Plk5 (polo-like kinase 5) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Plk5 (polo-like kinase 5) Rattus norvegicus
Analyze
Symbol: Plk5
Name: polo-like kinase 5
RGD ID: 1305038
Description: Predicted to enable ATP binding activity. Predicted to be involved in several processes, including defense response to tumor cell; mitotic spindle organization; and regulation of G1/S transition of mitotic cell cycle. Predicted to be located in nucleolus. Predicted to be active in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Orthologous to human PLK5 (polo like kinase 5 (inactive)); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inactive serine/threonine-protein kinase PLK5; LOC314627; Plk5p; polo-like kinase 5 pseudogene; RGD1305038; serine/threonine-protein kinase PLK5; similar to Serine/threonine-protein kinase SNK (Serum inducible kinase)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,997,453 - 10,006,959 (-)NCBIGRCr8
mRatBN7.279,346,777 - 9,367,923 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,346,777 - 9,355,196 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,223,648 - 12,232,091 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,098,988 - 14,107,431 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,966,317 - 11,974,816 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,212,910 - 12,234,253 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,212,911 - 12,221,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,382,705 - 12,391,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,858,118 - 10,866,430 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,858,316 - 10,874,502 (-)NCBI
Celera77,523,892 - 7,531,997 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IBA)
cytoplasm  (IBA,ISO)
kinetochore  (IBA)
nucleolus  (ISO)
nucleus  (IBA)
spindle pole  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20100802   PMID:21245385  


Genomics

Comparative Map Data
Plk5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,997,453 - 10,006,959 (-)NCBIGRCr8
mRatBN7.279,346,777 - 9,367,923 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,346,777 - 9,355,196 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,223,648 - 12,232,091 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,098,988 - 14,107,431 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,966,317 - 11,974,816 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,212,910 - 12,234,253 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,212,911 - 12,221,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,382,705 - 12,391,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,858,118 - 10,866,430 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,858,316 - 10,874,502 (-)NCBI
Celera77,523,892 - 7,531,997 (-)NCBICelera
Cytogenetic Map7q11NCBI
PLK5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,524,077 - 1,536,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,508,023 - 1,536,046 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,524,076 - 1,536,045 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,475,079 - 1,486,455 (+)NCBINCBI36Build 36hg18NCBI36
Celera191,458,103 - 1,469,377 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,298,745 - 1,309,489 (+)NCBIHuRef
CHM1_1191,524,068 - 1,535,220 (+)NCBICHM1_1
T2T-CHM13v2.0191,494,514 - 1,506,275 (+)NCBIT2T-CHM13v2.0
Plk5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,192,293 - 80,201,323 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,192,293 - 80,201,323 (+)EnsemblGRCm39 Ensembl
GRCm381080,356,459 - 80,365,489 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,356,459 - 80,365,489 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,819,204 - 79,828,234 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,759,588 - 79,768,610 (+)NCBIMGSCv36mm8
Celera1081,371,338 - 81,380,211 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Plk5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554956,415,172 - 6,424,445 (-)NCBIChiLan1.0ChiLan1.0
PLK5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,876,086 - 5,899,659 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,119,343 - 5,130,503 (+)NCBINHGRI_mPanPan1
PanPan1.1191,496,205 - 1,506,201 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,497,953 - 1,505,995 (+)Ensemblpanpan1.1panPan2
PLK5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,337,808 - 57,343,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,337,874 - 57,343,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,129,851 - 57,136,106 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,069,085 - 58,075,340 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,068,402 - 58,075,313 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,125,378 - 57,131,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,604,652 - 57,610,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,806,577 - 57,812,829 (-)NCBIUU_Cfam_GSD_1.0
