Nudt4 (nudix hydrolase 4) - Rat Genome Database

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Gene: Nudt4 (nudix hydrolase 4) Rattus norvegicus
Analyze
Symbol: Nudt4
Name: nudix hydrolase 4
RGD ID: 621355
Description: Predicted to enable pyrophosphatase activity and snoRNA binding activity. Predicted to be involved in diphosphoinositol polyphosphate metabolic process and nucleotide catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Orthologous to human NUDT4 (nudix hydrolase 4); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; diphosphoinositol polyphosphate phosphohydolase type II; diphosphoinositol polyphosphate phosphohydrolase 2; DIPP-2; DRCF-5; LOC360416; nucleoside diphosphate-linked moiety X motif 4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; nudix motif 4; nudix-type motif 4; rDIPP2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8732,074,978 - 32,091,491 (-)NCBIGRCr8
mRatBN7.2730,188,100 - 30,204,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,188,100 - 30,204,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,174,576 - 32,191,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,348,209 - 34,364,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0734,123,196 - 34,139,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,643,916 - 36,660,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,695,609 - 36,712,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,753,728 - 32,769,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,773,998 - 32,790,224NCBI
Celera727,261,241 - 27,277,464 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 130 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nudt4Rat(-)-epigallocatechin 3-gallate multiple interactionsISONUDT4 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NUDT4 mRNACTDPMID:22079256
Nudt4Rat(1->4)-beta-D-glucan multiple interactionsISONudt4 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NUDT4 mRNACTDPMID:36331819
Nudt4Rat(S)-nicotine increases expressionISONudt4 (Mus musculus)6480464Nicotine results in increased expression of NUDT4 mRNACTDPMID:17997037
Nudt4Rat1,2-dimethylhydrazine decreases expressionISONudt4 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of NUDT4 mRNACTDPMID:22206623
Nudt4Rat17alpha-ethynylestradiol increases expressionISONudt4 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of NUDT4 mRNACTDPMID:17942748
Nudt4Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of NUDT4 mRNACTDPMID:12075121
Nudt4Rat17alpha-ethynylestradiol multiple interactionsISONudt4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT4 mRNACTDPMID:17942748
Nudt4Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of NUDT4 mRNACTDPMID:32145629
Nudt4Rat17beta-estradiol increases expressionISONudt4 (Mus musculus)6480464Estradiol results in increased expression of NUDT4 mRNACTDPMID:39298647
Nudt4Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISONudt4 (Mus musculus)64804642 more ...CTDPMID:31388691
Nudt4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONudt4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT4 mRNACTDPMID:17942748
Nudt4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NUDT4 mRNACTDPMID:34747641
Nudt4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NUDT4 mRNACTDPMID:16960034 more ...
Nudt4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONudt4 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NUDT4 mRNACTDPMID:21570461
Nudt4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of NUDT4 mRNACTDPMID:22298810
Nudt4Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISONudt4 (Mus musculus)64804642 more ...CTDPMID:38648751
Nudt4Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of NUDT4 mRNACTDPMID:21346803
Nudt4Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISONUDT4 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NUDT4 mRNA more ...CTDPMID:28628672
Nudt4Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of NUDT4 mRNACTDPMID:19162173
Nudt4Rat4,4'-sulfonyldiphenol multiple interactionsISONUDT4 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of NUDT4 mRNACTDPMID:28628672

1 to 20 of 130 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nudt4Ratadenosine 5'-(hexahydrogen pentaphosphate) catabolic process involved_inIBAPANTHER:PTN000290327 and PomBase:SPAC13G6.141600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratdiadenosine hexaphosphate catabolic process involved_inIBAPANTHER:PTN000290327 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratdiadenosine pentaphosphate catabolic process involved_inIBAPANTHER:PTN000290327 and PomBase:SPAC13G6.141600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratdiphosphoinositol polyphosphate metabolic process involved_inIBAPANTHER:PTN000290327 and UniProtKB:O959891600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratphosphatidylinositol metabolic process  NAS 633460 RGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nudt4Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Nudt4Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Nudt4Ratcytoplasm is_active_inIBAFB:FBgn0036111 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratcytosol located_inISONUDT4 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Nudt4Ratnucleus is_active_inIBAFB:FBgn0036111 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nudt4Rat5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity NOT|enablesISSUniProtKB:Q8R2U61600115GO_REF:0000024UniProtGO_REF:0000024
Nudt4Rat5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity NOT|enablesISONudt4 (Mus musculus)1624291 PMID:21070968RGDPMID:21070968
Nudt4Ratbis(5'-adenosyl)-hexaphosphatase activity enablesIBAFB:FBgn0036111 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratbis(5'-adenosyl)-pentaphosphatase activity enablesIBAPANTHER:PTN000290327 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratdiphosphoinositol-polyphosphate diphosphatase activity enablesISSUniProtKB:Q9NZJ91600115GO_REF:0000024UniProtGO_REF:0000024
Nudt4Ratdiphosphoinositol-polyphosphate diphosphatase activity enablesIEAEC:3.6.1.521600115GO_REF:0000003UniProtGO_REF:0000003
Nudt4Ratdiphosphoinositol-polyphosphate diphosphatase activity enablesIBAFB:FBgn0036111 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Ratdiphosphoinositol-polyphosphate diphosphatase activity enablesISONUDT4 (Homo sapiens)1624291 PMID:10777568RGDPMID:10777568
Nudt4Ratendopolyphosphatase activity enablesIBAPANTHER:PTN000290327 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nudt4Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Nudt4Rathydrolase activity enablesIEAInterPro:IPR0200841600115GO_REF:0000002InterProGO_REF:0000002
Nudt4Ratinositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity enablesIEARHEA:563121600115GO_REF:0000116RHEAGO_REF:0000116
Nudt4Ratinositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity enablesIEARHEA:223841600115GO_REF:0000116RHEAGO_REF:0000116
Nudt4Ratinositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity enablesIEARHEA:595001600115GO_REF:0000116RHEAGO_REF:0000116
Nudt4Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Nudt4Ratprotein binding enablesISONUDT4 (Homo sapiens)1624291UniProtKB:O76024 more ...RGDPMID:25416956 more ...
Nudt4Ratpyrophosphatase activity enablesIEAInterPro:IPR0471981600115GO_REF:0000002InterProGO_REF:0000002
Nudt4RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Nudt4RatsnoRNA binding enablesISSUniProtKB:Q8R2U61600115GO_REF:0000024UniProtGO_REF:0000024
Nudt4RatsnoRNA binding enablesISONudt4 (Mus musculus)1624291 PMID:21070968RGDPMID:21070968
1 to 20 of 21 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy. Hua LV, etal., Neuropsychopharmacology 2001 Jun;24(6):640-51.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10777568   PMID:21070968  



Nudt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8732,074,978 - 32,091,491 (-)NCBIGRCr8
mRatBN7.2730,188,100 - 30,204,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,188,100 - 30,204,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,174,576 - 32,191,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,348,209 - 34,364,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0734,123,196 - 34,139,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,643,916 - 36,660,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,695,609 - 36,712,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,753,728 - 32,769,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,773,998 - 32,790,224NCBI
Celera727,261,241 - 27,277,464 (-)NCBICelera
Cytogenetic Map7q13NCBI
NUDT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381293,377,925 - 93,408,146 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1293,377,883 - 93,408,146 (+)EnsemblGRCh38hg38GRCh38
GRCh371293,771,701 - 93,801,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361292,295,832 - 92,321,155 (+)NCBINCBI36Build 36hg18NCBI36
Build 341292,274,169 - 92,302,519NCBI
Celera1293,442,852 - 93,467,713 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1290,838,980 - 90,863,685 (+)NCBIHuRef
CHM1_11293,736,652 - 93,761,972 (+)NCBICHM1_1
T2T-CHM13v2.01293,358,899 - 93,389,124 (+)NCBIT2T-CHM13v2.0
Nudt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,382,869 - 95,400,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,382,869 - 95,400,008 (-)EnsemblGRCm39 Ensembl
GRCm381095,547,007 - 95,564,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,547,007 - 95,564,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv371095,009,641 - 95,026,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,976,977 - 94,993,834 (-)NCBIMGSCv36mm8
Celera1097,522,698 - 97,539,519 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.42NCBI
Nudt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540530,228,072 - 30,234,683 (+)NCBIChiLan1.0ChiLan1.0
NUDT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210101,420,265 - 101,444,233 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112101,416,726 - 101,440,627 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01290,920,449 - 90,944,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,323,929 - 94,347,414 (+)NCBIpanpan1.1PanPan1.1panPan2
NUDT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,627,441 - 33,644,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1533,627,846 - 33,641,795 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,078,975 - 34,095,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,299,028 - 34,315,643 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,298,875 - 34,315,304 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11533,577,609 - 33,594,223 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,666,908 - 33,683,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01533,931,202 - 33,947,815 (+)NCBIUU_Cfam_GSD_1.0
Nudt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,366,673 - 26,373,448 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365079,861,971 - 9,868,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUDT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1589,714,012 - 89,728,260 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,643,052 - 93,657,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUDT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11188,779,771 - 88,803,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037156,359,494 - 156,383,240 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nudt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475013,474,932 - 13,493,950 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Nudt4
137 total Variants

Predicted Target Of
Summary Value
Count of predictions:743
Count of miRNA genes:296
Interacting mature miRNAs:386
Transcripts:ENSRNOT00000012363
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat

1 to 10 of 32 rows
RH129315  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2730,188,142 - 30,188,339 (+)MAPPERmRatBN7.2
Rnor_6.0736,643,959 - 36,644,155NCBIRnor6.0
Rnor_5.0736,695,652 - 36,695,848UniSTSRnor5.0
RGSC_v3.4732,753,771 - 32,753,967UniSTSRGSC3.4
Celera727,261,284 - 27,261,480UniSTS
Cytogenetic Map7q13UniSTS
RH137140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2730,188,294 - 30,188,487 (+)MAPPERmRatBN7.2
Rnor_6.0736,644,111 - 36,644,303NCBIRnor6.0
Rnor_5.0736,695,804 - 36,695,996UniSTSRnor5.0
RGSC_v3.4732,753,923 - 32,754,115UniSTSRGSC3.4
Celera727,261,436 - 27,261,628UniSTS
RH 3.4 Map7233.3UniSTS
Cytogenetic Map7q13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000012363   ⟹   ENSRNOP00000012363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,124 - 30,204,615 (-)Ensembl
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104209   ⟹   ENSRNOP00000078797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,124 - 30,204,615 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105881   ⟹   ENSRNOP00000077626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,100 - 30,193,778 (-)Ensembl
RefSeq Acc Id: NM_001399417   ⟹   NP_001386346
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8732,074,978 - 32,091,491 (-)NCBI
mRatBN7.2730,188,100 - 30,204,615 (-)NCBI
RefSeq Acc Id: NM_053598   ⟹   NP_446050
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8732,074,978 - 32,091,491 (-)NCBI
mRatBN7.2730,188,100 - 30,204,615 (-)NCBI
Rnor_6.0736,643,916 - 36,660,141 (-)NCBI
Rnor_5.0736,695,609 - 36,712,030 (-)NCBI
RGSC_v3.4732,753,728 - 32,769,953 (-)RGD
Celera727,261,241 - 27,277,464 (-)RGD
Sequence:
Protein RefSeqs NP_001386346 (Get FASTA)   NCBI Sequence Viewer  
  NP_446050 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK29279 (Get FASTA)   NCBI Sequence Viewer  
  AFN80335 (Get FASTA)   NCBI Sequence Viewer  
  EDM16850 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012363
  ENSRNOP00000078797
GenBank Protein Q99MY2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446050   ⟸   NM_053598
- Peptide Label: isoform 2
- UniProtKB: Q99MY2 (UniProtKB/Swiss-Prot),   A6IG47 (UniProtKB/TrEMBL),   A0A8I5ZLI5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012363   ⟸   ENSRNOT00000012363
Ensembl Acc Id: ENSRNOP00000077626   ⟸   ENSRNOT00000105881
Ensembl Acc Id: ENSRNOP00000078797   ⟸   ENSRNOT00000104209
RefSeq Acc Id: NP_001386346   ⟸   NM_001399417
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZLI5 (UniProtKB/TrEMBL)
Nudix hydrolase

Name Modeler Protein Id AA Range Protein Structure
AF-Q99MY2-F1-model_v2 AlphaFold Q99MY2 1-179 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34332 BioCyc
Ensembl Genes ENSRNOG00000009094 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000012363 ENTREZGENE
  ENSRNOT00000104209 ENTREZGENE
Gene3D-CATH Nucleoside Triphosphate Pyrophosphohydrolase UniProtKB/Swiss-Prot
InterPro DDP-like_NUDIX UniProtKB/Swiss-Prot
  NUDIX_hydrolase-like_dom_sf UniProtKB/Swiss-Prot
  NUDIX_hydrolase_CS UniProtKB/Swiss-Prot
  NUDIX_hydrolase_dom UniProtKB/Swiss-Prot
KEGG Report rno:94267 UniProtKB/Swiss-Prot
NCBI Gene 94267 ENTREZGENE
PANTHER DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE UniProtKB/Swiss-Prot
  DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED UniProtKB/Swiss-Prot
Pfam NUDIX UniProtKB/Swiss-Prot
PhenoGen Nudt4 PhenoGen
PROSITE NUDIX UniProtKB/Swiss-Prot
  NUDIX_BOX UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009094 RatGTEx
Superfamily-SCOP SSF55811 UniProtKB/Swiss-Prot
UniProt A0A8I5YCF8_RAT UniProtKB/TrEMBL
  A0A8I5ZLI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q5G6_RAT UniProtKB/TrEMBL
  A6IG47 ENTREZGENE, UniProtKB/TrEMBL
  NUDT4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Nudt4  nudix hydrolase 4  Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4  Nudt4_predicted  nudix (nucleoside diphosphate linked moiety X)-type motif 4 (predicted)  Data merged from RGD:1309814 737654 APPROVED
2005-01-20 Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4    diphosphoinositol polyphosphate phosphohydolase type II  Name updated 1299863 APPROVED
2005-01-12 Nudt4_predicted  nudix (nucleoside diphosphate linked moiety X)-type motif 4 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Nudt4  diphosphoinositol polyphosphate phosphohydolase type II      Symbol and Name status set to provisional 70820 PROVISIONAL