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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RGD:735866 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SLC6A15 mRNA | CTD | PMID:24763279 | (2,4,5-trichlorophenoxy)acetic acid | decreases expression | ISO | RGD:735867 | 6480464 | 2 more ... | CTD | PMID:18579281 | 1,1-dichloroethene | decreases expression | ISO | RGD:735867 | 6480464 | vinylidene chloride results in decreased expression of SLC6A15 mRNA | CTD | PMID:26682919 | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | multiple interactions | ISO | RGD:735867 | 6480464 | [Citalopram co-treated with Caffeine] results in decreased expression of SLC6A15 mRNA | CTD | PMID:29107002 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:735867 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC6A15 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC6A15 mRNA | CTD | PMID:33387578 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | RGD:735866 | 6480464 | 2 more ... | CTD | PMID:26705709 | aflatoxin B1 | decreases methylation | ISO | RGD:735866 | 6480464 | Aflatoxin B1 results in decreased methylation of SLC6A15 gene | CTD | PMID:27153756 | agomelatine | multiple interactions | ISO | RGD:735867 | 6480464 | [Caffeine co-treated with agomelatine] results in decreased expression of SLC6A15 mRNA | CTD | PMID:29882086 | all-trans-retinoic acid | decreases expression | ISO | RGD:735866 | 6480464 | Tretinoin results in decreased expression of SLC6A15 mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SLC6A15 mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | RGD:735866 | 6480464 | aristolochic acid I results in decreased expression of SLC6A15 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | RGD:735867 | 6480464 | Benzo(a)pyrene results in decreased expression of SLC6A15 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | RGD:735866 | 6480464 | Benzo(a)pyrene affects the methylation of SLC6A15 5' UTR, Benzo(a)pyrene affects the methylation of SLC6A15 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:735866 | 6480464 | Benzo(a)pyrene results in increased methylation of SLC6A15 exon | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | RGD:735866 | 6480464 | bisphenol A results in decreased expression of SLC6A15 mRNA | CTD | PMID:20678512 | bisphenol A | multiple interactions | ISO | RGD:735866 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SLC6A15 gene | CTD | PMID:31601247 | bisphenol A | increases methylation | ISO | RGD:735866 | 6480464 | bisphenol A results in increased methylation of SLC6A15 gene | CTD | PMID:31601247 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SLC6A15 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | RGD:735866 | 6480464 | bisphenol A results in increased expression of SLC6A15 mRNA | CTD | PMID:27685785, PMID:29275510 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC6A15 mRNA | CTD | PMID:25181051, PMID:31129395 | bleomycin A2 | decreases expression | ISO | RGD:735867 | 6480464 | Bleomycin results in decreased expression of SLC6A15 mRNA | CTD | PMID:30825431 | bleomycin A2 | multiple interactions | ISO | RGD:735867 | 6480464 | Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA], lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] | CTD | PMID:30825431 | butanal | increases expression | ISO | RGD:735866 | 6480464 | butyraldehyde results in increased expression of SLC6A15 mRNA | CTD | PMID:26079696 | caffeine | multiple interactions | ISO | RGD:735867 | 6480464 | [Caffeine co-treated with agomelatine] results in decreased expression of SLC6A15 mRNA more ... | CTD | PMID:29107002, PMID:29882086 | cannabidiol | multiple interactions | ISO | RGD:735867 | 6480464 | Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] | CTD | PMID:30825431 | chloroprene | increases expression | ISO | RGD:735867 | 6480464 | Chloroprene results in increased expression of SLC6A15 mRNA | CTD | PMID:23125180 | cisplatin | multiple interactions | ISO | RGD:735866 | 6480464 | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of SLC6A15 mRNA] | CTD | PMID:21858171 | cisplatin | decreases expression | ISO | RGD:735866 | 6480464 | Cisplatin results in decreased expression of SLC6A15 mRNA | CTD | PMID:27392435 | citalopram | multiple interactions | ISO | RGD:735867 | 6480464 | [Citalopram co-treated with Caffeine] results in decreased expression of SLC6A15 mRNA | CTD | PMID:29107002 | copper(II) sulfate | decreases expression | ISO | RGD:735867 | 6480464 | Copper Sulfate results in decreased expression of SLC6A15 mRNA | CTD | PMID:18579281 | corticosterone | multiple interactions | ISO | RGD:735867 | 6480464 | Edaravone inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA], Paroxetine inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA] | CTD | PMID:31344373 | corticosterone | decreases expression | ISO | RGD:735867 | 6480464 | Corticosterone results in decreased expression of SLC6A15 mRNA | CTD | PMID:31344373 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SLC6A15 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases methylation | ISO | RGD:735866 | 6480464 | Cyclosporine results in decreased methylation of SLC6A15 promoter | CTD | PMID:27989131 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA | CTD | PMID:18636392 | dorsomorphin | multiple interactions | ISO | RGD:735866 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | edaravone | multiple interactions | ISO | RGD:735867 | 6480464 | Edaravone inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA] | CTD | PMID:31344373 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SLC6A15 mRNA | CTD | PMID:29391264 | fluoxetine | multiple interactions | ISO | RGD:735867 | 6480464 | [Fluoxetine co-treated with Caffeine] results in decreased expression of SLC6A15 mRNA | CTD | PMID:29107002 | folic acid | decreases expression | ISO | RGD:735867 | 6480464 | Folic Acid results in decreased expression of SLC6A15 mRNA | CTD | PMID:25629700 | fulvestrant | multiple interactions | ISO | RGD:735866 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SLC6A15 gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLC6A15 mRNA | CTD | PMID:33387578 | hydrazine | decreases expression | ISO | RGD:735867 | 6480464 | hydrazine results in decreased expression of SLC6A15 mRNA | CTD | PMID:15282401 | Licochalcone B | decreases expression | ISO | RGD:735866 | 6480464 | licochalcone B results in decreased expression of SLC6A15 mRNA | CTD | PMID:33647349 | mercury dibromide | decreases expression | ISO | RGD:735866 | 6480464 | mercuric bromide results in decreased expression of SLC6A15 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | RGD:735866 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC6A15 mRNA | CTD | PMID:27188386 | methylmercury chloride | decreases expression | ISO | RGD:735866 | 6480464 | methylmercuric chloride results in decreased expression of SLC6A15 mRNA | CTD | PMID:23179753, PMID:27188386 | methylmercury chloride | increases expression | ISO | RGD:735866 | 6480464 | methylmercuric chloride results in increased expression of SLC6A15 mRNA | CTD | PMID:28001369 | mianserin | multiple interactions | ISO | RGD:735867 | 6480464 | [Caffeine co-treated with Mianserin] results in decreased expression of SLC6A15 mRNA | CTD | PMID:29882086 | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:735866 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of SLC6A15 mRNA | CTD | PMID:24810058 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA | CTD | PMID:18636392 | ozone | multiple interactions | ISO | RGD:735867 | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SLC6A15 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | RGD:735867 | 6480464 | Acetaminophen results in increased expression of SLC6A15 mRNA | CTD | PMID:17585979 | paroxetine | multiple interactions | ISO | RGD:735867 | 6480464 | Paroxetine inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA] | CTD | PMID:31344373 | PD 0325901 | multiple interactions | ISO | RGD:735866 | 6480464 | [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of SLC6A15 mRNA | CTD | PMID:25119042 | PD 0325901 | decreases expression | ISO | RGD:735866 | 6480464 | mirdametinib results in decreased expression of SLC6A15 mRNA | CTD | PMID:25119042 | pentanal | increases expression | ISO | RGD:735866 | 6480464 | pentanal results in increased expression of SLC6A15 mRNA | CTD | PMID:26079696 | phenylmercury acetate | decreases expression | ISO | RGD:735866 | 6480464 | Phenylmercuric Acetate results in decreased expression of SLC6A15 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:735866 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC6A15 mRNA | CTD | PMID:27188386 | pioglitazone | multiple interactions | ISO | RGD:735867 | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A15 mRNA | CTD | PMID:27935865 | piroxicam | multiple interactions | ISO | RGD:735866 | 6480464 | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of SLC6A15 mRNA] | CTD | PMID:21858171 | piroxicam | decreases expression | ISO | RGD:735866 | 6480464 | Piroxicam results in decreased expression of SLC6A15 mRNA | CTD | PMID:21858171 | potassium chromate | increases expression | ISO | RGD:735866 | 6480464 | potassium chromate(VI) results in increased expression of SLC6A15 mRNA | CTD | PMID:22714537 | propanal | increases expression | ISO | RGD:735866 | 6480464 | propionaldehyde results in increased expression of SLC6A15 mRNA | CTD | PMID:26079696 | sarin | decreases expression | ISO | RGD:735866 | 6480464 | Sarin results in decreased expression of SLC6A15 mRNA | CTD | PMID:19522546 | SB 431542 | multiple interactions | ISO | RGD:735866 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | RGD:735866 | 6480464 | Silicon Dioxide analog results in increased expression of SLC6A15 mRNA | CTD | PMID:25895662 | silicon dioxide | decreases expression | ISO | RGD:735866 | 6480464 | Silicon Dioxide results in decreased expression of SLC6A15 mRNA | CTD | PMID:25351596 | silver atom | decreases expression | ISO | RGD:735867 | 6480464 | Silver results in decreased expression of SLC6A15 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:735867 | 6480464 | Silver results in decreased expression of SLC6A15 mRNA | CTD | PMID:27131904 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of SLC6A15 mRNA | CTD | PMID:27257137 | temozolomide | decreases expression | ISO | RGD:735866 | 6480464 | Temozolomide results in decreased expression of SLC6A15 mRNA | CTD | PMID:31758290 | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of SLC6A15 mRNA | CTD | PMID:21515302 | titanium dioxide | decreases expression | ISO | RGD:735867 | 6480464 | titanium dioxide results in decreased expression of SLC6A15 mRNA | CTD | PMID:29264374 | tributylstannane | decreases expression | EXP | | 6480464 | tributyltin results in decreased expression of SLC6A15 mRNA | CTD | PMID:31129395 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC6A15 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | RGD:735866 | 6480464 | trichostatin A results in increased expression of SLC6A15 mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | RGD:735866 | 6480464 | Triclosan results in increased expression of SLC6A15 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | ISO | RGD:735866 | 6480464 | Valproic Acid affects the expression of SLC6A15 mRNA | CTD | PMID:23179753, PMID:25979313 | valproic acid | decreases expression | ISO | RGD:735866 | 6480464 | Valproic Acid results in decreased expression of SLC6A15 mRNA | CTD | PMID:28001369 | valproic acid | increases expression | ISO | RGD:735866 | 6480464 | Valproic Acid results in increased expression of SLC6A15 mRNA | CTD | PMID:24935251, PMID:27188386 | vorinostat | multiple interactions | ISO | RGD:735866 | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC6A15 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | RGD:735866 | 6480464 | vorinostat results in increased expression of SLC6A15 mRNA | CTD | PMID:26272509 | |