YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) - Rat Genome Database

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Gene: YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) Homo sapiens
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Symbol: YWHAZ
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
RGD ID: 736756
HGNC Page HGNC:12855
Description: Enables several functions, including enzyme binding activity; protein sequestering activity; and transmembrane transporter binding activity. Involved in several processes, including Golgi reassembly; establishment of Golgi localization; and regulation of ERK1 and ERK2 cascade. Located in several cellular components, including blood microparticle; extracellular exosome; and focal adhesion. Is active in glutamatergic synapse. Biomarker of hepatocellular carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 14-3-3 delta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 zeta; 14-3-3-zeta; epididymis luminal protein 4; epididymis secretory protein Li 3; epididymis secretory protein Li 93; HEL-S-3; HEL-S-93; HEL4; KCIP-1; MGC111427; MGC126532; MGC138156; phospholipase A2; POPCHAS; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; YWHAD
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100422669   YWHAZP1   YWHAZP10   YWHAZP2   YWHAZP3   YWHAZP4   YWHAZP5   YWHAZP6   YWHAZP7   YWHAZP8   YWHAZP9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388100,916,523 - 100,953,382 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8100,916,523 - 100,953,388 (-)EnsemblGRCh38hg38GRCh38
GRCh378101,928,751 - 101,965,610 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,000,090 - 102,034,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 348102,000,089 - 102,033,447NCBI
Celera898,115,836 - 98,150,667 (-)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef897,128,746 - 97,163,575 (-)NCBIHuRef
CHM1_18101,971,677 - 102,006,519 (-)NCBICHM1_1
T2T-CHM13v2.08102,042,222 - 102,079,082 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroperoxycyclophosphamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetylsalicylic acid  (EXP)
acrolein  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
alpha-pinene  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
arachidonic acid  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
bortezomib  (EXP)
bromobenzene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chloropicrin  (EXP)
chloroprene  (ISO)
chrysene  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
CU-O LINKAGE  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP)
dichlorine  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
elemental selenium  (EXP)
enzyme inhibitor  (EXP)
ethanol  (ISO)
fipronil  (ISO)
flavonoids  (ISO)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
folpet  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
hypochlorous acid  (ISO)
ivermectin  (EXP)
manganese(II) chloride  (EXP)
mercury atom  (EXP)
mercury(0)  (EXP)
methapyrilene  (ISO)
microcystin-LR  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nitroglycerin  (ISO)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
PhIP  (ISO)
prostaglandin F2alpha  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
rotenone  (ISO)
selenium atom  (EXP)
silicon dioxide  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sodium nitrate  (ISO)
sunitinib  (EXP)
tamibarotene  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
triacsin C  (EXP)
trichloroethene  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vitamin E  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival. Chen M, etal., Oncotarget. 2016 Dec 6;7(49):80751-80764. doi: 10.18632/oncotarget.13037.
2. Changes in intracellular protein expression in cortex, thalamus and hippocampus in a genetic rat model of absence epilepsy. Danis O, etal., Brain Res Bull. 2011 Apr 5;84(6):381-8. doi: 10.1016/j.brainresbull.2011.02.002. Epub 2011 Feb 15.
3. 14-3-3 proteins within the hypothalamic-neurohypophyseal system of the osmotically stressed rat: transcriptomic and proteomic studies. Gouraud SS, etal., J Neuroendocrinol. 2007 Nov;19(11):913-22.
4. Proteomic response to acupuncture treatment in spontaneously hypertensive rats. Lai X, etal., PLoS One. 2012;7(9):e44216. doi: 10.1371/journal.pone.0044216. Epub 2012 Sep 12.
5. Readout of epigenetic modifications. Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Isoform- and subcellular fraction-specific differences in hippocampal 14-3-3 levels following experimentally evoked seizures and in human temporal lobe epilepsy. Schindler CK, etal., J Neurochem. 2006 Oct;99(2):561-9. Epub 2006 Sep 18.
