Gene: Dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2) Rattus norvegicus
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Symbol: Dyrk2
Name: dual specificity tyrosine phosphorylation regulated kinase 2
Description: ENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dual specificity tyrosine-phosphorylation-regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; LOC314862
Orthologs:
Homo sapiens (human) : DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2)
Canis lupus familiaris (dog) : DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0761,785,423 - 61,816,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0761,775,902 - 61,807,168 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4758,114,127 - 58,126,547 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1758,138,697 - 58,149,260 (-)NCBI
Celera751,116,337 - 51,128,757 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Dyrk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE



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