1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of YWHAZ mRNA CTD PMID:25380136 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of YWHAZ mRNA CTD PMID:15953391 , PMID:17108234 17beta-estradiol increases expression ISO RGD:736756 6480464 Estradiol results in increased expression of YWHAZ mRNA CTD PMID:19167446 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:11498 6480464 [3 more ... CTD PMID:23457121 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:11498 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:11498 6480464 Tetrachlorodibenzodioxin affects the expression of YWHAZ mRNA CTD PMID:21570461 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19954255 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO RGD:11498 6480464 2 more ... CTD PMID:18550172 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of YWHAZ mRNA CTD PMID:21346803 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:11498 6480464 [3 more ... CTD PMID:23457121 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of YWHAZ mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane increases expression ISO RGD:11498 6480464 4, 4'-diaminodiphenylmethane results in increased expression of YWHAZ mRNA CTD PMID:18648102 4-hydroperoxycyclophosphamide decreases expression ISO RGD:11498 6480464 perfosfamide results in decreased expression of YWHAZ mRNA CTD PMID:19429390 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:12376462 acetylsalicylic acid multiple interactions ISO RGD:736756 6480464 Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of YWHAZ protein] CTD PMID:17303692 afimoxifene increases expression ISO RGD:736756 6480464 afimoxifene results in increased expression of YWHAZ mRNA CTD PMID:16849584 aflatoxin B1 increases expression ISO RGD:736756 6480464 Aflatoxin B1 results in increased expression of YWHAZ mRNA CTD PMID:27153756 aflatoxin B1 decreases methylation ISO RGD:736756 6480464 Aflatoxin B1 results in decreased methylation of YWHAZ gene CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:736756 6480464 Tretinoin results in decreased expression of YWHAZ mRNA CTD PMID:15498508 arachidonic acid increases expression ISO RGD:736756 6480464 Arachidonic Acid results in increased expression of YWHAZ mRNA CTD PMID:16704987 Aroclor 1254 decreases expression ISO RGD:11498 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of YWHAZ mRNA CTD PMID:23650126 arsenous acid decreases response to substance ISO RGD:736756 6480464 YWHAZ protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:19364129 arsenous acid decreases expression ISO RGD:736756 6480464 Arsenic Trioxide results in decreased expression of YWHAZ protein CTD PMID:19364129 arsenous acid increases expression ISO RGD:736756 6480464 Arsenic Trioxide results in increased expression of YWHAZ mRNA CTD PMID:11940349 benzo[a]pyrene increases expression ISO RGD:11498 6480464 Benzo(a)pyrene results in increased expression of YWHAZ mRNA CTD PMID:20127859 , PMID:22228805 benzo[a]pyrene multiple interactions ISO RGD:11498 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of YWHAZ mRNA CTD PMID:27858113 benzo[b]fluoranthene multiple interactions ISO RGD:11498 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of YWHAZ mRNA CTD PMID:27858113 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of YWHAZ mRNA CTD PMID:25181051 bortezomib increases expression ISO RGD:736756 6480464 Bortezomib results in increased expression of YWHAZ mRNA CTD PMID:20977926 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of YWHAZ mRNA CTD PMID:12628495 cadmium atom increases expression ISO RGD:736756 6480464 Cadmium results in increased expression of YWHAZ mRNA CTD PMID:23369406 cadmium dichloride increases expression ISO RGD:736756 6480464 Cadmium Chloride results in increased expression of YWHAZ protein CTD PMID:24527689 calcium atom affects expression EXP 6480464 Calcium affects the expression of YWHAZ mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of YWHAZ mRNA CTD PMID:15913539 carbon nanotube increases expression ISO RGD:11498 6480464 Nanotubes, Carbon results in increased expression of YWHAZ mRNA CTD PMID:25554681 chloropicrin decreases expression ISO RGD:736756 6480464 chloropicrin results in decreased expression of YWHAZ mRNA CTD PMID:26352163 chloroprene decreases expression ISO RGD:11498 6480464 Chloroprene results in decreased expression of YWHAZ mRNA CTD PMID:23125180 chrysene multiple interactions ISO RGD:11498 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of YWHAZ mRNA CTD PMID:27858113 cisplatin multiple interactions ISO