Acox3 (acyl-CoA oxidase 3, pristanoyl)

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Gene: Acox3 (acyl-CoA oxidase 3, pristanoyl) Rattus norvegicus

Analyze

Symbol:

Acox3

Name:

acyl-CoA oxidase 3, pristanoyl

RGD ID:

69245

Description:

Enables fatty acid binding activity; flavin adenine dinucleotide binding activity; and pristanoyl-CoA oxidase activity. Involved in fatty acid beta-oxidation using acyl-CoA oxidase. Located in peroxisome. Orthologous to human ACOX3 (acyl-CoA oxidase 3, pristanoyl); PARTICIPATES IN alpha-linolenic acid metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

acyl-Coenzyme A oxidase 3; acyl-Coenzyme A oxidase 3, pristanoyl; branched-chain acyl-CoA oxidase; BRCACox; peroxisomal acyl-coenzyme A oxidase 3; pristanoyl-CoA oxidase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Acox3 (acyl-Coenzyme A oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acox3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acox3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acox3 (acyl-CoA oxidase 3, pristanoyl)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ACOX3 (acyl-CoA oxidase 3, pristanoyl)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acox3 (acyl-Coenzyme A oxidase 3, pristanoyl)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acox3 (acyl-CoA oxidase 3, pristanoyl)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17544	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG9527	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	acox-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acox3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	75,133,986 - 75,176,767 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	75,094,676 - 75,176,205 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	79,575,514 - 79,629,707 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	80,816,379 - 80,870,575 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	77,261,371 - 77,315,558 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	80,313,202 - 80,358,115 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	80,314,431 - 80,355,420 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	79,942,668 - 79,982,780 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	80,769,000 - 80,809,809 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	80,771,390 - 80,812,200 (-)	NCBI
Celera	14	74,065,866 - 74,104,532 (-)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-diaminodiphenylmethane (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

entacapone (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

indometacin (EXP)

methamphetamine (EXP)

methapyrilene (ISO)

methylmercury chloride (ISO)

microcystin-LR (ISO)

N-methyl-4-phenylpyridinium (EXP)

nefazodone (EXP)

nimesulide (EXP)

obeticholic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

Propiverine (EXP)

quercetin (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

tolcapone (EXP)

triphenyl phosphate (EXP)

triptonide (ISO)

valdecoxib (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid beta-oxidation (IEA)

fatty acid beta-oxidation using acyl-CoA oxidase (IBA,IDA,IEA)

lipid homeostasis (IBA)

Cellular Component

peroxisome (IBA,IDA,IEA,ISO)

Molecular Function

acyl-CoA oxidase activity (IEA)

FAD binding (IEA)

fatty acid binding (IBA,IDA,IEA)

flavin adenine dinucleotide binding (IBA,IDA)

pristanoyl-CoA oxidase activity (IBA,IDA,TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

alpha-linolenic acid metabolic pathway (IEA)

eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma (IEA)

fatty acid metabolic pathway (IEA)

unsaturated fatty acid biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.	Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Large-scale purification and further characterization of rat pristanoyl-CoA oxidase.	Van Veldhoven PP, etal., Eur J Biochem. 1994 Jun 15;222(3):795-801.
11.	Peroxisomal beta-oxidation of 2-methyl-branched acyl-CoA esters: stereospecific recognition of the 2S-methyl compounds by trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase.	Van Veldhoven PP, etal., FEBS Lett. 1996 Jun 10;388(1):80-4.
12.	Substrate specificities of rat liver peroxisomal acyl-CoA oxidases: palmitoyl-CoA oxidase (inducible acyl-CoA oxidase), pristanoyl-CoA oxidase (non-inducible acyl-CoA oxidase), and trihydroxycoprostanoyl-CoA oxidase.	Van Veldhoven PP, etal., J Biol Chem. 1992 Oct 5;267(28):20065-74.
13.	Rat pristanoyl-CoA oxidase. cDNA cloning and recognition of its C-terminal (SQL) by the peroxisomal-targeting signal 1 receptor.	Vanhooren JC, etal., Eur J Biochem 1996 Jul 15;239(2):302-9.

