146 6480464 SLC5A1 protein affects the transport of Glucose CTD PMID:17288452 dextran sulfate multiple interactions ISO RGD:11313 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A1 mRNA CTD PMID:29950665 dibenzo[a,l]pyrene decreases expression ISO RGD:11313 6480464 dibenzo(a, l)pyrene results in decreased expression of SLC5A1 mRNA CTD PMID:25908611 doxorubicin decreases expression ISO RGD:732146 6480464 Doxorubicin results in decreased expression of SLC5A1 mRNA CTD PMID:29803840 , PMID:30031762 ethanol decreases expression ISO RGD:732146 6480464 Ethanol results in decreased expression of SLC5A1 mRNA CTD PMID:31059573 folic acid multiple interactions ISO RGD:11313 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC5A1 mRNA CTD PMID:20938992 fructose multiple interactions ISO RGD:11313 6480464 lactisole inhibits the reaction [Fructose results in increased expression of SLC5A1 mRNA] CTD PMID:17786952 fructose increases expression ISO RGD:11313 6480464 Fructose results in increased expression of SLC5A1 mRNA CTD PMID:12937289 , PMID:17786952 fructose increases expression EXP 6480464 Fructose results in increased expression of SLC5A1 mRNA, Fructose results in increased expression of SLC5A1 protein CTD PMID:10222385 more ... galactose multiple interactions ISO RGD:732146 6480464 Galactose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] CTD PMID:16300400 galactose affects transport ISO RGD:732146 6480464 SLC5A1 protein affects the transport of Galactose CTD PMID:17288452 gentamycin decreases expression EXP 6480464 [Gentamicins results in decreased expression of HNF1A mRNA] which results in decreased expression of SLC5A1 mRNA, Gentamicins results in decreased expression of SLC5A1 mRNA CTD PMID:18656965 gentamycin multiple interactions EXP 6480464 [Gentamicins results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose CTD PMID:18656965 gentamycin C decreases expression ISO RGD:11313 6480464 gentamicin C results in decreased expression of SLC5A1 mRNA, gentamicin C results in decreased expression of SLC5A1 protein CTD PMID:12927799 gentamycin C multiple interactions ISO RGD:11313 6480464 [gentamicin C results in decreased expression of SLC5A1 protein] which results in decreased uptake of Glucose CTD PMID:12927799 glucose affects uptake ISO RGD:732146 6480464 SLC5A1 protein affects the uptake of Glucose CTD PMID:23927891 glucose multiple interactions EXP 6480464 [Cisplatin results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose, [Gentamicins results in decreased expression of SLC5A1 mRNA] which affects the transport of Glucose CTD PMID:18656965 glucose increases expression EXP 6480464 Glucose results in increased expression of SLC5A1 protein CTD PMID:8048533 glucose multiple interactions ISO RGD:732146 6480464 Glucose inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside] CTD PMID:16300400 glucose multiple interactions ISO RGD:11313 6480464 [gentamicin C results in decreased expression of SLC5A1 protein] which results in decreased uptake of Glucose, [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose CTD PMID:12927799 glucose increases expression ISO RGD:11313 6480464 Glucose results in increased expression of SLC5A1 mRNA CTD PMID:12937289 glucose affects transport ISO RGD:732146 6480464 SLC5A1 protein affects the transport of Glucose CTD PMID:17288452 glycerol increases expression EXP 6480464 Glycerol results in increased expression of SLC5A1 mRNA CTD PMID:10222385 GW 4064 increases expression ISO RGD:11313 6480464 GW 4064 results in increased expression of SLC5A1 mRNA CTD PMID:26655953 hydroquinone increases expression ISO RGD:732146 6480464 hydroquinone results in increased expression of SLC5A1 mRNA CTD PMID:31256213 L-methionine multiple interactions ISO RGD:11313 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLC5A1 mRNA CTD PMID:20938992 lead(0) multiple interactions EXP 6480464 [Arsenic co-treated with Lead] results in increased activity of SLC5A1 protein CTD PMID:22354675 lead(2+) multiple interactions EXP 6480464 [Arsenic co-treated with Lead] results in increased activity of SLC5A1 protein CTD PMID:22354675 luteolin multiple interactions ISO RGD:732146 6480464 Luteolin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 ochratoxin A decreases expression ISO RGD:732146 6480464 ochratoxin A results in decreased expression of SLC5A1 mRNA CTD PMID:29673704 ochratoxin A multiple interactions ISO RGD:732146 6480464 [Citrinin co-treated with ochratoxin A] results in decreased expression of SLC5A1 mRNA CTD PMID:29673704 ozone multiple interactions ISO RGD:11313 6480464 [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of SLC5A1 mRNA CTD PMID:25658374 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SLC5A1 protein CTD PMID:27324791 phlorizin multiple interactions ISO RGD:732146 6480464 Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside], Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:16300400 more ... phlorizin multiple interactions EXP 6480464 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside CTD PMID:12663055 phlorizin decreases activity EXP 6480464 Phlorhizin results in decreased activity of SLC5A1 protein CTD PMID:12663055 phlorizin multiple interactions ISO RGD:11313 6480464 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose CTD PMID:12927799 phlorizin decreases activity ISO RGD:11313 6480464 Phlorhizin results in decreased activity of SLC5A1 protein CTD PMID:12927799 phlorizin affects binding ISO RGD:732146 6480464 SLC5A1 protein binds to Phlorhizin CTD PMID:17983207 quercetin multiple interactions ISO RGD:732146 6480464 Quercetin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO RGD:732146 6480464 isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO RGD:732146 6480464 isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 quercetin 4'-O-beta-D-glucopyranoside multiple interactions EXP 6480464 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside CTD PMID:12663055 quercetin 4'-O-beta-D-glucopyranoside multiple interactions ISO RGD:732146 6480464 spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 rac-lactic acid decreases expression ISO RGD:732146 6480464 Lactic Acid results in decreased expression of SLC5A1 mRNA CTD PMID:30851411 resveratrol affects uptake ISO RGD:732146 6480464 SLC5A1 protein affects the uptake of resveratrol CTD PMID:23927891 silicon dioxide increases expression ISO RGD:732146 6480464 Silicon Dioxide results in increased expression of SLC5A1 mRNA CTD PMID:25351596 sirolimus decreases expression EXP 6480464 Sirolimus results in decreased expression of SLC5A1 mRNA CTD PMID:21865292 sodium arsenite affects methylation ISO RGD:732146 6480464 sodium arsenite affects the methylation of SLC5A1 gene CTD PMID:28589171 sodium atom multiple interactions ISO RGD:732146 6480464 [Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside more ... CTD PMID:16300400 sucrose increases expression EXP 6480464 Sucrose results in increased expression of SLC5A1 mRNA, Sucrose results in increased expression of SLC5A1 protein CTD PMID:10222385 , PMID:8048533 tamoxifen decreases expression ISO RGD:11313 6480464 Tamoxifen results in decreased expression of SLC5A1 mRNA CTD PMID:25123088 Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of SLC5A1 mRNA CTD PMID:21515302 titanium dioxide multiple interactions ISO RGD:11313 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A1 mRNA CTD PMID:29950665 trans-piceid affects uptake ISO RGD:732146 6480464 SLC5A1 protein affects the uptake of polydatin CTD PMID:15686436 triclosan decreases expression ISO RGD:732146 6480464 Triclosan results in decreased expression of SLC5A1 mRNA CTD PMID:30510588 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SLC5A1 mRNA, troglitazone results in decreased expression of SLC5A1 protein CTD PMID:11244250 venlafaxine hydrochloride increases expression EXP 6480464 Venlafaxine Hydrochloride results in increased expression of SLC5A1 mRNA CTD PMID:25423262 zinc atom multiple interactions ISO RGD:732146 6480464 Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter], Zinc inhibits the reaction [Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter]] CTD PMID:20073493 zinc atom decreases expression ISO RGD:11313 6480464 Zinc results in decreased expression of SLC5A1 mRNA CTD PMID:9512726 zinc dichloride multiple interactions ISO RGD:11313 6480464 zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]], zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A1 mRNA] CTD PMID:20060848 zinc(0) multiple interactions ISO RGD:732146 6480464 Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter], Zinc inhibits the reaction [Cadmium inhibits the reaction [[SP1 protein binds to Zinc] which binds to SLC5A1 promoter]] CTD PMID:20073493 zinc(0) decreases expression ISO RGD:11313 6480464 Zinc results in decreased expression of SLC5A1 mRNA CTD PMID:9512726
Gene-Chemical Interaction Annotations
