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Gene: Dok7 (docking protein 7) Rattus norvegicus
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Symbol: Dok7
Name: docking protein 7
Description: Predicted to have phosphatidylinositol binding activity and protein kinase binding activity. Predicted to be involved in neuromuscular junction development; positive regulation of protein tyrosine kinase activity; and receptor clustering. Predicted to localize to the mitochondrion; neuromuscular junction; and nucleoplasm. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10. Orthologous to human DOK7 (docking protein 7); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH bisphenol A; tetrachloromethane; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: downstream of tyrosine kinase 7; LOC305448; protein Dok-7; RGD1566416; similar to hypothetical protein A930013K19
Orthologs:
Homo sapiens (human) : DOK7 (docking protein 7)  HGNC  Alliance
Mus musculus (house mouse) : Dok7 (docking protein 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dok7 (docking protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : DOK7 (docking protein 7)
Canis lupus familiaris (dog) : DOK7 (docking protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dok7 (docking protein 7)
Sus scrofa (pig) : DOK7 (docking protein 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01480,925,409 - 80,963,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,926,654 - 80,958,478 (-)Ensembl
Rnor_5.01481,615,342 - 81,647,642 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,308,034 - 81,339,858 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1474,593,247 - 74,625,071 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dok7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566416
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.