Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Eef2 (eukaryotic translation elongation factor 2) Rattus norvegicus
Analyze
Symbol: Eef2
Name: eukaryotic translation elongation factor 2
Description: Exhibits several functions, including 5S rRNA binding activity; actin filament binding activity; and p53 binding activity. Involved in several processes, including aging; cellular response to brain-derived neurotrophic factor stimulus; and response to ischemia. Localizes to the cytosol; membrane raft; and polysomal ribosome. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2); PARTICIPATES IN mTOR signaling pathway; translation elongation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ef-2; elongation factor 2; elongation factor-2
Orthologs:
Homo sapiens (human) : EEF2 (eukaryotic translation elongation factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Eef2 (eukaryotic translation elongation factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eef2 (eukaryotic translation elongation factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EEF2 (eukaryotic translation elongation factor 2)
Canis lupus familiaris (dog) : EEF2 (eukaryotic translation elongation factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eef2 (eukaryotic translation elongation factor 2)
Sus scrofa (pig) : EEF2 (eukaryotic translation elongation factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0711,401,501 - 11,406,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0711,568,907 - 11,574,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,017,061 - 10,022,331 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,017,060 - 10,022,331 (-)NCBI
Celera76,721,131 - 6,726,401 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Eef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61979
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.