UBXN1 (UBX domain protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: UBXN1 (UBX domain protein 1) Homo sapiens
Analyze
Symbol: UBXN1
Name: UBX domain protein 1
RGD ID: 1606294
HGNC Page HGNC:18402
Description: Enables several functions, including enzyme binding activity; polyubiquitin modification-dependent protein binding activity; and proteasome regulatory particle binding activity. Involved in negative regulation of protein metabolic process. Located in cytosol; endoplasmic reticulum; and nucleoplasm. Part of VCP-NPL4-UFD1 AAA ATPase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2B28; SAKS1; SAPK substrate protein 1; UBA/UBX 33.3 kDa protein; UBX domain-containing protein 1; UBXD10
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,676,500 - 62,679,073 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,676,498 - 62,679,117 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,443,972 - 62,446,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,200,548 - 62,203,103 (-)NCBINCBI36Build 36hg18NCBI36
Celera1159,773,551 - 59,776,106 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,772,838 - 58,775,393 (-)NCBIHuRef
CHM1_11162,327,085 - 62,329,640 (-)NCBICHM1_1
T2T-CHM13v2.01162,665,920 - 62,668,532 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10942595   PMID:12477932   PMID:12838346   PMID:14702039   PMID:14744259   PMID:15342556   PMID:15362974   PMID:15489334   PMID:15761153   PMID:15944415   PMID:17207965   PMID:17353931  
PMID:18330356   PMID:18775313   PMID:19285159   PMID:19615732   PMID:20351172   PMID:21135095   PMID:21145461   PMID:21873635   PMID:22658674   PMID:22863883   PMID:22902628   PMID:22939629  
PMID:23463506   PMID:23545497   PMID:25416956   PMID:25681446   PMID:25959826   PMID:25963833   PMID:26186194   PMID:26344197   PMID:26389662   PMID:26618866   PMID:26972000   PMID:27107014  
PMID:27432908   PMID:27785701   PMID:28152074   PMID:28190767   PMID:28380382   PMID:28514442   PMID:28515276   PMID:29229926   PMID:29291351   PMID:29467282   PMID:29540532   PMID:29685906  
PMID:29987050   PMID:30463901   PMID:31091453   PMID:31494268   PMID:31694235   PMID:31699778   PMID:31723608   PMID:31980649   PMID:32039147   PMID:32249768   PMID:32296183   PMID:32416067  
PMID:32457219   PMID:32640226   PMID:32687490   PMID:33277362   PMID:33462405   PMID:33545068   PMID:33754075   PMID:33961781   PMID:33966597   PMID:33990333   PMID:34011540   PMID:34237211  
PMID:34246306   PMID:34599178   PMID:34917906   PMID:35253629   PMID:35256949   PMID:35552390   PMID:35676246   PMID:35831314   PMID:35944360   PMID:36215168   PMID:36688959   PMID:36736316  
PMID:37931956  


Genomics

Comparative Map Data
UBXN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,676,500 - 62,679,073 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,676,498 - 62,679,117 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,443,972 - 62,446,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,200,548 - 62,203,103 (-)NCBINCBI36Build 36hg18NCBI36
Celera1159,773,551 - 59,776,106 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,772,838 - 58,775,393 (-)NCBIHuRef
CHM1_11162,327,085 - 62,329,640 (-)NCBICHM1_1
T2T-CHM13v2.01162,665,920 - 62,668,532 (-)NCBIT2T-CHM13v2.0
Ubxn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,848,912 - 8,853,030 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,848,860 - 8,853,227 (+)EnsemblGRCm39 Ensembl
GRCm38198,871,548 - 8,875,666 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,871,496 - 8,875,863 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,946,049 - 8,950,146 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,938,604 - 8,942,701 (+)NCBIMGSCv36mm8
Celera198,632,231 - 8,636,264 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.88NCBI
Ubxn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,194,418 - 215,198,343 (+)NCBIGRCr8
mRatBN7.21205,765,309 - 205,769,234 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,745,120 - 205,816,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,174,101 - 214,177,761 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,208,841 - 221,212,517 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,901,691 - 213,905,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,067,953 - 225,071,944 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,068,009 - 225,071,945 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,005,529 - 232,009,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,541,002 - 211,544,682 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1203,278,239 - 203,281,917 (+)NCBICelera
Cytogenetic Map1q43NCBI
Ubxn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599526,966 - 529,735 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599526,792 - 529,825 (+)NCBIChiLan1.0ChiLan1.0
UBXN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,903,014 - 63,906,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,945,716 - 64,948,311 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,033,304 - 58,035,893 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,386,795 - 61,389,404 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,386,797 - 61,389,404 (-)Ensemblpanpan1.1panPan2
UBXN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,977,937 - 53,982,108 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,978,062 - 53,982,111 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,582,976 - 52,587,154 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,029,832 - 55,034,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,029,965 - 55,034,222 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,126,075 - 54,130,447 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,701,299 - 53,705,487 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,496,856 - 54,501,245 (+)NCBIUU_Cfam_GSD_1.0
Ubxn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,471,145 - 10,474,117 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581584,315 - 591,612 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581584,519 - 587,863 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBXN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,072,968 - 9,075,594 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,072,549 - 9,075,595 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,418,740 - 8,421,335 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBXN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,228,944 - 11,231,549 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,228,135 - 11,231,459 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,562,873 - 108,565,478 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubxn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,179,584 - 1,182,180 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,179,498 - 1,182,445 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UBXN1
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q12.3(chr11:62433886-63096003)x3 copy number gain See cases [RCV000053620] Chr11:62433886..63096003 [GRCh38]
Chr11:62201358..62863475 [GRCh37]
Chr11:61957934..62620051 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh38/hg38 11q12.3(chr11:62452571-62862781)x3 copy number gain See cases [RCV000053621] Chr11:62452571..62862781 [GRCh38]
Chr11:62220043..62630253 [GRCh37]
Chr11:61976619..62386829 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh38/hg38 11q12.3(chr11:62562836-62840570)x3 copy number gain See cases [RCV000134807] Chr11:62562836..62840570 [GRCh38]
Chr11:62330308..62608042 [GRCh37]
Chr11:62086884..62364618 [NCBI36]
Chr11:11q12.3		 uncertain significance
GRCh38/hg38 11q12.3(chr11:62249520-62946093)x3 copy number gain See cases [RCV000138411] Chr11:62249520..62946093 [GRCh38]
Chr11:62016992..62713565 [GRCh37]
Chr11:61773568..62470141 [NCBI36]
Chr11:11q12.3		 pathogenic
GRCh37/hg19 11q12.3(chr11:61840997-62987330)x1 copy number loss See cases [RCV000448355] Chr11:61840997..62987330 [GRCh37]
Chr11:11q12.3		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q12.2-12.3(chr11:60385382-62456278)x3 copy number gain not provided [RCV001006412] Chr11:60385382..62456278 [GRCh37]
Chr11:11q12.2-12.3		 uncertain significance
GRCh37/hg19 11q12.3(chr11:62314663-62788240)x3 copy number gain not provided [RCV000849841] Chr11:62314663..62788240 [GRCh37]
Chr11:11q12.3		 uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
NC_000011.9:g.(?_62380754)_(62472984_?)dup duplication Larsen-like syndrome, B3GAT3 type [RCV001918889] Chr11:62380754..62472984 [GRCh37]
Chr11:11q12.3		 uncertain significance
NC_000011.9:g.(?_58916346)_(64972349_?)dup duplication Leukocyte adhesion deficiency 3 [RCV003113394]|not provided [RCV003113393] Chr11:58916346..64972349 [GRCh37]
