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Gene: Kitlg (KIT ligand) Rattus norvegicus
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Symbol: Kitlg
Name: KIT ligand
Description: Predicted to have cytokine activity and stem cell factor receptor binding activity. Involved in ovarian follicle development and positive regulation of cell population proliferation. Predicted to localize to several cellular components, including the extracellular space; filopodium; and lamellipodium. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69. Orthologous to human KITLG (KIT ligand); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-kit ligand; hematopoietic growth factor KL; Kitl; Kl1; Kl2; LOC60427; LOC60428; mast cell growth factor; Mgf; SCF; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor KL-1 precursor; stem cell factor KL-2 precursor
Orthologs:
Homo sapiens (human) : KITLG (KIT ligand)  HGNC  Alliance
Mus musculus (house mouse) : Kitl (kit ligand)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kitlg (KIT ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : KITLG (KIT ligand)
Canis lupus familiaris (dog) : KITLG (KIT ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kitlg (KIT ligand)
Sus scrofa (pig) : KITLG (KIT ligand)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0742,269,784 - 42,351,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0742,302,651 - 42,383,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4737,714,157 - 37,795,722 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1737,734,427 - 37,804,538 (+)NCBI
Celera731,898,840 - 31,979,932 (+)NCBICelera
Cytogenetic Map7q21NCBI
RH 3.4 Map7286.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kitlg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3086
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.