Gene: Aes (amino-terminal enhancer of split) Rattus norvegicus
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Symbol: Aes
Name: amino-terminal enhancer of split
Description: ENCODES a protein that exhibits identical protein binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cellular response to extracellular stimulus (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH Myocardial Ischemia (ortholog); FOUND IN nucleus; INTERACTS WITH bisphenol A; ethanol; nefazodone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amino enhancer of split; Grg; Grg-5; groucho-related protein 5; MGC124620; R-esp1; related to Drosophila groucho; related to Drosophila groucho gene
Orthologs:
Homo sapiens (human) : AES (amino-terminal enhancer of split)  HGNC  Alliance
Mus musculus (house mouse) : Aes (amino-terminal enhancer of split)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aes (amino-terminal enhancer of split)
Pan paniscus (bonobo/pygmy chimpanzee) : AES (amino-terminal enhancer of split)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aes (amino-terminal enhancer of split)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0711,012,843 - 11,018,156 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,180,239 - 11,187,223 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,616,545 - 9,621,697 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.179,616,544 - 9,621,684 (-)NCBI
Celera76,334,418 - 6,339,570 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aes
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2731
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE