Zfpm2 (zinc finger protein, multitype 2) - Rat Genome Database

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Gene: Zfpm2 (zinc finger protein, multitype 2) Rattus norvegicus
Analyze
Symbol: Zfpm2
Name: zinc finger protein, multitype 2
RGD ID: 1306021
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; transcription coactivator activity; and transcription corepressor activity. Predicted to be involved in several processes, including cardiac chamber morphogenesis; positive regulation of male gonad development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including circulatory system development; in utero embryonic development; and regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FOG-2; zinc finger protein ZFPM2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)Ensembl
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Celera768,728,223 - 69,158,299 (+)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
male germ cell nucleus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,ISO)

References

References - curated
# Reference Title Reference Citation
1. AML1-FOG2 fusion protein in myelodysplasia. Chan EM, etal., Blood. 2005 Jun 1;105(11):4523-6. Epub 2005 Feb 10.
2. Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2. Clabby ML, etal., J Biol Chem 2003 Feb 21;278(8):5760-7.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension. Kumarasamy S, etal., Nat Commun. 2015 Feb 17;6:6252. doi: 10.1038/ncomms7252.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Pizzuti A, etal., Hum Mutat. 2003 Nov;22(5):372-7.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. Roche AE, etal., J Mol Cell Cardiol. 2008 Feb;44(2):352-60. Epub 2007 Nov 12.
Additional References at PubMed
PMID:9927675   PMID:10225993   PMID:10438528   PMID:10888889   PMID:10892744   PMID:12213678   PMID:12606418   PMID:15220332   PMID:15766748   PMID:16103912   PMID:17445768   PMID:19301398  
PMID:20206639   PMID:20705609   PMID:20807224   PMID:22267003  


Genomics

Comparative Map Data
Zfpm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)Ensembl
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Celera768,728,223 - 69,158,299 (+)NCBICelera
Cytogenetic Map7q31NCBI
ZFPM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388105,318,438 - 105,804,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8104,590,733 - 105,804,539 (+)EnsemblGRCh38hg38GRCh38
GRCh378106,330,666 - 106,816,767 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368106,400,323 - 106,885,943 (+)NCBINCBI36hg18NCBI36
Build 348106,400,322 - 106,885,941NCBI
Celera8102,518,281 - 103,003,726 (+)NCBI
Cytogenetic Map8q23.1NCBI
HuRef8101,532,803 - 102,138,045 (+)NCBIHuRef
CHM1_18106,371,762 - 106,857,264 (+)NCBICHM1_1
T2T-CHM13v2.08106,445,857 - 106,932,108 (+)NCBI
Zfpm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391540,518,438 - 40,967,988 (+)NCBIGRCm39mm39
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)Ensembl
GRCm381540,655,042 - 41,104,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371540,486,588 - 40,936,138 (+)NCBIGRCm37mm9NCBIm37
MGSCv361540,485,116 - 40,934,666 (+)NCBImm8
Celera1541,140,194 - 41,582,164 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.74NCBI
Zfpm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541728,920,210 - 29,269,271 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541728,931,428 - 29,268,778 (+)NCBIChiLan1.0ChiLan1.0
ZFPM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18104,193,343 - 104,577,698 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8104,023,062 - 104,576,688 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08101,872,850 - 102,430,622 (+)NCBIMhudiblu_PPA_v0panPan3
ZFPM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1136,435,368 - 6,796,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl136,336,794 - 6,796,322 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha136,442,921 - 6,803,153 (+)NCBI
ROS_Cfam_1.0136,588,050 - 7,045,717 (+)NCBI
ROS_Cfam_1.0 Ensembl136,587,518 - 7,044,757 (+)Ensembl
UMICH_Zoey_3.1136,451,443 - 6,811,875 (+)NCBI
UNSW_CanFamBas_1.0136,571,226 - 6,931,950 (+)NCBI
UU_Cfam_GSD_1.0136,646,836 - 7,007,257 (+)NCBI
Zfpm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530331,006,795 - 31,431,557 (-)NCBI
SpeTri2.0NW_00493647038,432,894 - 38,857,656 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFPM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl431,606,751 - 32,094,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1431,607,968 - 31,996,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2434,232,973 - 34,242,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2434,441,657 - 34,641,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFPM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18100,138,867 - 100,620,355 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBIVero_WHO_p1.0
Zfpm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476321,388,244 - 21,707,953 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476321,388,060 - 21,708,969 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D7Rat22  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4776,615,342 - 76,615,501UniSTSRGSC3.4
RGSC_v3.4776,615,341 - 76,615,501RGDRGSC3.4
RGSC_v3.1776,636,071 - 76,636,231RGD
Celera769,120,095 - 69,120,250UniSTS
RH 3.4 Map7620.3RGD
RH 3.4 Map7620.3UniSTS
RH 2.0 Map7478.6RGD
SHRSP x BN Map745.53RGD
FHH x ACI Map736.75RGD
Cytogenetic Map7q22-q31UniSTS
D7Rat142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,788,963 - 71,789,091 (+)MAPPERmRatBN7.2
Rnor_6.0779,629,118 - 79,629,245NCBIRnor6.0
Rnor_5.0779,648,702 - 79,648,829UniSTSRnor5.0
RGSC_v3.4776,323,357 - 76,323,874RGDRGSC3.4
RGSC_v3.4776,323,578 - 76,323,705UniSTSRGSC3.4
RGSC_v3.1776,344,308 - 76,344,435RGD
Celera768,837,793 - 68,837,920UniSTS
RH 3.4 Map7621.8UniSTS
RH 3.4 Map7621.8RGD
SHRSP x BN Map745.53UniSTS
SHRSP x BN Map745.53RGD
Cytogenetic Map7q22-q31UniSTS
D7Got234  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,906,963 - 71,907,149 (+)MAPPERmRatBN7.2
Rnor_6.0779,745,450 - 79,745,635NCBIRnor6.0
Rnor_5.0779,765,034 - 79,765,219UniSTSRnor5.0
RGSC_v3.4776,442,431 - 76,442,616UniSTSRGSC3.4
Celera768,949,245 - 68,949,428UniSTS
Cytogenetic Map7q22-q31UniSTS
AW532229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,806,271 - 71,806,429 (+)MAPPERmRatBN7.2
Rnor_6.0779,646,431 - 79,646,589NCBIRnor6.0
Rnor_5.0779,666,015 - 79,666,173UniSTSRnor5.0
RGSC_v3.4776,340,888 - 76,341,045UniSTSRGSC3.4
Celera768,855,075 - 68,855,232UniSTS
RH 3.4 Map7621.5UniSTS
Cytogenetic Map7q22-q31UniSTS
PMC303372P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2772,115,403 - 72,115,888 (+)MAPPERmRatBN7.2
Rnor_6.0779,963,604 - 79,964,088NCBIRnor6.0
Rnor_5.0779,975,879 - 79,976,363UniSTSRnor5.0
RGSC_v3.4776,653,642 - 76,654,126UniSTSRGSC3.4
Celera769,157,498 - 69,157,982UniSTS
Cytogenetic Map7q22-q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)77084011872474897Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)77084011872474897Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:199
Count of miRNA genes:114
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000029419
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 4 4 4 50 4 24 1
Low 17 47 35 15 35 7 9 24 29 17 10 7
Below cutoff 3 6 2 4 2 1 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029419   ⟹   ENSRNOP00000035072
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)Ensembl
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)Ensembl
RefSeq Acc Id: NM_001130501   ⟹   NP_001123973
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2771,678,880 - 72,116,205 (+)NCBI
Rnor_6.0779,471,277 - 79,964,405 (+)NCBI
Rnor_5.0779,491,886 - 79,976,680 (+)NCBI
RGSC_v3.4776,210,472 - 76,654,443 (+)RGD
Celera768,728,223 - 69,158,299 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079162   ⟹   XP_038935090
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2771,678,658 - 72,116,209 (+)NCBI
RefSeq Acc Id: XM_039079163   ⟹   XP_038935091
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2771,959,241 - 72,116,209 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001123973 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935090 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935091 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16331 (Get FASTA)   NCBI Sequence Viewer  
  EDM16332 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001123973   ⟸   NM_001130501
- Sequence:
RefSeq Acc Id: ENSRNOP00000035072   ⟸   ENSRNOT00000029419
RefSeq Acc Id: XP_038935090   ⟸   XM_039079162
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935091   ⟸   XM_039079163
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A0R1-F1-model_v2 AlphaFold D4A0R1 1-1090 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 76501610 76501611 C G snv ACI/EurMcwi (MCW), SR/JrHsd (MCW), ACI/N (KNAW), BUF/N (KNAW), COP/CrCrl (MCW & UW), LCR/1Mco (UMich), SR/JrHsd (ICL), HCR/1Mco (UMich), LCR/2Mco (UMich), HCR/2Mco (UMich), GK/Ox (ICL), ACI/EurMcwi (ICL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306021 AgrOrtholog
BioCyc Gene G2FUF-33537 BioCyc
Ensembl Genes ENSRNOG00000004109 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000035072 ENTREZGENE
  ENSRNOP00000035072.7 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029419 ENTREZGENE
  ENSRNOT00000029419.7 UniProtKB/TrEMBL
InterPro FOG UniProtKB/TrEMBL
  ZF_CCHC_FOG UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene 314930 ENTREZGENE
PANTHER PTHR12958 UniProtKB/TrEMBL
PhenoGen Zfpm2 PhenoGen
PROSITE ZF_CCHC_FOG UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt D4A0R1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Zfpm2  zinc finger protein, multitype 2   Zfpm2_predicted  zinc finger protein, multitype 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Zfpm2_predicted  zinc finger protein, multitype 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED