Mir217 (microRNA 217) - Rat Genome Database

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Gene: Mir217 (microRNA 217) Rattus norvegicus
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Symbol: Mir217
Name: microRNA 217
RGD ID: 2325547
Description: Predicted to enable mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including mesonephric duct formation; negative regulation of gene expression; and positive regulation of cellular senescence. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; cellular response to lipopolysaccharide; and negative regulation of osteoblast differentiation. Orthologous to human MIR217 (microRNA 217); INTERACTS WITH aldehydo-D-glucose; atrazine; ceruletide.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-217; rno-mir-217
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,732,485 - 106,732,589 (+)NCBIGRCr8
mRatBN7.214102,531,505 - 102,531,609 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,531,505 - 102,531,609 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14106,859,726 - 106,859,830 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,096,341 - 108,096,445 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,568,757 - 104,568,861 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,119,529 - 113,119,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,119,529 - 113,119,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014112,809,662 - 112,809,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14101,431,634 - 101,431,738 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12624257   PMID:16381832   PMID:18762567   PMID:20403161   PMID:20439489   PMID:20548288   PMID:21628588   PMID:26891083   PMID:27521901   PMID:28339007   PMID:30417525   PMID:31173187  
PMID:32311345   PMID:32626929   PMID:33064238   PMID:33283391   PMID:33378037   PMID:35963157   PMID:36041665  


Genomics

Comparative Map Data
Mir217
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,732,485 - 106,732,589 (+)NCBIGRCr8
mRatBN7.214102,531,505 - 102,531,609 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,531,505 - 102,531,609 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14106,859,726 - 106,859,830 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,096,341 - 108,096,445 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,568,757 - 104,568,861 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,119,529 - 113,119,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,119,529 - 113,119,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014112,809,662 - 112,809,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14101,431,634 - 101,431,738 (+)NCBICelera
Cytogenetic Map14q22NCBI
MIR217
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,982,967 - 55,983,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,982,967 - 55,983,076 (-)EnsemblGRCh38hg38GRCh38
GRCh37256,210,102 - 56,210,211 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36256,063,605 - 56,063,714 (-)NCBINCBI36Build 36hg18NCBI36
Celera256,050,481 - 56,050,590 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,945,116 - 55,945,225 (-)NCBIHuRef
CHM1_1256,140,034 - 56,140,143 (-)NCBICHM1_1
T2T-CHM13v2.0255,979,867 - 55,979,976 (-)NCBIT2T-CHM13v2.0
Mir217
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,713,728 - 28,713,835 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1128,713,728 - 28,713,835 (+)EnsemblGRCm39 Ensembl
GRCm381128,763,728 - 28,763,835 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,763,728 - 28,763,835 (+)EnsemblGRCm38mm10GRCm38
MGSCv371128,663,728 - 28,663,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1131,135,189 - 31,135,296 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.23NCBI
MIR217
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,754,566 - 56,754,647 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1056,754,566 - 56,754,647 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1056,710,952 - 56,711,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01057,759,472 - 57,759,553 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11057,459,123 - 57,459,204 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,738,695 - 57,738,776 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01058,030,279 - 58,030,360 (-)NCBIUU_Cfam_GSD_1.0
MIR217-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl385,341,255 - 85,341,361 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1385,341,255 - 85,341,361 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,065,707 - 90,065,813 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:8423
Count of gene targets:5257
Count of transcripts:5707
Interacting mature miRNAs:rno-miR-217-3p, rno-miR-217-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system hemolymphoid system nervous system reproductive system respiratory system
High
Medium 1
Low 4 3 5 3
Below cutoff 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000053641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl14102,531,505 - 102,531,609 (+)Ensembl
Rnor_6.0 Ensembl14113,119,529 - 113,119,633 (+)Ensembl
RefSeq Acc Id: NR_031929
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814106,732,485 - 106,732,589 (+)NCBI
mRatBN7.214102,531,505 - 102,531,609 (+)NCBI
Rnor_6.014113,119,529 - 113,119,633 (+)NCBI
Rnor_5.014112,809,662 - 112,809,766 (+)NCBI
Celera14101,431,634 - 101,431,738 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325547 AgrOrtholog
BioCyc Gene G2FUF-14685 BioCyc
Ensembl Genes ENSRNOG00000035518 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053641 ENTREZGENE
miRBase MI0000956 ENTREZGENE
NCBI Gene 100314056 ENTREZGENE
PhenoGen Mir217 PhenoGen
RatGTEx ENSRNOG00000035518 RatGTEx
RNAcentral URS000075BEE6 RNACentral
  URS000075C6FD RNACentral
  URS000075E622 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir217  microRNA 217  Mir217  microRNA mir-217  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir217  microRNA mir-217      Symbol and Name status set to provisional 70820 PROVISIONAL