Oaz1 (ornithine decarboxylase antizyme 1) - Rat Genome Database

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Gene: Oaz1 (ornithine decarboxylase antizyme 1) Rattus norvegicus
Analyze
Symbol: Oaz1
Name: ornithine decarboxylase antizyme 1
RGD ID: 3219
Description: Exhibits enzyme binding activity and ornithine decarboxylase inhibitor activity. Predicted to be involved in negative regulation of polyamine transmembrane transport; positive regulation of intracellular protein transport; and positive regulation of protein catabolic process. Predicted to localize to cytoplasm and nucleus. Orthologous to human OAZ1 (ornithine decarboxylase antizyme 1); PARTICIPATES IN polyamine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bexarotene; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Oaz; ODC-Az; ODCAC; Ornithine decarboxylase antizyme
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Oaz1-ps  
Allele / Splice: Oaz1-ps  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0711,752,127 - 11,754,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,919,843 - 11,922,300 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,394,495 - 10,396,952 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,394,494 - 10,396,952 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBICelera
RH 3.4 Map740.6RGD
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1572540   PMID:8166639   PMID:9445370   PMID:12477932   PMID:12941943   PMID:15277517   PMID:16120325   PMID:16128579   PMID:16916800   PMID:17900240   PMID:18508777   PMID:19349429  
PMID:19449338   PMID:21861313   PMID:24967154  


Genomics

Comparative Map Data
Oaz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0711,752,127 - 11,754,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,919,843 - 11,922,300 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,394,495 - 10,396,952 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,394,494 - 10,396,952 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBICelera
RH 3.4 Map740.6RGD
Cytogenetic Map7q11NCBI
OAZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl192,269,509 - 2,273,490 (+)EnsemblGRCh38hg38GRCh38
GRCh38192,269,486 - 2,273,488 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37192,269,485 - 2,273,487 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,220,520 - 2,224,487 (+)NCBINCBI36hg18NCBI36
Build 34192,220,519 - 2,224,487NCBI
Celera192,203,699 - 2,207,665 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef192,040,604 - 2,044,469 (+)NCBIHuRef
CHM1_1192,269,085 - 2,273,087 (+)NCBICHM1_1
Oaz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,662,490 - 80,665,124 (+)NCBIGRCm39mm39
GRCm39 Ensembl1080,662,490 - 80,665,124 (+)Ensembl
GRCm381080,826,656 - 80,829,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,826,656 - 80,829,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,289,401 - 80,292,035 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,229,785 - 80,232,414 (+)NCBImm8
Celera1081,845,454 - 81,848,088 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Oaz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,871,418 - 5,874,200 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,871,418 - 5,874,200 (-)NCBIChiLan1.0ChiLan1.0
OAZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1192,250,599 - 2,254,534 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl192,250,678 - 2,254,179 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0191,279,139 - 1,283,079 (+)NCBIMhudiblu_PPA_v0panPan3
OAZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,769,317 - 56,770,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,769,319 - 56,770,930 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2056,564,657 - 56,567,316 (-)NCBI
ROS_Cfam_1.02057,502,449 - 57,505,111 (-)NCBI
UMICH_Zoey_3.12056,554,504 - 56,557,154 (-)NCBI
UNSW_CanFamBas_1.02057,039,687 - 57,042,333 (-)NCBI
UU_Cfam_GSD_1.02057,240,093 - 57,242,753 (-)NCBI
Oaz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,473,746 - 216,478,014 (-)NCBI
SpeTri2.0NW_0049365881,356,769 - 1,361,037 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OAZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,293,147 - 76,296,659 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,293,142 - 76,296,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2276,854,941 - 76,858,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OAZ1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,061,774 - 2,065,595 (+)NCBI
ChlSab1.1 Ensembl62,061,811 - 2,065,265 (+)Ensembl
Vero_WHO_p1.0NW_0236660816,645,566 - 6,649,397 (-)NCBI
Oaz1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248286,617,342 - 6,620,466 (-)NCBI

Position Markers
RH127959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,883,906 - 8,884,088 (+)MAPPER
mRatBN7.21137,084,624 - 37,084,806 (+)MAPPER
Rnor_6.01138,214,154 - 38,214,335NCBIRnor6.0
Rnor_6.0711,752,179 - 11,752,360NCBIRnor6.0
Rnor_5.01141,724,203 - 41,724,384UniSTSRnor5.0
Rnor_5.0711,919,894 - 11,920,075UniSTSRnor5.0
RGSC_v3.41137,729,459 - 37,729,640UniSTSRGSC3.4
RGSC_v3.4710,394,546 - 10,394,727UniSTSRGSC3.4
Celera77,068,029 - 7,068,210UniSTS
Celera1136,969,245 - 36,969,426UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map11q12UniSTS
RH142210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,885,265 - 8,885,434 (+)MAPPER
Rnor_6.0711,753,538 - 11,753,706NCBIRnor6.0
Rnor_5.0711,921,253 - 11,921,421UniSTSRnor5.0
RGSC_v3.4710,395,905 - 10,396,073UniSTSRGSC3.4
Celera77,069,388 - 7,069,556UniSTS
RH 3.4 Map740.6UniSTS
Cytogenetic Map7q11UniSTS
Oaz1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,084,727 - 37,084,884 (+)MAPPER
mRatBN7.278,884,009 - 8,884,166 (+)MAPPER
Rnor_6.0711,752,282 - 11,752,438NCBIRnor6.0
Rnor_6.01138,214,257 - 38,214,413NCBIRnor6.0
Rnor_5.01141,724,306 - 41,724,462UniSTSRnor5.0
Rnor_5.0711,919,997 - 11,920,153UniSTSRnor5.0
RGSC_v3.41137,729,562 - 37,729,718UniSTSRGSC3.4
RGSC_v3.4710,394,649 - 10,394,805UniSTSRGSC3.4
Celera77,068,132 - 7,068,288UniSTS
Celera1136,969,348 - 36,969,504UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map11q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7134147172Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7134828535Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7134828535Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7137009673Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7138119654Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7265313832258115Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)72920071124838025Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7591147750911477Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7595196950951969Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7975804554758045Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)71164710256647102Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:159
Interacting mature miRNAs:177
Transcripts:ENSRNOT00000026341
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 4 1 4 1
Medium 3 39 57 41 19 41 8 10 70 35 40 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001297557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC158783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D11372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000026341   ⟹   ENSRNOP00000026341
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl711,752,412 - 11,754,508 (-)Ensembl
RefSeq Acc Id: NM_001297557   ⟹   NP_001284486
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001301048   ⟹   NP_001287977
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139081   ⟹   NP_620781
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.278,883,855 - 8,886,315 (-)NCBI
Rnor_6.0711,752,127 - 11,754,587 (-)NCBI
Rnor_5.0711,919,843 - 11,922,300 (-)NCBI
RGSC_v3.4710,394,495 - 10,396,952 (-)RGD
Celera77,067,977 - 7,070,437 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_620781   ⟸   NM_139081
- Peptide Label: isoform 1
- UniProtKB: P54370 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001287977   ⟸   NM_001301048
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001284486   ⟸   NM_001297557
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSRNOP00000026341   ⟸   ENSRNOT00000026341

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695016
Promoter ID:EPDNEW_R5526
Type:single initiation site
Name:Oaz1_1
Description:ornithine decarboxylase antizyme 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,754,582 - 11,754,642EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3219 AgrOrtholog
Ensembl Genes ENSRNOG00000019459 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000026341 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026341 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ODC-AZ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ODC_AZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ODC_AZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25502 UniProtKB/Swiss-Prot
NCBI Gene 25502 ENTREZGENE
PANTHER PTHR10279 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10279:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ODC_AZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Oaz1 PhenoGen
PROSITE ODC_AZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F1M8D8_RAT UniProtKB/TrEMBL
  OAZ1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27     Oaz1  ornithine decarboxylase antizyme 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Oaz1  ornithine decarboxylase antizyme 1  Oaz  Ornithine decarboxylase antizyme  Symbol and Name updated 625702 APPROVED
2002-06-10 Oaz  Ornithine decarboxylase antizyme      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation degradation involves functional ubiquitin-dependent proteolytic activity 727347