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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ccdc88a | Rat | (S)-nicotine | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Nicotine results in increased expression of CCDC88A mRNA | CTD | PMID:17456735 | Ccdc88a | Rat | 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of CCDC88A mRNA | CTD | PMID:21983209 | Ccdc88a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCDC88A promoter] | CTD | PMID:19654925 | Ccdc88a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CCDC88A mRNA | CTD | PMID:34747641 | Ccdc88a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCDC88A mRNA | CTD | PMID:32109520 and PMID:33387578 | Ccdc88a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCDC88A mRNA | CTD | PMID:21570461 and PMID:24680724 | Ccdc88a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCDC88A mRNA | CTD | PMID:22298810 | Ccdc88a | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | Ccdc88a | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CCDC88A mRNA | CTD | PMID:30047161 | Ccdc88a | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CCDC88A mRNA | CTD | PMID:36843608 | Ccdc88a | Rat | acrolein | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of CCDC88A mRNA | CTD | PMID:32699268 | Ccdc88a | Rat | aflatoxin B1 | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CCDC88A gene | CTD | PMID:27153756 | Ccdc88a | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of CCDC88A intron | CTD | PMID:30157460 | Ccdc88a | Rat | all-trans-retinoic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CCDC88A mRNA | CTD | PMID:21934132 | Ccdc88a | Rat | alpha-pinene | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of CCDC88A mRNA | CTD | PMID:32699268 | Ccdc88a | Rat | benzo[a]pyrene | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC88A mRNA | CTD | PMID:20064835 | Ccdc88a | Rat | benzo[a]pyrene | affects methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CCDC88A intron | CTD | PMID:30157460 | Ccdc88a | Rat | benzo[a]pyrene | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CCDC88A mRNA | CTD | PMID:22228805 | Ccdc88a | Rat | benzo[a]pyrene | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC88A mRNA | CTD | PMID:19770486 | Ccdc88a | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Ccdc88a | Rat | bisphenol A | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | bisphenol A results in increased expression of CCDC88A mRNA | CTD | PMID:27685785 | Ccdc88a | Rat | bisphenol A | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CCDC88A gene | CTD | PMID:31601247 | Ccdc88a | Rat | bisphenol A | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CCDC88A gene | CTD | PMID:31601247 | Ccdc88a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCDC88A mRNA | CTD | PMID:30816183 | Ccdc88a | Rat | cadmium atom | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Cadmium results in decreased expression of CCDC88A mRNA | CTD | PMID:21120746 | Ccdc88a | Rat | cadmium atom | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC88A mRNA | CTD | PMID:35301059 | Ccdc88a | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of CCDC88A mRNA | CTD | PMID:33453195 | Ccdc88a | Rat | cadmium dichloride | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC88A mRNA | CTD | PMID:35301059 | Ccdc88a | Rat | cadmium dichloride | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of CCDC88A mRNA | CTD | PMID:24982889 | Ccdc88a | Rat | caffeine | affects phosphorylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of CCDC88A protein | CTD | PMID:35688186 | Ccdc88a | Rat | chlorpyrifos | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of CCDC88A mRNA | CTD | PMID:37019170 | Ccdc88a | Rat | cisplatin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CCDC88A mRNA | CTD | PMID:27392435 | Ccdc88a | Rat | clobetasol | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Clobetasol results in decreased expression of CCDC88A mRNA | CTD | PMID:27462272 | Ccdc88a | Rat | clofibrate | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Clofibrate results in increased expression of CCDC88A mRNA | CTD | PMID:17585979 | Ccdc88a | Rat | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of CCDC88A mRNA | CTD | PMID:17898221 | Ccdc88a | Rat | copper(II) sulfate | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of CCDC88A mRNA | CTD | PMID:19549813 | Ccdc88a | Rat | corosolic acid | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | corosolic acid results in increased expression of CCDC88A mRNA | CTD | PMID:37939859 | Ccdc88a | Rat | crocidolite asbestos | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of CCDC88A mRNA | CTD | PMID:29279043 | Ccdc88a | Rat | dioxygen | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of CCDC88A mRNA | CTD | PMID:24205000 | Ccdc88a | Rat | dioxygen | affects methylation | ISO | Ccdc88a (Mus musculus) | 6480464 | Oxygen deficiency affects the methylation of CCDC88A promoter | CTD | PMID:24205000 | Ccdc88a | Rat | dorsomorphin | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc88a | Rat | doxorubicin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CCDC88A mRNA | CTD | PMID:29803840 | Ccdc88a | Rat | doxorubicin | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Doxorubicin co-treated with Folic Acid] results in increased expression of CCDC88A mRNA | CTD | PMID:28608983 | Ccdc88a | Rat | enzyme inhibitor | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CCDC88A protein | CTD | PMID:23301498 | Ccdc88a | Rat | ethanol | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Ethanol results in decreased expression of CCDC88A mRNA | CTD | PMID:29018328 | Ccdc88a | Rat | folic acid | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Doxorubicin co-treated with Folic Acid] results in increased expression of CCDC88A mRNA | CTD | PMID:28608983 | Ccdc88a | Rat | formaldehyde | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CCDC88A