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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | H2az2 | Rat | (+)-catechin | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of H2AZ2 mRNA | CTD | PMID:24763279 | H2az2 | Rat | (S)-nicotine | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Nicotine results in decreased expression of H2AZ2 mRNA | CTD | PMID:17456735 | H2az2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of H2AZ2 mRNA | CTD | PMID:22206623 | H2az2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of H2AZ2 mRNA | CTD | PMID:17942748 | H2az2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | H2az2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of H2AZ2 mRNA | CTD | PMID:17555576 | H2az2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of H2AZ2 mRNA | CTD | PMID:17942748 | H2az2 | Rat | 17beta-estradiol | affects expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Estradiol affects the expression of H2AZ2 mRNA | CTD | PMID:22574217 | H2az2 | Rat | 17beta-estradiol | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of H2AZ2 mRNA | CTD | PMID:17404688 | H2az2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of H2AZ2 mRNA | CTD | PMID:17942748 | H2az2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of H2AZ2 mRNA | CTD | PMID:34747641 | H2az2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of H2AZ2 mRNA | CTD | PMID:19770486 | H2az2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of H2AZ2 mRNA | CTD | PMID:28628672 | H2az2 | Rat | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of H2AZ2 mRNA | CTD | PMID:19162173 | H2az2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of H2AZ2 protein | CTD | PMID:34186270 | H2az2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of H2AZ2 mRNA | CTD | PMID:36041667 | H2az2 | Rat | actinomycin D | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of H2AZ2 protein | CTD | PMID:38460933 | H2az2 | Rat | antirheumatic drug | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of H2AZ2 mRNA | CTD | PMID:24449571 | H2az2 | Rat | azathioprine | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of H2AZ2 mRNA | CTD | PMID:22623647 | H2az2 | Rat | benzo[a]pyrene | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of H2AZ2 mRNA | CTD | PMID:21632981 | H2az2 | Rat | benzo[a]pyrene | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of H2AZ2 mRNA | CTD | PMID:20127859 | H2az2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of H2AZ2 mRNA | CTD | PMID:25181051 | H2az2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of H2AZ2 mRNA | CTD | PMID:36041667 | H2az2 | Rat | bisphenol A | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of H2AZ2 protein | CTD | PMID:34186270 | H2az2 | Rat | bisphenol A | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of H2AZ2 mRNA | CTD | PMID:32156529 | H2az2 | Rat | bisphenol A | affects expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of H2AZ2 mRNA | CTD | PMID:30903817 | H2az2 | Rat | bisphenol AF | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of H2AZ2 protein | CTD | PMID:34186270 | H2az2 | Rat | Bisphenol B | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of H2AZ2 protein | CTD | PMID:34186270 | H2az2 | Rat | bisphenol F | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of H2AZ2 mRNA | CTD | PMID:28628672 | H2az2 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of H2AZ2 mRNA | CTD | PMID:36041667 | H2az2 | Rat | butanal | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of H2AZ2 mRNA | CTD | PMID:26079696 | H2az2 | Rat | cadmium atom | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of H2AZ2 mRNA | CTD | PMID:35301059 | H2az2 | Rat | cadmium dichloride | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of H2AZ2 mRNA | CTD | PMID:35301059 | H2az2 | Rat | cadmium sulfate | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | cadmium sulfate affects the reaction [MTF1 affects the expression of H2AZ2 mRNA] | CTD | PMID:16221973 | H2az2 | Rat | captan | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Captan results in decreased expression of H2AZ2 mRNA | CTD | PMID:31558096 | H2az2 | Rat | carbamazepine | affects expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of H2AZ2 mRNA | CTD | PMID:25979313 | H2az2 | Rat | carbon nanotube | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | H2az2 | Rat | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of H2AZ2 mRNA | CTD | PMID:18668222 | H2az2 | Rat | clofibrate | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of H2AZ2 mRNA | CTD | PMID:23811191 | H2az2 | Rat | cobalt dichloride | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of H2AZ2 mRNA | CTD | PMID:19320972 | H2az2 | Rat | copper atom | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of H2AZ2 mRNA | CTD | PMID:20971185 | H2az2 | Rat | copper(0) | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of H2AZ2 mRNA | CTD | PMID:20971185 | H2az2 | Rat | copper(II) sulfate | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of H2AZ2 mRNA | CTD | PMID:19549813 | H2az2 | Rat | coumestrol | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AZ2 mRNA | CTD | PMID:19167446 | H2az2 | Rat | coumestrol | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of H2AZ2 mRNA | CTD | PMID:19167446 | H2az2 | Rat | cyclosporin A | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of H2AZ2 mRNA | CTD | PMID:20106945 more ... | H2az2 | Rat | cyclosporin A | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of H2AZ2 mRNA | CTD | PMID:19770486 | H2az2 | Rat | deguelin | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | deguelin results in decreased expression of H2AZ2 mRNA | CTD | PMID:33512557 | H2az2 | Rat | dexamethasone | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of H2AZ2 mRNA | CTD | PMID:28628672 | H2az2 | Rat | diallyl trisulfide | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | diallyl trisulfide results in decreased expression of H2AZ2 mRNA | CTD | PMID:34995734 | H2az2 | Rat | dibutyl phthalate | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of H2AZ2 mRNA | CTD | PMID:21266533 | H2az2 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of H2AZ2 mRNA | CTD | PMID:21266533 | H2az2 | Rat | dicrotophos | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of H2AZ2 mRNA | CTD | PMID:28302478 | H2az2 | Rat | diethyl maleate | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | diethyl maleate results in increased expression of H2AZ2 mRNA | CTD | PMID:33545341 | H2az2 | Rat | dioxygen | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of H2AZ2 mRNA | CTD | PMID:30529165 | H2az2 | Rat | disodium selenite | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of H2AZ2 mRNA | CTD | PMID:18175754 | H2az2 | Rat | Enterolactone | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AZ2 mRNA | CTD | PMID:19167446 | H2az2 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of H2AZ2 mRNA | CTD | PMID:34044035 | H2az2 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of H2AZ2 mRNA | CTD | PMID:24136188 | H2az2 | Rat | folic acid | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of H2AZ2 mRNA | CTD | PMID:21867686 | H2az2 | Rat | folic acid | multiple interactions | ISO | H2az2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of H2AZ2 mRNA | CTD | PMID:22206623 | H2az2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of H2AZ2 mRNA | CTD | PMID:22061828 | H2az2 | Rat | indometacin | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of H2AZ2 mRNA | CTD | PMID:28628672 | H2az2 | Rat | ivermectin | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of H2AZ2 protein | CTD | PMID:32959892 | H2az2 | Rat | methylmercury chloride | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of H2AZ2 mRNA | CTD | PMID:28001369 | H2az2 | Rat | methylparaben | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | methylparaben results in decreased expression of H2AZ2 mRNA | CTD | PMID:31745603 | H2az2 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of H2AZ2 protein | CTD | PMID:24675778 | H2az2 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of H2AZ2 protein | CTD | PMID:26558463 | H2az2 | Rat | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of H2AZ2 mRNA | CTD | PMID:24136188 | H2az2 | Rat | nicotine | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Nicotine results in decreased expression of H2AZ2 mRNA | CTD | PMID:17456735 | H2az2 | Rat | Nutlin-3 | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of H2AZ2 protein | CTD | PMID:38460933 | H2az2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of H2AZ2 mRNA | CTD | PMID:25729387 | H2az2 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | Oxaliplatin results in decreased expression of H2AZ2 mRNA | CTD | PMID:25729387 | H2az2 | Rat | paracetamol | affects expression | ISO | H2az2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of H2AZ2 mRNA | CTD | PMID:17562736 | H2az2 | Rat | paracetamol | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of H2AZ2 mRNA | CTD | PMID:38614205 | H2az2 | Rat | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of H2AZ2 mRNA | CTD | PMID:19162173 | H2az2 | Rat | picoxystrobin | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of H2AZ2 mRNA | CTD | PMID:33512557 | H2az2 | Rat | progesterone | multiple interactions | ISO | H2AZ2 (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of H2AZ2 mRNA | CTD | PMID:17404688 | H2az2 | Rat | propiconazole | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | propiconazole results in decreased expression of H2AZ2 mRNA | CTD | PMID:21278054 | H2az2 | Rat | sodium arsenate | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of H2AZ2 mRNA | CTD | PMID:30953684 | H2az2 | Rat | sodium arsenite | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of H2AZ2 mRNA | CTD | PMID:28595984 | H2az2 | Rat | sodium arsenite | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of H2AZ2 mRNA | CTD | PMID:36209798 | H2az2 | Rat | sodium arsenite | affects expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of H2AZ2 mRNA | CTD | PMID:34032870 | H2az2 | Rat | sodium arsenite | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of H2AZ2 mRNA | CTD | PMID:38568856 | H2az2 | Rat | sodium dichromate | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | sodium bichromate results in increased expression of H2AZ2 mRNA | CTD | PMID:31558096 | H2az2 | Rat | sodium fluoride | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of H2AZ2 protein | CTD | PMID:27548804 | H2az2 | Rat | sunitinib | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of H2AZ2 mRNA | CTD | PMID:31533062 | H2az2 | Rat | tamoxifen | affects expression | ISO | H2az2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of H2AZ2 mRNA | CTD | PMID:17555576 | H2az2 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of H2AZ2 mRNA | CTD | PMID:15336504 | H2az2 | Rat | tetrachloromethane | decreases expression | ISO | H2az2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of H2AZ2 mRNA | CTD | PMID:31919559 | H2az2 | Rat | tolcapone | affects binding | EXP | | 6480464 | Tolcapone binds to H2AZ2 protein | CTD | PMID:19783845 | H2az2 | Rat | topotecan | affects response to substance | ISO | H2AZ2 (Homo sapiens) | 6480464 | H2AZ2 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | H2az2 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of H2AZ2 mRNA | CTD | PMID:25729387 | H2az2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of H2AZ2 mRNA | CTD | PMID:25729387 | H2az2 | Rat | tungsten | increases expression | ISO | H2az2 (Mus musculus) | 6480464 | Tungsten results in increased expression of H2AZ2 mRNA | CTD | PMID:30912803 | H2az2 | Rat | valproic acid | affects expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of H2AZ2 mRNA | CTD | PMID:25979313 | H2az2 | Rat | valproic acid | increases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of H2AZ2 mRNA | CTD | PMID:23179753 more ... | H2az2 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of H2AZ2 mRNA | CTD | PMID:23034163 | H2az2 | Rat | zinc sulfate | decreases expression | ISO | H2AZ2 (Homo sapiens) | 6480464 | Zinc Sulfate results in decreased expression of H2AZ2 mRNA | CTD | PMID:12756304 | |