Ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) Chinchilla lanigera
Analyze
Symbol: Ywhaz
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
RGD ID: 9016806
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); phosphoserine residue binding (ortholog); INVOLVED IN angiogenesis (ortholog); ERK1 and ERK2 cascade (ortholog); establishment of Golgi localization (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; histone modification pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); childhood absence epilepsy (ortholog); FOUND IN cell leading edge (ortholog); cytosol (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein zeta/delta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,047,263 - 16,072,854 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,047,263 - 16,070,506 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
Ywhaz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,047,263 - 16,072,854 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,047,263 - 16,070,506 (-)NCBIChiLan1.0ChiLan1.0
YWHAZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388100,916,523 - 100,953,382 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8100,916,523 - 100,953,388 (-)EnsemblGRCh38hg38GRCh38
GRCh378101,928,751 - 101,965,610 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,000,090 - 102,034,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 348102,000,089 - 102,033,447NCBI
Celera898,115,836 - 98,150,667 (-)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef897,128,746 - 97,163,575 (-)NCBIHuRef
CHM1_18101,971,677 - 102,006,519 (-)NCBICHM1_1
T2T-CHM13v2.08102,042,222 - 102,079,082 (-)NCBIT2T-CHM13v2.0
Ywhaz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391536,770,505 - 36,803,228 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1536,771,014 - 36,797,173 (-)EnsemblGRCm39 Ensembl
GRCm381536,770,261 - 36,802,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1536,770,770 - 36,796,929 (-)EnsemblGRCm38mm10GRCm38
MGSCv371536,700,016 - 36,724,293 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361536,715,359 - 36,738,833 (-)NCBIMGSCv36mm8
Celera1537,392,750 - 37,416,932 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
Ywhaz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2767,941,353 - 67,963,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl767,940,017 - 67,963,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx769,829,731 - 69,852,029 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0772,032,344 - 72,054,642 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0771,900,221 - 71,922,519 (-)NCBIRnor_WKY
Rnor_6.0775,573,553 - 75,598,295 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl775,574,967 - 75,597,276 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0775,719,688 - 75,744,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,283,825 - 72,306,126 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1772,304,554 - 72,327,161 (-)NCBI
Celera765,020,398 - 65,042,696 (-)NCBICelera
Cytogenetic Map7q22NCBI
YWHAZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1893,806,633 - 93,841,446 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0897,560,251 - 97,595,117 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1899,730,393 - 99,765,559 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl899,730,393 - 99,762,990 (-)Ensemblpanpan1.1panPan2
YWHAZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1132,729,404 - 2,764,422 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,728,046 - 2,764,406 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0132,885,028 - 2,921,415 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl132,884,653 - 2,921,431 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1132,728,699 - 2,765,052 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0132,841,194 - 2,877,738 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0132,857,979 - 2,894,557 (-)NCBIUU_Cfam_GSD_1.0
Ywhaz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530335,018,527 - 35,044,806 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647042,445,412 - 42,470,900 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647042,444,671 - 42,470,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl435,975,508 - 36,009,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1435,975,513 - 36,009,909 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2438,914,372 - 38,942,695 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1895,786,197 - 95,821,270 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl895,788,305 - 95,819,197 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603944,861,087 - 44,896,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhaz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247637,722,275 - 7,723,482 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006181   ⟹   ENSCLAP00000006078
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541716,047,263 - 16,072,854 (-)Ensembl
RefSeq Acc Id: XM_013512810   ⟹   XP_013368264
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541716,047,263 - 16,070,506 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013368264 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013368264   ⟸   XM_013512810
- UniProtKB: A0A8C2UZS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000006078   ⟸   ENSCLAT00000006181
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004303 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000006078 ENTREZGENE
  ENSCLAP00000006078.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006181 ENTREZGENE
  ENSCLAT00000006181.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/TrEMBL
NCBI Gene Ywhaz ENTREZGENE
PANTHER 14-3-3 PROTEIN ZETA/DELTA UniProtKB/TrEMBL
  PTHR18860 UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/TrEMBL
PIRSF 14-3-3 UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/TrEMBL
  1433_2 UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/TrEMBL
UniProt A0A8C2UZS6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ywhaz  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta  Symbol and/or name change 5135510 APPROVED
2015-08-25 Ywhaz  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide  Symbol and/or name change 5135510 APPROVED