Additional References at PubMed

PMID:8993592	PMID:18614015	PMID:19946888	PMID:20178365

Genomics

Comparative Map Data

Acox3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	75,133,986 - 75,176,767 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	75,094,676 - 75,176,205 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	79,575,514 - 79,629,707 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	80,816,379 - 80,870,575 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	77,261,371 - 77,315,558 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	80,313,202 - 80,358,115 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	80,314,431 - 80,355,420 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	79,942,668 - 79,982,780 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	80,769,000 - 80,809,809 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	80,771,390 - 80,812,200 (-)	NCBI
Celera	14	74,065,866 - 74,104,532 (-)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

ACOX3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	8,355,305 - 8,440,723 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	8,366,282 - 8,440,723 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	8,368,009 - 8,442,450 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	8,418,909 - 8,493,352 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	8,486,518 - 8,560,499	NCBI
Celera	4	8,261,321 - 8,335,759 (-)	NCBI		Celera
Cytogenetic Map	4	p16.1	NCBI
HuRef	4	8,287,364 - 8,362,315 (-)	NCBI		HuRef
CHM1_1	4	8,366,366 - 8,440,788 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	8,337,453 - 8,420,469 (-)	NCBI		T2T-CHM13v2.0

Acox3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	35,740,293 - 35,772,397 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	35,740,384 - 35,772,696 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	35,582,981 - 35,614,208 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	35,583,040 - 35,615,352 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	35,925,709 - 35,956,450 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	35,899,921 - 35,930,662 (+)	NCBI		MGSCv36	mm8
Celera	5	33,056,108 - 33,087,085 (+)	NCBI		Celera
Cytogenetic Map	5	B3	NCBI
cM Map	5	18.32	NCBI

Acox3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	2,656,144 - 2,685,896 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955514	2,653,502 - 2,690,452 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACOX3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	4	8,569,231 - 8,654,531 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	4	8,432,788 - 8,506,499 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	8,432,788 - 8,494,157 (-)	Ensembl	panpan1.1		panPan2

ACOX3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	60,154,012 - 60,205,696 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	60,153,775 - 60,203,554 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	62,804,141 - 62,856,135 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	60,631,684 - 60,683,139 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	60,628,819 - 60,680,866 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	60,123,908 - 60,162,124 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	60,327,224 - 60,379,691 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	60,685,106 - 60,736,638 (-)	NCBI		UU_Cfam_GSD_1.0

Acox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	65,992,882 - 66,029,673 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	19,694,555 - 19,731,386 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936477	19,696,274 - 19,731,338 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACOX3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	2,716,918 - 2,770,801 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	2,716,913 - 2,756,221 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	4,391,443 - 4,418,723 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACOX3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	44,313,297 - 44,366,702 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666051	635,738 - 689,992 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acox3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624755	23,995,089 - 24,024,083 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624755	23,995,256 - 24,026,581 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Acox3
122 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	72
Count of miRNA genes:	65
Interacting mature miRNAs:	69
Transcripts:	ENSRNOT00000049798
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	37669719	82669719	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	37669719	82669719	Rat
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	37669719	82669719	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	37669719	82669719	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39057237	83368335	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39998251	75582726	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	40793460	98037301	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42262529	95023211	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	50023211	95023211	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	55147478	100147478	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	55624247	100624247	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	55624247	100624247	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	56631369	101631369	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	58184885	103184885	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	68757796	83368335	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	70053989	104886043	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	70053989	104886043	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	73415323	92554092	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	73415323	92554092	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	95876975	Rat

Markers in Region

RH142447

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	75,162,876 - 75,163,041 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	80,342,167 - 80,342,331	NCBI	Rnor6.0
Rnor_5.0	14	79,969,361 - 79,969,525	UniSTS	Rnor5.0
RGSC_v3.4	14	80,796,837 - 80,797,001	UniSTS	RGSC3.4
Celera	14	74,091,190 - 74,091,354	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	32	41	25	19	25	1	2	74	35	35	11	1
Low		11	16	16		16	7	9			6		7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005493022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC118993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB873101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB882963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB894292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC930510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC940372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC951701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X95188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000049798 ⟹ ENSRNOP00000042002

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	75,135,215 - 75,165,068 (-)	Ensembl
Rnor_6.0 Ensembl	14	80,314,431 - 80,355,420 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101859 ⟹ ENSRNOP00000081580

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	75,094,676 - 75,176,205 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110399 ⟹ ENSRNOP00000092103

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	75,133,996 - 75,176,205 (-)	Ensembl

RefSeq Acc Id:

NM_053339 ⟹ NP_445791

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	75,133,986 - 75,176,269 (-)	NCBI
Rnor_6.0	14	80,314,431 - 80,355,420 (-)	NCBI
Rnor_5.0	14	79,942,668 - 79,982,780 (-)	NCBI
RGSC_v3.4	14	80,769,000 - 80,809,809 (-)	RGD
Celera	14	74,065,866 - 74,104,532 (-)	RGD

