Os9 (OS9, endoplasmic reticulum lectin) - Rat Genome Database

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Gene: Os9 (OS9, endoplasmic reticulum lectin) Rattus norvegicus
Analyze
Symbol: Os9
Name: OS9, endoplasmic reticulum lectin
RGD ID: 1359574
Description: Enables protease binding activity. Involved in protein targeting. Located in endoplasmic reticulum lumen. Orthologous to human OS9 (OS9 endoplasmic reticulum lectin); PARTICIPATES IN hypoxia inducible factor pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: amplified in osteosarcoma; LOC102547508; MGC94750; Os-9; osteosarcoma amplified 9; osteosarcoma amplified 9, endoplasmic reticulum lectin; uncharacterized LOC102547508
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,802,517 - 64,829,185 (-)NCBIGRCr8
mRatBN7.2762,915,498 - 62,957,591 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,915,515 - 62,943,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,806,506 - 64,833,054 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,008,904 - 67,035,457 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,809,970 - 66,836,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,378,625 - 70,407,135 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,380,311 - 70,407,177 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,556,327 - 70,584,837 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,046,802 - 67,073,355 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,067,533 - 67,094,085 (-)NCBI
Celera760,060,542 - 60,087,034 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Os9Ratcataract 15 multiple types  ISORGD:16056938554872ClinVar Annotator: match by term: Cataract 15 multiple typesClinVarPMID:28492532
Os9RatCharcot-Marie-Tooth disease axonal type 2U  ISORGD:16056938554872ClinVar Annotator: match by term: CHARCOT-MARIE-TOOTH DISEASE, AXONAL, AUTOSOMAL DOMINANT, TYPE 2UClinVarPMID:28492532
Os9Ratfamilial melanoma  ISORGD:16056938554872ClinVar Annotator: match by term: Familial melanomaClinVarPMID:28492532
Os9RatHereditary Neoplastic Syndromes  ISORGD:16056938554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:25741868
Os9RatINTERSTITIAL LUNG AND LIVER DISEASE  ISORGD:16056938554872ClinVar Annotator: match by term: Interstitial lung and liver diseaseClinVarPMID:28492532
Os9Ratparaplegia  ISORGD:16056938554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532

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Object Symbol
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Original Reference(s)
Os9Rat(1->4)-beta-D-glucan multiple interactionsISORGD:15532966480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of OS9 mRNACTDPMID:36331819
Os9Rat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactionsEXP 64804642,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of OS9 mRNA]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the more ...CTDPMID:19414516
Os9Rat1,2-dimethylhydrazine increases expressionISORGD:155329664804641,2-Dimethylhydrazine results in increased expression of OS9 mRNACTDPMID:22206623
Os9Rat17alpha-ethynylestradiol affects expressionISORGD:15532966480464Ethinyl Estradiol affects the expression of OS9 mRNACTDPMID:17555576
Os9Rat17beta-estradiol decreases expressionISORGD:15532966480464Estradiol results in decreased expression of OS9 mRNACTDPMID:19484750
Os9Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:15532966480464Tetrachlorodibenzodioxin results in decreased expression of OS9 mRNACTDPMID:19465110
Os9Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:15532966480464Tetrachlorodibenzodioxin affects the expression of OS9 mRNACTDPMID:21570461
Os9Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of OS9 mRNACTDPMID:21215274
Os9Rat2,3-dimethoxynaphthalene-1,4-dione decreases expressionISORGD:160569364804642,3-dimethoxy-1,4-naphthoquinone results in decreased expression of OS9 mRNACTDPMID:17547211
Os9Rat2,4-dinitrotoluene affects expressionEXP 64804642,4-dinitrotoluene affects the expression of OS9 mRNACTDPMID:21346803
Os9Rat3',5'-cyclic AMP multiple interactionsEXP 64804642,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of OS9 mRNA]CTDPMID:19414516
Os9Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of OS9 proteinCTDPMID:34915118
Os9Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORGD:16056936480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...CTDPMID:28628672
Os9Rat4,4'-sulfonyldiphenol affects expressionISORGD:15532966480464bisphenol S affects the expression of OS9 mRNACTDPMID:39298647
Os9Ratacrolein multiple interactionsISORGD:16056936480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...CTDPMID:32699268|PMID:32845096
Os9Rataflatoxin B1 decreases expressionISORGD:15532966480464Aflatoxin B1 results in decreased expression of OS9 mRNACTDPMID:19770486
Os9Ratall-trans-retinoic acid multiple interactionsISORGD:16056936480464[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of OS9 mRNACTDPMID:16443354
Os9Ratall-trans-retinoic acid increases expressionISORGD:16056936480464Tretinoin results in increased expression of OS9 mRNACTDPMID:33167477
Os9Ratalpha-pinene multiple interactionsISORGD:16056936480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...CTDPMID:32699268
Os9Ratantimony(0) decreases expressionISORGD:16056936480464Antimony results in decreased expression of OS9 mRNACTDPMID:17547211

