Gene: Eef2 (eukaryotic translation elongation factor 2) Rattus norvegicus
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Symbol:
Eef2
Name:
eukaryotic translation elongation factor 2
RGD ID:
61979
Description:
Exhibits several functions, including 5S rRNA binding activity; actin filament binding activity; and p53 binding activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; positive regulation of cytoplasmic translation; and response to ischemia. Localizes to cytosol; membrane raft; and polysomal ribosome. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2); PARTICIPATES IN mTOR signaling pathway; translation elongation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
Ef-2; elongation factor 2; elongation factor-2
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
EEF2 (eukaryotic translation elongation factor 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Eef2 (eukaryotic translation elongation factor 2) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Eef2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
EEF2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
EEF2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Eef2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
EEF2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
EEF2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Eef2 (eukaryotic translation elongation factor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
EFTUD2 (elongation factor Tu GTP binding domain containing 2) HGNC
OrthoMCL
Alliance orthologs 3
Mus musculus (house mouse):
Eef2 (eukaryotic translation elongation factor 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Homo sapiens (human):
EEF2 (eukaryotic translation elongation factor 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
eef2a.1 (eukaryotic translation elongation factor 2a, tandem duplicate 1)
Alliance
DIOPT (OMA|OrthoFinder|PANTHER|TreeFam)
Danio rerio (zebrafish):
eef2b (eukaryotic translation elongation factor 2b)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
eef2l2 (eukaryotic translation elongation factor 2, like 2)
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
EFT1
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
eEF2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
eef-2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
EFT2
Alliance
DIOPT (Ensembl Compara|OMA|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 7 11,401,501 - 11,406,771 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 11,401,501 - 11,406,771 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 7 11,568,907 - 11,574,177 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 10,017,061 - 10,022,331 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 7 10,017,060 - 10,022,331 (-) NCBI Celera 7 6,721,131 - 6,726,401 (-) NCBI Celera Cytogenetic Map 7 q11 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
amenorrhea ISO RGD:1343628 8554872 ClinVar Annotator: match by term: Primary amenorrhea ClinVar PMID:21681106 spinocerebellar ataxia type 26 ISO RGD:1343628 8554872 ClinVar Annotator: match by OMIM:609306 ClinVar PMID:15732118 , PMID:23001565
Imported Annotations - CTD
adenocarcinoma ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21554491 Breast Neoplasms ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:20562527 Lung Neoplasms ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21554491 Neoplasm Invasiveness ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21554491 Neoplasm Metastasis ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:20562527 osteoarthritis ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:18784066 Recurrence ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21554491 renal cell carcinoma ISO RGD:1343628 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15108329 Imported Annotations - OMIM
spinocerebellar ataxia type 26 ISO RGD:1343628 7240710 OMIM
(S)-amphetamine decreases expression ISO RGD:62271 6480464 Dextroamphetamine results in decreased expression of EEF2 mRNA CTD PMID:12558987 (S)-nicotine multiple interactions ISO RGD:1343628 6480464 [Nicotine results in increased expression of UBA2 protein] which results in increased sumoylation of EEF2 protein CTD PMID:21554491 (S)-nicotine increases expression ISO RGD:1343628 6480464 Nicotine results in increased expression of EEF2 protein modified form CTD PMID:21554491 (Z)-3-butylidenephthalide increases expression ISO RGD:1343628 6480464 butylidenephthalide results in increased expression of EEF2 protein CTD PMID:23770345 1,2,4-trimethylbenzene decreases expression EXP 6480464 pseudocumene results in decreased expression of EEF2 protein CTD PMID:17337753 1,2-dimethylhydrazine increases expression ISO RGD:62271 