Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EFNA2 mRNA | CTD | PMID:36331819 | (S)-nicotine | increases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of EFNA2 mRNA | CTD | PMID:23825647 | 17beta-estradiol | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of EFNA2 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Efna2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EFNA2 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EFNA2 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Efna2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of EFNA2 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-palmitoylglycerol | increases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of EFNA2 mRNA | CTD | PMID:37199045 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of EFNA2 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of EFNA2 mRNA | CTD | PMID:31881176 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of EFNA2 mRNA | CTD | PMID:16483693 | arsenite(3-) | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | TRP53 protein affects the reaction [arsenite results in decreased expression of EFNA2 mRNA] | CTD | PMID:18929588 | arsenite(3-) | decreases expression | ISO | Efna2 (Mus musculus) | 6480464 | arsenite results in decreased expression of EFNA2 mRNA | CTD | PMID:18929588 | benzo[a]pyrene | affects methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of EFNA2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of EFNA2 exon | CTD | PMID:27901495 | benzo[e]pyrene | decreases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of EFNA2 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of EFNA2 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Efna2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of EFNA2 mRNA | CTD | PMID:32156529 | bisphenol F | multiple interactions | ISO | EFNA2 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of EFNA2 gene | CTD | PMID:31601247 | choline | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNA2 gene | CTD | PMID:20938992 | cisplatin | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of EFNA2 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | EFNA2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of EFNA2 mRNA | CTD | PMID:27392435 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of EFNA2 mRNA | CTD | PMID:15691709 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of EFNA2 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of EFNA2 mRNA | CTD | PMID:26033743 | cyclosporin A | decreases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of EFNA2 promoter | CTD | PMID:27989131 | decabromodiphenyl ether | affects expression | ISO | EFNA2 (Homo sapiens) | 6480464 | decabromobiphenyl ether affects the expression of EFNA2 mRNA | CTD | PMID:24834073 | diazinon | increases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of EFNA2 gene | CTD | PMID:22964155 | dibutyl phthalate | decreases expression | ISO | Efna2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of EFNA2 mRNA | CTD | PMID:17361019 and PMID:21266533 | dichloroacetic acid | increases expression | ISO | Efna2 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of EFNA2 mRNA | CTD | PMID:28962523 | dicrotophos | increases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of EFNA2 mRNA | CTD | PMID:28302478 | fluoranthene | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of EFNA2 mRNA | CTD | PMID:28329830 | folic acid | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNA2 gene | CTD | PMID:20938992 | fulvestrant | multiple interactions | ISO | EFNA2 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of EFNA2 gene | CTD | PMID:31601247 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of EFNA2 mRNA | CTD | PMID:27387713 | gentamycin | affects expression | EXP | | 6480464 | Gentamicins affects the expression of EFNA2 mRNA | CTD | PMID:33387578 | glyphosate | decreases methylation | EXP | | 6480464 | Glyphosate results in decreased methylation of EFNA2 gene | CTD | PMID:31011160 | hydrazine | decreases expression | ISO | Efna2 (Mus musculus) | 6480464 | hydrazine results in decreased expression of EFNA2 mRNA | CTD | PMID:15282401 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of EFNA2 mRNA | CTD | PMID:20080153 | L-methionine | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNA2 gene | CTD | PMID:20938992 | lead(0) | affects methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Lead affects the methylation of EFNA2 gene | CTD | PMID:24519525 | lipopolysaccharide | multiple interactions | ISO | EFNA2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | melphalan | increases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Melphalan results in increased expression of EFNA2 mRNA | CTD | PMID:22363485 | mercury dibromide | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of EFNA2 mRNA | CTD | PMID:26272509 | methapyrilene | decreases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of EFNA2 intron | CTD | PMID:30157460 | nicotine | increases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of EFNA2 mRNA | CTD | PMID:23825647 | paracetamol | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of EFNA2 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of EFNA2 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Efna2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EFNA2 mRNA | CTD | PMID:36331819 | phenylmercury acetate | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of EFNA2 mRNA | CTD | PMID:26272509 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of EFNA2 mRNA | CTD | PMID:33725128 and PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | EFNA2 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | sunitinib | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of EFNA2 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of EFNA2 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of EFNA2 mRNA | CTD | PMID:33387578 | triptonide | decreases expression | ISO | Efna2 (Mus musculus) | 6480464 | triptonide results in decreased expression of EFNA2 mRNA | CTD | PMID:33045310 | tris(2-butoxyethyl) phosphate | affects expression | ISO | EFNA2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of EFNA2 mRNA | CTD | PMID:29024780 | urethane | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of EFNA2 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | EFNA2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of EFNA2 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | EFNA2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of EFNA2 mRNA | CTD | PMID:23179753 more ... | |