Gene: Hcn2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2) Rattus norvegicus
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Symbol: Hcn2
Name: hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
Description: ENCODES a protein that exhibits molecular adaptor activity; PDZ domain binding; protein-containing complex binding; INVOLVED IN aging; brain development; cellular response to aldosterone; ASSOCIATED WITH Chronic Cerebral Hypoperfusion; Dental Pulp Exposure; dermatitis; FOUND IN axon; cytoplasm; dendrite membrane; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene
AGR Description: Exhibits PDZ domain binding activity; involved in several processes, including aging, brain development, and cellular response to aldosterone; localizes to several cellular components, including the cytoplasm, neuron projection, and neuronal cell body; biomarker of dermatitis, meningitis, and visual epilepsy; orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2).
Merged Description: Exhibits PDZ domain binding activity; involved in several processes, including aging, brain development, and cellular response to aldosterone; localizes to several cellular components, including the cytoplasm, neuron projection, and neuronal cell body; biomarker of dermatitis, meningitis, and visual epilepsy; orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hyperpolarization activated cyclic nucleotide-gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0712,851,730 - 12,870,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0713,021,934 - 13,051,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,485,257 - 11,503,614 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,485,256 - 11,503,614 (-)NCBI
Celera78,143,888 - 8,161,946 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hcn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620689
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.