Nudt4 (nudix hydrolase 4) - Rat Genome Database

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Gene: Nudt4 (nudix hydrolase 4) Rattus norvegicus
Analyze
Symbol: Nudt4
Name: nudix hydrolase 4
RGD ID: 621355
Description: Predicted to enable pyrophosphatase activity and snoRNA binding activity. Predicted to be involved in diphosphoinositol polyphosphate metabolic process and nucleotide catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including NUDT4 (nudix hydrolase 4); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; diphosphoinositol polyphosphate phosphohydolase type II; diphosphoinositol polyphosphate phosphohydrolase 2; DIPP-2; DRCF-5; LOC360416; nucleoside diphosphate-linked moiety X motif 4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; nudix motif 4; nudix-type motif 4; rDIPP2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2730,188,100 - 30,204,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,188,100 - 30,204,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,174,576 - 32,191,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,348,209 - 34,364,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0734,123,196 - 34,139,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,643,916 - 36,660,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,695,609 - 36,712,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,753,728 - 32,769,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,773,998 - 32,790,224NCBI
Celera727,261,241 - 27,277,464 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (EXP)
buspirone  (EXP)
C60 fullerene  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
formaldehyde  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
kainic acid  (ISO)
ketoconazole  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
methapyrilene  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
Soman  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (ISO)
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy. Hua LV, etal., Neuropsychopharmacology 2001 Jun;24(6):640-51.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10777568   PMID:21070968  


Genomics

Comparative Map Data
Nudt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2730,188,100 - 30,204,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,188,100 - 30,204,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,174,576 - 32,191,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,348,209 - 34,364,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0734,123,196 - 34,139,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,643,916 - 36,660,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,695,609 - 36,712,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,753,728 - 32,769,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,773,998 - 32,790,224NCBI
Celera727,261,241 - 27,277,464 (-)NCBICelera
Cytogenetic Map7q13NCBI
NUDT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381293,377,925 - 93,408,146 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1293,377,883 - 93,408,146 (+)EnsemblGRCh38hg38GRCh38
GRCh371293,771,701 - 93,801,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361292,295,832 - 92,321,155 (+)NCBINCBI36Build 36hg18NCBI36
Build 341292,274,169 - 92,302,519NCBI
Celera1293,442,852 - 93,467,713 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1290,838,980 - 90,863,685 (+)NCBIHuRef
CHM1_11293,736,652 - 93,761,972 (+)NCBICHM1_1
T2T-CHM13v2.01293,358,899 - 93,389,124 (+)NCBIT2T-CHM13v2.0
Nudt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,382,869 - 95,400,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,382,869 - 95,400,008 (-)EnsemblGRCm39 Ensembl
GRCm381095,547,007 - 95,564,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,547,007 - 95,564,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv371095,009,641 - 95,026,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,976,977 - 94,993,834 (-)NCBIMGSCv36mm8
Celera1097,522,698 - 97,539,519 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.42NCBI
Nudt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540530,228,072 - 30,234,683 (+)NCBIChiLan1.0ChiLan1.0
NUDT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan112101,416,726 - 101,440,627 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01290,920,449 - 90,944,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,323,929 - 94,347,414 (+)NCBIpanpan1.1PanPan1.1panPan2
NUDT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,627,441 - 33,644,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1533,627,846 - 33,641,795 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,078,975 - 34,095,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,299,028 - 34,315,643 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,298,875 - 34,315,304 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11533,577,609 - 33,594,223 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,666,908 - 33,683,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01533,931,202 - 33,947,815 (+)NCBIUU_Cfam_GSD_1.0
Nudt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,366,673 - 26,373,448 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365079,861,971 - 9,868,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUDT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1589,714,012 - 89,728,260 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,643,052 - 93,657,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUDT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11188,779,771 - 88,803,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037156,359,494 - 156,383,240 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nudt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475013,474,932 - 13,493,950 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nudt4
129 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:743
Count of miRNA genes:296
Interacting mature miRNAs:386
Transcripts:ENSRNOT00000012363
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat

Markers in Region
RH129315  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2730,188,142 - 30,188,339 (+)MAPPERmRatBN7.2
Rnor_6.0736,643,959 - 36,644,155NCBIRnor6.0
Rnor_5.0736,695,652 - 36,695,848UniSTSRnor5.0
RGSC_v3.4732,753,771 - 32,753,967UniSTSRGSC3.4
Celera727,261,284 - 27,261,480UniSTS
Cytogenetic Map7q13UniSTS
RH137140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2730,188,294 - 30,188,487 (+)MAPPERmRatBN7.2
Rnor_6.0736,644,111 - 36,644,303NCBIRnor6.0
Rnor_5.0736,695,804 - 36,695,996UniSTSRnor5.0
RGSC_v3.4732,753,923 - 32,754,115UniSTSRGSC3.4
Celera727,261,436 - 27,261,628UniSTS
RH 3.4 Map7233.3UniSTS
Cytogenetic Map7q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012363   ⟹   ENSRNOP00000012363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,124 - 30,204,615 (-)Ensembl
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104209   ⟹   ENSRNOP00000078797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,124 - 30,204,615 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105881   ⟹   ENSRNOP00000077626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl730,188,100 - 30,193,778 (-)Ensembl
RefSeq Acc Id: NM_001399417   ⟹   NP_001386346
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2730,188,100 - 30,204,615 (-)NCBI
RefSeq Acc Id: NM_053598   ⟹   NP_446050
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2730,188,100 - 30,204,615 (-)NCBI
Rnor_6.0736,643,916 - 36,660,141 (-)NCBI
Rnor_5.0736,695,609 - 36,712,030 (-)NCBI
RGSC_v3.4732,753,728 - 32,769,953 (-)RGD
Celera727,261,241 - 27,277,464 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001386346 (Get FASTA)   NCBI Sequence Viewer  
  NP_446050 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK29279 (Get FASTA)   NCBI Sequence Viewer  
  AFN80335 (Get FASTA)   NCBI Sequence Viewer  
  EDM16850 (Get FASTA)   NCBI Sequence Viewer  
  Q99MY2 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_446050   ⟸   NM_053598
- Peptide Label: isoform 2
- UniProtKB: Q99MY2 (UniProtKB/Swiss-Prot),   A6IG47 (UniProtKB/TrEMBL),   A0A8I5ZLI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012363   ⟸   ENSRNOT00000012363
RefSeq Acc Id: ENSRNOP00000077626   ⟸   ENSRNOT00000105881
RefSeq Acc Id: ENSRNOP00000078797   ⟸   ENSRNOT00000104209
RefSeq Acc Id: NP_001386346   ⟸   NM_001399417
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZLI5 (UniProtKB/TrEMBL)
Protein Domains
Nudix hydrolase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MY2-F1-model_v2 AlphaFold Q99MY2 1-179 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621355 AgrOrtholog
BioCyc Gene G2FUF-34332 BioCyc
Ensembl Genes ENSRNOG00000009094 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000012363 ENTREZGENE
  ENSRNOP00000012363.4 UniProtKB/TrEMBL
  ENSRNOP00000077626.1 UniProtKB/TrEMBL
  ENSRNOP00000078797 ENTREZGENE
  ENSRNOP00000078797.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012363 ENTREZGENE
  ENSRNOT00000012363.5 UniProtKB/TrEMBL
  ENSRNOT00000104209 ENTREZGENE
  ENSRNOT00000104209.1 UniProtKB/TrEMBL
  ENSRNOT00000105881.1 UniProtKB/TrEMBL
Gene3D-CATH Nucleoside Triphosphate Pyrophosphohydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DDP-like_NUDIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_hydrolase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_hydrolase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_hydrolase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94267 UniProtKB/Swiss-Prot
NCBI Gene 94267 ENTREZGENE
PANTHER DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam NUDIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nudt4 PhenoGen
PROSITE NUDIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_BOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55811 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YCF8_RAT UniProtKB/TrEMBL
  A0A8I5ZLI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q5G6_RAT UniProtKB/TrEMBL
  A6IG47 ENTREZGENE, UniProtKB/TrEMBL
  NUDT4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Nudt4  nudix hydrolase 4  Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4  Nudt4_predicted  nudix (nucleoside diphosphate linked moiety X)-type motif 4 (predicted)  Data Merged 737654 APPROVED
2005-01-20 Nudt4  nudix (nucleoside diphosphate linked moiety X)-type motif 4    diphosphoinositol polyphosphate phosphohydolase type II  Name updated 1299863 APPROVED
2005-01-12 Nudt4_predicted  nudix (nucleoside diphosphate linked moiety X)-type motif 4 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Nudt4  diphosphoinositol polyphosphate phosphohydolase type II      Symbol and Name status set to provisional 70820 PROVISIONAL