Ano4 (anoctamin 4) - Rat Genome Database

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Gene: Ano4 (anoctamin 4) Rattus norvegicus
Analyze
Symbol: Ano4
Name: anoctamin 4
RGD ID: 1310252
Description: Predicted to enable intracellular calcium activated chloride channel activity and phospholipid scramblase activity. Predicted to be involved in chloride transmembrane transport. Predicted to act upstream of or within calcium activated phospholipid scrambling and establishment of localization in cell. Predicted to be active in plasma membrane. Orthologous to human ANO4 (anoctamin 4); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: anoctamin-4; chromosome alignment-maintaining phosphoprotein 1-like; LOC102554867; LOC299714; Tmem16d; transmembrane protein 16D; transmembrane protein 16D (eight membrane-spanning domains); uncharacterized LOC102554867
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2723,329,015 - 23,738,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl723,329,070 - 23,738,434 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx725,323,573 - 25,647,372 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,486,107 - 27,809,928 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,263,320 - 27,587,119 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,492,017 - 30,025,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,492,016 - 29,701,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,125,460 - 30,125,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0729,593,754 - 29,766,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,641,745 - 25,971,720 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,661,960 - 25,796,163 (-)NCBI
Celera720,483,792 - 20,799,037 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22075693   PMID:22946059   PMID:23532839  


Genomics

Comparative Map Data
Ano4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2723,329,015 - 23,738,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl723,329,070 - 23,738,434 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx725,323,573 - 25,647,372 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,486,107 - 27,809,928 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,263,320 - 27,587,119 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,492,017 - 30,025,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,492,016 - 29,701,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,125,460 - 30,125,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0729,593,754 - 29,766,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,641,745 - 25,971,720 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,661,960 - 25,796,163 (-)NCBI
Celera720,483,792 - 20,799,037 (-)NCBICelera
Cytogenetic Map7q13NCBI
ANO4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812100,717,261 - 101,128,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12100,717,526 - 101,128,641 (+)EnsemblGRCh38hg38GRCh38
GRCh3712101,188,554 - 101,522,419 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,712,716 - 100,046,539 (+)NCBINCBI36Build 36hg18NCBI36
Build 341299,691,052 - 100,024,876NCBI
Celera12100,853,681 - 101,187,742 (+)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1298,249,077 - 98,582,590 (+)NCBIHuRef
CHM1_112101,154,362 - 101,488,557 (+)NCBICHM1_1
T2T-CHM13v2.012100,678,611 - 101,090,362 (+)NCBIT2T-CHM13v2.0
Ano4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391088,784,794 - 89,181,059 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1088,784,856 - 89,180,624 (-)EnsemblGRCm39 Ensembl
GRCm381088,948,932 - 89,345,205 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1088,948,994 - 89,344,762 (-)EnsemblGRCm38mm10GRCm38
MGSCv371088,411,739 - 88,720,535 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361088,378,793 - 88,687,589 (-)NCBIMGSCv36mm8
Celera1090,924,174 - 91,240,555 (-)NCBICelera
Cytogenetic Map10C1- C2NCBI
cM Map1044.42NCBI
Ano4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540536,375,115 - 36,715,889 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540536,350,013 - 36,715,740 (+)NCBIChiLan1.0ChiLan1.0
ANO4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan112108,854,283 - 109,191,378 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01298,295,875 - 98,709,918 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112101,700,830 - 102,113,378 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,885,088 - 102,111,806 (+)Ensemblpanpan1.1panPan2
ANO4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,740,496 - 40,149,039 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,740,337 - 40,149,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1540,113,594 - 40,517,497 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01540,398,697 - 40,802,967 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1540,388,012 - 40,802,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11539,655,353 - 40,059,580 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01539,762,286 - 40,167,016 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01540,036,702 - 40,440,957 (+)NCBIUU_Cfam_GSD_1.0
Ano4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494519,799,573 - 20,183,598 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649212,809,987 - 13,000,661 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649212,810,004 - 13,000,647 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,052,958 - 83,489,433 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1583,052,070 - 83,489,523 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2587,091,739 - 87,321,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANO4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11196,013,244 - 96,415,282 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1196,094,823 - 96,413,721 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037148,609,881 - 149,020,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247506,740,017 - 7,103,732 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247506,738,343 - 7,103,767 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ano4
2849 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:317
Count of miRNA genes:193
Interacting mature miRNAs:228
Transcripts:ENSRNOT00000009084
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat

Markers in Region
D7Rat152  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2723,605,754 - 23,605,887 (+)MAPPERmRatBN7.2
Rnor_6.0729,763,835 - 29,763,969NCBIRnor6.0
Rnor_5.0729,867,142 - 29,867,276UniSTSRnor5.0
RGSC_v3.4725,926,022 - 25,926,156UniSTSRGSC3.4
RGSC_v3.4725,926,004 - 25,926,410RGDRGSC3.4
RGSC_v3.4725,925,586 - 25,925,720UniSTSRGSC3.4
RGSC_v3.1725,946,293 - 25,946,427RGD
Celera720,753,262 - 20,753,396UniSTS
RH 3.4 Map7122.8RGD
RH 3.4 Map7122.8UniSTS
RH 2.0 Map7132.8RGD
SHRSP x BN Map717.91RGD
Cytogenetic Map7q13UniSTS
RH144298  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2723,438,064 - 23,438,220 (+)MAPPERmRatBN7.2
Rnor_6.0729,599,433 - 29,599,588NCBIRnor6.0
Rnor_5.0729,700,787 - 29,700,942UniSTSRnor5.0
RGSC_v3.4725,753,981 - 25,754,136UniSTSRGSC3.4
Celera720,589,288 - 20,589,443UniSTS
RH 3.4 Map7120.46UniSTS
Cytogenetic Map7q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 31 7
Low 29 7 2 4 4 37 18 30 11 4
Below cutoff 2 14 22 13 9 13 4 6 6 12 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000009084   ⟹   ENSRNOP00000009084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,329,070 - 23,651,732 (-)Ensembl
Rnor_6.0 Ensembl729,492,066 - 29,701,586 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089269   ⟹   ENSRNOP00000071454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,329,070 - 23,738,434 (-)Ensembl
Rnor_6.0 Ensembl729,492,016 - 29,701,721 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109574   ⟹   ENSRNOP00000079757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,329,070 - 23,651,938 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117276   ⟹   ENSRNOP00000089175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,329,070 - 23,738,434 (-)Ensembl
RefSeq Acc Id: NM_001106778   ⟹   NP_001100248
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,652,850 (-)NCBI
Rnor_6.0729,492,066 - 30,024,536 (-)NCBI
Rnor_5.0729,593,754 - 29,766,992 (-)NCBI
Rnor_5.0730,125,460 - 30,125,825 (-)NCBI
RGSC_v3.4725,641,745 - 25,971,720 (-)RGD
Celera720,483,792 - 20,799,037 (-)RGD
Sequence:
RefSeq Acc Id: NM_001395725   ⟹   NP_001382654
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,652,850 (-)NCBI
RefSeq Acc Id: XM_008765230   ⟹   XP_008763452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,463,185 (-)NCBI
Rnor_6.0729,492,017 - 29,624,078 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594725   ⟹   XP_017450214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,331,874 - 23,652,850 (-)NCBI
Rnor_6.0729,492,017 - 30,024,470 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594726   ⟹   XP_017450215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,738,417 (-)NCBI
Rnor_6.0729,492,017 - 29,870,041 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594729   ⟹   XP_017450218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,331,874 - 23,652,851 (-)NCBI
Rnor_6.0729,492,017 - 30,025,587 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078688   ⟹   XP_038934616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,738,422 (-)NCBI
RefSeq Acc Id: XM_039078689   ⟹   XP_038934617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,331,874 - 23,738,422 (-)NCBI
RefSeq Acc Id: XM_039078690   ⟹   XP_038934618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,738,423 (-)NCBI
RefSeq Acc Id: XM_039078691   ⟹   XP_038934619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,463,182 (-)NCBI
RefSeq Acc Id: XM_039078692   ⟹   XP_038934620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2723,329,015 - 23,463,185 (-)NCBI
RefSeq Acc Id: NP_001100248   ⟸   NM_001106778
- Peptide Label: isoform 2 precursor
- UniProtKB: F1M4U7 (UniProtKB/TrEMBL),   A6IFQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763452   ⟸   XM_008765230
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017450218   ⟸   XM_017594729
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZNA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450214   ⟸   XM_017594725
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K0I0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450215   ⟸   XM_017594726
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0I0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009084   ⟸   ENSRNOT00000009084
RefSeq Acc Id: ENSRNOP00000071454   ⟸   ENSRNOT00000089269
RefSeq Acc Id: XP_038934618   ⟸   XM_039078690
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934616   ⟸   XM_039078688
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AKC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934620   ⟸   XM_039078692
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038934619   ⟸   XM_039078691
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038934617   ⟸   XM_039078689
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000089175   ⟸   ENSRNOT00000117276
RefSeq Acc Id: ENSRNOP00000079757   ⟸   ENSRNOT00000109574
RefSeq Acc Id: NP_001382654   ⟸   NM_001395725
- Peptide Label: isoform 1
Protein Domains
Anoctamin dimerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0I0-F1-model_v2 AlphaFold A0A0G2K0I0 1-955 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310252 AgrOrtholog
BioCyc Gene G2FUF-34496 BioCyc
Ensembl Genes ENSRNOG00000006841 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009084 ENTREZGENE
  ENSRNOT00000009084.8 UniProtKB/TrEMBL
  ENSRNOT00000089269 ENTREZGENE
  ENSRNOT00000089269.2 UniProtKB/TrEMBL
  ENSRNOT00000109574 ENTREZGENE
  ENSRNOT00000109574.1 UniProtKB/TrEMBL
  ENSRNOT00000117276 ENTREZGENE
  ENSRNOT00000117276.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
KEGG Report rno:299714 UniProtKB/TrEMBL
NCBI Gene 299714 ENTREZGENE
PANTHER DUF590 UniProtKB/TrEMBL
  PTHR12308:SF28 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
PhenoGen Ano4 PhenoGen
RatGTEx ENSRNOG00000006841 RatGTEx
UniProt A0A0G2K0I0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKC4 ENTREZGENE, UniProtKB/TrEMBL
  A6IFQ7 ENTREZGENE, UniProtKB/TrEMBL
  F1M4U7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ano4  anoctamin 4  LOC102554867  uncharacterized LOC102554867  Data merged from RGD:7499244 737654 PROVISIONAL
2013-12-17 LOC102554867  uncharacterized LOC102554867      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-25 Ano4  anoctamin 4  Tmem16d  transmembrane protein 16D (eight membrane-spanning domains)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Tmem16d  transmembrane protein 16D (eight membrane-spanning domains)  Tmem16d_predicted  transmembrane protein 16D (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tmem16d_predicted  transmembrane protein 16D (predicted)    transmembrane protein 16D (eight membrane-spanning domains) (predicted)  Name updated 1299863 APPROVED
2005-01-12 Tmem16d_predicted  transmembrane protein 16D (eight membrane-spanning domains) (predicted)      Symbol and Name status set to approved 70820 APPROVED