Cpq (carboxypeptidase Q) - Rat Genome Database

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Gene: Cpq (carboxypeptidase Q) Rattus norvegicus
Analyze
Symbol: Cpq
Name: carboxypeptidase Q
RGD ID: 628610
Description: Predicted to enable metallodipeptidase activity and protein homodimerization activity. Involved in proteolysis; thyroid hormone generation; and tissue regeneration. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and lysosome. Orthologous to human CPQ (carboxypeptidase Q); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 1-nitropropane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hematopoietic lineage switch 2 related protein; hls2-rp; LAL; lal-1; liver annexin like-1; liver annexin-like protein 1; Pgcp; plasma glutamate carboxypeptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8766,148,973 - 66,719,189 (+)NCBIGRCr8
mRatBN7.2764,264,025 - 64,830,867 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl764,264,081 - 64,724,546 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx766,153,454 - 66,613,812 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0768,355,666 - 68,815,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0768,144,621 - 68,604,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0771,709,174 - 72,167,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl771,709,157 - 72,167,417 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,880,847 - 71,975,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0772,004,374 - 72,338,527 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4768,430,069 - 68,900,500 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1768,450,798 - 68,921,230 (+)NCBI
Celera761,386,725 - 61,844,888 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1,4-dioxane  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropropane  (EXP)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-diaminotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-nitro-p-phenylenediamine  (EXP)
2-nitropropane  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-acetylaminofluorene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-nitro-1,2-phenylenediamine  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fucoxanthin  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (ISO)
glyphosate  (EXP)
L-ethionine  (EXP)
lead(0)  (ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nimesulide  (EXP)
O-methyleugenol  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. lal-1: a differentially expressed novel gene during proliferation in liver regeneration and in hepatoma cells. Della Fazia MA, etal., Genes Cells 2002 Nov;7(11):1183-90.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. Cathepsin C and plasma glutamate carboxypeptidase secreted from Fischer rat thyroid cells liberate thyroxin from the N-terminus of thyroglobulin. Suban D, etal., Biochimie. 2012 Mar;94(3):719-26. doi: 10.1016/j.biochi.2011.10.018. Epub 2011 Nov 20.
Additional References at PubMed
PMID:10206990   PMID:12675526   PMID:20551380   PMID:23376485   PMID:23533145   PMID:24006456   PMID:29514215  


Genomics

Comparative Map Data
Cpq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8766,148,973 - 66,719,189 (+)NCBIGRCr8
mRatBN7.2764,264,025 - 64,830,867 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl764,264,081 - 64,724,546 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx766,153,454 - 66,613,812 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0768,355,666 - 68,815,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0768,144,621 - 68,604,278 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0771,709,174 - 72,167,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl771,709,157 - 72,167,417 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,880,847 - 71,975,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0772,004,374 - 72,338,527 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4768,430,069 - 68,900,500 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1768,450,798 - 68,921,230 (+)NCBI
Celera761,386,725 - 61,844,888 (+)NCBICelera
Cytogenetic Map7q22NCBI
CPQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38896,645,242 - 97,143,501 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl896,645,242 - 97,149,654 (+)EnsemblGRCh38hg38GRCh38
GRCh37897,657,470 - 98,155,729 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36897,726,675 - 98,224,900 (+)NCBINCBI36Build 36hg18NCBI36
Build 34897,726,674 - 98,224,898NCBI
Celera893,843,723 - 94,341,990 (+)NCBICelera
Cytogenetic Map8q22.1NCBI
HuRef892,862,971 - 93,361,718 (+)NCBIHuRef
CHM1_1897,697,957 - 98,196,225 (+)NCBICHM1_1
T2T-CHM13v2.0897,770,966 - 98,269,215 (+)NCBIT2T-CHM13v2.0
Cpq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391533,083,275 - 33,594,698 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1533,083,275 - 33,594,698 (+)EnsemblGRCm39 Ensembl
GRCm381533,083,129 - 33,594,552 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1533,083,129 - 33,594,552 (+)EnsemblGRCm38mm10GRCm38
MGSCv371533,012,884 - 33,524,307 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361533,027,787 - 33,539,093 (+)NCBIMGSCv36mm8
Celera1533,743,973 - 34,239,581 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1513.74NCBI
Cpq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541712,585,722 - 13,024,655 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541712,585,829 - 13,020,935 (+)NCBIChiLan1.0ChiLan1.0
CPQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27113,971,190 - 114,596,821 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1889,510,729 - 90,136,463 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0893,264,536 - 93,883,201 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1895,461,027 - 95,974,029 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl895,599,177 - 95,974,029 (+)Ensemblpanpan1.1panPan2
CPQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12941,058,641 - 41,461,567 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2941,058,306 - 41,461,563 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02941,286,374 - 41,655,798 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2941,130,486 - 41,655,802 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12941,328,033 - 41,695,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02941,296,426 - 41,666,684 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02941,790,780 - 42,130,099 (+)NCBIUU_Cfam_GSD_1.0
Cpq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530338,063,459 - 38,513,392 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647045,485,926 - 45,848,416 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647045,489,562 - 45,848,412 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl439,480,676 - 39,967,629 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1439,492,663 - 39,855,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2442,482,480 - 42,670,723 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2442,758,536 - 42,938,686 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1891,604,736 - 92,095,671 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl891,738,987 - 92,097,126 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603948,675,637 - 49,182,115 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247634,051,605 - 4,450,491 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247633,943,816 - 4,482,111 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cpq
2305 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:93
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000008211
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat

Markers in Region
RH127776  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2764,724,226 - 64,724,425 (+)MAPPERmRatBN7.2
Rnor_6.0772,167,091 - 72,167,289NCBIRnor6.0
Rnor_5.0772,338,211 - 72,338,409UniSTSRnor5.0
RGSC_v3.4768,900,184 - 68,900,382UniSTSRGSC3.4
Celera761,844,572 - 61,844,770UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000008211   ⟹   ENSRNOP00000008211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl764,264,159 - 64,724,546 (+)Ensembl
Rnor_6.0 Ensembl771,709,157 - 72,167,417 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112011   ⟹   ENSRNOP00000095981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl764,264,081 - 64,634,621 (+)Ensembl
RefSeq Acc Id: NM_031640   ⟹   NP_113828
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8766,149,398 - 66,609,736 (+)NCBI
mRatBN7.2764,264,180 - 64,724,543 (+)NCBI
Rnor_6.0771,709,339 - 72,167,407 (+)NCBI
Rnor_5.0771,880,847 - 71,975,396 (+)NCBI
Rnor_5.0772,004,374 - 72,338,527 (+)NCBI
RGSC_v3.4768,430,069 - 68,900,500 (+)RGD
Celera761,386,725 - 61,844,888 (+)RGD
Sequence:
RefSeq Acc Id: XM_008765417   ⟹   XP_008763639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8766,148,973 - 66,609,739 (+)NCBI
mRatBN7.2764,264,027 - 64,724,549 (+)NCBI
Rnor_6.0771,709,174 - 72,167,413 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079808   ⟹   XP_038935736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8766,149,032 - 66,719,189 (+)NCBI
mRatBN7.2764,264,025 - 64,830,867 (+)NCBI
RefSeq Acc Id: NP_113828   ⟸   NM_031640
- Peptide Label: precursor
- UniProtKB: A0A8I6AKX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763639   ⟸   XM_008765417
- Peptide Label: isoform X1
- UniProtKB: Q9JLV0 (UniProtKB/Swiss-Prot),   Q9Z1Y1 (UniProtKB/Swiss-Prot),   Q6IRK9 (UniProtKB/Swiss-Prot),   A6HQY8 (UniProtKB/TrEMBL),   A0A8I6AKX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008211   ⟸   ENSRNOT00000008211
RefSeq Acc Id: XP_038935736   ⟸   XM_039079808
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AKX5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095981   ⟸   ENSRNOT00000112011
Protein Domains
Peptidase M28

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IRK9-F1-model_v2 AlphaFold Q6IRK9 1-472 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695277
Promoter ID:EPDNEW_R5802
Type:initiation region
Name:Cpq_1
Description:carboxypeptidase Q
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0771,709,318 - 71,709,378EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628610 AgrOrtholog
BioCyc Gene G2FUF-33703 BioCyc
Ensembl Genes ENSRNOG00000005931 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055026477 UniProtKB/Swiss-Prot
  ENSRNOG00060009425 UniProtKB/Swiss-Prot
  ENSRNOG00065016771 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008211.7 UniProtKB/Swiss-Prot
  ENSRNOT00000112011.1 UniProtKB/TrEMBL
  ENSRNOT00055045680 UniProtKB/Swiss-Prot
  ENSRNOT00060015923 UniProtKB/Swiss-Prot
  ENSRNOT00065027983 UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.30.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn peptidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7098277 IMAGE-MGC_LOAD
InterPro CPQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:58952 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91627 IMAGE-MGC_LOAD
NCBI Gene 58952 ENTREZGENE
PANTHER CARBOXYPEPTIDASE Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12053 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cpq PhenoGen
RatGTEx ENSRNOG00000005931 RatGTEx
  ENSRNOG00055026477 RatGTEx
  ENSRNOG00060009425 RatGTEx
  ENSRNOG00065016771 RatGTEx
Superfamily-SCOP Zn-dependent exopeptidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AKX5 ENTREZGENE, UniProtKB/TrEMBL
  A6HQY8 ENTREZGENE, UniProtKB/TrEMBL
  CBPQ_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JLV0 ENTREZGENE
  Q9Z1Y1 ENTREZGENE
UniProt Secondary Q9JLV0 UniProtKB/Swiss-Prot
  Q9Z1Y1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Cpq  carboxypeptidase Q  Pgcp  plasma glutamate carboxypeptidase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pgcp  plasma glutamate carboxypeptidase      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Pgcp  plasma glutamate carboxypeptidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression transcript undetectable in normal liver, but over-expressed in liver regeneration 633681