Additional References at PubMed
PMID:1577711   PMID:7536343   PMID:7547034   PMID:7559537   PMID:7603574   PMID:7628630   PMID:7890696   PMID:7935795   PMID:7939632   PMID:7939633   PMID:8024705   PMID:8034572  
PMID:8037685   PMID:8085158   PMID:8101440   PMID:8278375   PMID:8601312   PMID:8617504   PMID:8619474   PMID:8631758   PMID:8668348   PMID:8702721   PMID:9092538   PMID:9110174  
PMID:9115393   PMID:9144171   PMID:9153224   PMID:9197417   PMID:9261098   PMID:9299557   PMID:9312143   PMID:9360956   PMID:9367879   PMID:9398266   PMID:9425086   PMID:9428519  
PMID:9452471   PMID:9454760   PMID:9512661   PMID:9524113   PMID:9543386   PMID:9581554   PMID:9620776   PMID:9632690   PMID:9705322   PMID:9858547   PMID:10026197   PMID:10102273  
PMID:10224112   PMID:10358015   PMID:10407019   PMID:10411906   PMID:10441394   PMID:10455159   PMID:10477722   PMID:10488331   PMID:10559254   PMID:10611249   PMID:10620507   PMID:10627461  
PMID:10642536   PMID:10644344   PMID:10681541   PMID:10713667   PMID:10785390   PMID:10835362   PMID:10840038   PMID:10864927   PMID:10887121   PMID:10887173   PMID:11124266   PMID:11178869  
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PMID:11985497   PMID:12176984   PMID:12176995   PMID:12215538   PMID:12323073   PMID:12361576   PMID:12364343   PMID:12383250   PMID:12433946   PMID:12438239   PMID:12468542   PMID:12477932  
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PMID:19056867   PMID:19062179   PMID:19135240   PMID:19138662   PMID:19172738   PMID:19173300   PMID:19184136   PMID:19190083   PMID:19198587   PMID:19199708   PMID:19218246   PMID:19338310  
PMID:19357195   PMID:19371722   PMID:19401330   PMID:19427857   PMID:19525224   PMID:19531499   PMID:19647741   PMID:19662078   PMID:19667065   PMID:19725029   PMID:19725078   PMID:19732720  
PMID:19738201   PMID:19766566   PMID:19860830   PMID:19875727   PMID:19933840   PMID:19940019   PMID:20000738   PMID:20012529   PMID:20037628   PMID:20052757   PMID:20129940   PMID:20224040  
PMID:20308060   PMID:20332113   PMID:20379614   PMID:20381070   PMID:20384366   PMID:20388496   PMID:20451386   PMID:20458337   PMID:20471030   PMID:20478393   PMID:20603015   PMID:20618440  
PMID:20642453   PMID:20679480   PMID:20843328   PMID:20885446   PMID:20936779   PMID:21028892   PMID:21076048   PMID:21081103   PMID:21081150   PMID:21081666   PMID:21118500   PMID:21145461  
PMID:21145499   PMID:21182262   PMID:21209461   PMID:21242845   PMID:21282530   PMID:21302295   PMID:21319273   PMID:21334806   PMID:21423176   PMID:21533173   PMID:21554249   PMID:21621563  
PMID:21630459   PMID:21706016   PMID:21707964   PMID:21743495   PMID:21800051   PMID:21832049   PMID:21873635   PMID:21900206   PMID:21903422   PMID:21965683   PMID:21978388   PMID:21988832  
PMID:22001647   PMID:22010828   PMID:22069327   PMID:22072711   PMID:22124272   PMID:22190034   PMID:22222486   PMID:22268729   PMID:22279540   PMID:22450169   PMID:22450747   PMID:22516433  
PMID:22575644   PMID:22580824   PMID:22588126   PMID:22623428   PMID:22653443   PMID:22658674   PMID:22754302   PMID:22794279   PMID:22808202   PMID:22863883   PMID:22865885   PMID:22904106  
PMID:22912335   PMID:22922483   PMID:22939629   PMID:22948661   PMID:22952844   PMID:22989890   PMID:22990118   PMID:23075850   PMID:23125841   PMID:23175360   PMID:23269842   PMID:23271328  
PMID:23316005   PMID:23318431   PMID:23364796   PMID:23383273   PMID:23397142   PMID:23402259   PMID:23414517   PMID:23422756   PMID:23428871   PMID:23438482   PMID:23444366   PMID:23455924  
PMID:23533145   PMID:23572552   PMID:23580065   PMID:23603156   PMID:23622247   PMID:23667531   PMID:23752268   PMID:23754751   PMID:23824909   PMID:23956138   PMID:23962087   PMID:23977325  
PMID:23999528   PMID:24043626   PMID:24114522   PMID:24129571   PMID:24189400   PMID:24255178   PMID:24269678   PMID:24282540   PMID:24351927   PMID:24367683   PMID:24510904   PMID:24550385  
PMID:24603438   PMID:24658140   PMID:24687993   PMID:24708873   PMID:24711643   PMID:24804299   PMID:24812321   PMID:24947832   PMID:24956593   PMID:24999758   PMID:25036637   PMID:25138042  
PMID:25147182   PMID:25154416   PMID:25156059   PMID:25189701   PMID:25192599   PMID:25226601   PMID:25266655   PMID:25277244   PMID:25324306   PMID:25330109   PMID:25402006   PMID:25412315  
PMID:25418103   PMID:25468996   PMID:25556369   PMID:25670079   PMID:25681748   PMID:25737280   PMID:25756610   PMID:25770209   PMID:25798074   PMID:25852190   PMID:25861752   PMID:25900982  
PMID:25921289   PMID:25940091   PMID:25959826   PMID:25963833   PMID:25971962   PMID:26186194   PMID:26205494   PMID:26217791   PMID:26295714   PMID:26318153   PMID:26344197   PMID:26375402  
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PMID:26906158   PMID:26910835   PMID:26972000   PMID:27030512   PMID:27030597   PMID:27034005   PMID:27058640   PMID:27080223   PMID:27142060   PMID:27150057   PMID:27248496   PMID:27261462  
PMID:27291054   PMID:27334574   PMID:27401462   PMID:27432908   PMID:27453043   PMID:27462432   PMID:27548710   PMID:27554601   PMID:27591049   PMID:27637333   PMID:27684187   PMID:27751915  
PMID:27764807   PMID:27880917   PMID:27984090   PMID:28202711   PMID:28205554   PMID:28302793   PMID:28330616   PMID:28368277   PMID:28443643   PMID:28514442   PMID:28515276   PMID:28522826  
PMID:28575131   PMID:28581483   PMID:28643021   PMID:28675297   PMID:28842482   PMID:28864297   PMID:28943433   PMID:28944820   PMID:28981108   PMID:29069755   PMID:29089450   PMID:29100370  
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PMID:30585270   PMID:30656845   PMID:30737378   PMID:30745168   PMID:30833792   PMID:30890647   PMID:30945298   PMID:31024343   PMID:31040226   PMID:31046837   PMID:31048545   PMID:31059266  
PMID:31068674   PMID:31091453   PMID:31180492   PMID:31199037   PMID:31222857   PMID:31240211   PMID:31273033   PMID:31298411   PMID:31300519   PMID:31396202   PMID:31405213   PMID:31409639  
PMID:31413325   PMID:31436131   PMID:31519766   PMID:31536960   PMID:31586073   PMID:31610265   PMID:31620119   PMID:31640760   PMID:31665637   PMID:31693753   PMID:31709727   PMID:31732153  
PMID:31856438   PMID:31871319   PMID:31980649   PMID:31988522   PMID:31995728   PMID:32108043   PMID:32120844   PMID:32129710   PMID:32152128   PMID:32236580   PMID:32296183   PMID:32457219  
PMID:32509391   PMID:32552912   PMID:32597834   PMID:32665550   PMID:32685476   PMID:32685532   PMID:32687490   PMID:32707033   PMID:32807901   PMID:32814053   PMID:32814769   PMID:32850835  
PMID:32877691   PMID:32905556   PMID:32913128   PMID:32929329   PMID:32989225   PMID:33022573   PMID:33159816   PMID:33194618   PMID:33201331   PMID:33222276   PMID:33239621   PMID:33254518  
PMID:33306668   PMID:33386589   PMID:33416155   PMID:33545068   PMID:33644029   PMID:33658012   PMID:33729478   PMID:33731348   PMID:33761321   PMID:33863777   PMID:33875576   PMID:33916271  
PMID:33961781   PMID:33999101   PMID:34031189   PMID:34079125   PMID:34185411   PMID:34294877   PMID:34454032   PMID:34560418   PMID:34654719   PMID:34674391   PMID:34709727   PMID:34728620  
PMID:34757658   PMID:34795231   PMID:35006623   PMID:35013218   PMID:35078985   PMID:35122331   PMID:35134439   PMID:35168653   PMID:35213938   PMID:35256949   PMID:35271311   PMID:35343654  
PMID:35356984   PMID:35387560   PMID:35446349   PMID:35457075   PMID:35509820   PMID:35545034   PMID:35546148   PMID:35562734   PMID:35662396   PMID:35676659   PMID:35681168   PMID:35831314  
PMID:35831895   PMID:35851744   PMID:35876652   PMID:35944360   PMID:35993436   PMID:36001342   PMID:36042349   PMID:36042481   PMID:36055981   PMID:36114006   PMID:36199071   PMID:36199425  
PMID:36213322   PMID:36215168   PMID:36282215  


Genomics

Comparative Map Data
YWHAZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388100,916,523 - 100,953,382 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8100,916,523 - 100,953,388 (-)EnsemblGRCh38hg38GRCh38
GRCh378101,928,751 - 101,965,610 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,000,090 - 102,034,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 348102,000,089 - 102,033,447NCBI
Celera898,115,836 - 98,150,667 (-)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef897,128,746 - 97,163,575 (-)NCBIHuRef
CHM1_18101,971,677 - 102,006,519 (-)NCBICHM1_1
T2T-CHM13v2.08102,042,222 - 102,079,082 (-)NCBIT2T-CHM13v2.0
Ywhaz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391536,770,505 - 36,803,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1536,771,014 - 36,797,173 (-)EnsemblGRCm39 Ensembl
GRCm381536,770,261 - 36,802,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1536,770,770 - 36,796,929 (-)EnsemblGRCm38mm10GRCm38
MGSCv371536,700,016 - 36,724,293 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361536,715,359 - 36,738,833 (-)NCBIMGSCv36mm8
Celera1537,392,750 - 37,416,932 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
Ywhaz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2767,941,353 - 67,963,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl767,940,017 - 67,963,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx769,829,731 - 69,852,029 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0772,032,344 - 72,054,642 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0771,900,221 - 71,922,519 (-)NCBIRnor_WKY
Rnor_6.0775,573,553 - 75,598,295 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl775,574,967 - 75,597,276 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0775,719,688 - 75,744,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,283,825 - 72,306,126 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1772,304,554 - 72,327,161 (-)NCBI
Celera765,020,398 - 65,042,696 (-)NCBICelera
Cytogenetic Map7q22NCBI
Ywhaz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,047,263 - 16,072,854 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,047,263 - 16,070,506 (-)NCBIChiLan1.0ChiLan1.0
YWHAZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1899,730,393 - 99,765,559 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl899,730,393 - 99,762,990 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0897,560,251 - 97,595,117 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
YWHAZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1132,729,404 - 2,764,422 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,728,046 - 2,764,406 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0132,885,028 - 2,921,415 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl132,884,653 - 2,921,431 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1132,728,699 - 2,765,052 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0132,841,194 - 2,877,738 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0132,857,979 - 2,894,557 (-)NCBIUU_Cfam_GSD_1.0
Ywhaz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530335,018,527 - 35,044,806 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647042,445,412 - 42,470,900 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647042,444,671 - 42,470,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl435,975,508 - 36,009,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1435,975,513 - 36,009,909 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2438,914,372 - 38,942,695 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1895,786,197 - 95,821,270 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl895,788,305 - 95,819,197 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603944,861,087 - 44,896,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhaz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247637,722,275 - 7,723,482 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in YWHAZ
18 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_145690.3(YWHAZ):c.689C>G (p.Ser230Trp) single nucleotide variant Reclassified - variant of unknown significance [RCV000778073]|See cases [RCV001197430]|not provided [RCV001089758]|not specified [RCV000517158] Chr8:100920742 [GRCh38]
Chr8:101932970 [GRCh37]
Chr8:8q22.3
pathogenic|uncertain significance|not provided
GRCh38/hg38 8q22.2-22.3(chr8:100023254-101190270)x3 copy number gain See cases [RCV000050759] Chr8:100023254..101190270 [GRCh38]
Chr8:101035482..102202498 [GRCh37]
Chr8:101104658..102271674 [NCBI36]
Chr8:8q22.2-22.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q22.2-22.3(chr8:99580206-101547228)x1 copy number loss See cases [RCV000137322] Chr8:99580206..101547228 [GRCh38]
Chr8:100592434..102559456 [GRCh37]
Chr8:100661610..102628632 [NCBI36]
Chr8:8q22.2-22.3
likely pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8q22.2-23.1(chr8:100179408-106524667)x1 copy number loss See cases [RCV000141697] Chr8:100179408..106524667 [GRCh38]
Chr8:101191636..107536895 [GRCh37]
Chr8:101260812..107606071 [NCBI36]
Chr8:8q22.2-23.1
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q13.2-24.3(chr8:68912432-146295771)x2 copy number gain See cases [RCV002292707] Chr8:68912432..146295771 [GRCh37]
Chr8:8q13.2-24.3
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q21.2-23.3(chr8:86841154-116518125)x3 copy number gain not provided [RCV000683045] Chr8:86841154..116518125 [GRCh37]
Chr8:8q21.2-23.3
pathogenic
GRCh37/hg19 8q22.2-22.3(chr8:100551211-103676738)x1 copy number loss not provided [RCV000683023] Chr8:100551211..103676738 [GRCh37]
Chr8:8q22.2-22.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
NM_145690.3(YWHAZ):c.615A>C (p.Thr205=) single nucleotide variant not provided [RCV000927973] Chr8:100924018 [GRCh38]
Chr8:101936246 [GRCh37]
Chr8:8q22.3
likely benign
NM_145690.3(YWHAZ):c.157G>A (p.Gly53Arg) single nucleotide variant Reclassified - variant of unknown significance [RCV000778074] Chr8:100948733 [GRCh38]
Chr8:101960961 [GRCh37]
Chr8:8q22.3
pathogenic|uncertain significance
NM_145690.3(YWHAZ):c.434C>T (p.Ser145Leu) single nucleotide variant Reclassified - variant of unknown significance [RCV000778075] Chr8:100924283 [GRCh38]
Chr8:101936511 [GRCh37]
Chr8:8q22.3
pathogenic|uncertain significance
NM_145690.3(YWHAZ):c.40G>T (p.Glu14Ter) single nucleotide variant Reclassified - variant of unknown significance [RCV000778076] Chr8:100948850 [GRCh38]
Chr8:101961078 [GRCh37]
Chr8:8q22.3
pathogenic|uncertain significance
NM_145690.3(YWHAZ):c.687_688dup (p.Ser230fs) duplication Reclassified - variant of unknown significance [RCV000778077] Chr8:100920742..100920743 [GRCh38]
Chr8:101932970..101932971 [GRCh37]
Chr8:8q22.3
pathogenic|uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
NM_145690.3(YWHAZ):c.369A>C (p.Gly123=) single nucleotide variant not provided [RCV000933513] Chr8:100924965 [GRCh38]
Chr8:101937193 [GRCh37]
Chr8:8q22.3
likely benign
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771) copy number gain Polydactyly [RCV002280629] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:84712253-146295771)x3 copy number gain See cases [RCV002285066] Chr8:84712253..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q22.2-22.3(chr8:101532661-102444420) copy number loss not specified [RCV002053789] Chr8:101532661..102444420 [GRCh37]
Chr8:8q22.2-22.3
uncertain significance
GRCh37/hg19 8q13.2-24.3(chr8:70382990-146295771) copy number gain not specified [RCV002053772] Chr8:70382990..146295771 [GRCh37]
Chr8:8q13.2-24.3
pathogenic
NC_000008.10:g.(?_99135566)_(106815766_?)dup duplication Cohen syndrome [RCV001997398] Chr8:99135566..106815766 [GRCh37]
Chr8:8q22.2-23.1
uncertain significance
NM_145690.3(YWHAZ):c.385T>C (p.Leu129=) single nucleotide variant not provided [RCV002124430] Chr8:100924949 [GRCh38]
Chr8:101937177 [GRCh37]
Chr8:8q22.3
likely benign
NM_145690.3(YWHAZ):c.705C>T (p.Asp235=) single nucleotide variant not provided [RCV002173750] Chr8:100920726 [GRCh38]
Chr8:101932954 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.495T>A (p.Pro165=) single nucleotide variant not provided [RCV002194792] Chr8:100924222 [GRCh38]
Chr8:101936450 [GRCh37]
Chr8:8q22.3
likely benign
NM_145690.3(YWHAZ):c.678+18T>G single nucleotide variant not provided [RCV002113369] Chr8:100923937 [GRCh38]
Chr8:101936165 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.582+20C>A single nucleotide variant not provided [RCV002085779] Chr8:100924115 [GRCh38]
Chr8:101936343 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.294+14C>T single nucleotide variant not provided [RCV002188782] Chr8:100948582 [GRCh38]
Chr8:101960810 [GRCh37]
Chr8:8q22.3
likely benign
NM_145690.3(YWHAZ):c.261G>A (p.Glu87=) single nucleotide variant not provided [RCV002112903] Chr8:100948629 [GRCh38]
Chr8:101960857 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.583-5C>T single nucleotide variant not provided [RCV002201966] Chr8:100924055 [GRCh38]
Chr8:101936283 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.679-11T>C single nucleotide variant not provided [RCV002161604] Chr8:100920763 [GRCh38]
Chr8:101932991 [GRCh37]
Chr8:8q22.3
benign
GRCh37/hg19 8q22.1-24.3(chr8:96496503-146295711) copy number gain not provided [RCV002221452] Chr8:96496503..146295711 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
NC_000008.10:g.(?_98358247)_(106815766_?)dup duplication not provided [RCV003122777] Chr8:98358247..106815766 [GRCh37]
Chr8:8q22.1-23.1
uncertain significance
GRCh37/hg19 8q21.12-24.11(chr8:79409349-119040631)x3 copy number gain not provided [RCV002474526] Chr8:79409349..119040631 [GRCh37]
Chr8:8q21.12-24.11
pathogenic
NM_145690.3(YWHAZ):c.323A>G (p.Asn108Ser) single nucleotide variant not provided [RCV003089903] Chr8:100925011 [GRCh38]
Chr8:101937239 [GRCh37]
Chr8:8q22.3
uncertain significance
NM_145690.3(YWHAZ):c.679-14C>T single nucleotide variant not provided [RCV003043913] Chr8:100920766 [GRCh38]
Chr8:101932994 [GRCh37]
Chr8:8q22.3
likely benign
NM_145690.3(YWHAZ):c.570T>G (p.Ser190_Leu191=) single nucleotide variant not provided [RCV002943998] Chr8:100924147 [GRCh38]
Chr8:101936375 [GRCh37]
Chr8:8q22.3
benign
NM_145690.3(YWHAZ):c.264G>A (p.Thr88_Glu89=) single nucleotide variant not provided [RCV002609618] Chr8:100948626 [GRCh38]
Chr8:101960854 [GRCh37]
Chr8:8q22.3
likely benign
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR193Bhsa-miR-193b-3pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;ProteomiFunctional MTI21512034
MIR375hsa-miR-375Mirtarbaseexternal_infoReporter assay;Western blot;qRT-PCR;MicroarrayFunctional MTI20215506
MIR193Bhsa-miR-193b-3pTarbaseexternal_infoReporter GenePOSITIVE
MIR193Bhsa-miR-193b-3pOncomiRDBexternal_infoNANA21512034
MIR375hsa-miR-375Mirecordsexternal_info{changed}NA20215506
MIR375hsa-miR-375OncomiRDBexternal_infoNANA20215506

Predicted Target Of
Summary Value
Count of predictions:7365
Count of miRNA genes:1212
Interacting mature miRNAs:1518
Transcripts:ENST00000353245, ENST00000395948, ENST00000395951, ENST00000395953, ENST00000395956, ENST00000395957, ENST00000395958, ENST00000418997, ENST00000419477, ENST00000437293, ENST00000457309, ENST00000480304, ENST00000492736, ENST00000517727, ENST00000518736, ENST00000521309, ENST00000521328, ENST00000521607, ENST00000522542, ENST00000522819, ENST00000523131, ENST00000523848, ENST00000523938
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-35187  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378101,938,465 - 101,938,594UniSTSGRCh37
Build 368102,007,641 - 102,007,770RGDNCBI36
Celera898,123,503 - 98,123,632RGD
Cytogenetic Map8q23.1UniSTS
HuRef897,136,409 - 97,136,538UniSTS
GeneMap99-GB4 RH Map8440.32UniSTS
Whitehead-RH Map8584.3UniSTS
NCBI RH Map81101.1UniSTS
PMC126239P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378101,932,559 - 101,932,652UniSTSGRCh37
Build 368102,001,735 - 102,001,828RGDNCBI36
Celera898,117,596 - 98,117,689RGD
Cytogenetic Map8q23.1UniSTS
HuRef897,130,506 - 97,130,599UniSTS
PMC150726P7  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8q23.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 4 3 2 52 12
Medium 2428 2949 1720 619 1947 461 4351 2157 3706 415 1396 1596 171 1204 2787 4
Low 7 42 6 5 4 4 2 39 28 2 12 5 4 1 1 2 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001135699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005251061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005251063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011517290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017013810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017013811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017013812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA830489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC018781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC027373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC111951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM783874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ605329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN276619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN276627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR996247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB472116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC298291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ185048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF094937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU794582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU794583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ472215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M86400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S79449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U79277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000353245   ⟹   ENSP00000309503
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,918,686 - 100,953,341 (-)Ensembl
RefSeq Acc Id: ENST00000395948   ⟹   ENSP00000379278
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,603 - 100,952,990 (-)Ensembl
RefSeq Acc Id: ENST00000395951   ⟹   ENSP00000379281
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,630 - 100,950,557 (-)Ensembl
RefSeq Acc Id: ENST00000395953   ⟹   ENSP00000379283
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,587 - 100,951,594 (-)Ensembl
RefSeq Acc Id: ENST00000395956   ⟹   ENSP00000379286
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,918,683 - 100,951,449 (-)Ensembl
RefSeq Acc Id: ENST00000395957   ⟹   ENSP00000379287
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,916,525 - 100,952,983 (-)Ensembl
RefSeq Acc Id: ENST00000395958   ⟹   ENSP00000379288
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,916,523 - 100,952,020 (-)Ensembl
RefSeq Acc Id: ENST00000418997   ⟹   ENSP00000416551
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,948,596 - 100,952,619 (-)Ensembl
RefSeq Acc Id: ENST00000419477   ⟹   ENSP00000395114
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,642 - 100,951,276 (-)Ensembl
RefSeq Acc Id: ENST00000437293   ⟹   ENSP00000394880
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,948,614 - 100,952,883 (-)Ensembl
RefSeq Acc Id: ENST00000457309   ⟹   ENSP00000398599
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,918,579 - 100,952,993 (-)Ensembl
RefSeq Acc Id: ENST00000480304
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,922,438 - 100,951,969 (-)Ensembl
RefSeq Acc Id: ENST00000492736
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,951,956 - 100,953,388 (-)Ensembl
RefSeq Acc Id: ENST00000517727
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,923,987 - 100,950,540 (-)Ensembl
RefSeq Acc Id: ENST00000518736
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,923,985 - 100,951,595 (-)Ensembl
RefSeq Acc Id: ENST00000521309   ⟹   ENSP00000429623
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,919,829 - 100,952,019 (-)Ensembl
RefSeq Acc Id: ENST00000521328   ⟹   ENSP00000429041
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,924,922 - 100,950,996 (-)Ensembl
RefSeq Acc Id: ENST00000521607   ⟹   ENSP00000430058
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,716 - 100,948,900 (-)Ensembl
RefSeq Acc Id: ENST00000522542   ⟹   ENSP00000430072
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,919,829 - 100,948,162 (-)Ensembl
RefSeq Acc Id: ENST00000522819   ⟹   ENSP00000428775
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,920,526 - 100,935,055 (-)Ensembl
RefSeq Acc Id: ENST00000523131   ⟹   ENSP00000428381
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,948,663 - 100,952,604 (-)Ensembl
RefSeq Acc Id: ENST00000523848   ⟹   ENSP00000428860
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,919,062 - 100,924,988 (-)Ensembl
RefSeq Acc Id: ENST00000523938   ⟹   ENSP00000430219
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8100,948,735 - 100,952,552 (-)Ensembl
RefSeq Acc Id: NM_001135699   ⟹   NP_001129171
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,952,995 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,006,117 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,078,695 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001135700   ⟹   NP_001129172
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,951,312 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,004,456 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,077,012 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001135701   ⟹   NP_001129173
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,951,312 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,004,456 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,077,012 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001135702   ⟹   NP_001129174
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,950,571 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,003,696 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,076,269 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003406   ⟹   NP_003397
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,953,382 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
Build 368102,000,090 - 102,034,745 (-)NCBI Archive
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,006,519 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,079,082 (-)NCBI
Sequence:
RefSeq Acc Id: NM_145690   ⟹   NP_663723
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,952,020 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
Build 368102,000,090 - 102,033,447 (-)NCBI Archive
HuRef897,128,746 - 97,163,575 (-)ENTREZGENE
CHM1_18101,971,677 - 102,005,253 (-)NCBI
T2T-CHM13v2.08102,042,222 - 102,077,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005251061   ⟹   XP_005251118
