Gene: Lif (LIF, interleukin 6 family cytokine) Rattus norvegicus
Analyze
Symbol: Lif
Name: LIF, interleukin 6 family cytokine
Description: ENCODES a protein that exhibits leukemia inhibitory factor receptor binding; cytokine activity (ortholog); growth factor activity (ortholog); INVOLVED IN animal organ regeneration; astrocyte differentiation; negative regulation of angiogenesis; PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH brain ischemia; congestive heart failure; Stroke; FOUND IN extracellular space; cytosol (ortholog); INTERACTS WITH (+)-pilocarpine; 1,3-dinitrobenzene; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cholinergic neuronal differentiation factor; leukemia inhibitory factor; leukemia inhibitory factor (cholinergic differentiation factor)
Orthologs:
Homo sapiens (human) : LIF (LIF, interleukin 6 family cytokine)  HGNC  Alliance
Mus musculus (house mouse) : Lif (leukemia inhibitory factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lif (LIF, interleukin 6 family cytokine)
Pan paniscus (bonobo/pygmy chimpanzee) : LIF (LIF, interleukin 6 family cytokine)
Canis lupus familiaris (dog) : LIF (LIF, interleukin 6 family cytokine)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lif (LIF, interleukin 6 family cytokine)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01484,482,652 - 84,500,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01485,163,603 - 85,181,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,887,856 - 84,890,630 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11484,907,000 - 84,909,775 (+)NCBI
Celera1478,044,967 - 78,047,741 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lif
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620865
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE