(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of SLIT2 protein CTD PMID:20153733 (+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of SLIT2 protein CTD PMID:20153733 1,1-dichloroethene decreases expression ISO RGD:735484 6480464 vinylidene chloride results in decreased expression of SLIT2 mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression ISO RGD:735484 6480464 1, 2-Dimethylhydrazine results in increased expression of SLIT2 mRNA CTD PMID:22206623 17beta-estradiol increases expression ISO RGD:733021 6480464 Estradiol results in increased expression of SLIT2 mRNA CTD PMID:19484750 17beta-estradiol increases expression ISO RGD:735484 6480464 Estradiol results in increased expression of SLIT2 mRNA CTD PMID:19484750 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735484 6480464 Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to SLIT2 promoter] CTD PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735484 6480464 Tetrachlorodibenzodioxin results in increased expression of SLIT2 mRNA CTD PMID:32553695 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLIT2 mRNA CTD PMID:32109520 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733021 6480464 Tetrachlorodibenzodioxin results in increased expression of SLIT2 mRNA CTD PMID:21296121 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-methylcholine affects expression ISO RGD:733021 6480464 beta-methylcholine affects the expression of SLIT2 mRNA CTD PMID:21179406 3,4-methylenedioxymethamphetamine increases expression ISO RGD:735484 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SLIT2 mRNA CTD PMID:20188158 3-methylcholanthrene decreases expression ISO RGD:735484 6480464 Methylcholanthrene results in decreased expression of SLIT2 mRNA CTD PMID:20713471 3-Nitrobenzanthrone increases expression ISO RGD:733021 6480464 3-nitrobenzanthrone results in increased expression of SLIT2 mRNA CTD PMID:34036453 4,4'-sulfonyldiphenol increases expression ISO RGD:735484 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SLIT2 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide decreases expression ISO RGD:735484 6480464 Fenretinide results in decreased expression of SLIT2 mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide increases expression ISO RGD:735484 6480464 Fenretinide results in increased expression of SLIT2 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine increases expression ISO RGD:733021 6480464 Decitabine results in increased expression of SLIT2 mRNA CTD PMID:19100240 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLIT2 mRNA CTD PMID:30047161 7,12-dimethyltetraphene increases expression ISO RGD:735484 6480464 9 more ... CTD PMID:32553695 acetaldehyde affects expression ISO RGD:735484 6480464 Acetaldehyde affects the expression of SLIT2 mRNA CTD PMID:22634333 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SLIT2 mRNA CTD PMID:31881176 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of SLIT2 mRNA CTD PMID:28959563 acrylamide decreases expression ISO RGD:735484 6480464 Acrylamide results in decreased expression of SLIT2 mRNA CTD PMID:29261810 afimoxifene multiple interactions ISO RGD:733021 6480464 afimoxifene inhibits the reaction [Estrogens results in decreased expression of SLIT2 mRNA] CTD PMID:21233418 aflatoxin B1 affects expression ISO RGD:733021 6480464 Aflatoxin B1 affects the expression of SLIT2 protein CTD PMID:20106945 aflatoxin B1 affects methylation ISO RGD:733021 6480464 Aflatoxin B1 affects the methylation of SLIT2 intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:733021 6480464 Aflatoxin B1 results in decreased methylation of SLIT2 gene CTD PMID:27153756 Aflatoxin B2 alpha decreases methylation ISO RGD:733021 6480464 aflatoxin B2 results in decreased methylation of SLIT2 intron CTD PMID:30157460 all-trans-retinoic acid increases expression ISO RGD:733021 6480464 Tretinoin results in increased expression of SLIT2 mRNA CTD PMID:23724009 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of SLIT2 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLIT2 mRNA CTD PMID:16483693 aristolochic acid A decreases expression ISO RGD:733021 6480464 aristolochic acid I results in decreased expression of SLIT2 mRNA, aristolochic acid I results in decreased expression of SLIT2 protein CTD PMID:30381256 , PMID:33212167 aristolochic acid A multiple interactions ISO RGD:733021 6480464 aristolochic acid I inhibits the reaction [SLIT2 protein results in increased activity of RAC1 protein] more ... CTD PMID:30381256 atrazine decreases expression ISO RGD:733021 6480464 Atrazine results in decreased expression of SLIT2 mRNA CTD PMID:22378314 belinostat increases expression ISO RGD:733021 6480464 belinostat results in increased expression of SLIT2 mRNA CTD PMID:26272509 benzo[a]pyrene multiple interactions ISO RGD:735484 6480464 Benzo(a)pyrene affects the reaction [AHR protein binds to SLIT2 promoter] CTD PMID:19654925 benzo[a]pyrene increases methylation ISO RGD:733021 6480464 Benzo(a)pyrene results in increased methylation of SLIT2 5' UTR, Benzo(a)pyrene results in increased methylation of SLIT2 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:735484 6480464 Benzo(a)pyrene metabolite results in increased expression of SLIT2 mRNA CTD PMID:32553695 benzo[a]pyrene affects methylation ISO RGD:733021 6480464 Benzo(a)pyrene affects the methylation of SLIT2 intron CTD PMID:30157460 benzo[a]pyrene increases methylation ISO RGD:735484 6480464 Benzo(a)pyrene results in increased methylation of SLIT2 intron CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:733021 6480464 Benzo(a)pyrene results in decreased expression of SLIT2 mRNA CTD PMID:21871943 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:733021 6480464 7 more ... CTD PMID:19150397 more ... benzo[e]pyrene decreases methylation ISO RGD:733021 6480464 benzo(e)pyrene results in decreased methylation of SLIT2 intron CTD PMID:30157460 bisphenol A decreases expression ISO RGD:733021 6480464 bisphenol A results in decreased expression of SLIT2 mRNA CTD PMID:22576693 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SLIT2 mRNA CTD PMID:30816183 , PMID:34947998 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of SLIT2 gene CTD PMID:28505145 bisphenol A increases expression ISO RGD:735484 6480464 bisphenol A results in increased expression of SLIT2 mRNA CTD PMID:25594700 more ... bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLIT2 mRNA CTD PMID:25181051 bisphenol F increases expression ISO RGD:735484 6480464 bisphenol F results in increased expression of SLIT2 mRNA CTD PMID:30951980 cadmium atom multiple interactions ISO RGD:735484 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLIT2 mRNA CTD PMID:36114956 cadmium dichloride multiple interactions ISO RGD:735484 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLIT2 mRNA CTD PMID:36114956 carbamazepine affects expression ISO RGD:733021 6480464 Carbamazepine affects the expression of SLIT2 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO RGD:735484 6480464 Nanotubes, Carbon results in decreased expression of SLIT2 mRNA CTD PMID:25554681 choline multiple interactions ISO RGD:735484 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLIT2 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO RGD:735484 6480464 chromium hexavalent ion affects the expression of SLIT2 mRNA CTD PMID:28472532 cisplatin multiple interactions ISO RGD:733021 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of SLIT2 mRNA CTD PMID:21858171 copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of SLIT2 mRNA CTD PMID:26033743 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of SLIT2 mRNA CTD PMID:26033743 copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of SLIT2 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of SLIT2 mRNA CTD PMID:26033743 crocidolite asbestos affects expression ISO RGD:733021 6480464 Asbestos, Crocidolite affects the expression of SLIT2 mRNA CTD PMID:17331233 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of SLIT2 mRNA CTD PMID:26577399 cyclosporin A increases expression ISO RGD:733021 6480464 Cyclosporine results in increased expression of SLIT2 mRNA CTD PMID:20106945 cyproconazole increases expression ISO RGD:735484 6480464 cyproconazole results in increased expression of SLIT2 mRNA CTD PMID:22045034 cytarabine decreases expression ISO RGD:733021 6480464 Cytarabine results in decreased expression of SLIT2 mRNA CTD PMID:21198554 deguelin decreases expression ISO RGD:733021 6480464 deguelin results in decreased expression of SLIT2 mRNA CTD PMID:33512557 dexamethasone decreases expression ISO RGD:735484 6480464 Dexamethasone results in decreased expression of SLIT2 mRNA CTD PMID:22733784 dexamethasone decreases expression ISO RGD:733021 6480464 Dexamethasone results in decreased expression of SLIT2 mRNA CTD PMID:25047013 dibutyl phthalate decreases expression ISO RGD:735484 6480464 Dibutyl Phthalate results in decreased expression of SLIT2 mRNA CTD PMID:17361019 , PMID:21266533 dimethylarsinous acid increases expression ISO RGD:733021 6480464 dimethylarsinous acid results in increased expression of SLIT2 mRNA CTD