Nudt4 (nudix hydrolase 4) - Rat Genome Database

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Gene: Nudt4 (nudix hydrolase 4) Ictidomys tridecemlineatus
Analyze
Symbol: Nudt4
Name: nudix hydrolase 4
RGD ID: 12732062
Description: ENCODES a protein that exhibits 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity (ortholog); INVOLVED IN adenosine 5'-(hexahydrogen pentaphosphate) catabolic process (inferred); diadenosine hexaphosphate catabolic process (inferred); diadenosine pentaphosphate catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: diphosphoinositol polyphosphate phosphohydrolase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,366,673 - 26,373,448 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365079,861,971 - 9,868,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nudt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,366,673 - 26,373,448 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365079,861,971 - 9,868,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUDT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381293,377,925 - 93,408,146 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1293,377,883 - 93,408,146 (+)EnsemblGRCh38hg38GRCh38
GRCh371293,771,701 - 93,801,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361292,295,832 - 92,321,155 (+)NCBINCBI36Build 36hg18NCBI36
Build 341292,274,169 - 92,302,519NCBI
Celera1293,442,852 - 93,467,713 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1290,838,980 - 90,863,685 (+)NCBIHuRef
CHM1_11293,736,652 - 93,761,972 (+)NCBICHM1_1
T2T-CHM13v2.01293,358,899 - 93,389,124 (+)NCBIT2T-CHM13v2.0
Nudt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,382,869 - 95,400,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,382,869 - 95,400,008 (-)EnsemblGRCm39 Ensembl
GRCm381095,547,007 - 95,564,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,547,007 - 95,564,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv371095,009,641 - 95,026,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,976,977 - 94,993,834 (-)NCBIMGSCv36mm8
Celera1097,522,698 - 97,539,519 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.42NCBI
Nudt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8732,074,978 - 32,091,491 (-)NCBIGRCr8
mRatBN7.2730,188,100 - 30,204,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,188,100 - 30,204,615 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx732,174,576 - 32,191,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,348,209 - 34,364,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0734,123,196 - 34,139,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,643,916 - 36,660,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,643,916 - 36,660,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,695,609 - 36,712,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,753,728 - 32,769,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,773,998 - 32,790,224NCBI
Celera727,261,241 - 27,277,464 (-)NCBICelera
Cytogenetic Map7q13NCBI
Nudt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540530,228,072 - 30,234,683 (+)NCBIChiLan1.0ChiLan1.0
NUDT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210101,420,265 - 101,444,233 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112101,416,726 - 101,440,627 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01290,920,449 - 90,944,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,323,929 - 94,347,414 (+)NCBIpanpan1.1PanPan1.1panPan2
NUDT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,627,441 - 33,644,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1533,627,846 - 33,641,795 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,078,975 - 34,095,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,299,028 - 34,315,643 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,298,875 - 34,315,304 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11533,577,609 - 33,594,223 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,666,908 - 33,683,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01533,931,202 - 33,947,815 (+)NCBIUU_Cfam_GSD_1.0
NUDT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1589,714,012 - 89,728,260 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,643,052 - 93,657,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUDT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11188,779,771 - 88,803,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037156,359,494 - 156,383,240 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nudt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475013,474,932 - 13,493,950 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_013358228   ⟹   XP_013213682
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494526,366,673 - 26,373,447 (-)NCBI
SpeTri2.0NW_0049365079,861,972 - 9,868,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358229   ⟹   XP_013213683
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494526,366,673 - 26,373,448 (-)NCBI
SpeTri2.0NW_0049365079,861,971 - 9,868,763 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013213682 (Get FASTA)   NCBI Sequence Viewer  
  XP_013213683 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023468.2
RefSeq Acc Id: XP_013213682   ⟸   XM_013358228
- Peptide Label: isoform X1
- UniProtKB: I3NGH1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013213683   ⟸   XM_013358229
- Peptide Label: isoform X2
- UniProtKB: I3NGH1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Nudix hydrolase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020306 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024431.2 UniProtKB/TrEMBL
Gene3D-CATH Nucleoside Triphosphate Pyrophosphohydrolase UniProtKB/TrEMBL
InterPro DDP-like_NUDIX UniProtKB/TrEMBL
  NUDIX_hydrolase-like_dom_sf UniProtKB/TrEMBL
  NUDIX_hydrolase_CS UniProtKB/TrEMBL
  NUDIX_hydrolase_dom UniProtKB/TrEMBL
NCBI Gene Nudt4 ENTREZGENE
PANTHER DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE UniProtKB/TrEMBL
  NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam NUDIX UniProtKB/TrEMBL
PROSITE NUDIX UniProtKB/TrEMBL
  NUDIX_BOX UniProtKB/TrEMBL
Superfamily-SCOP SSF55811 UniProtKB/TrEMBL
UniProt I3NGH1 ENTREZGENE, UniProtKB/TrEMBL