Sequence:

show sequence

CGGGACCGACCGCAAGCTGGATCCGGACGGTGACAGTACCATGGGATCCTCATCGGAAAGAAGA
GACAGTGTTTTATGGTCAGACATCCCCAAGGGCCCCCTTAGTGCCTACCGAGCAAGAGCCTCCT
TCAATTCCAAGGAGCTGATGCTCTTCTGGGACGGCCAGGATGTACTCGACTTCAAGAAAACCAT
CTTCTCAACTTTGGAGAATGACCCTCTCTTCGCCCGCCCATTCGGGGCTGATCTGCCTCTGGAG
AAGGAACGAGAACTGAACTTCCTTCGCTGCAAGAGGGTCTTTGAGTATGGCTTCTTCAACGCAG
AGGACATGCTAAAGAACCCCCTGAAGATTCTAGTATTGATGAACTGCCTGGGCATGTACGACTG
GTCCCTGGCCAACAAATGTGTCCTCCACATGTTGGTTTTTGGATCTACAATTATCGGTTCTGGT
TCTGAGCACCATTTCAAGTACCTTGAGAAGATATATAACCTGGAGATTTTTGGCTGTTTCGCTC
TCACCGAACTGAGTCATGGGAGTAATACCAAGGCCATGAGAACAACAGCTCACTATGATCCTGC
TACTCAGGAATTCATCTTACATTCTCCAGATTTCGAGGCTGCCAAATTTTGGGTGGGCAACCTG
GGCAAGACCGCAACTCATGCGGTGGTGTTTGCCCAGCTGTACACGCCAGATGGCCAGTGCCGAG
GGCTGCATTCCTTCCTGGTGCAGATTCGGGACCCGAAGACCCTGCTTCCCATGCCAGGGGTGAT
GGTCGGTGACATGGGGAAGAAGTTGGGACAGAATGGCCTGGATAATGGATTCGCCATGTTCCAC
AAAGTTCGAATTCCTCGCCAGAACCTGCTGGACCGGACCGGGAATGTCACCTCTGAGGGACATT
ACCACACCCCCTTTAAGGATGTCCGGCAGCGTTTGGGGGCATCATTGGGCAGCCTGTCCTCGGG
ACGCATCTCCATCATTAGCATTTCTGTGGTCAACCTGAAGCTGGCTGTGATCATAGCTATCCGA
TTCTCAGCCACGCGGCGTCAGTTTGGACCCACAGATAAGGAAGAGATCCCTGTCCTCGAGTATC
CACTGCAGCAATGGCGCCTACTTCCATACCTGGCAGCTGCCTATGCCTTGGACCACTTCTCCAA
GACAATCTTCTTGGACCTGATAGAGCTACAGCGTGCCGGCAAAGTGGGGACCACAGTGACAGGC
AGGCAGAGCTCGGGACGGGAGATCCACGCACTAGCATCAGCGGGCAAGCCCCTAGCCTCATGGA
CAGCCCAGCGGGGAATTCAGGAGTGCCGTGAGGTTGTTGGGGGACACGGCTATCTAGCCATGAA
CCGGTTTGGCGAACTCAGAAATGACAACGATCCAAACTGTACCTATGAAGGCGACAACAATGTC
CTGCTGCAGCAGACCAGCAACTACCTGCTCAGCCTCCTGGAGCATCCTCTCCAAGACGGAGCTC
ACTTCACAAGCCCTCTCAAGACAGTGAACTTCCTGGAAGCCTACCCTGGAATCTTGGGCCAGAA
GTTCATGGCCTCCAGCAAGGCTGACTGGTTGGACTCAGAAGCCCCCCTGGCAGCCTACCGTTGG
CTTGTTTGCTACCTGCTCCGAGAGAGTCATCAGAGATACTGTCAAGAGAAAAAGTCCAGAGGCA
GTGACTTTGAAGCAAGGAACAACAGCCAGGTGTATGGCTGCCGGCCCCTGGCCCTGGCCTTCAT
GGAGCTCACTGTGATGCAGCGCTTCCACGAGCATACACACAGCTCTAGCGTGCCTCCATCTCTG
CGGACTGTGCTTGGACGGCTCAGCATGCTCTACGGCCTGTGGTGCCTGAGCCAACACACGGCCC
TGCTCTACCGAGGTGGCTACATCTCTGGGGAGCAAACAGGAAAAGCGATGGAGGATGCCATCCT
GATGCTGTGTGTGCAGCTGAAAGACGATGCGGTGGCCTTGGTGGACGCGATTGCCCCTTCTGAC
TTTGTCCTGGGCTCCCCAATTGGCAGAGCTGATGGCGAGCTCTATAAAAACCTGTGGGCAGCTG
TCCTGCAGCAGAGCGGTGTGCTGGAGCGTGCGGCCTGGTGGCCTGAGTTCACTGCCAACAAATC
TGTGGCCAACAGGCTGAAGTCCCAGCTGTAGACACAGTTGGAGGGGTGTCTGAGCAGGAGCAGC
CGATCCAGAGGCCTGGACCCAGACAATCAGACACCCACGCTGGAAGACACACTAAATCCTCTCC
TTGACTCTCGTCAGCCTGCGCGTACCCATCCCCAATGGGGTATTTGCAAGGAGTTTGCACAGTG
TGTCTCCCCGAGGGCCTTGGAATTTAACAAAGGATTTTGTAATGCTATCTCGGGGGCCCAGATA
GGAATGTAAAGGTCTGCTCAGGTAAACTTTGGGATCCGTGGAAGATTTTCAAGATGCTCTCTTC
TCTCTGCTGCTATCTGCYTCTTTTAACCTGGCGTGGGGTAACCATACGTCTGTTTACCGGCCAC
TTGCCACTCTGTACCCATGGACTGTCAGAATGTAATTTGAAGATTTTTTATATGAAAAAAAATG
TTTTATTAAGTCTTCGGTGGCACCAGAAGTTTCCACTGAG

