Rdh7 (retinol dehydrogenase 7) - Rat Genome Database

Name: Rdh7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Rdh7 (retinol dehydrogenase 7) Rattus norvegicus

Analyze

No known orthologs.

Symbol:

Rdh7

Name:

retinol dehydrogenase 7

RGD ID:

631370

Description:

Predicted to enable NAD-retinol dehydrogenase activity. Predicted to be involved in retinol metabolic process. Predicted to be located in endoplasmic reticulum. Orthologous to human RDH16 (retinol dehydrogenase 16); PARTICIPATES IN retinoic acid metabolic pathway; retinol metabolic pathway; INTERACTS WITH N-nitrosodimethylamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical gene supported by NM_133543; LOC360420; MGC108523; MGC112590; Rdh3; retinol dehydrogenase 3; retinol dehydrogenase type III; RGD1307178; RODH I; RODH III; RoDH(III)

RGD Orthologs

Alliance Genes

More Info

homologs ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Other homologs ²				less info ...
Homo sapiens (human):	RDH16 (retinol dehydrogenase 16)	HGNC	Ensembl, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Rdh7 (retinol dehydrogenase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Homo sapiens (human):	RDH16 (retinol dehydrogenase 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Danio rerio (zebrafish):	rdh5 (retinol dehydrogenase 5 (11-cis/9-cis))	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|sonicParanoid)
Danio rerio (zebrafish):	rdh1 (retinol dehydrogenase 1)	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|sonicParanoid)
Drosophila melanogaster (fruit fly):	CG8888	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|sonicParanoid)
Caenorhabditis elegans (roundworm):	dhs-20	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	63,676,016 - 63,689,375 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	7	63,675,579 - 63,689,392 (-)	Ensembl
Rnor_6.0	7	71,125,358 - 71,164,014 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	71,297,358 - 71,533,937 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	67,818,370 - 67,831,729 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	7	60,810,166 - 60,822,127 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

N-nitrosodimethylamine (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

retinol metabolic process (IBA,IEA)

steroid metabolic process (IBA)

Cellular Component

endoplasmic reticulum (IEA)

intracellular membrane-bounded organelle (IBA)

Molecular Function

NAD-retinol dehydrogenase activity (IBA)

oxidoreductase activity (IBA)

steroid dehydrogenase activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

retinoic acid metabolic pathway (TAS)

retinol metabolic pathway (IEA)

References

References - curated


1.	Chai X, etal., Gene 1996 Mar 9;169(2):219-22.
2.	Chai X, etal., J Biol Chem 1995 Feb 24;270(8):3900-4.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	MGD data from the GO Consortium
5.	Napoli JL Biochim Biophys Acta. 2012 Jan;1821(1):152-67. Epub 2011 May 19.
6.	Pipeline to import KEGG annotations from KEGG into RGD
7.	RGD automated data pipeline
8.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334

Genomics

Position Markers

D7Rat45

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,902,608 - 63,902,784 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,351,952 - 71,352,127	NCBI	Rnor6.0
Rnor_5.0	7	71,522,185 - 71,522,360	UniSTS	Rnor5.0
RGSC_v3.4	7	68,056,925 - 68,057,251	RGD	RGSC3.4
RGSC_v3.4	7	68,056,997 - 68,057,172	UniSTS	RGSC3.4
RGSC_v3.1	7	68,077,655 - 68,077,981	RGD
Celera	7	61,034,295 - 61,034,470	UniSTS
FHH x ACI Map	7	33.46	RGD
FHH x ACI Map	7	33.46	UniSTS
Cytogenetic Map	7	q22	UniSTS

D7Rat75

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,768,981 - 63,769,114 (+)	MAPPER	mRatBN7.2
mRatBN7.2	7	63,773,357 - 63,773,500 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,222,726 - 71,222,868	NCBI	Rnor6.0
Rnor_6.0	7	71,218,350 - 71,218,482	NCBI	Rnor6.0
Rnor_5.0	7	71,390,350 - 71,390,482	UniSTS	Rnor5.0
Rnor_5.0	7	71,394,726 - 71,394,868	UniSTS	Rnor5.0
RGSC_v3.4	7	67,912,562 - 67,912,695	RGD	RGSC3.4
RGSC_v3.4	7	67,916,939 - 67,917,081	UniSTS	RGSC3.4
RGSC_v3.4	7	67,916,938 - 67,917,081	RGD	RGSC3.4
RGSC_v3.4	7	67,912,563 - 67,912,695	UniSTS	RGSC3.4
RGSC_v3.1	7	67,933,292 - 67,933,425	RGD
Celera	7	60,906,045 - 60,906,187	UniSTS
Celera	7	60,901,669 - 60,901,801	UniSTS
FHH x ACI Map	7	33.38	RGD
FHH x ACI Map	7	33.38	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH144391