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,953,382 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005251063   ⟹   XP_005251120
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,952,020 (-)NCBI
GRCh378101,930,804 - 101,965,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017013810   ⟹   XP_016869299
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,953,382 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017013811   ⟹   XP_016869300
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,916,523 - 100,953,382 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001129171 (Get FASTA)   NCBI Sequence Viewer  
  NP_001129172 (Get FASTA)   NCBI Sequence Viewer  
  NP_001129173 (Get FASTA)   NCBI Sequence Viewer  
  NP_001129174 (Get FASTA)   NCBI Sequence Viewer  
  NP_003397 (Get FASTA)   NCBI Sequence Viewer  
  NP_663723 (Get FASTA)   NCBI Sequence Viewer  
  XP_005251118 (Get FASTA)   NCBI Sequence Viewer  
  XP_005251120 (Get FASTA)   NCBI Sequence Viewer  
  XP_016869299 (Get FASTA)   NCBI Sequence Viewer  
  XP_016869300 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36446 (Get FASTA)   NCBI Sequence Viewer  
  AAC52052 (Get FASTA)   NCBI Sequence Viewer  
  AAD14300 (Get FASTA)   NCBI Sequence Viewer  
  AAH03623 (Get FASTA)   NCBI Sequence Viewer  
  AAH51814 (Get FASTA)   NCBI Sequence Viewer  
  AAH63824 (Get FASTA)   NCBI Sequence Viewer  
  AAH68456 (Get FASTA)   NCBI Sequence Viewer  
  AAH72426 (Get FASTA)   NCBI Sequence Viewer  
  AAH73141 (Get FASTA)   NCBI Sequence Viewer  
  AAH83508 (Get FASTA)   NCBI Sequence Viewer  
  AAH99904 (Get FASTA)   NCBI Sequence Viewer  
  AAI01484 (Get FASTA)   NCBI Sequence Viewer  
  AAI08282 (Get FASTA)   NCBI Sequence Viewer  
  AAI11952 (Get FASTA)   NCBI Sequence Viewer  
  ABD14427 (Get FASTA)   NCBI Sequence Viewer  
  ABO15003 (Get FASTA)   NCBI Sequence Viewer  
  ACJ13636 (Get FASTA)   NCBI Sequence Viewer  
  ACJ13637 (Get FASTA)   NCBI Sequence Viewer  
  ACV87190 (Get FASTA)   NCBI Sequence Viewer  
  BAF82634 (Get FASTA)   NCBI Sequence Viewer  
  BAF98758 (Get FASTA)   NCBI Sequence Viewer  
  BAH11832 (Get FASTA)   NCBI Sequence Viewer  
  BAH12451 (Get FASTA)   NCBI Sequence Viewer  
  EAW91823 (Get FASTA)   NCBI Sequence Viewer  
  EAW91824 (Get FASTA)   NCBI Sequence Viewer  
  EAW91825 (Get FASTA)   NCBI Sequence Viewer  
  EAW91826 (Get FASTA)   NCBI Sequence Viewer  
  EAW91827 (Get FASTA)   NCBI Sequence Viewer  
  EAW91828 (Get FASTA)   NCBI Sequence Viewer  
  EAW91829 (Get FASTA)   NCBI Sequence Viewer  
  P63104 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_003397   ⟸   NM_003406
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129171   ⟸   NM_001135699
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_663723   ⟸   NM_145690
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129172   ⟸   NM_001135700
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129173   ⟸   NM_001135701
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129174   ⟸   NM_001135702
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005251118   ⟸   XM_005251061
- Peptide Label: isoform X1
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005251120   ⟸   XM_005251063
- Peptide Label: isoform X1
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016869299   ⟸   XM_017013810
- Peptide Label: isoform X1
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016869300   ⟸   XM_017013811
- Peptide Label: isoform X1
- UniProtKB: Q86V33 (UniProtKB/Swiss-Prot),   P63104 (UniProtKB/Swiss-Prot),   D0PNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000429623   ⟸   ENST00000521309
RefSeq Acc Id: ENSP00000429041   ⟸   ENST00000521328
RefSeq Acc Id: ENSP00000398599   ⟸   ENST00000457309
RefSeq Acc Id: ENSP00000430058   ⟸   ENST00000521607
RefSeq Acc Id: ENSP00000430072   ⟸   ENST00000522542
RefSeq Acc Id: ENSP00000416551   ⟸   ENST00000418997
RefSeq Acc Id: ENSP00000395114   ⟸   ENST00000419477
RefSeq Acc Id: ENSP00000428775   ⟸   ENST00000522819
RefSeq Acc Id: ENSP00000430219   ⟸   ENST00000523938
RefSeq Acc Id: ENSP00000428860   ⟸   ENST00000523848
RefSeq Acc Id: ENSP00000428381   ⟸   ENST00000523131
RefSeq Acc Id: ENSP00000309503   ⟸   ENST00000353245
RefSeq Acc Id: ENSP00000379278   ⟸   ENST00000395948
RefSeq Acc Id: ENSP00000379287   ⟸   ENST00000395957
RefSeq Acc Id: ENSP00000379288   ⟸   ENST00000395958
RefSeq Acc Id: ENSP00000379286   ⟸   ENST00000395956
RefSeq Acc Id: ENSP00000379283   ⟸   ENST00000395953
RefSeq Acc Id: ENSP00000379281   ⟸   ENST00000395951
RefSeq Acc Id: ENSP00000394880   ⟸   ENST00000437293
Protein Domains
14-3-3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63104-F1-model_v2 AlphaFold P63104 1-245 view protein structure

Promoters
RGD ID:7213901
Promoter ID:EPDNEW_H12696
Type:initiation region
Name:YWHAZ_3
Description:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activationprotein zeta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12698  EPDNEW_H12697  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,951,502 - 100,951,562EPDNEW
RGD ID:7213905
Promoter ID:EPDNEW_H12697
Type:initiation region
Name:YWHAZ_1
Description:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activationprotein zeta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12696  EPDNEW_H12698  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,952,017 - 100,952,077EPDNEW