6480464 1, 2-Dimethylhydrazine results in increased expression of EEF2 mRNA CTD PMID:22206623 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:62271 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:62271 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 17alpha-ethynylestradiol multiple interactions ISO RGD:62271 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EEF2 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:62271 6480464 Ethinyl Estradiol results in increased expression of EEF2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of EEF2 mRNA CTD PMID:26496021 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:1343628 6480464 Metribolone promotes the reaction [NDRG1 protein binds to EEF2 protein] CTD PMID:17220478 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:1343628 6480464 Metribolone results in increased expression of EEF2 protein CTD PMID:17152098 2,2',4,4',5,5'-hexachlorobiphenyl affects expression ISO RGD:62271 6480464 2 more ... CTD PMID:24680724 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:62271 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EEF2 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:62271 6480464 Tetrachlorodibenzodioxin results in increased expression of EEF2 mRNA CTD PMID:32553695 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:62271 6480464 Tetrachlorodibenzodioxin affects the expression of EEF2 mRNA CTD PMID:21570461 , PMID:24680724 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EEF2 protein CTD PMID:16548065 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:62271 6480464 2 more ... CTD PMID:18550172 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:19954255 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of EEF2 mRNA CTD PMID:15890375 3,4-methylenedioxymethamphetamine increases expression ISO RGD:62271 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of EEF2 mRNA CTD PMID:20188158 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO RGD:62271 6480464 3 more ... CTD PMID:20512997 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of EEF2 protein CTD PMID:26597043 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of EEF2 protein CTD PMID:26072098 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of EEF2 mRNA more ... CTD PMID:28628672 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of EEF2 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of EEF2 mRNA CTD PMID:28628672 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EEF2 mRNA CTD PMID:15890375 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of EEF2 protein CTD PMID:16469450 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of EEF2 mRNA CTD PMID:18077114 7,12-dimethyltetraphene affects expression ISO RGD:62271 6480464 9 more ... CTD PMID:21785161 acetaldehyde decreases expression EXP 6480464 Acetaldehyde results in decreased expression of EEF2 protein CTD PMID:16469450 acrylamide increases expression ISO RGD:62271 6480464 Acrylamide results in increased expression of EEF2 mRNA CTD PMID:30807115 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of EEF2 mRNA CTD PMID:15890375 aflatoxin B1 decreases methylation ISO RGD:1343628 6480464 Aflatoxin B1 results in decreased methylation of EEF2 gene CTD PMID:27153756 aldehydo-D-glucose decreases phosphorylation ISO RGD:62271 6480464 Glucose results in decreased phosphorylation of EEF2 protein CTD PMID:19765649 aldehydo-D-glucose multiple interactions ISO RGD:62271 6480464 resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] CTD PMID:19765649 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EEF2 mRNA CTD PMID:16483693 aniline increases nitrosation EXP 6480464 aniline results in increased nitrosation of EEF2 protein CTD PMID:21708182 arsenous acid decreases expression ISO RGD:1343628 6480464 Arsenic Trioxide results in decreased expression of EEF2 protein CTD PMID:19364129 benzene affects expression EXP 6480464 Benzene affects the expression of EEF2 mRNA CTD PMID:15878777 benzo[a]pyrene increases expression ISO RGD:1343628 6480464 Benzo(a)pyrene results in increased expression of EEF2 protein CTD PMID:25628927 benzo[a]pyrene increases expression ISO RGD:62271 6480464 Benzo(a)pyrene metabolite results in increased expression of EEF2 mRNA CTD PMID:32553695 benzo[a]pyrene multiple interactions ISO RGD:1343628 6480464 PARG affects the reaction [Benzo(a)pyrene results in increased expression of EEF2 protein] CTD PMID:25628927 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EEF2 promoter CTD PMID:23359474 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EEF2 promoter, [bisphenol A co-treated with Estradiol] results in decreased expression of EEF2 mRNA CTD PMID:23359474 , PMID:26496021 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EEF2 mRNA CTD PMID:30903817 bisphenol A affects expression ISO RGD:1343628 6480464 bisphenol A affects the expression of EEF2 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of EEF2 mRNA CTD PMID:28628672 bisphenol A increases expression ISO RGD:62271 6480464 bisphenol A results in increased expression of EEF2 protein CTD PMID:24909818 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EEF2 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol F multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EEF2 mRNA CTD PMID:28628672 Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of EEF2 protein CTD PMID:28903499 caffeine multiple interactions ISO RGD:62271 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 calcitriol multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 calcium atom multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 calcium(0) multiple interactions EXP 6480464 [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of EEF2 protein] CTD PMID:20359164 carbon nanotube affects expression ISO RGD:62271 6480464 Nanotubes, Carbon affects the expression of EEF2 protein CTD PMID:21135415 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of EEF2 mRNA CTD PMID:18172885 chlorohydrocarbon decreases expression EXP 6480464 Hydrocarbons, Chlorinated results in decreased expression of EEF2 mRNA CTD PMID:18077114 chloropicrin decreases expression ISO RGD:1343628 6480464 chloropicrin results in decreased expression of EEF2 mRNA CTD PMID:26352163 ciguatoxin CTX1B affects expression ISO RGD:62271 6480464 Ciguatoxins affects the expression of EEF2 mRNA CTD PMID:18353800 cisplatin decreases response to substance ISO RGD:1343628 6480464 EEF2 protein modified form results in decreased susceptibility to Cisplatin CTD PMID:21554491 clobetasol increases expression ISO RGD:62271 6480464 Clobetasol results in increased expression of EEF2 mRNA CTD PMID:27462272 clofibrate multiple interactions ISO RGD:62271 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of EEF2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of EEF2 mRNA] CTD PMID:17585979 clofibrate decreases expression ISO RGD:62271 6480464 Clofibrate results in decreased expression of EEF2 mRNA CTD PMID:17585979 cumene hydroperoxide decreases expression EXP 6480464 cumene hydroperoxide results in decreased expression of EEF2, cumene hydroperoxide results in decreased expression of EEF2 protein CTD PMID:16469450 more ... cumene hydroperoxide multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:17510559 cyclophosphamide decreases expression EXP 6480464 Cyclophosphamide results in decreased expression of EEF2 mRNA CTD PMID:18246545 cyclosporin A decreases expression ISO RGD:1343628 6480464 Cyclosporine results in decreased expression of EEF2 mRNA CTD PMID:21163907 cyclosporin A increases expression ISO RGD:1343628 6480464 Cyclosporine results in increased expression of EEF2 mRNA CTD PMID:20106945 cytarabine decreases expression ISO RGD:1343628 6480464 Cytarabine results in decreased expression of EEF2 mRNA CTD PMID:21198554 D-glucose decreases phosphorylation ISO RGD:62271 6480464 Glucose results in decreased phosphorylation of EEF2 protein CTD PMID:19765649 D-glucose multiple interactions ISO RGD:62271 6480464 resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] CTD PMID:19765649 decabromodiphenyl ether decreases expression ISO RGD:62271 6480464 decabromobiphenyl ether results in decreased expression of EEF2 mRNA CTD PMID:29699156 dexamethasone multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of EEF2 mRNA more ... CTD PMID:28628672 diarsenic trioxide decreases expression ISO RGD:1343628 6480464 Arsenic Trioxide results in decreased expression of EEF2 protein CTD PMID:19364129 dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of EEF2 promoter CTD PMID:23359474 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA CTD PMID:18636392 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EEF2 mRNA CTD PMID:15890375 disodium selenite increases expression ISO RGD:1343628 6480464 Sodium Selenite results in increased expression of EEF2 mRNA CTD PMID:18175754 doxorubicin increases expression ISO RGD:1343628 6480464 Doxorubicin results in increased expression of EEF2 mRNA CTD PMID:29803840 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of EEF2 mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO RGD:1343628 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of EEF2 protein CTD PMID:23301498 ethanol affects splicing ISO RGD:62271 6480464 Ethanol affects the splicing of EEF2 mRNA CTD PMID:30319688 fluoxetine increases phosphorylation EXP 6480464 Fluoxetine results in increased phosphorylation of EEF2 protein CTD PMID:16817885 genistein decreases expression ISO RGD:1343628 6480464 Genistein results in decreased expression of EEF2 mRNA CTD PMID:16705744 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of EEF2 protein CTD PMID:22061828 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of EEF2 mRNA CTD PMID:22061828 glucose decreases phosphorylation ISO RGD:62271 6480464 Glucose results in decreased phosphorylation of EEF2 protein CTD PMID:19765649 glucose multiple interactions ISO RGD:62271 6480464 resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] CTD PMID:19765649 gold atom decreases expression ISO RGD:62271 6480464 Gold analog results in decreased expression of EEF2 protein CTD PMID:24780912 gold(0) decreases expression ISO RGD:62271 6480464 Gold analog results in decreased expression of EEF2 protein CTD PMID:24780912 hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF2 protein] CTD PMID:23178681 hyaluronic acid decreases expression EXP 6480464 Hyaluronic Acid analog results in decreased expression of EEF2 protein CTD PMID:23178681 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of EEF2 protein CTD PMID:23178681 hydrogen peroxide multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of EEF2 protein] CTD PMID:23178681 indometacin multiple interactions ISO RGD:1343628 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of EEF2 mRNA more ... CTD PMID:28628672 lovastatin decreases expression ISO RGD:62271 6480464 Lovastatin results in decreased expression of EEF2 mRNA CTD PMID:20493250 malonaldehyde decreases expression EXP 6480464 Malondialdehyde results in decreased expression of EEF2 protein CTD PMID:16469450 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of EEF2 mRNA CTD PMID:15890375 methylparaben increases expression ISO RGD:1343628 6480464 methylparaben results in increased expression of EEF2 mRNA CTD PMID:31745603 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of EEF2 mRNA CTD PMID:15890375 N-nitrosomorpholine affects expression EXP 6480464 N-nitrosomorpholine affects the expression of EEF2 protein CTD PMID:19716841 naphthalene decreases expression ISO RGD:62271 6480464 naphthalene results in decreased expression of EEF2 protein CTD PMID:19438287 naphthalene multiple interactions ISO RGD:62271 6480464 [naphthalene co-treated with CFTR gene mutant form] results in decreased expression of EEF2 protein CTD PMID:19438287 nickel dichloride increases expression ISO RGD:62271 6480464 nickel chloride results in increased expression of EEF2 mRNA CTD PMID:12729255 nickel subsulfide affects expression ISO RGD:62271 6480464 nickel subsulfide affects the expression of EEF2 mRNA CTD PMID:12729255 nicotine multiple interactions ISO RGD:1343628 6480464 [Nicotine results in increased expression of UBA2 protein] which results in increased sumoylation of EEF2 protein CTD PMID:21554491 nicotine increases expression ISO RGD:1343628 6480464 Nicotine results in increased expression of EEF2 protein modified form CTD PMID:21554491 ochratoxin A increases expression ISO RGD:1343628 6480464 ochratoxin A results in increased expression of EEF2 protein CTD PMID:26861962 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA CTD PMID:18636392 paclitaxel decreases expression ISO RGD:1343628 6480464 Paclitaxel results in decreased expression of EEF2 mRNA CTD PMID:15000894 paracetamol multiple interactions ISO RGD:62271 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of EEF2 mRNA more ... CTD PMID:17585979 , PMID:25499718 paracetamol affects expression ISO RGD:62271 6480464 Acetaminophen affects the expression of EEF2 mRNA CTD PMID:17562736 perfluorooctanoic acid decreases expression ISO RGD:1343628 6480464 perfluorooctanoic acid results in decreased expression of EEF2 protein CTD PMID:22609092 phenethyl isothiocyanate decreases expression EXP 6480464 phenethyl isothiocyanate results in decreased expression of EEF2 mRNA CTD PMID:17616710 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of EEF2 mRNA CTD PMID:15890375 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of EEF2 mRNA CTD PMID:15890375 prostaglandin A1 increases metabolic processing ISO RGD:62271 6480464 prostaglandin A1 analog results in increased metabolism of EEF2 protein CTD PMID:19800325 protein kinase inhibitor decreases phosphorylation ISO RGD:62271 6480464 Protein Kinase Inhibitors results in decreased phosphorylation of EEF2 protein CTD PMID:25330770 protein kinase inhibitor decreases phosphorylation ISO RGD:1343628 6480464 Protein Kinase Inhibitors results in decreased phosphorylation of EEF2 protein CTD PMID:25330770 pyrogallol decreases expression ISO RGD:62271 6480464 Pyrogallol results in decreased expression of EEF2 mRNA CTD PMID:20362636 pyrogallol multiple interactions ISO RGD:62271 6480464 Silymarin inhibits the reaction [Pyrogallol results in decreased expression of EEF2 mRNA] CTD PMID:20362636 quinoline decreases expression ISO RGD:1343628 6480464 quinoline analog results in decreased expression of EEF2 protein CTD PMID:18645022 resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of EEF2 protein CTD PMID:18562309 resveratrol multiple interactions EXP 6480464 resveratrol results in increased phosphorylation of and results in decreased activity of EEF2 protein CTD PMID:25394677 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of EEF2 mRNA CTD PMID:25394677 resveratrol increases phosphorylation ISO RGD:1343628 6480464 resveratrol results in increased phosphorylation of EEF2 protein CTD PMID:22349766 resveratrol decreases expression ISO RGD:1343628 6480464 resveratrol results in decreased expression of EEF2 protein CTD PMID:22349766 resveratrol multiple interactions ISO RGD:62271 6480464 resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] CTD PMID:19765649 rotenone increases oxidation EXP 6480464 Rotenone results in increased oxidation of EEF2 protein CTD PMID:30951809 rottlerin decreases phosphorylation EXP 6480464 rottlerin results in decreased phosphorylation of EEF2 protein CTD PMID:12720544 silicon dioxide affects secretion ISO RGD:1343628 6480464 Silicon Dioxide analog affects the secretion of EEF2 protein CTD PMID:25895662 sirolimus increases phosphorylation ISO RGD:1343628 6480464 Sirolimus results in increased phosphorylation of EEF2 protein CTD PMID:25940091 sodium arsenite decreases expression ISO RGD:1343628 6480464 sodium arsenite results in decreased expression of EEF2 protein CTD PMID:20050688 sodium arsenite increases expression ISO RGD:62271 6480464 sodium arsenite results in increased expression of EEF2 protein CTD PMID:29044176 sodium fluoride increases expression ISO RGD:62271 6480464 Sodium Fluoride results in increased expression of EEF2 mRNA, Sodium Fluoride results in increased expression of EEF2 protein CTD PMID:27548804 , PMID:27862939 sunitinib increases expression ISO RGD:1343628 6480464 Sunitinib results in increased expression of EEF2 mRNA CTD PMID:31533062 T-2 Toxin affects expression EXP 6480464 T-2 Toxin affects the expression of EEF2 protein CTD PMID:26141394 tanespimycin increases expression ISO RGD:1343628 6480464 tanespimycin analog results in increased expression of EEF2 protein, tanespimycin results in increased expression of EEF2 protein CTD PMID:31370342 tanespimycin multiple interactions ISO RGD:1343628 6480464 [tanespimycin co-treated with VER 155008] results in increased expression of EEF2 protein CTD PMID:31370342 tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of EEF2 protein CTD PMID:16469450 tetrachloroethene increases expression ISO RGD:62271 6480464 Tetrachloroethylene results in increased expression of EEF2 mRNA CTD PMID:28973375 titanium dioxide decreases expression ISO RGD:62271 6480464 titanium dioxide results in decreased expression of EEF2 mRNA CTD PMID:23557971 titanium dioxide increases expression ISO RGD:62271 6480464 titanium dioxide results in increased expression of EEF2 mRNA CTD PMID:29264374 torin 1 increases phosphorylation ISO RGD:1343628 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1, 6)naphthyridin-2(1H)-one results in increased phosphorylation of EEF2 protein CTD PMID:25940091 tremolite asbestos decreases expression ISO RGD:62271 6480464 tremolite results in decreased expression of EEF2 mRNA CTD PMID:29279043 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of EEF2 mRNA CTD PMID:19448997 trichloroethene increases expression ISO RGD:62271 6480464 Trichloroethylene results in increased expression of EEF2 mRNA CTD PMID:28973375 trimellitic anhydride increases expression ISO RGD:62271 6480464 trimellitic anhydride results in increased expression of EEF2 mRNA CTD PMID:19042947 urethane increases expression ISO RGD:1343628 6480464 Urethane results in increased expression of EEF2 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:1343628 6480464 Valproic Acid results in increased methylation of EEF2 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1343628 6480464 Valproic Acid affects the expression of EEF2 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of EEF2 mRNA CTD PMID:23034163 vitamin E multiple interactions EXP 6480464 Vitamin E analog inhibits the reaction [cumene hydroperoxide results in decreased expression of EEF2 protein] CTD PMID:17510559 vitamin E increases expression EXP 6480464 Vitamin E analog results in increased expression of EEF2 protein CTD PMID:17510559 warfarin decreases expression ISO RGD:62271 6480464 Warfarin results in decreased expression of EEF2 mRNA CTD PMID:20493250
Gene-Chemical Interaction Annotations