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Biological Process
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Original Reference(s)
Os9Ratendoplasmic reticulum unfolded protein response involved_inIEAInterPro:IPR0451491600115GO_REF:0000002InterProGO_REF:0000002
Os9Ratendoplasmic reticulum unfolded protein response involved_inIEAUniRule:UR0016957741600115GO_REF:0000104UniProtGO_REF:0000104
Os9RatERAD pathway involved_inIEAUniRule:UR0016957741600115GO_REF:0000104UniProtGO_REF:0000104
Os9RatERAD pathway involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9RatERAD pathway involved_inIEAInterPro:IPR0451491600115GO_REF:0000002InterProGO_REF:0000002
Os9RatERAD pathway involved_inISSUniProtKB:Q134381600115GO_REF:0000024UniProtGO_REF:0000024
Os9RatERAD pathway involved_inISORGD:16056931624291 PMID:18264092, PMID:18417469, PMID:19346256, PMID:24899641RGDPMID:18264092|PMID:18417469|PMID:19346256|PMID:24899641
Os9Ratnegative regulation of retrograde protein transport, ER to cytosol involved_inISORGD:16056931624291 PMID:25660456RGDPMID:25660456
Os9Ratnegative regulation of retrograde protein transport, ER to cytosol involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratprotein retention in ER lumen involved_inISSUniProtKB:Q134381600115GO_REF:0000024UniProtGO_REF:0000024
Os9Ratprotein retention in ER lumen involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratprotein retention in ER lumen involved_inISORGD:16056931624291 PMID:18417469RGDPMID:18417469
Os9Ratprotein targeting  IDA 1359780 RGD 
Os9Ratprotein ubiquitination involved_inISORGD:16056931624291 PMID:19084021RGDPMID:19084021
Os9Ratprotein ubiquitination involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratresponse to endoplasmic reticulum stress involved_inISORGD:16056931624291 PMID:19084021RGDPMID:19084021
Os9Ratresponse to endoplasmic reticulum stress involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratretrograde protein transport, ER to cytosol involved_inIBAPANTHER:PTN000395729|SGD:S0000024641600115GO_REF:0000033GO_CentralGO_REF:0000033
Os9Ratubiquitin-dependent protein catabolic process involved_inISSUniProtKB:Q134381600115GO_REF:0000024UniProtGO_REF:0000024
Os9Ratubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Original Reference(s)
Os9Ratendoplasmic reticulum located_inISORGD:1605693|UniProtKB:Q13438-1|UniProtKB:Q13438-2|UniProtKB:Q13438-3|UniProtKB:Q13438-4|UniProtKB:Q13438-5|UniProtKB:Q13438-6|UniProtKB:Q13438-7|UniProtKB:Q13438-81624291 RGDGO_REF:0000052
Os9Ratendoplasmic reticulum located_inIEAARBA:ARBA000286721600115GO_REF:0000117UniProtGO_REF:0000117