RGD ID:7213903
Promoter ID:EPDNEW_H12698
Type:initiation region
Name:YWHAZ_2
Description:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activationprotein zeta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12696  EPDNEW_H12697  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388100,953,379 - 100,953,439EPDNEW
RGD ID:6815654
Promoter ID:HG_MRA:15979
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:DQ185048
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,005,359 - 102,005,859 (-)MPROMDB
RGD ID:6813559
Promoter ID:HG_ACW:78184
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:YWHAZ.OAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,005,836 - 102,006,336 (-)MPROMDB
RGD ID:6807164
Promoter ID:HG_KWN:61817
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001135702
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,031,789 - 102,032,289 (-)MPROMDB
RGD ID:6806667
Promoter ID:HG_KWN:61818
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000395953,   ENST00000395956,   ENST00000395957,   NM_001135699,   NM_001135701,   NM_003406,   NM_145690,   OTTHUMT00000259021,   OTTHUMT00000259022,   OTTHUMT00000259023,   OTTHUMT00000259024,   UC003YJY.1,   UC010MBQ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,033,341 - 102,034,862 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12855 AgrOrtholog
COSMIC YWHAZ COSMIC
Ensembl Genes ENSG00000164924 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000309503 ENTREZGENE
  ENSP00000309503.3 UniProtKB/Swiss-Prot
  ENSP00000379278.2 UniProtKB/TrEMBL
  ENSP00000379281 ENTREZGENE
  ENSP00000379281.3 UniProtKB/Swiss-Prot
  ENSP00000379283 ENTREZGENE
  ENSP00000379283.2 UniProtKB/Swiss-Prot
  ENSP00000379286 ENTREZGENE
  ENSP00000379286.3 UniProtKB/Swiss-Prot
  ENSP00000379287 ENTREZGENE
  ENSP00000379287.2 UniProtKB/Swiss-Prot
  ENSP00000379288 ENTREZGENE
  ENSP00000379288.2 UniProtKB/Swiss-Prot
  ENSP00000394880.1 UniProtKB/TrEMBL
  ENSP00000395114 ENTREZGENE
  ENSP00000395114.2 UniProtKB/Swiss-Prot
  ENSP00000398599 ENTREZGENE
  ENSP00000398599.1 UniProtKB/Swiss-Prot
  ENSP00000416551.1 UniProtKB/TrEMBL
  ENSP00000428381.1 UniProtKB/TrEMBL
  ENSP00000428775.1 UniProtKB/TrEMBL
  ENSP00000428860.1 UniProtKB/TrEMBL
  ENSP00000429041.1 UniProtKB/TrEMBL
  ENSP00000429623.1 UniProtKB/TrEMBL
  ENSP00000430058.1 UniProtKB/TrEMBL
  ENSP00000430072.1 UniProtKB/Swiss-Prot
  ENSP00000430219.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000353245 ENTREZGENE
  ENST00000353245.7 UniProtKB/Swiss-Prot
  ENST00000395948.6 UniProtKB/TrEMBL
  ENST00000395951 ENTREZGENE
  ENST00000395951.7 UniProtKB/Swiss-Prot
  ENST00000395953 ENTREZGENE
  ENST00000395953.6 UniProtKB/Swiss-Prot
  ENST00000395956 ENTREZGENE
  ENST00000395956.7 UniProtKB/Swiss-Prot
  ENST00000395957 ENTREZGENE
  ENST00000395957.6 UniProtKB/Swiss-Prot
  ENST00000395958 ENTREZGENE
  ENST00000395958.6 UniProtKB/Swiss-Prot
  ENST00000418997.1 UniProtKB/TrEMBL
  ENST00000419477 ENTREZGENE
  ENST00000419477.6 UniProtKB/Swiss-Prot
  ENST00000437293.5 UniProtKB/TrEMBL
  ENST00000457309 ENTREZGENE
  ENST00000457309.2 UniProtKB/Swiss-Prot
  ENST00000521309.5 UniProtKB/TrEMBL
  ENST00000521328.5 UniProtKB/TrEMBL
  ENST00000521607.5 UniProtKB/TrEMBL
  ENST00000522542.5 UniProtKB/Swiss-Prot
  ENST00000522819.5 UniProtKB/TrEMBL
  ENST00000523131.1 UniProtKB/TrEMBL
  ENST00000523848.5 UniProtKB/TrEMBL
  ENST00000523938.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000164924 GTEx
HGNC ID HGNC:12855 ENTREZGENE
Human Proteome Map YWHAZ Human Proteome Map
InterPro 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 7534 ENTREZGENE
OMIM 601288 OMIM
PANTHER 14-3-3 PROTEIN ZETA/DELTA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18860 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37444 PharmGKB
PIRSF 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1433_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 1433Z_HUMAN UniProtKB/Swiss-Prot
  B0AZS6_HUMAN UniProtKB/TrEMBL
  B7Z2E6_HUMAN UniProtKB/TrEMBL
  D0PNI1 ENTREZGENE, UniProtKB/TrEMBL
  E5RGE1_HUMAN UniProtKB/TrEMBL
  E5RIR4_HUMAN UniProtKB/TrEMBL
  E7ESK7_HUMAN UniProtKB/TrEMBL
  E7EVZ2_HUMAN UniProtKB/TrEMBL
  E7EX29_HUMAN UniProtKB/TrEMBL
  E9PD24_HUMAN UniProtKB/TrEMBL
  H0YB80_HUMAN UniProtKB/TrEMBL
  P63104 ENTREZGENE
  Q86V33 ENTREZGENE
UniProt Secondary A8K1N0 UniProtKB/Swiss-Prot
  B7Z465 UniProtKB/Swiss-Prot
  P29213 UniProtKB/Swiss-Prot
  P29312 UniProtKB/Swiss-Prot
  Q32P43 UniProtKB/Swiss-Prot
  Q5XJ08 UniProtKB/Swiss-Prot
  Q6GPI2 UniProtKB/Swiss-Prot
  Q6IN74 UniProtKB/Swiss-Prot
  Q6NUR9 UniProtKB/Swiss-Prot
  Q6P3U9 UniProtKB/Swiss-Prot
  Q86V33 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 YWHAZ  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta  YWHAD  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide  Data Merged 737654 PROVISIONAL
2016-03-07 YWHAZ  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta  Symbol and/or name change 5135510 APPROVED
2013-12-10 YWHAZ  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide  Symbol and/or name change 5135510 APPROVED
2011-08-16 YWHAZ  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide  YWHAZ  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide  Symbol and/or name change 5135510 APPROVED