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,814,272 - 63,814,395 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,263,990 - 71,264,112	NCBI	Rnor6.0
Rnor_5.0	7	71,435,990 - 71,436,112	UniSTS	Rnor5.0
RGSC_v3.4	7	67,957,852 - 67,957,974	UniSTS	RGSC3.4
Celera	7	60,946,935 - 60,947,057	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH136995

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,908,905 - 63,909,086 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,358,268 - 71,358,448	NCBI	Rnor6.0
Rnor_5.0	7	71,528,340 - 71,528,520	UniSTS	Rnor5.0
RGSC_v3.4	7	68,065,868 - 68,066,048	UniSTS	RGSC3.4
Celera	7	61,040,584 - 61,040,764	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH130952

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,906,389 - 63,906,575 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,355,752 - 71,355,937	NCBI	Rnor6.0
Rnor_5.0	7	71,525,824 - 71,526,009	UniSTS	Rnor5.0
RGSC_v3.4	7	68,061,791 - 68,061,976	UniSTS	RGSC3.4
Celera	7	61,038,076 - 61,038,261	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH134392

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,676,163 - 63,676,343 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,125,506 - 71,125,685	NCBI	Rnor6.0
Rnor_5.0	7	71,297,506 - 71,297,685	UniSTS	Rnor5.0
RGSC_v3.4	7	67,818,518 - 67,818,697	UniSTS	RGSC3.4
Celera	7	60,810,314 - 60,810,493	UniSTS
Cytogenetic Map	7	q22	UniSTS

AU044268

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,906,539 - 63,906,674 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,355,902 - 71,356,036	NCBI	Rnor6.0
Rnor_5.0	7	71,525,974 - 71,526,108	UniSTS	Rnor5.0
RGSC_v3.4	7	68,061,941 - 68,062,075	UniSTS	RGSC3.4
Celera	7	61,038,226 - 61,038,360	UniSTS
Cytogenetic Map	7	q22	UniSTS

BE106097

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	63,714,099 - 63,714,311 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	71,163,151 - 71,163,362	NCBI	Rnor6.0
Rnor_5.0	7	71,335,151 - 71,335,362	UniSTS	Rnor5.0
RGSC_v3.4	7	67,856,449 - 67,856,660	UniSTS	RGSC3.4
Celera	7	60,846,847 - 60,847,058	UniSTS
Cytogenetic Map	7	q22	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	26737401	63902784	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
1641885	Alcrsp9	Alcohol response QTL 9			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	7	24099606	69099606	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	37960569	82960569	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	34293282	79293282	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	19654317	84928080	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	42787314	87787314	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	29409683	84928080	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	24751841	69751841	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	44867533	89867533	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	34293282	79293282	Rat
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	21921195	66921195	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	43228750	88228750	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	47251783	65728867	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	29409683	74409683	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	31112832	76112832	Rat

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC088090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ209576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ209710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U18762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U33501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_133543 ⟹ NP_598227

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	63,676,016 - 63,689,375 (-)	NCBI
Rnor_6.0	7	71,125,358 - 71,164,014 (-)	NCBI
Rnor_5.0	7	71,297,358 - 71,533,937 (-)	NCBI
RGSC_v3.4	7	67,818,370 - 67,831,729 (-)	RGD
Celera	7	60,810,166 - 60,822,127 (-)	RGD

Sequence:

