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Gene: Prom1 (prominin 1) Rattus norvegicus
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Symbol: Prom1
Name: prominin 1
Description: Predicted to have actinin binding activity; cadherin binding activity; and cholesterol binding activity. Predicted to be involved in several processes, including glomerular epithelial cell differentiation; photoreceptor cell maintenance; and retina morphogenesis in camera-type eye. Predicted to localize to several cellular components, including endoplasmic reticulum-Golgi intermediate compartment; extracellular vesicle; and photoreceptor outer segment membrane. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12 and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD133; fudenine; MGC156650; Prom; prominin; prominin-1
Orthologs:
Homo sapiens (human) : PROM1 (prominin 1)  HGNC  Alliance
Mus musculus (house mouse) : Prom1 (prominin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prom1 (prominin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PROM1 (prominin 1)
Canis lupus familiaris (dog) : PROM1 (prominin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prom1 (prominin 1)
Sus scrofa (pig) : PROM1 (prominin 1)
Chlorocebus sabaeus (African green monkey) : PROM1 (prominin 1)
Heterocephalus glaber (naked mole-rat) : Prom1 (prominin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01471,532,321 - 71,637,400 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1471,533,063 - 71,637,417 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01471,573,130 - 71,668,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41472,122,986 - 72,230,453 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11472,125,409 - 72,232,843 (+)NCBI
Celera1465,949,815 - 66,052,606 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prom1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69367
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.