Os9Ratendoplasmic reticulum located_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Os9Ratendoplasmic reticulum lumen located_inIEAUniProtKB-SubCell:SL-00961600115GO_REF:0000044UniProtGO_REF:0000044
Os9Ratendoplasmic reticulum lumen located_inIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratendoplasmic reticulum lumen is_active_inIBAPANTHER:PTN000395729|RGD:1359574|SGD:S000002464|UniProtKB:Q13438|UniProtKB:Q96DZ11600115GO_REF:0000033GO_CentralGO_REF:0000033
Os9Ratendoplasmic reticulum lumen located_inIEAUniRule:UR0016957741600115GO_REF:0000104UniProtGO_REF:0000104
Os9Ratendoplasmic reticulum lumen located_inIDA 8554273PMID:19084021UniProt 
Os9Ratendoplasmic reticulum lumen located_inISORGD:16056931624291 PMID:18264092, PMID:18417469, PMID:19084021RGDPMID:18264092|PMID:18417469|PMID:19084021
Os9RatHrd1p ubiquitin ligase complex part_ofISORGD:16056931624291 PMID:28827405RGDPMID:28827405
Os9RatHrd1p ubiquitin ligase complex part_ofIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Original Reference(s)
Os9Ratcarbohydrate binding enablesIEAUniProtKB-KW:KW-04301600115GO_REF:0000043UniProtGO_REF:0000043
Os9Ratcarbohydrate binding enablesIEAUniRule:UR0016957741600115GO_REF:0000104UniProtGO_REF:0000104
Os9Ratglycosylation-dependent protein binding enablesISORGD:16056931624291 PMID:24899641RGDPMID:24899641
Os9Ratglycosylation-dependent protein binding enablesIEAUniProtKB:Q13438|ensembl:ENSP000003181651600115GO_REF:0000107EnsemblGO_REF:0000107
Os9Ratprotease binding  IPIRGD:108931359780 RGD 
Os9Ratprotein binding enablesISSUniProtKB:Q134381600115GO_REF:0000024UniProtGO_REF:0000024
Os9Ratprotein binding enablesISORGD:15532961624291UniProtKB:Q9Z140 PMID:10403379RGDPMID:10403379
Os9Ratprotein binding enablesISORGD:1605693|UniProtKB:Q13438-1|UniProtKB:Q13438-21624291UniProtKB:Q8IWF2 PMID:19706418RGDPMID:19706418
Os9Ratprotein binding enablesISORGD:16056931624291UniProtKB:O43889-2|UniProtKB:O75460-1|UniProtKB:P00533|UniProtKB:P11021|UniProtKB:P14625|UniProtKB:Q16665|UniProtKB:Q86TM6|UniProtKB:Q969Y0|UniProtKB:Q96DZ1|UniProtKB:Q96DZ1-1|UniProtKB:Q9GZT9|UniProtKB:Q9H295|UniProtKB:Q9H6Z9|UniProtKB:Q9UBV2 PMID:15721254, PMID:18264092, PMID:18502753, PMID:18711132, PMID:19346256, PMID:20546900, PMID:22119785, PMID:26551274, PMID:26972000, PMID:28827405, PMID:29496332, PMID:33961781, PMID:34591642, more ...RGDPMID:15721254|PMID:18264092|PMID:18502753|PMID:18711132|PMID:19346256|PMID:20546900|PMID:22119785|PMID:26551274|PMID:26972000|PMID:28827405|PMID:29496332|PMID:33961781|PMID:34591642|PMID:35384245
1 to 9 of 9 rows

RGD Manual Annotations


  
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Original Reference(s)
Os9Rathypoxia inducible factor pathway   ISORGD:16056936483358 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
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Original Reference(s)
Os9RatEndoplasmic Reticulum-associated degradation pathway  IEA 6907045 KEGGrno:04141

#
Reference Title
Reference Citation
1. Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins. Alcock F and Swanton E, J Mol Biol. 2009 Jan 30;385(4):1032-42. doi: 10.1016/j.jmb.2008.11.045. Epub 2008 Nov 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta. Litovchick L, etal., J Biol Chem 2002 Sep 13;277(37):34413-23. Epub 2002 Jul 1.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106.
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:18264092   PMID:18417469   PMID:19346256   PMID:21186601   PMID:21454652   PMID:25002582   PMID:25660456  



Os9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,802,517 - 64,829,185 (-)NCBIGRCr8
mRatBN7.2762,915,498 - 62,957,591 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,915,515 - 62,943,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,806,506 - 64,833,054 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,008,904 - 67,035,457 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,809,970 - 66,836,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,378,625 - 70,407,135 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,380,311 - 70,407,177 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,556,327 - 70,584,837 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,046,802 - 67,073,355 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,067,533 - 67,094,085 (-)NCBI
Celera760,060,542 - 60,087,034 (-)NCBICelera
Cytogenetic Map7q22NCBI
OS9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,694,132 - 57,721,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,693,841 - 57,728,342 (+)EnsemblGRCh38hg38GRCh38
GRCh371258,087,915 - 58,115,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,374,153 - 56,401,607 (+)NCBINCBI36Build 36hg18NCBI36
Celera1257,745,335 - 57,772,930 (+)NCBICelera
Cytogenetic Map12q13.3-q14.1NCBI
HuRef1255,124,606 - 55,152,176 (+)NCBIHuRef
CHM1_11258,055,537 - 58,083,142 (+)NCBICHM1_1
T2T-CHM13v2.01257,662,503 - 57,689,908 (+)NCBIT2T-CHM13v2.0
Os9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910126,928,880 - 126,957,029 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10126,931,519 - 126,957,000 (-)EnsemblGRCm39 Ensembl
GRCm3810127,094,259 - 127,121,160 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,095,650 - 127,121,131 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,531,315 - 126,558,216 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,498,599 - 126,524,074 (-)NCBIMGSCv36mm8
Celera10129,486,911 - 129,514,007 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Os9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,407,739 - 5,432,085 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,407,709 - 5,432,646 (+)NCBIChiLan1.0ChiLan1.0
OS9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,619,441 - 36,646,957 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,616,212 - 36,643,728 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,205,239 - 31,232,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,465,836 - 31,493,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,463,716 - 31,493,076 (-)Ensemblpanpan1.1panPan2
OS9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,757,070 - 1,787,822 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,757,103 - 1,787,203 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,820,251 - 1,851,006 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,766,439 - 1,797,192 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,766,407 - 1,797,188 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,744,195 - 1,774,942 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,986,092 - 2,017,042 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0102,111,143 - 2,141,905 (+)NCBIUU_Cfam_GSD_1.0
Os9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,010,035 - 57,037,803 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,832,015 - 1,859,576 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,832,434 - 1,860,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OS9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,957,875 - 23,004,458 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,957,903 - 23,004,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OS9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,606,916 - 53,635,152 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,607,008 - 53,635,793 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,327,156 - 192,355,401 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Os9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,222,259 - 10,252,039 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,221,633 - 10,252,008 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Os9
142 total Variants

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:56
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000049895
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat

1 to 10 of 36 rows
RH127553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2762,917,352 - 62,917,560 (+)MAPPERmRatBN7.2
Rnor_6.0770,380,480 - 70,380,687NCBIRnor6.0
Rnor_5.0770,558,182 - 70,558,389UniSTSRnor5.0
RGSC_v3.4767,046,967 - 67,047,174UniSTSRGSC3.4
Celera760,060,707 - 60,060,914UniSTS
Cytogenetic Map7q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000049895   ⟹   ENSRNOP00000044914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl762,917,190 - 62,943,745 (-)Ensembl
Rnor_6.0 Ensembl770,380,311 - 70,407,177 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114368   ⟹   ENSRNOP00000084934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl762,917,190 - 62,943,745 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117544   ⟹   ENSRNOP00000093535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl762,915,515 - 62,943,731 (-)Ensembl
RefSeq Acc Id: NM_001007265   ⟹   NP_001007266
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,802,517 - 64,829,070 (-)NCBI
mRatBN7.2762,917,188 - 62,943,745 (-)NCBI
Rnor_6.0770,380,315 - 70,407,114 (-)NCBI
Rnor_5.0770,556,327 - 70,584,837 (-)NCBI
RGSC_v3.4767,046,802 - 67,073,355 (-)RGD
Celera760,060,542 - 60,087,034 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241461   ⟹   XP_006241523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,802,517 - 64,829,185 (-)NCBI
mRatBN7.2762,915,498 - 62,943,766 (-)NCBI
Rnor_6.0770,378,625 - 70,407,135 (-)NCBI
Rnor_5.0770,556,327 - 70,584,837 (-)NCBI
Sequence:
Protein RefSeqs NP_001007266 (Get FASTA)   NCBI Sequence Viewer  
  XP_006241523 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85907 (Get FASTA)   NCBI Sequence Viewer  
  EDM16497 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044914
  ENSRNOP00000044914.2
  ENSRNOP00000093535
GenBank Protein Q5RKH6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007266   ⟸   NM_001007265
- Peptide Label: precursor
- UniProtKB: Q5RKH6 (UniProtKB/Swiss-Prot),   A0A8I5ZYZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241523   ⟸   XM_006241461
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GKC0 (UniProtKB/TrEMBL),   A0A8I5ZYZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000044914   ⟸   ENSRNOT00000049895
Ensembl Acc Id: ENSRNOP00000093535   ⟸   ENSRNOT00000117544
Ensembl Acc Id: ENSRNOP00000084934   ⟸   ENSRNOT00000114368
MRH

Name Modeler Protein Id AA Range Protein Structure
AF-Q5RKH6-F1-model_v2 AlphaFold Q5RKH6 1-666 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695249
Promoter ID:EPDNEW_R5774
Type:multiple initiation site
Name:Os9_1
Description:OS9, endoplasmic reticulum lectin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0770,407,101 - 70,407,161EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-33773 BioCyc
Ensembl Genes ENSRNOG00000025570 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000049895 ENTREZGENE
  ENSRNOT00000049895.4 UniProtKB/Swiss-Prot
  ENSRNOT00000117544 ENTREZGENE
Gene3D-CATH 2.70.130.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7096059 IMAGE-MGC_LOAD
InterPro Man6P_isomerase_rcpt-bd_dom_sf UniProtKB/Swiss-Prot
  MRH_dom UniProtKB/Swiss-Prot
  OS-9-like UniProtKB/Swiss-Prot
  OS9-like UniProtKB/Swiss-Prot
KEGG Report rno:362891 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94750 IMAGE-MGC_LOAD
NCBI Gene 362891 ENTREZGENE
PANTHER PROTEIN OS-9 UniProtKB/Swiss-Prot
  PTHR15414 UniProtKB/Swiss-Prot
Pfam PRKCSH UniProtKB/Swiss-Prot
PhenoGen Os9 PhenoGen
PROSITE MRH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000025570 RatGTEx
Superfamily-SCOP SSF50911 UniProtKB/Swiss-Prot
UniProt A0A8I5ZYZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GKC0 ENTREZGENE, UniProtKB/TrEMBL
  OS9_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Os9  OS9, endoplasmic reticulum lectin  LOC102547508  uncharacterized LOC102547508  Data merged from RGD:7633170 737654 PROVISIONAL
2016-05-20 Os9  OS9, endoplasmic reticulum lectin  Os9  osteosarcoma amplified 9, endoplasmic reticulum lectin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-10 Os9  osteosarcoma amplified 9, endoplasmic reticulum lectin  Os9  osteosarcoma amplified 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102547508  uncharacterized LOC102547508      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-04-23 Os9  osteosarcoma amplified 9  Os9  amplified in osteosarcoma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Os9  amplified in osteosarcoma  Os-9  amplified in osteosarcoma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Os-9  amplified in osteosarcoma      Symbol and Name status set to provisional 70820 PROVISIONAL