RGD:736756 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of YWHAZ mRNA CTD PMID:27392435 cobalt dichloride decreases expression ISO RGD:736756 6480464 cobaltous chloride results in decreased expression of YWHAZ mRNA CTD PMID:19376846 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of YWHAZ protein CTD PMID:24386269 copper atom decreases expression ISO RGD:736756 6480464 Copper results in decreased expression of YWHAZ protein CTD PMID:22692975 copper(0) decreases expression ISO RGD:736756 6480464 Copper results in decreased expression of YWHAZ protein CTD PMID:22692975 copper(II) sulfate increases expression ISO RGD:736756 6480464 Copper Sulfate results in increased expression of YWHAZ mRNA CTD PMID:19549813 CU-O LINKAGE decreases expression ISO RGD:11498 6480464 cupric oxide analog results in decreased expression of YWHAZ protein CTD PMID:23882024 decabromodiphenyl ether decreases expression ISO RGD:11498 6480464 decabromobiphenyl ether results in decreased expression of YWHAZ mRNA CTD PMID:29699156 diarsenic trioxide decreases expression ISO RGD:736756 6480464 Arsenic Trioxide results in decreased expression of YWHAZ protein CTD PMID:19364129 diarsenic trioxide decreases response to substance ISO RGD:736756 6480464 YWHAZ protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:19364129 diarsenic trioxide increases expression ISO RGD:736756 6480464 Arsenic Trioxide results in increased expression of YWHAZ mRNA CTD PMID:11940349 dichlorine increases expression EXP 6480464 Chlorine results in increased expression of YWHAZ mRNA CTD PMID:18636392 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA CTD PMID:18636392 dioxygen decreases expression ISO RGD:11498 6480464 Oxygen deficiency results in decreased expression of YWHAZ protein CTD PMID:25937538 doxorubicin multiple interactions ISO RGD:11498 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein] CTD PMID:21251210 doxorubicin increases oxidation EXP 6480464 Doxorubicin results in increased oxidation of YWHAZ protein CTD PMID:28818578 doxorubicin decreases expression ISO RGD:11498 6480464 Doxorubicin results in decreased expression of YWHAZ protein CTD PMID:21251210 elemental selenium multiple interactions ISO RGD:736756 6480464 [Selenium co-treated with Vitamin E] results in increased expression of YWHAZ mRNA CTD PMID:19244175 enzyme inhibitor multiple interactions ISO RGD:736756 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of YWHAZ protein CTD PMID:23301498 ethanol multiple interactions ISO RGD:11498 6480464 Ethanol affects the expression of and affects the splicing of YWHAZ mRNA CTD PMID:30319688 ethanol increases expression ISO RGD:11498 6480464 Ethanol results in increased expression of YWHAZ mRNA CTD PMID:30319688 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of YWHAZ mRNA CTD PMID:18035473 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of YWHAZ mRNA, Fluoxetine results in increased expression of YWHAZ protein CTD PMID:15631896 flutamide increases expression EXP 6480464 Flutamide results in increased expression of YWHAZ mRNA CTD PMID:24136188 fumonisin B1 increases expression ISO RGD:11498 6480464 fumonisin B1 results in increased expression of YWHAZ mRNA CTD PMID:16221962 furan increases expression EXP 6480464 furan results in increased expression of YWHAZ mRNA CTD PMID:15120968 hypochlorous acid increases expression ISO RGD:11498 6480464 Hypochlorous Acid results in increased expression of YWHAZ mRNA CTD PMID:19376150 manganese(II) chloride affects methylation ISO RGD:736756 6480464 manganese chloride affects the methylation of YWHAZ gene CTD PMID:27913844 manganese(II) chloride decreases expression ISO RGD:736756 6480464 manganese chloride results in decreased expression of YWHAZ mRNA CTD PMID:27913844 mercury atom decreases expression ISO RGD:736756 6480464 Mercury results in decreased expression of YWHAZ mRNA CTD PMID:16823088 mercury(0) decreases expression ISO RGD:736756 6480464 Mercury results in decreased expression of YWHAZ mRNA CTD PMID:16823088 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of YWHAZ mRNA CTD PMID:16393664 microcystin-LR increases expression ISO RGD:11498 6480464 cyanoginosin LR results in increased expression of YWHAZ mRNA CTD PMID:17654400 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:736756 6480464 N more ... CTD PMID:18778698 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:736756 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 N-nitrosodiethylamine multiple interactions ISO RGD:11498 6480464 [3 more ... CTD PMID:23457121 