hide sequence

RefSeq Acc Id:

XM_017599392 ⟹ XP_017454881

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	75,133,986 - 75,176,762 (-)	NCBI
Rnor_6.0	14	80,313,202 - 80,358,115 (-)	NCBI

Sequence:

show sequence

TCTTTCTGGCAGTCATATCGGGAAGTAGCTAAGAAATGAGGCAAGGGCAAACCCCTTTCTTTCT
CTGTAATGTGAAACCCTTCCAAATTTTAGCAGCCTGCCCACAAGGACAGTTTAATTTACCAAAG
TTTAGTTCCTCTCCTCAACATCCTGCAGTCTCATTGTCCCCTGGGTCCAACGCTGAGATGACCA
ACGAATTATCTGTCACACGCAGGTTTGGGGGTGTCTTAAGACCCAGGAACGGGGCCTTAGAGTT
GCAAAGAAGCTGGAGATCAAAGGTAGATGCCACCAAGAGATCTTGAAGTAAGCCAGGCCAGAGC
TGAGATAGATTGATTTGACAAGATCTTGTTAAGTCAGCCAGCCTGCCTTAAAACTTGTGAGCCT
CCTACCTCAGCTCCCACAGTGCTGGTATTGCAAGAGAAGTCTTGGGTTGGGGCAAGTCTTTAAC
CAGTTGCCATAGAACGAAATAAGGAGTGGAGCAATGGGATCCAAACTTGCTGATCCTGCCCTGA
GAATTGGAGACTTGAAGAGTGGAAGCAGGGTAGGGAGAGCTGAGAGAGAGTGGGGGGGATGAAT
GCACACTGGGAGGGTGAGAAGGATCTGGAACATGCTTTCTAAGTTTCCTCTACATGCTTACCCA
CTGCAACGACACCCTATCCTCCATGGAACTGACAGTCAAGAGTTCTCTTCCCACCCATCCAACT
CCACTGCCACAGCCATTGTAACTCTCACCCTTCCTCCTGCTCCTAAAACTGCTTGAAAATGTCC
CTTCTCACTCTTACTCCTGGGGGGAATCCTGAATGAGAATCAAATGAAGTTAATTTGTCAATAA
ACTCTTAACAAAACAGAGTCCAGAGACCCGGGGATGATTCTAGGTAACCTTCTCCTCTTAACAA
AATCACCACACTGCACAAGATTCCTTCCCTAAGGATGCCGGTACAGCAACTGCCACCAGCCTCA
GGGGGACACCACCCTTTTTATCTATCCTCAGGGGTAAGAACCCGTTTACCCAAAGAACCCCTAT
AACAATCCTTATACTCCTGATCTGTTCATGTGCCTATGATCCATCTTGGCTCACATATCCCAGA
TAGCAATTTAATTGTTCCCAAGGAAAACTTTAATTTTAGGGAGTCGGTCTCCCTACTGTTCATC
TAAACTGATAATTCCCAAGAAAGCAATGTTTTCCTCATGTTAATACATGAACACAACTTCTTAT
TAGCTGTGTTTGGACAACATTTGTGAGCTATACATGAATTCTGTCATGAATGGGTACCTTGTTA
CTCTCTAACTCTGGAAAAACAATAGCATGTATTCTTGCAGACCATTCTGGACGGCTCTACGAAC
TCAAGGACTCTTTGCGATGACAGAGTTCAAGCTGTAAATGCTGGTGGAGACTGAATGTCCATTC
AGACTGCTTAGCAAGGCAGAAGACATTTTCACGAGCTGTTCAGGCACTGTGAAGGTGACTGGGT
AGGAGTGCTTCTCTGATTCTGGAAACTTCTAGACTAGACTAGAGCAGAACATCCAGGATTGGTA
ACTGTTGTCTTCTGCCCATGCTGTCAGGTTCCCCTGCTTGGTGATGGGAGGCACTGTGACAACT
GCACACCAGGTAGGAAGGATGGTTTATCTGAGTATATTTGGTGTGTGTTTATGGTGGGAACAAT
TTCATTCTTTAGGCTGCCCATCCCTTCAGTCATTTCCCTTTGCTATCACTGCTACGATTTATTG
TTATTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTGTAATGTGTGCAGGCACAAATGTA
CCAGGGAATGCTCCTGGAGGTTGAAGGATCTCTTTCTGGAGTCAGTCCTCTCCACTGTGAGTTC
ATGAGGCATGTGCAGGATGCCCTACTTTCCAATAGAAAAGCCCCACTGACACCTGTGACTGAAA
GCGTGTTCTGAGTTAGAGCTATAAATGCAATAATTGGTACGGACAAAGTAGTTATTCAATTCAG
CAAACAGCTCCCAGCCCCGGCTGACAGAGGCAGAGTCCACTTGTGTCTGGTCCCAATGCTTCAA
