Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Embryo Loss | | ISO | UBE2N (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:16738225 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Embryo Loss | | ISO | UBE2N (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:16738225 | |
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# | Reference Title | Reference Citation |
1. | ATM protein kinase: the linchpin of cellular defenses to stress. | Bhatti S, etal., Cell Mol Life Sci. 2011 Sep;68(18):2977-3006. doi: 10.1007/s00018-011-0683-9. Epub 2011 May 2. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Pathogen recognition by the innate immune system. | Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34. |
4. | Defective ubiquitination of cerebral proteins in Alzheimer's disease. | Lopez Salon M, etal., J Neurosci Res 2000 Oct 15;62(2):302-10. |
5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
6. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
7. | Double-strand break repair: 53BP1 comes into focus. | Panier S and Boulton SJ, Nat Rev Mol Cell Biol. 2014 Jan;15(1):7-18. doi: 10.1038/nrm3719. Epub 2013 Dec 11. |
8. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
9. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
10. | Control of ubiquitination of proteins in rat tissues by ubiquitin conjugating enzymes and isopeptidases. | Rajapurohitam V, etal., Am J Physiol Endocrinol Metab 2002 Apr;282(4):E739-45. |
11. | GOA pipeline | RGD automated data pipeline |
12. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
13. | Comprehensive gene review and curation | RGD comprehensive gene curation |
14. | TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme. | Verstrepen L, etal., Cell Mol Life Sci. 2008 Oct;65(19):2964-78. |
15. | Interleukin-1 (IL-1) pathway. | Weber A, etal., Sci Signal. 2010 Jan 19;3(105):cm1. doi: 10.1126/scisignal.3105cm1. |
PMID:12039045 | PMID:12477932 | PMID:14406273 | PMID:14695475 | PMID:15125833 | PMID:15383616 | PMID:15489334 | PMID:16122702 | PMID:16129784 | PMID:16307917 | PMID:17349954 | PMID:18410486 |
PMID:19340006 | PMID:20061386 | PMID:20458337 | PMID:21512573 | PMID:22424771 | PMID:22681889 | PMID:22797923 | PMID:22871113 | PMID:23376485 | PMID:23533145 | PMID:25936802 | PMID:28039360 |
PMID:29097665 | PMID:31006531 |
Ube2n (Rattus norvegicus - Norway rat) |
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UBE2N (Homo sapiens - human) |
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Ube2n (Mus musculus - house mouse) |
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Ube2n (Chinchilla lanigera - long-tailed chinchilla) |
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UBE2N (Pan paniscus - bonobo/pygmy chimpanzee) |
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UBE2N (Canis lupus familiaris - dog) |
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Ube2n (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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UBE2N (Sus scrofa - pig) |
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UBE2N (Chlorocebus sabaeus - green monkey) |
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Ube2n (Heterocephalus glaber - naked mole-rat) |
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Variants in Ube2n
176 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH142361 |
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RH125323 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_053928 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_063262876 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB032739 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC124896 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC090072 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473960 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000089874 ⟹ ENSRNOP00000071283 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_053928 ⟹ NP_446380 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063262876 ⟹ XP_063118946 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_446380 | (Get FASTA) | NCBI Sequence Viewer |
XP_063118946 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH90072 | (Get FASTA) | NCBI Sequence Viewer |
BAB20414 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16856 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000071283 | ||
ENSRNOP00000071283.1 | |||
ENSRNOP00055007651 | |||
ENSRNOP00060005780 | |||
ENSRNOP00065014979 | |||
GenBank Protein | Q9EQX9 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_446380 ⟸ NM_053928 |
- UniProtKB: | Q9EQX9 (UniProtKB/Swiss-Prot), A6IG42 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000071283 ⟸ ENSRNOT00000089874 |
RefSeq Acc Id: | XP_063118946 ⟸ XM_063262876 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9EQX9-F1-model_v2 | AlphaFold | Q9EQX9 | 1-152 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13695159 | ||||||||
Promoter ID: | EPDNEW_R5684 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Ube2n_2 | ||||||||
Description: | ubiquitin-conjugating enzyme E2N | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R5685 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 13695160 | ||||||||
Promoter ID: | EPDNEW_R5685 | ||||||||
Type: | initiation region | ||||||||
Name: | Ube2n_1 | ||||||||
Description: | ubiquitin-conjugating enzyme E2N | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R5684 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621096 | AgrOrtholog |
BioCyc Gene | G2FUF-34333 | BioCyc |
BioCyc Pathway | PWY-7511 [protein ubiquitination] | BioCyc |
BioCyc Pathway Image | PWY-7511 | BioCyc |
Ensembl Genes | ENSRNOG00000058053 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
ENSRNOG00055006099 | UniProtKB/Swiss-Prot | |
ENSRNOG00060004628 | UniProtKB/Swiss-Prot | |
ENSRNOG00065012014 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000089874 | ENTREZGENE |
ENSRNOT00000089874.2 | UniProtKB/Swiss-Prot | |
ENSRNOT00055009893 | UniProtKB/Swiss-Prot | |
ENSRNOT00060007715 | UniProtKB/Swiss-Prot | |
ENSRNOT00065019543 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 3.10.110.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7113593 | IMAGE-MGC_LOAD |
InterPro | UBQ-conjugat_E2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UBQ-conjugating_AS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBQ-conjugating_enzyme/RWD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:116725 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:93937 | IMAGE-MGC_LOAD |
NCBI Gene | 116725 | ENTREZGENE |
PANTHER | UBIQUITIN-CONJUGATING ENZYME | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UBIQUITIN-CONJUGATING ENZYME E2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | UQ_con | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Ube2n | PhenoGen |
PROSITE | UBC_1 | UniProtKB/TrEMBL |
UBC_2 | UniProtKB/TrEMBL | |
UBIQUITIN_CONJUGAT_1 | UniProtKB/Swiss-Prot | |
UBIQUITIN_CONJUGAT_2 | UniProtKB/Swiss-Prot | |
RatGTEx | ENSRNOG00000058053 | RatGTEx |
ENSRNOG00055006099 | RatGTEx | |
ENSRNOG00060004628 | RatGTEx | |
ENSRNOG00065012014 | RatGTEx | |
SMART | UBCc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF54495 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A6IG42 | ENTREZGENE, UniProtKB/TrEMBL |
Q9EQX9 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2011-08-01 | Ube2n | ubiquitin-conjugating enzyme E2N | Ube2n | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2010-05-25 | Ube2n | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | Ube2n | ubiquitin-conjugating enzyme E2N | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-07-08 | Ube2n | ubiquitin-conjugating enzyme E2N | ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) | Name updated | 1299863 | APPROVED | |
2002-08-07 | Ube2n | ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_function | interacts with specific E3s; may mediate substrate selectivity | 724779 |