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Gene: CCDC88A (coiled-coil domain containing 88A) Homo sapiens
Symbol: CCDC88A
Name: coiled-coil domain containing 88A
Description: Exhibits several functions, including G-protein alpha-subunit binding activity; enzyme binding activity; and growth factor receptor binding activity. Involved in several processes, including lamellipodium assembly; maintenance of protein location in plasma membrane; and positive regulation of organelle organization. Localizes to several cellular components, including Golgi apparatus; lamellipodium; and microtubule organizing center.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: akt phosphorylation enhancer; AKT-phosphorylation enhancer; APE; coiled-coil domain-containing protein 88A; DKFZp686D0630; g alpha-interacting vesicle-associated protein; Galpha-interacting vesicle-associated protein; girders of actin filament; girders of actin filaments; girdin; GIV; GRDN; G{alpha}-interacting vesicle-associated protein; HkRP1; Hook-related protein 1; KIAA1212; PEHO; PEHOL
Mus musculus (house mouse) : Ccdc88a (coiled coil domain containing 88A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccdc88a (coiled coil domain containing 88A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccdc88a (coiled-coil domain containing 88A)
Pan paniscus (bonobo/pygmy chimpanzee) : CCDC88A (coiled-coil domain containing 88A)
Canis lupus familiaris (dog) : CCDC88A (coiled-coil domain containing 88A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccdc88a (coiled-coil domain containing 88A)
Sus scrofa (pig) : CCDC88A (coiled-coil domain containing 88A)
Chlorocebus sabaeus (African green monkey) : CCDC88A (coiled-coil domain containing 88A)
Heterocephalus glaber (naked mole-rat) : Ccdc88a (coiled-coil domain containing 88A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl255,287,842 - 55,419,895 (-)EnsemblGRCh38hg38GRCh38
GRCh38255,287,817 - 55,419,856 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37255,514,978 - 55,647,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,368,482 - 55,500,467 (-)NCBINCBI36hg18NCBI36
Build 34255,426,630 - 55,558,614NCBI
Celera255,355,473 - 55,487,467 (-)NCBI
Cytogenetic Map2p16.1NCBI
HuRef255,250,032 - 55,382,309 (-)NCBIHuRef
CHM1_1255,444,983 - 55,577,340 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CCDC88A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347801
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.