ACCTGTCTCTGAAATAGAGTTCAGCATCTTTCTCTTTCCCCTAACGCCTTTTCCATCATTTTAG
TCCCTTTCAAAGGAAAACCGGCTTCCTCTAGCAAATAACCAAGTACCATTTGGTTCTTTGTCTG
CACTTGGCTTCAATCCCTACTCCACTCCACCCCCAGCAGAGCTTGAGACAAGATTCTTCGGAAA
TCTGCCAATCAGAGCACTATTTAGGAGTTCCTGGCAGGAAGGTCACCTGGGAATTCTGAGTAAA
GTGCACTTTAAAGGAGCCGCGGTCCAACTCTCCCGGAAGTGCTCCCAGAGCCATGAGAGGCCTG
GACCAAAACATGACATCTCTGCGGAAGGCGGTTTCTGAATAAGCCCGAGGCCTCTAACCAGGCA
GAAGGCGACCGGGATGAAATCCTTTATCTCCAAACCCGAAACCACATTGAGCTGAGCTCTTGGA
AGCGTCTGCGTTTCCCTGGCGACGACGCGGCGCAGCATGATGACGCAAGGCTTCAGGCAGCAGC
AACCCGAGTCAAGGGAGGGATGACGTCACGTTCCGGGATGGGGCCGGGGCGGCACCACCAACCT
GCTCCACCCTCAGAGGTCTGGACATTCCTGATCAACAGTGTTTGCCGGACCGACGCCAGTACTA
GGACCACGGACCGACCGCAAGCTGGATCCGGGCGGTGAGGACTTACCGGGCTCGGGAGATTCCA
GACAGAACAGGGTGACAGTACCATGGGATCCTCATCGGAAAGAAGAGACAGTGTTTTATGGTCA
GACATCCCCAAGGGCCCCCTTAGTGCCTACCGAGCAAGAGCCTCCTTCAATTCCAAGGAGCTGA
TGCTCTTCTGGGACGGCCAGGATGTACTCGACTTCAAGAAAACCATCTTCTCAACTTTGGAGAA
TGACCCTCTCTTCGCCCGCCCATTCGGGGCTGATCTGCCTCTGGAGAAGGAACGAGAACTGAAC
TTCCTTCGCTGCAAGAGGGTCTTTGAGTATGGCTTCTTCAACGCAGAGGACATGCTAAAGAACC
CCCTGAAGATTCTAGTATTGATGAACTGCCTGGGCATGTACGACTGGTCCCTGGCCAACAAATG
TGTCCTCCACATGTTGGTTTTTGGATCTACAATTATCGGTTCTGGTTCTGAGCACCATTTCAAG
TACCTTGAGAAGATATATAACCTGGAGATTTTTGGCTGTTTTGCTCTCACCGAACTGAGTCATG
GGAGTAATACCAAGGCCATGAGAACAACAGCTCACTATGATCCTGCTACCCAGGAATTCATCTT
ACATTCTCCAGATTTCGAGGCTGCCAAATTTTGGGTGGGCAACCTGGGCAAGACCGCAACTCAT
GCGGTGGTGTTTGCCCAGCTGTACACGCCAGATGGCCAGTGCCGAGGGCTGCATTCCTTCCTGG
TGCAGATTCGGGACCCGAAGACCCTGCTTCCCATGCCAGGGGTGATGGTCGGTGACATGGGGAA
GAAGTTGGGACAGAATGGCCTGGATAATGGATTCGCCATGTTCCACAAAGTTCGAATTCCTCGC
CAGAACCTGCTGGACCGGACCGGGAATGTCACCTCTGAGGGCACTTACAACACCCCCTTTAAGG
ATGTCCGGCAGCGTTTGGGGGCATCATTGGGCAGCCTGTCCTCGGGACGCATCTCCATCATTAG
CATTTCTGTGGTCAACCTGAAGCTGGCTGTGATCATAGCTATCCGATTCTCAGCCACGCGGCGT
CAGTTTGGACCCACAGATAAGGAAGAGATCCCTGTCCTCGAGTATCCACTGCAGCAATGGCGCC
TACTTCCATACCTGGCAGCTGCCTATGCCTTGGACCACTTCTCCAAGACAATCTTCTTGGACCT
GATAGAGCTACAGCGTGGCCGGCAAAGTGGGGACCACAGTGACAGGCAGGCAGAGCTCGGACGG
GAGATCCACGCACTAGCATCAGCGGGCAAGCCCCTAGCCTCATGGACAGCCCAGCGGGGAATTC
AGGAGTGCCGTGAGGCGTGTGGGGGACACGGCTATCTAGCCATGAACCGGTTTGGCGAACTCAG
AAATGACAACGATCCAAACTGTACCTATGAAGGTGACAACAATGTCCTGCTGCAGCAGACCAGC
AACTACCTGCTCAGCCTCCTGGAGCATCCTCTCCAAGACGGAGCTCACTTCACAAGCCCTCTCA
AGACAGTGAACTTCCTGGAAGCCTACCCTGGAATCTTGGGCCAGAAGTTCATGGCCTCCAGCAA
