Gene: Purb (purine rich element binding protein B) Rattus norvegicus
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Symbol: Purb
Name: purine rich element binding protein B
Description: ENCODES a protein that exhibits purine-rich negative regulatory element binding; single-stranded DNA binding; translation repressor activity, mRNA regulatory element binding; INVOLVED IN negative regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN nucleus; DNA replication factor A complex (ortholog); INTERACTS WITH bisphenol A; cocaine; dibutyl phthalate
AGR Description: Exhibits purine-rich negative regulatory element binding activity, single-stranded DNA binding activity, and translation repressor activity, mRNA regulatory element binding; involved in negative regulation of transcription, DNA-templated; localizes to the nucleus; orthologous to human PURB (purine rich element binding protein B).
Merged Description: Exhibits purine-rich negative regulatory element binding activity, single-stranded DNA binding activity, and translation repressor activity, mRNA regulatory element binding; involved in negative regulation of transcription, DNA-templated; localizes to the nucleus; orthologous to human PURB (purine rich element binding protein B); INTERACTS WITH bisphenol A; cocaine; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: pur-beta; purine-rich element-binding protein B; transcription factor Pur-beta; transcriptional activator protein Pur-beta
Orthologs:
Homo sapiens (human) : PURB (purine rich element binding protein B)  HGNC  Alliance
Mus musculus (house mouse) : Purb (purine rich element binding protein B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Purb (purine rich element binding protein B)
Pan paniscus (bonobo/pygmy chimpanzee) : PURB (purine rich element binding protein B)
Canis lupus familiaris (dog) : PURB (purine rich element binding protein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Purb (purine rich element binding protein B)
Sus scrofa (pig) : PURB (purine rich element binding protein B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01486,736,876 - 86,739,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01480,371,417 - 80,373,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,230,346 - 87,232,805 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1480,223,695 - 80,226,154 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Purb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559465
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.