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of YWHAZ mRNA CTD PMID:25380136 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of YWHAZ mRNA CTD PMID:24136188 nitroglycerin decreases expression EXP 6480464 Nitroglycerin results in decreased expression of YWHAZ mRNA CTD PMID:12102619 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of YWHAZ protein CTD PMID:31369848 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA CTD PMID:18636392 p-menthan-3-ol decreases expression ISO RGD:736756 6480464 Menthol results in decreased expression of YWHAZ protein CTD PMID:26760959 paclitaxel increases expression EXP 6480464 Paclitaxel analog results in increased expression of YWHAZ mRNA, Paclitaxel results in increased expression of YWHAZ mRNA CTD PMID:15585946 pentachlorophenol increases expression ISO RGD:11498 6480464 Pentachlorophenol results in increased expression of YWHAZ mRNA CTD PMID:23892564 phenethyl isothiocyanate affects binding ISO RGD:736756 6480464 YWHAZ protein binds to phenethyl isothiocyanate CTD PMID:21838287 phenobarbital affects expression ISO RGD:11498 6480464 Phenobarbital affects the expression of YWHAZ mRNA CTD PMID:23091169 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of YWHAZ mRNA CTD PMID:12376462 prostaglandin F2alpha increases expression EXP 6480464 Dinoprost results in increased expression of YWHAZ mRNA CTD PMID:11517196 resveratrol decreases expression ISO RGD:736756 6480464 resveratrol results in decreased expression of YWHAZ mRNA CTD PMID:12569576 resveratrol decreases expression ISO RGD:11498 6480464 resveratrol results in decreased expression of YWHAZ protein CTD PMID:25505154 resveratrol affects expression EXP 6480464 resveratrol affects the expression of YWHAZ mRNA CTD PMID:15748624 retinyl acetate increases expression ISO RGD:11498 6480464 retinol acetate results in increased expression of YWHAZ mRNA CTD PMID:16772331 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of YWHAZ mRNA CTD PMID:24002177 selenium atom multiple interactions ISO RGD:736756 6480464 [Selenium co-treated with Vitamin E] results in increased expression of YWHAZ mRNA CTD PMID:19244175 silicon dioxide affects secretion ISO RGD:736756 6480464 Silicon Dioxide analog affects the secretion of YWHAZ protein CTD PMID:25895662 sodium arsenate increases expression ISO RGD:11498 6480464 sodium arsenate results in increased expression of YWHAZ mRNA CTD PMID:21795629 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of YWHAZ protein CTD PMID:29459688 sodium fluoride increases expression ISO RGD:11498 6480464 Sodium Fluoride results in increased expression of YWHAZ mRNA, Sodium Fluoride results in increased expression of YWHAZ protein CTD PMID:27548804 , PMID:27862939 sodium nitrate multiple interactions ISO RGD:11498 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of YWHAZ protein] CTD PMID:21251210 sunitinib increases expression ISO RGD:736756 6480464 Sunitinib results in increased expression of YWHAZ mRNA CTD PMID:31533062 tamibarotene affects expression ISO RGD:736756 6480464 tamibarotene affects the expression of YWHAZ mRNA CTD PMID:15498508 tetraphene multiple interactions ISO RGD:11498 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of YWHAZ mRNA CTD PMID:27858113 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of YWHAZ mRNA CTD PMID:23411599 titanium dioxide increases phosphorylation ISO RGD:736756 6480464 titanium dioxide results in increased phosphorylation of YWHAZ protein CTD PMID:21439344 toluene affects expression EXP 6480464 Toluene affects the expression of YWHAZ mRNA CTD PMID:21827849 triacsin C increases expression ISO RGD:736756 6480464 triacsin C results in increased expression of YWHAZ mRNA CTD PMID:16704987 valproic acid affects expression ISO RGD:11498 6480464 Valproic Acid affects the expression of YWHAZ mRNA CTD PMID:17963808 valproic acid decreases expression ISO RGD:736756 6480464 Valproic Acid results in decreased expression of YWHAZ mRNA CTD PMID:29154799 vitamin E multiple interactions ISO RGD:736756 6480464 [Selenium co-treated with Vitamin E] results in increased expression of YWHAZ mRNA CTD PMID:19244175 zoledronic acid decreases expression ISO RGD:736756 6480464 zoledronic acid results in decreased expression of YWHAZ protein CTD PMID:28871336