GGCTGACTGGTTGGACTCAGAAGCCCCCCTGGCAGCCTACCGTTGGCTTGTTTGCTACCTGCTC
CGAGAGAGTCATCAGAGATACTGTCAAGAGAAAAAGTCCAGAGGCAGTGACTTTGAAGCAAGGA
ACAACAGCCAGGTGTATGGCTGCCGGCCCCTGGCCCTGGCCTTCATGGAGCTCACTGTGATGCA
GCGCTTCCACGAGCATACACACAGCTCTAGCGTGCCTCCATCTCTGCGGACTGTGCTTGGACGG
CTCAGCATGCTCTACGGCCTGTGGTGCCTGAGCCAACACACGGCCCTGCTCTACCGAGGTGGCT
ACATCTCTGGGGAGCAAACAGGAAAAGCGATGGAGGATGCCATCCTGATGCTGTGTGTGCAGCT
GAAAGACGATGCGGTGGCCTTGGTGGACGCGATTGCCCCTTCTGACTTTGTCCTGGGCTCCCCA
ATTGGCAGAGCTGATGGCGAGCTCTATAAAAACCTGTGGGCAGCTGTCCTGCAGCAGAGCGGTG
TGCTGGAGCGTGCGGCCTGGTGGCCTGAGTTCACTGCCAACAAATCTGTGGCCAACAGGCTGAA
GTCCCAGCTGTAGACACAGTTGGAGGGGTGTCTGAGCAGGAGCAGCCGATCCAGAGGCCTGGAC
CCAGACAATCAGACACCCACGCTGGAAGACACACTAAATCCTCTCCTTGACTCTCGTCAGCCTG
CCGTACCCATCCCCAATGGGGTATTTGCAAGGAGTTTGCACAGTGTGTCTCCCCGAGGGCCTTG
GAATTTAACAAAGGATTTTGTAATGCTATCTCGGGGGCCCAGATAGGAATGTAAAGTTCTGCTC
AGGTAAACTTTGGGATCCGTGGAAGATTTTCAAGATGCTCTCTTCTCTCTGCTGCTATCTGCTT
CTTTAACCCTGCTGTGGGGTAACCATACGTCTGTTTACCTGCCACTTGCCACTCTGTACCATGG
ACTGTCAGAATGTAATTTGAAGATTTTTTATATGAAAAAAAATGTTTTATTAAGTCCTTCGGTG
GCACCAGAAGTTTCCACTGAGGAAAGTGCTCCCACAAAAGACATGCACCAGTTTGCTCACCACA
GACACCCCCATTGTGTCAGTAACTGCTTAGCTGTGGCTTTAGTCCTTTTGTTCCTAAAACAGGA
GGAATGCCCAGTGCCATCTGTTCCCGTCAAGTGTATCTCAGCAAATTCACACACGGCACGACCC
TGCCACACTGGCCGTAGCCAGATCTTGTGATCCTGAAAGGCACGTGATGCCATCCCTTCCTGCC
GTAGGGAGGAGCCCATACTGTTAGCATTTCTGACAAACTGTTCCGAGCCCCAGGTGCTTGCAGA
GCCTGAGAGCCTCTCTCTTCGACATCTGCTCTCGGTCAGCCACTACACCCTCCCCTGGGTCGGC
CCCTTCCCAGAGTCCCACCCCAGCTGAATGGGGGCCTGCCATCTTGAGTCTCTGTGGAACCTGA
GGGTCATGTGTTCACAGATGATGCCCTCCACCGGAATCTATGGCTTTTCCCAACAGTGACCACT
AGGTCCTCCCAGCTCTTGGGCTCCTTGCCCTCCAATCCTGCCAGGCAACAATCACCTCAGCCAC
CTGTTCGCCTCACCATACTTTTGTGTGGGAGCTTGGTTATCGTCCTGTCTGATTGGAGGCTGAC
TAGCATGTCACAGAAGTGCCCATGGTTAGAAGAGTGCTGCATTAAGATAAGTCACATGATTCCC
AGGGTCAGGCAGTCTGACTGCAGAGCGCCCCCTGGTGGCCGAGGTGCCAACAGATAACAAATTA
TTGAAAATGGCTCATTAGCTAGCTATAGCTTCTGAGGGGAAGGAGAGTCAGTTTTCTCTCAGGA
GTAGCCACTGGCAGGTTGATCGGGCTCCATTGCATGCCCACACACCCAAGAGCATATGTGCGGC
ACAGAGTGGACTTGATGGCTTTTGTTGTTGTTTTGTTATGTGTGCACATCTATGTTTTCATATC
TACCGGTTGGGTATGCCTTTGTCCCTGGGTAGGGACTGGCTCTCTGGACAAGTAGATGTCCTGT
TAGCCTGCAGACATCACATGACTCCCAAGAACGAATCGTGTATCCTGGTCCCTGCTCCTGTGCA
TGCACATTCCCCTCCTCTGTCCCGAGGCAGAGGCAAGTGGTGTGTGAGGCCTATGGGCAGAGGC
CACATTGTGAAGACAAACTTGTAAAGGTCCCATAAAAATGAAACATTTGTAAACAGTGGGAAAG
ACTTGAATAATTGCAATAAAGTGTTAAAATTGAA

hide sequence

RefSeq Acc Id:

XM_039092496 ⟹ XP_038948424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	75,133,986 - 75,175,407 (-)	NCBI

RefSeq Acc Id:

XM_039092497 ⟹ XP_038948425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	75,133,986 - 75,176,767 (-)	NCBI

RefSeq Acc Id:

XR_005493022

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	75,133,986 - 75,176,763 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_445791	(Get FASTA)	NCBI Sequence Viewer
	XP_017454881	(Get FASTA)	NCBI Sequence Viewer
	XP_038948424	(Get FASTA)	NCBI Sequence Viewer
	XP_038948425	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA64487	(Get FASTA)	NCBI Sequence Viewer
	CBF60600	(Get FASTA)	NCBI Sequence Viewer
	CBF65747	(Get FASTA)	NCBI Sequence Viewer
	CBF73150	(Get FASTA)	NCBI Sequence Viewer
	CBU85837	(Get FASTA)	NCBI Sequence Viewer
	CBU90618	(Get FASTA)	NCBI Sequence Viewer
	CBU96034	(Get FASTA)	NCBI Sequence Viewer
	EDM00057	(Get FASTA)	NCBI Sequence Viewer
	EDM00058	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000042002
	ENSRNOP00000042002.4
	ENSRNOP00000081580.1
	ENSRNOP00000092103
	ENSRNOP00000092103.1
GenBank Protein	Q63448	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_445791 ⟸ NM_053339

- UniProtKB:

A6IJZ3 (UniProtKB/TrEMBL), F1M9A7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGSSSERRDSVLWSDIPKGPLSAYRARASFNSKELMLFWDGQDVLDFKKTIFSTLENDPLFARP
FGADLPLEKERELNFLRCKRVFEYGFFNAEDMLKNPLKILVLMNCLGMYDWSLANKCVLHMLVF
GSTIIGSGSEHHFKYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQEFILHSPDFEA
AKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPGVMVGDMGKKLGQNGL
DNGFAMFHKVRIPRQNLLDRTGNVTSEGHYHTPFKDVRQRLGASLGSLSSGRISIISISVVNLK
LAVIIAIRFSATRRQFGPTDKEEIPVLEYPLQQWRLLPYLAAAYALDHFSKTIFLDLIELQRAG
KVGTTVTGRQSSGREIHALASAGKPLASWTAQRGIQECREVVGGHGYLAMNRFGELRNDNDPNC
TYEGDNNVLLQQTSNYLLSLLEHPLQDGAHFTSPLKTVNFLEAYPGILGQKFMASSKADWLDSE
APLAAYRWLVCYLLRESHQRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTH
SSSVPPSLRTVLGRLSMLYGLWCLSQHTALLYRGGYISGEQTGKAMEDAILMLCVQLKDDAVAL
VDAIAPSDFVLGSPIGRADGELYKNLWAAVLQQSGVLERAAWWPEFTANKSVANRLKSQL

hide sequence

RefSeq Acc Id:	XP_017454881 ⟸ XM_017599392
- Peptide Label:	isoform X1
- UniProtKB:	A6IJZ3 (UniProtKB/TrEMBL), F1M9A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSSSERRDSVLWSDIPKGPLSAYRARASFNSKELMLFWDGQDVLDFKKTIFSTLENDPLFARP FGADLPLEKERELNFLRCKRVFEYGFFNAEDMLKNPLKILVLMNCLGMYDWSLANKCVLHMLVF GSTIIGSGSEHHFKYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQEFILHSPDFEA AKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPGVMVGDMGKKLGQNGL DNGFAMFHKVRIPRQNLLDRTGNVTSEGTYNTPFKDVRQRLGASLGSLSSGRISIISISVVNLK LAVIIAIRFSATRRQFGPTDKEEIPVLEYPLQQWRLLPYLAAAYALDHFSKTIFLDLIELQRGR QSGDHSDRQAELGREIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNRFGELRNDNDPNC TYEGDNNVLLQQTSNYLLSLLEHPLQDGAHFTSPLKTVNFLEAYPGILGQKFMASSKADWLDSE APLAAYRWLVCYLLRESHQRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTH SSSVPPSLRTVLGRLSMLYGLWCLSQHTALLYRGGYISGEQTGKAMEDAILMLCVQLKDDAVAL VDAIAPSDFVLGSPIGRADGELYKNLWAAVLQQSGVLERAAWWPEFTANKSVANRLKSQL hide sequence

RefSeq Acc Id:

ENSRNOP00000042002 ⟸ ENSRNOT00000049798

RefSeq Acc Id:	XP_038948425 ⟸ XM_039092497
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038948424 ⟸ XM_039092496
- Peptide Label:	isoform X1
- UniProtKB:	A6IJZ3 (UniProtKB/TrEMBL), F1M9A7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000092103 ⟸ ENSRNOT00000110399

RefSeq Acc Id:

ENSRNOP00000081580 ⟸ ENSRNOT00000101859

Protein Domains

Acyl-CoA dehydrogenase/oxidase C-terminal Acyl-CoA oxidase C-terminal Acyl-CoA oxidase/dehydrogenase middle

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63448-F1-model_v2	AlphaFold	Q63448	1-700	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699389

Promoter ID:

EPDNEW_R9914

Type:

initiation region

Name:

Acox3_1

Description:

acyl-CoA oxidase 3, pristanoyl

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	80,355,468 - 80,355,528	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69245	AgrOrtholog
BioCyc Gene	G2FUF-15326	BioCyc
BioCyc Pathway	PWY-6061 [bile acid biosynthesis, neutral pathway]	BioCyc
Ensembl Genes	ENSRNOG00000008474	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000049798	ENTREZGENE
	ENSRNOT00000049798.4	UniProtKB/TrEMBL
	ENSRNOT00000101859.1	UniProtKB/TrEMBL
	ENSRNOT00000110399	ENTREZGENE
	ENSRNOT00000110399.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.110.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Butyryl-CoA Dehydrogenase, subunit A, domain 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	ACO	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_Oxase/DH_cen-dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_Oxase/DH_mid-dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_oxidase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AcylCo_DH-like_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AcylCo_DH/oxidase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AcylCoA_DH/oxidase_NM_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83522	UniProtKB/Swiss-Prot
NCBI Gene	83522	ENTREZGENE
PANTHER	PEROXISOMAL ACYL-COENZYME A OXIDASE 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10909	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ACOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_dh_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acyl-CoA_dh_M	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Acox3	PhenoGen
PIRSF	Acyl-CoA_oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008474	RatGTEx
Superfamily-SCOP	SSF47203	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56645	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AGJ0_RAT	UniProtKB/TrEMBL
	A0A8I6G857_RAT	UniProtKB/TrEMBL
	A6IJZ3	ENTREZGENE, UniProtKB/TrEMBL
	ACOX3_RAT	UniProtKB/Swiss-Prot
	F1M9A7	ENTREZGENE, UniProtKB/TrEMBL
	Q63448	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-07-28	Acox3	acyl-CoA oxidase 3, pristanoyl	Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Acox3	acyl-Coenzyme A oxidase 3, pristanoyl			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_function	oxidizes the CoA-esters of 2-methyl-branched fatty acids	724707

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)