show sequence

CCCTGAAGCCTACACCATCCTGCGTGAGCAGATGCCCGTCTCATTTTGACTCAGAGTCTGTCCC
TCTGCTTGTCTTCTACAAGCCATGTGGCTCTACCTGCTGGCACTGGTGGGCCTGTGGAACCTCC
TGCGCTTGTTCAGGGAGAGGAAGGTGGTGAGCCATCTCCAAGACAAGTATGTCTTCATCACGGG
CTGTGACTCAGGCTTTGGGAACCTGCTGGCCAGACAGCTGGACAGGAGAGGCATGAGGGTGCTG
GCTGCATGTCTGACTGAGAAGGGAGCCGAGCAGCTGAGGAGCAAGACATCGGACAGGCTGGAGA
CAGTGATCCTTGATGTCACCAAGACAGAGAGTATTGTGGCAGCCACTCAGTGGGTGAAGGAGCG
AGTTGGGAACAGAGGACTCTGGGGCCTGGTCAACAATGCTGGCATCTCTGTCCCCATGGGTCCC
AATGAGTGGATGAGAAAAAAGGACTTTGCAAGTGTGCTGGATGTGAACCTGTTGGGCGTCATCG
AGGTGACTCTGAACATGCTGCCCTTAGTAAGGAAGGCAAGGGGCCGCGTGGTCAACATCGCCAG
CACCATGGGCCGAATGTCTCTCCTTGGTGGTGGTTACTGCATCTCCAAGTATGGTGTAGAGGCC
TTCTCAGACTCCCTCAGGAGGGAGCTCACCTACTTTGGGGTGAAGGTGGCTATTATAGAGCCTG
GTGGGTTCAAGACCAATGTCACTAATATGGAGAGGCTATCAGACAACCTGAAGAAGCTGTGGGA
CCAGGCCACTGAGGAGGTCAAGGAGATCTACGGCGAGAAGTTTCGGGACTCCTATATGAAAGCA
ATGGAGTCACTGGTGAACATGTGCTCAGGGGACCTGTCTCTGGTAACCGACTGCATGGAGCACG
CCCTGACTTCCTGTCACCCTCGCACCCGGTACTCAGCTGGTTGGGATGCCAAGTTCTTCTACCT
CCCCATGAGCTACCTTCCCACCTTTCTTTCGGATGCCGTAATCTACTGGGGCTCTGTAAAGCCT
GCCCGAGCCCTGTGAATCTGCACATGTGTGCAGACTTGGGGAAGTAAGGCGGGTGGAGGGAGAT
AACAATGTGGGGTCCATTGTTCACCATACTCATTAAAATAATTCTGCTTCCGTACTACTCAAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598227	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB07995	(Get FASTA)	NCBI Sequence Viewer
	AAB07997	(Get FASTA)	NCBI Sequence Viewer
	AAH88090	(Get FASTA)	NCBI Sequence Viewer
	AAH98650	(Get FASTA)	NCBI Sequence Viewer
	EDM16445	(Get FASTA)	NCBI Sequence Viewer
	P55006	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_598227 ⟸ NM_133543
- Peptide Label:	precursor
- UniProtKB:	P55006 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEK GAEQLRSKTSDRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISVPMGPNEWMRKK DFASVLDVNLLGVIEVTLNMLPLVRKARGRVVNIASTMGRMSLLGGGYCISKYGVEAFSDSLRR ELTYFGVKVAIIEPGGFKTNVTNMERLSDNLKKLWDQATEEVKEIYGEKFRDSYMKAMESLVNM CSGDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLSDAVIYWGSVKPARAL hide sequence

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0U1RVK8-F1-model_v2	AlphaFold	A0A0U1RVK8	1-266	view protein structure
AF-P55006-F1-model_v2	AlphaFold	P55006	1-317	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

Visual

CSV

TAB

Printer

Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

Visual

CSV

TAB

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631370	AgrOrtholog
BioCyc Gene	G2FUF-33716	BioCyc
Ensembl Genes	ENSRNOG00000004391	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005875	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000062303	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005875	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000065232	UniProtKB/TrEMBL
InterPro	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sc_DH/Rdtase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SDR_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:360420	UniProtKB/Swiss-Prot
NCBI Gene	360420	ENTREZGENE
Pfam	adh_short	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Rdh7	PhenoGen
PRINTS	GDHRDH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SDRFAMILY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ADH_SHORT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0U1RVK8_RAT	UniProtKB/TrEMBL
	F1LVY2_RAT	UniProtKB/TrEMBL
	P55006	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	P50169	UniProtKB/Swiss-Prot
	Q4KMB6	UniProtKB/Swiss-Prot
	Z4YNE9	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Rdh7	retinol dehydrogenase 7	Rdh3	retinol dehydrogenase type III	Symbol and Name updated	1299863	APPROVED
2005-02-23	Rdh3	retinol dehydrogenase type III	RGD1307178_predicted	hypothetical gene supported by NM_133543 (predicted)	Data Merged	737654	APPROVED
2005-01-20	RGD1307178_predicted	hypothetical gene supported by NM_133543 (predicted)	LOC360420_predicted		Symbol updated	1331353	APPROVED
2005-01-12	LOC360420_predicted	hypothetical gene supported by NM_133543 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_homology	shows 97.8% identity with RoDH(I) and 82.3% identity with RoDH(II)	633812

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)