Biological Process angiogenesis IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 ERK1 and ERK2 cascade IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 establishment of Golgi localization ISO RGD:736756 1624291 (PMID:20332113) RGD PMID:20332113 establishment of Golgi localization IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 Golgi reassembly ISO RGD:736756 1624291 (PMID:20332113) RGD PMID:20332113 Golgi reassembly IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 histamine secretion by mast cell IMP 1625716 RGD lung development IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein phosphorylation ISO RGD:736756 1624291 (PMID:31024343) RGD PMID:31024343 protein phosphorylation ISS UniProtKB:P63104 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein targeting ISO RGD:11498 1624291 (MGI:MGI:2446408, PMID:12446771) RGD MGI:MGI:2446408 , PMID:12446771 protein targeting IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein targeting to mitochondrion IDA 727986 RGD regulation of cell death ISO RGD:11498 1624291 MGI:MGI:1346876 (MGI:MGI:4353570 , PMID:19451227) RGD MGI:MGI:4353570 , PMID:19451227 regulation of cell death IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of ERK1 and ERK2 cascade ISO RGD:736756 1624291 (PMID:31024343) RGD PMID:31024343 regulation of ERK1 and ERK2 cascade IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of ERK1 and ERK2 cascade ISS UniProtKB:P63104 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of synapse maturation IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of synapse maturation ISO RGD:736756 1624291 (PMID:16959763) RGD PMID:16959763 respiratory system process IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to drug IDA 1625715 RGD signal transduction ISO RGD:736756 1624291 (PMID:31024343) RGD PMID:31024343 signal transduction ISS UniProtKB:P63104 1600115 GO_REF:0000024 UniProt GO_REF:0000024 synaptic target recognition IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 synaptic target recognition ISO RGD:11498 1624291 (MGI:MGI:5613710, PMID:22124272) RGD MGI:MGI:5613710 , PMID:22124272 tube formation IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 Cellular Component cell leading edge IDA 1299103 RGD glutamatergic synapse IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutamatergic synapse ISO RGD:736756 1624291 (PMID:16959763) RGD PMID:16959763 hippocampal mossy fiber to CA3 synapse IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 hippocampal mossy fiber to CA3 synapse ISO RGD:11498 1624291 (MGI:MGI:5613710, PMID:22124272) RGD MGI:MGI:5613710 , PMID:22124272 mast cell granule IEA GO:0002553 1600115 GO_REF:0000108 GOC GO_REF:0000108 melanosome IEA UniProtKB-SubCell:SL-0161 1600115 GO_REF:0000044 UniProt GO_REF:0000044 mitochondrion IDA 1625714 RGD nucleus ISO RGD:11498 1624291 (MGI:MGI:3522382, PMID:15615787) RGD MGI:MGI:3522382 , PMID:15615787 nucleus IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 perinuclear region of cytoplasm IDA 1299103 RGD postsynaptic density IDA 1625722 RGD protein-containing complex IDA 1625718 RGD Molecular Function identical protein binding ISO RGD:736756 1624291 UniProtKB:P63104 (PMID:16376338), (PMID:20618440) RGD PMID:16376338 , PMID:20618440 identical protein binding IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 ion channel binding ISO RGD:736756 1624291 UniProtKB:Q16720 (PMID:18029012) RGD PMID:18029012 ion channel binding IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding IPI RGD:708400 1299103 RGD protein binding ISO RGD:11498 1624291 PR:O35099 more ... RGD MGI:MGI:2388865 more ... protein binding ISO RGD:736756 1624291 UniProtKB:O00257-3 more ... RGD PMID:10026197 more ... protein binding IPI UniProtKB:O54918 8554586 PMID:21478148 UniProt protein binding IPI RGD:61857 1625718 RGD protein domain specific binding ISO RGD:11498 1624291 (MGI:MGI:2388865, PMID:12176995) RGD MGI:MGI:2388865 , PMID:12176995 protein domain specific binding IEA UniProtKB:P63101 , ensembl:ENSMUSP000000228941600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein domain specific binding ISS UniProtKB:P63101 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein kinase binding ISO RGD:736756 1624291 UniProtKB:P31749 (PMID:10102273) RGD PMID:10102273 protein kinase binding IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein-containing complex binding IPI RGD:61857 , RGD:71096 1625718 RGD transcription factor binding ISO RGD:736756 1624291 UniProtKB:P98177 (PMID:16114898) RGD PMID:16114898 transcription factor binding IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 ubiquitin protein ligase binding IEA UniProtKB:P63104 , ensembl:ENSP000003792871600115 GO_REF:0000107 Ensembl GO_REF:0000107 ubiquitin protein ligase binding ISO RGD:736756 1624291 UniProtKB:O60260 (PMID:19725078) RGD PMID:19725078
Gene-Chemical Interaction Annotations
