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Gene: Kitlg (KIT ligand) Rattus norvegicus
Symbol: Kitlg
Name: KIT ligand
Description: Predicted to have cytokine activity and stem cell factor receptor binding activity. Involved in ovarian follicle development and positive regulation of cell population proliferation. Predicted to localize to several cellular components, including extracellular space; filopodium; and lamellipodium. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69 and familial progressive hyperpigmentation with or without hypopigmentation. Orthologous to human KITLG (KIT ligand); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-kit ligand; hematopoietic growth factor KL; Kitl; Kl1; Kl2; LOC60427; LOC60428; mast cell growth factor; Mgf; SCF; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor KL-1 precursor; stem cell factor KL-2 precursor
Homo sapiens (human) : KITLG (KIT ligand)  HGNC  Alliance
Mus musculus (house mouse) : Kitl (kit ligand)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kitlg (KIT ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : KITLG (KIT ligand)
Canis lupus familiaris (dog) : KITLG (KIT ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kitlg (KIT ligand)
Sus scrofa (pig) : KITLG (KIT ligand)
Chlorocebus sabaeus (African green monkey) : KITLG (KIT ligand)
Heterocephalus glaber (naked mole-rat) : Kitlg (KIT ligand)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0742,269,784 - 42,351,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl742,269,784 - 42,351,054 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0742,302,651 - 42,383,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4737,714,157 - 37,795,722 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1737,734,427 - 37,804,538 (+)NCBI
Celera731,898,840 - 31,979,932 (+)NCBICelera
Cytogenetic Map7q21NCBI
RH 3.4 Map7286.2RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kitlg
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3086
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.