PMID:23487506 dorsomorphin multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:735484 6480464 Doxorubicin results in decreased expression of SLIT2 mRNA CTD PMID:25896364 doxorubicin decreases expression ISO RGD:733021 6480464 Doxorubicin results in decreased expression of SLIT2 mRNA CTD PMID:29803840 elemental selenium decreases expression ISO RGD:733021 6480464 Selenium results in decreased expression of SLIT2 mRNA CTD PMID:19244175 enniatin decreases expression ISO RGD:733021 6480464 enniatins results in decreased expression of SLIT2 mRNA CTD PMID:36016515 ethanol decreases expression ISO RGD:735484 6480464 Ethanol results in decreased expression of SLIT2 mRNA CTD PMID:29018328 ethanol increases expression ISO RGD:735484 6480464 Ethanol results in increased expression of SLIT2 mRNA CTD PMID:30319688 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of SLIT2 mRNA CTD PMID:30307764 flusilazole affects expression ISO RGD:735484 6480464 flusilazole affects the expression of SLIT2 mRNA CTD PMID:22634333 folic acid multiple interactions ISO RGD:735484 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLIT2 mRNA CTD PMID:20938992 folic acid decreases expression ISO RGD:733021 6480464 Folic Acid results in decreased expression of SLIT2 mRNA CTD PMID:21867686 fulvestrant increases methylation ISO RGD:733021 6480464 Fulvestrant results in increased methylation of SLIT2 gene CTD PMID:31601247 furan decreases expression EXP 6480464 furan results in decreased expression of SLIT2 mRNA CTD PMID:25539665 furan increases expression EXP 6480464 furan results in increased expression of SLIT2 mRNA CTD PMID:27387713 furan decreases methylation EXP 6480464 furan results in decreased methylation of SLIT2 gene CTD PMID:27387713 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SLIT2 mRNA CTD PMID:22061828 hexaconazole increases expression ISO RGD:735484 6480464 hexaconazole results in increased expression of SLIT2 mRNA CTD PMID:22045034 ketoconazole increases expression ISO RGD:733021 6480464 Ketoconazole results in increased expression of SLIT2 mRNA CTD PMID:36621641 L-methionine multiple interactions ISO RGD:735484 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SLIT2 mRNA CTD PMID:20938992 lithium atom increases expression EXP 6480464 Lithium results in increased expression of SLIT2 protein CTD PMID:20153733 lithium atom decreases expression EXP 6480464 Lithium results in decreased expression of SLIT2 protein CTD PMID:20153733 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of SLIT2 protein CTD PMID:20153733 lithium hydride decreases expression EXP 6480464 Lithium results in decreased expression of SLIT2 protein CTD PMID:20153733 mercury dibromide increases expression ISO RGD:733021 6480464 mercuric bromide results in increased expression of SLIT2 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 methapyrilene decreases methylation ISO RGD:733021 6480464 Methapyrilene results in decreased methylation of SLIT2 intron CTD PMID:30157460 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of SLIT2 mRNA CTD PMID:30047161 methylisothiazolinone increases expression ISO RGD:733021 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of SLIT2 mRNA CTD PMID:31629900 methylmercury chloride increases expression ISO RGD:733021 6480464 methylmercuric chloride results in increased expression of SLIT2 mRNA CTD PMID:28001369 methylmercury chloride decreases expression ISO RGD:735484 6480464 methylmercuric chloride results in decreased expression of SLIT2 mRNA CTD PMID:29261810 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of SLIT2 mRNA CTD PMID:25972201 Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of SLIT2 mRNA CTD PMID:21515302 N-acetyl-1,4-benzoquinone imine affects response to substance ISO RGD:733021 6480464 SLIT2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 nickel sulfate increases expression ISO RGD:733021 6480464 nickel sulfate results in increased expression of SLIT2 mRNA CTD PMID:22714537 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of SLIT2 mRNA CTD PMID:19944214 O-methyleugenol decreases expression ISO RGD:733021 6480464 methyleugenol results in decreased expression of SLIT2 mRNA CTD PMID:32234424 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SLIT2 mRNA CTD PMID:25729387 p-chloromercuribenzoic acid increases expression ISO RGD:733021 6480464 p-Chloromercuribenzoic Acid results in increased expression of SLIT2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 panobinostat multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:733021 6480464 panobinostat results in increased expression of SLIT2 mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:733021 6480464 Acetaminophen affects the expression of SLIT2 mRNA CTD PMID:25458485 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SLIT2 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:733021 6480464 Acetaminophen results in increased expression of SLIT2 mRNA CTD PMID:29067470 PD 0325901 multiple interactions ISO RGD:733021 6480464 [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of SLIT2 mRNA CTD PMID:25119042 PD 0325901 decreases expression ISO RGD:733021 6480464 mirdametinib results in decreased expression of SLIT2 mRNA CTD PMID:25119042 phenylmercury acetate increases expression ISO RGD:733021 6480464 Phenylmercuric Acetate results in increased expression of SLIT2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 pirinixic acid increases expression ISO RGD:735484 6480464 pirinixic acid results in increased expression of SLIT2 mRNA CTD PMID:17426115 piroxicam multiple interactions ISO RGD:733021 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of SLIT2 mRNA CTD PMID:21858171 pyrimidifen decreases expression ISO RGD:733021 6480464 pyrimidifen results in decreased expression of SLIT2 mRNA CTD PMID:33512557 rotenone decreases expression ISO RGD:733021 6480464 Rotenone results in decreased expression of SLIT2 mRNA CTD PMID:33512557 SB 431542 multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom decreases expression ISO RGD:733021 6480464 Selenium results in decreased expression of SLIT2 mRNA CTD PMID:19244175 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of SLIT2 mRNA CTD PMID:32721576 silicon dioxide increases methylation ISO RGD:733021 6480464 Silicon Dioxide results in increased methylation of SLIT2 promoter CTD PMID:34973136 silver atom decreases expression ISO RGD:735484 6480464 Silver results in decreased expression of SLIT2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:735484 6480464 Silver results in decreased expression of SLIT2 mRNA CTD PMID:27131904 sodium arsenite increases expression ISO RGD:733021 6480464 sodium arsenite results in increased expression of SLIT2 mRNA CTD PMID:22714537 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of SLIT2 mRNA CTD PMID:30047161 temozolomide increases expression ISO RGD:733021 6480464 Temozolomide results in increased expression of SLIT2 mRNA CTD PMID:31758290 Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of SLIT2 mRNA CTD PMID:21515302 testosterone decreases expression ISO RGD:733021 6480464 Testosterone results in decreased expression of SLIT2 mRNA CTD PMID:33359661 thapsigargin decreases expression ISO RGD:733021 6480464 Thapsigargin results in decreased expression of SLIT2 mRNA CTD PMID:22378314 thifluzamide decreases expression ISO RGD:733021 6480464 thifluzamide results in decreased expression of SLIT2 mRNA CTD PMID:33512557 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SLIT2 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of SLIT2 mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:733021 6480464 trichostatin A results in increased expression of SLIT2 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 triptonide increases expression ISO RGD:735484 6480464 triptonide results in increased expression of SLIT2 mRNA CTD PMID:33045310 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SLIT2 mRNA CTD PMID:21515302 tunicamycin decreases expression ISO RGD:733021 6480464 Tunicamycin results in decreased expression of SLIT2 mRNA CTD PMID:22378314 , PMID:29453283 urethane increases expression ISO RGD:733021 6480464 Urethane results in increased expression of SLIT2 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:735484 6480464 Valproic Acid affects the expression of SLIT2 mRNA CTD PMID:17292431 , PMID:22045034 valproic acid decreases expression ISO RGD:735484 6480464 Valproic Acid results in decreased expression of SLIT2 mRNA CTD PMID:29261810 valproic acid affects expression ISO RGD:733021 6480464 Valproic Acid affects the expression of SLIT2 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:733021 6480464 Valproic Acid results in increased expression of SLIT2 mRNA CTD PMID:23179753 more ... vorinostat increases expression ISO RGD:733021 6480464 vorinostat results in increased expression of SLIT2 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:733021 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT2 mRNA CTD PMID:27188386 zearalenone decreases expression ISO RGD:733021 6480464 Zearalenone results in decreased expression of SLIT2 mRNA CTD PMID:28965971