Chr11:11q12.1-13.1		 uncertain significance|no classifications from unflagged records
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_001286077.2(UBXN1):c.697C>G (p.Arg233Gly) single nucleotide variant Inborn genetic diseases [RCV002902575] Chr11:62676960 [GRCh38]
Chr11:62444432 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.283A>G (p.Thr95Ala) single nucleotide variant Inborn genetic diseases [RCV002684325] Chr11:62678346 [GRCh38]
Chr11:62445818 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.245G>T (p.Gly82Val) single nucleotide variant Inborn genetic diseases [RCV002761757] Chr11:62678384 [GRCh38]
Chr11:62445856 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.628G>A (p.Glu210Lys) single nucleotide variant Inborn genetic diseases [RCV002707965] Chr11:62677541 [GRCh38]
Chr11:62445013 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.692G>A (p.Arg231Gln) single nucleotide variant Inborn genetic diseases [RCV002989633] Chr11:62676965 [GRCh38]
Chr11:62444437 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.504C>G (p.Ile168Met) single nucleotide variant Inborn genetic diseases [RCV002920868] Chr11:62677811 [GRCh38]
Chr11:62445283 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.19C>G (p.Leu7Val) single nucleotide variant Inborn genetic diseases [RCV003204415] Chr11:62678905 [GRCh38]
Chr11:62446377 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.691C>T (p.Arg231Trp) single nucleotide variant Inborn genetic diseases [RCV003203246] Chr11:62676966 [GRCh38]
Chr11:62444438 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.641G>C (p.Cys214Ser) single nucleotide variant Inborn genetic diseases [RCV003179034] Chr11:62677528 [GRCh38]
Chr11:62445000 [GRCh37]
Chr11:11q12.3		 uncertain significance
NM_001286077.2(UBXN1):c.844+61G>A single nucleotide variant Inborn genetic diseases [RCV003362250] Chr11:62676752 [GRCh38]
Chr11:62444224 [GRCh37]
Chr11:11q12.3		 uncertain significance
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
NM_001286077.2(UBXN1):c.221-14TTGT[2] microsatellite not provided [RCV003395877] Chr11:62678411..62678414 [GRCh38]
Chr11:62445883..62445886 [GRCh37]
Chr11:11q12.3		 likely benign
NM_001286077.2(UBXN1):c.177C>T (p.Ile59=) single nucleotide variant not provided [RCV003395878] Chr11:62678538 [GRCh38]
Chr11:62446010 [GRCh37]
Chr11:11q12.3		 likely benign
NM_001286077.2(UBXN1):c.745G>C (p.Glu249Gln) single nucleotide variant not provided [RCV003395876] Chr11:62676912 [GRCh38]
Chr11:62444384 [GRCh37]
Chr11:11q12.3		 likely benign
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3 copy number gain not specified [RCV003986918] Chr11:50398499..63924462 [GRCh37]
Chr11:11p11.12-q13.1		 likely pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR30Ehsa-miR-30e-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:3329
Count of miRNA genes:927
Interacting mature miRNAs:1119
Transcripts:ENST00000294119, ENST00000301935, ENST00000436354, ENST00000524762, ENST00000525004, ENST00000525717, ENST00000526919, ENST00000527421, ENST00000528907, ENST00000529640, ENST00000531056, ENST00000531625, ENST00000532904, ENST00000533000, ENST00000533476, ENST00000533908, ENST00000534176
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH79660  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,444,022 - 62,444,355UniSTSGRCh37
Build 361162,200,598 - 62,200,931RGDNCBI36
Celera1159,773,601 - 59,773,934RGD
Cytogenetic Map11q12.3UniSTS
HuRef1158,772,888 - 58,773,221UniSTS
RH125269  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,444,351 - 62,444,475UniSTSGRCh37
Build 361162,200,927 - 62,201,051RGDNCBI36
Celera1159,773,930 - 59,774,054RGD
HuRef1158,773,217 - 58,773,341UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 2
Medium 2439 2986 1725 623 1951 464 4357 2192 3734 418 1458 1613 175 1 1204 2788 6 2
Low 5 1 1 1 5 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005274033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI498746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX961874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX961876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI855821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP329601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M68864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000294119   ⟹   ENSP00000294119
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,498 - 62,679,055 (-)Ensembl
RefSeq Acc Id: ENST00000301935   ⟹   ENSP00000303991
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,500 - 62,679,073 (-)Ensembl
RefSeq Acc Id: ENST00000436354
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,678,209 - 62,679,095 (-)Ensembl
RefSeq Acc Id: ENST00000524762
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,980 - 62,679,080 (-)Ensembl
RefSeq Acc Id: ENST00000525004
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,897 - 62,678,537 (-)Ensembl
RefSeq Acc Id: ENST00000525717
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,517 - 62,679,067 (-)Ensembl
RefSeq Acc Id: ENST00000526919
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,677,538 - 62,679,010 (-)Ensembl
RefSeq Acc Id: ENST00000527421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,981 - 62,679,065 (-)Ensembl
RefSeq Acc Id: ENST00000528907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,677,918 - 62,679,073 (-)Ensembl
RefSeq Acc Id: ENST00000529640   ⟹   ENSP00000435964
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,504 - 62,679,065 (-)Ensembl
RefSeq Acc Id: ENST00000531056
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,678,089 - 62,679,077 (-)Ensembl
RefSeq Acc Id: ENST00000531625
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,678,444 - 62,679,073 (-)Ensembl
RefSeq Acc Id: ENST00000532904
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,498 - 62,679,058 (-)Ensembl
RefSeq Acc Id: ENST00000533000   ⟹   ENSP00000432189
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,499 - 62,677,983 (-)Ensembl
RefSeq Acc Id: ENST00000533476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,501 - 62,679,073 (-)Ensembl
RefSeq Acc Id: ENST00000533908
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,677,805 - 62,679,058 (-)Ensembl
RefSeq Acc Id: ENST00000534176   ⟹   ENSP00000435625
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,613 - 62,679,081 (-)Ensembl
RefSeq Acc Id: ENST00000616865   ⟹   ENSP00000478250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1162,676,499 - 62,679,117 (-)Ensembl
RefSeq Acc Id: NM_001286077   ⟹   NP_001273006
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,676,500 - 62,679,073 (-)NCBI
HuRef1158,772,836 - 58,775,455 (-)NCBI
CHM1_11162,327,083 - 62,329,702 (-)NCBI
T2T-CHM13v2.01162,665,920 - 62,668,493 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286078   ⟹   NP_001273007
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,676,500 - 62,679,073 (-)NCBI
HuRef1158,772,836 - 58,775,455 (-)NCBI
CHM1_11162,327,083 - 62,329,702 (-)NCBI
T2T-CHM13v2.01162,665,920 - 62,668,493 (-)NCBI
Sequence:
RefSeq Acc Id: NM_015853   ⟹   NP_056937
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,676,500 - 62,679,073 (-)NCBI
GRCh371162,443,972 - 62,446,554 (-)NCBI
Build 361162,200,548 - 62,203,103 (-)NCBI Archive
Celera1159,773,551 - 59,776,106 (-)RGD
HuRef1158,772,836 - 58,775,455 (-)NCBI
CHM1_11162,327,083 - 62,329,702 (-)NCBI
T2T-CHM13v2.01162,665,920 - 62,668,493 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017017874   ⟹   XP_016873363
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,676,500 - 62,679,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054369044   ⟹   XP_054225019
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01162,665,920 - 62,668,532 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001273006 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273007 (Get FASTA)   NCBI Sequence Viewer  
  NP_056937 (Get FASTA)   NCBI Sequence Viewer  
  XP_016873363 (Get FASTA)   NCBI Sequence Viewer  
  XP_054225019 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36396 (Get FASTA)   NCBI Sequence Viewer  
  AAH00902 (Get FASTA)   NCBI Sequence Viewer  
  AAH01372 (Get FASTA)   NCBI Sequence Viewer  
  AAH32689 (Get FASTA)   NCBI Sequence Viewer  
  AAH40129 (Get FASTA)   NCBI Sequence Viewer  
  BAG51430 (Get FASTA)   NCBI Sequence Viewer  
  BAG60188 (Get FASTA)   NCBI Sequence Viewer  
  BAG62250 (Get FASTA)   NCBI Sequence Viewer  
  BAG64510 (Get FASTA)   NCBI Sequence Viewer  
  BAH14383 (Get FASTA)   NCBI Sequence Viewer  
  CAF06446 (Get FASTA)   NCBI Sequence Viewer  
  CAF06447 (Get FASTA)   NCBI Sequence Viewer  
  CAH05541 (Get FASTA)   NCBI Sequence Viewer  
  CAH05542 (Get FASTA)   NCBI Sequence Viewer  
  EAW74061 (Get FASTA)   NCBI Sequence Viewer  
  EAW74062 (Get FASTA)   NCBI Sequence Viewer  
  EAW74063 (Get FASTA)   NCBI Sequence Viewer  
  EAW74064 (Get FASTA)   NCBI Sequence Viewer  
  EAW74065 (Get FASTA)   NCBI Sequence Viewer  
  EAW74066 (Get FASTA)   NCBI Sequence Viewer  
  EAW74067 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000294119
  ENSP00000294119.2
  ENSP00000303991
  ENSP00000303991.5
  ENSP00000432189.1
  ENSP00000435625
  ENSP00000435625.1
  ENSP00000435964.1
  ENSP00000478250
  ENSP00000478250.1
GenBank Protein Q04323 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_056937   ⟸   NM_015853
- Peptide Label: isoform 1
- UniProtKB: E9PJ81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273007   ⟸   NM_001286078
- Peptide Label: isoform 3
- UniProtKB: A0A087WTZ5 (UniProtKB/TrEMBL),   B4E0P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273006   ⟸   NM_001286077
- Peptide Label: isoform 2
- UniProtKB: Q9BV93 (UniProtKB/Swiss-Prot),   Q9BVV5 (UniProtKB/Swiss-Prot),   Q04323 (UniProtKB/Swiss-Prot),   E9PJ81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016873363   ⟸   XM_017017874
- Peptide Label: isoform X1
- UniProtKB: Q9BV93 (UniProtKB/Swiss-Prot),   Q9BVV5 (UniProtKB/Swiss-Prot),   Q04323 (UniProtKB/Swiss-Prot),   E9PJ81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000294119   ⟸   ENST00000294119
RefSeq Acc Id: ENSP00000432189   ⟸   ENST00000533000
RefSeq Acc Id: ENSP00000435625   ⟸   ENST00000534176
RefSeq Acc Id: ENSP00000478250   ⟸   ENST00000616865
RefSeq Acc Id: ENSP00000303991   ⟸   ENST00000301935
RefSeq Acc Id: ENSP00000435964   ⟸   ENST00000529640
RefSeq Acc Id: XP_054225019   ⟸   XM_054369044
- Peptide Label: isoform X1
- UniProtKB: Q9BV93 (UniProtKB/Swiss-Prot),   Q04323 (UniProtKB/Swiss-Prot),   Q9BVV5 (UniProtKB/Swiss-Prot),   E9PJ81 (UniProtKB/TrEMBL)
Protein Domains
UBA   UBX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q04323-F1-model_v2 AlphaFold Q04323 1-297 view protein structure

Promoters
RGD ID:6789506
Promoter ID:HG_KWN:13119
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_015853,   UC001NUK.2,   UC001NUL.1,   UC001NUM.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361162,202,831 - 62,203,331 (-)MPROMDB
RGD ID:7220683
Promoter ID:EPDNEW_H16088
Type:initiation region
Name:UBXN1_1
Description:UBX domain protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16089  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,679,073 - 62,679,133EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18402 AgrOrtholog
COSMIC UBXN1 COSMIC
Ensembl Genes ENSG00000162191 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000294119 ENTREZGENE
  ENST00000294119.6 UniProtKB/Swiss-Prot
  ENST00000301935 ENTREZGENE
  ENST00000301935.10 UniProtKB/Swiss-Prot
  ENST00000529640.5 UniProtKB/TrEMBL
  ENST00000533000.5 UniProtKB/TrEMBL
  ENST00000534176 ENTREZGENE
  ENST00000534176.1 UniProtKB/TrEMBL
  ENST00000616865 ENTREZGENE
  ENST00000616865.4 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000162191 GTEx
HGNC ID HGNC:18402 ENTREZGENE
Human Proteome Map UBXN1 Human Proteome Map
InterPro UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA_UBXN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBX_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:51035 UniProtKB/Swiss-Prot
NCBI Gene 51035 ENTREZGENE
OMIM 616378 OMIM
PANTHER UBX DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
  UBX DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
  UBX DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  UBX DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162408336 PharmGKB
PROSITE UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WTZ5 ENTREZGENE, UniProtKB/TrEMBL
  B4E0P8 ENTREZGENE, UniProtKB/TrEMBL
  E9PJ81 ENTREZGENE, UniProtKB/TrEMBL
  E9PRQ7_HUMAN UniProtKB/TrEMBL
  E9PS08_HUMAN UniProtKB/TrEMBL
  Q04323 ENTREZGENE
  Q05BV2_HUMAN UniProtKB/TrEMBL
  Q9BV93 ENTREZGENE
  Q9BVV5 ENTREZGENE
  UBXN1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q9BV93 UniProtKB/Swiss-Prot
  Q9BVV5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 UBXN1  UBX domain protein 1  LOC51035  SAPK substrate protein 1  Symbol and/or name change 5135510 APPROVED