Efna2 (ephrin A2) - Rat Genome Database

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Gene: Efna2 (ephrin A2) Chinchilla lanigera
Analyze
Symbol: Efna2
Name: ephrin A2
RGD ID: 8799804
Description: ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN axon guidance (ortholog); bone remodeling (ortholog); ephrin receptor signaling pathway (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); cyclic hematopoiesis (ortholog); FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ephrin-A2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,614,791 - 6,627,287 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,614,828 - 6,627,287 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Efna2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,614,791 - 6,627,287 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,614,828 - 6,627,287 (-)NCBIChiLan1.0ChiLan1.0
EFNA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,284,227 - 1,301,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,285,873 - 1,301,431 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,285,872 - 1,301,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,237,168 - 1,250,944 (+)NCBINCBI36Build 36hg18NCBI36
Build 34191,237,167 - 1,250,944NCBI
Celera191,220,457 - 1,234,238 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,070,235 - 1,076,114 (+)NCBIHuRef
CHM1_1191,286,249 - 1,301,508 (+)NCBICHM1_1
T2T-CHM13v2.0191,253,481 - 1,270,685 (+)NCBIT2T-CHM13v2.0
Efna2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,015,316 - 80,025,844 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,015,316 - 80,025,844 (+)EnsemblGRCm39 Ensembl
GRCm381080,179,482 - 80,190,010 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,179,482 - 80,190,010 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,642,227 - 79,652,755 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,582,611 - 79,592,774 (+)NCBIMGSCv36mm8
Celera1081,194,340 - 81,204,868 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Efna2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,167,091 - 10,177,719 (-)NCBIGRCr8
mRatBN7.279,515,635 - 9,528,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,516,429 - 9,527,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,399,367 - 12,410,023 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,274,704 - 14,285,362 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,135,824 - 12,146,446 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,382,636 - 12,393,266 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,382,636 - 12,393,266 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,552,532 - 12,563,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,028,432 - 11,039,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,030,443 - 11,030,724 (-)NCBI
Celera77,692,874 - 7,702,935 (-)NCBICelera
Cytogenetic Map7q11NCBI
EFNA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,629,433 - 5,644,680 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,866,226 - 4,882,529 (+)NCBINHGRI_mPanPan1
EFNA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha2057,304,872 - 57,317,195 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,243,472 - 58,257,099 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,243,472 - 58,257,443 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,299,140 - 57,312,931 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,780,042 - 57,792,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,980,959 - 57,995,187 (-)NCBIUU_Cfam_GSD_1.0
Efna2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,177,009 - 217,186,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588648,336 - 657,785 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588648,336 - 657,768 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFNA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,165,193 - 77,179,246 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,165,187 - 77,179,936 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,849,811 - 77,863,280 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFNA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,054,382 - 1,069,544 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,054,483 - 1,068,232 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660817,793,189 - 7,808,389 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efna2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,380,554 - 7,393,376 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,380,675 - 7,393,322 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000016041   ⟹   ENSCLAP00000015877
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,614,791 - 6,627,287 (-)Ensembl
RefSeq Acc Id: XM_013505059   ⟹   XP_013360513
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,614,828 - 6,627,287 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013360513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015877
  ENSCLAP00000015877.1
RefSeq Acc Id: XP_013360513   ⟸   XM_013505059
- UniProtKB: A0A8C2VHT5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000015877   ⟸   ENSCLAT00000016041
Protein Domains
Ephrin RBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010919 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016041 ENTREZGENE
  ENSCLAT00000016041.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.420 UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/TrEMBL
  Ephrin UniProtKB/TrEMBL
  Ephrin-A_Ecto UniProtKB/TrEMBL
  Ephrin_CS UniProtKB/TrEMBL
  Ephrin_RBD UniProtKB/TrEMBL
NCBI Gene LOC102007446 ENTREZGENE
PANTHER EPHRIN-A2 UniProtKB/TrEMBL
  PTHR11304 UniProtKB/TrEMBL
Pfam Ephrin UniProtKB/TrEMBL
PRINTS EPHRIN UniProtKB/TrEMBL
PROSITE EPHRIN_RBD_1 UniProtKB/TrEMBL
  EPHRIN_RBD_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF49503 UniProtKB/TrEMBL
UniProt A0A8C2VHT5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Efna2  ephrin A2    ephrin-A2  Symbol and/or name change 5135510 APPROVED
2015-08-25 Efna2  ephrin-A2  LOC102007446  ephrin-A2-like  Symbol and/or name change 5135510 APPROVED