mRNA | CTD | PMID:20655997 and PMID:27664576 | Ccdc88a | Rat | fulvestrant | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CCDC88A gene | CTD | PMID:31601247 | Ccdc88a | Rat | hydrogen peroxide | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of CCDC88A mRNA | CTD | PMID:18951874 | Ccdc88a | Rat | ivermectin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CCDC88A protein | CTD | PMID:32959892 | Ccdc88a | Rat | leflunomide | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | leflunomide results in decreased expression of CCDC88A mRNA | CTD | PMID:28988120 | Ccdc88a | Rat | maneb | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA | CTD | PMID:22563483 | Ccdc88a | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CCDC88A mRNA | CTD | PMID:30047161 | Ccdc88a | Rat | miconazole | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Miconazole results in decreased expression of CCDC88A mRNA | CTD | PMID:27462272 | Ccdc88a | Rat | nicotine | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Nicotine results in increased expression of CCDC88A mRNA | CTD | PMID:17456735 | Ccdc88a | Rat | ozone | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA more ... | CTD | PMID:32699268 | Ccdc88a | Rat | paracetamol | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Acetaminophen affects the expression of CCDC88A mRNA | CTD | PMID:17562736 | Ccdc88a | Rat | paracetamol | affects expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Acetaminophen affects the expression of CCDC88A mRNA | CTD | PMID:25458485 | Ccdc88a | Rat | paraquat | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA | CTD | PMID:22563483 | Ccdc88a | Rat | paraquat | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Paraquat results in increased expression of CCDC88A mRNA | CTD | PMID:22563483 | Ccdc88a | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CCDC88A mRNA | CTD | PMID:27153767 | Ccdc88a | Rat | phenylmercury acetate | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC88A mRNA | CTD | PMID:27188386 | Ccdc88a | Rat | pirinixic acid | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCDC88A mRNA | CTD | PMID:19710929 | Ccdc88a | Rat | pyridaben | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | pyridaben results in increased expression of CCDC88A mRNA | CTD | PMID:22563483 | Ccdc88a | Rat | quercetin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CCDC88A mRNA | CTD | PMID:21632981 | Ccdc88a | Rat | quercetin | affects phosphorylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Quercetin affects the phosphorylation of CCDC88A protein | CTD | PMID:35688186 | Ccdc88a | Rat | resveratrol | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CCDC88A mRNA | CTD | PMID:23557933 | Ccdc88a | Rat | SB 431542 | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc88a | Rat | serpentine asbestos | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Asbestos and Serpentine results in increased expression of CCDC88A mRNA | CTD | PMID:21148743 | Ccdc88a | Rat | sodium arsenate | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | sodium arsenate results in increased expression of CCDC88A mRNA | CTD | PMID:21795629 | Ccdc88a | Rat | sodium arsenite | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | sodium arsenite results in increased expression of CCDC88A mRNA | CTD | PMID:32068019 | Ccdc88a | Rat | succimer | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of CCDC88A mRNA | CTD | PMID:21641980 | Ccdc88a | Rat | sunitinib | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CCDC88A mRNA | CTD | PMID:31533062 | Ccdc88a | Rat | temozolomide | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of CCDC88A mRNA | CTD | PMID:31758290 | Ccdc88a | Rat | testosterone | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Testosterone results in decreased expression of CCDC88A mRNA | CTD | PMID:33359661 | Ccdc88a | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CCDC88A mRNA | CTD | PMID:34492290 | Ccdc88a | Rat | titanium dioxide | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CCDC88A mRNA | CTD | PMID:23557971 | Ccdc88a | Rat | toluene | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Toluene results in increased expression of CCDC88A mRNA | CTD | PMID:28245982 | Ccdc88a | Rat | torcetrapib | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | torcetrapib results in increased expression of CCDC88A mRNA | CTD | PMID:23228038 | Ccdc88a | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of CCDC88A mRNA | CTD | PMID:33387578 | Ccdc88a | Rat | trichostatin A | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CCDC88A mRNA | CTD | PMID:26272509 | Ccdc88a | Rat | trichostatin A | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC88A mRNA | CTD | PMID:27188386 | Ccdc88a | Rat | triphenyl phosphate | affects expression | ISO | CCDC88A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CCDC88A mRNA | CTD | PMID:37042841 | Ccdc88a | Rat | triptonide | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | triptonide results in decreased expression of CCDC88A mRNA | CTD | PMID:33045310 | Ccdc88a | Rat | valproic acid | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CCDC88A gene | CTD | PMID:29154799 | Ccdc88a | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of CCDC88A mRNA | CTD | PMID:29427782 | Ccdc88a | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of CCDC88A mRNA | CTD | PMID:29427782 | Ccdc88a | Rat | valproic acid | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Valproic Acid affects the expression of CCDC88A mRNA | CTD | PMID:17292431 | Ccdc88a | Rat | valproic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CCDC88A mRNA | CTD | PMID:23179753 | Ccdc88a | Rat | valproic acid | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CCDC88A mRNA | CTD | PMID:29154799 | Ccdc88a | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of CCDC88A mRNA | CTD | PMID:19015723 | |