Plk5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,995,919 - 217,009,690 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936588826,473 - 838,818 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLK5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1276,948,062 - 76,956,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,124,259 - 78,132,107 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLK5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,301,199 - 1,309,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660817,540,477 - 7,551,132 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plk5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248287,172,286 - 7,181,564 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plk5
115 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:145
Interacting mature miRNAs:159
Transcripts:ENSRNOT00000042204
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 46 113 86 85 54 25 54 6 208 92 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042204   ⟹   ENSRNOP00000051194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,346,777 - 9,355,196 (-)Ensembl
Rnor_6.0 Ensembl712,212,911 - 12,221,330 (-)Ensembl
RefSeq Acc Id: NM_001170557   ⟹   NP_001164028
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,872 (-)NCBI
mRatBN7.279,346,777 - 9,355,196 (-)NCBI
Rnor_6.0712,212,911 - 12,221,330 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Celera77,523,892 - 7,531,997 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240921   ⟹   XP_006240983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,864 (-)NCBI
mRatBN7.279,346,777 - 9,355,195 (-)NCBI
Rnor_6.0712,212,910 - 12,221,301 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240922   ⟹   XP_006240984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,876 (-)NCBI
mRatBN7.279,346,777 - 9,355,195 (-)NCBI
Rnor_6.0712,212,910 - 12,221,300 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240923   ⟹   XP_006240985
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,864 (-)NCBI
mRatBN7.279,346,777 - 9,355,196 (-)NCBI
Rnor_6.0712,212,910 - 12,221,301 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240925   ⟹   XP_006240987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,999,668 - 10,005,878 (-)NCBI
mRatBN7.279,348,276 - 9,355,196 (-)NCBI
Rnor_6.0712,214,448 - 12,221,302 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765098   ⟹   XP_008763320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,871 (-)NCBI
mRatBN7.279,346,990 - 9,355,195 (-)NCBI
Rnor_6.0712,213,163 - 12,221,302 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765099   ⟹   XP_008763321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,785 (-)NCBI
mRatBN7.279,346,777 - 9,355,187 (-)NCBI
Rnor_6.0712,212,910 - 12,221,206 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079003   ⟹   XP_038934931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,785 (-)NCBI
mRatBN7.279,346,777 - 9,355,188 (-)NCBI
RefSeq Acc Id: XM_039079005   ⟹   XP_038934933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,002,298 (-)NCBI
mRatBN7.279,346,777 - 9,351,715 (-)NCBI
RefSeq Acc Id: XM_063263417   ⟹   XP_063119487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,866 (-)NCBI
RefSeq Acc Id: XM_063263418   ⟹   XP_063119488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,005,862 (-)NCBI
RefSeq Acc Id: XM_063263419   ⟹   XP_063119489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,453 - 10,001,438 (-)NCBI
RefSeq Acc Id: XM_063263420   ⟹   XP_063119490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,001,180 - 10,006,959 (-)NCBI
RefSeq Acc Id: XR_005486602
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,000,504 - 10,005,900 (-)NCBI
mRatBN7.279,349,833 - 9,355,195 (-)NCBI
RefSeq Acc Id: XR_355240
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,806 - 10,005,878 (-)NCBI
mRatBN7.279,346,777 - 9,355,196 (-)NCBI
Rnor_6.0712,212,910 - 12,221,302 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: XR_355241
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,997,764 - 10,005,878 (-)NCBI
mRatBN7.279,347,088 - 9,355,196 (-)NCBI
Rnor_6.0712,213,272 - 12,221,302 (-)NCBI
Rnor_5.0712,382,705 - 12,391,125 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001164028   ⟸   NM_001170557
- UniProtKB: A6K8L7 (UniProtKB/TrEMBL),   A6K8L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240985   ⟸   XM_006240923
- Peptide Label: isoform X4
- UniProtKB: A6K8L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240984   ⟸   XM_006240922
- Peptide Label: isoform X2
- UniProtKB: A6K8L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240983   ⟸   XM_006240921
- Peptide Label: isoform X1
- UniProtKB: D3ZY07 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240987   ⟸   XM_006240925
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008763321   ⟸   XM_008765099
- Peptide Label: isoform X5
- UniProtKB: A6K8L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763320   ⟸   XM_008765098
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000051194   ⟸   ENSRNOT00000042204
RefSeq Acc Id: XP_038934931   ⟸   XM_039079003
- Peptide Label: isoform X8
- UniProtKB: A6K8L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934933   ⟸   XM_039079005
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063119487   ⟸   XM_063263417
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063119488   ⟸   XM_063263418
- Peptide Label: isoform X7
- UniProtKB: A6K8L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119489   ⟸   XM_063263419
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063119490   ⟸   XM_063263420
- Peptide Label: isoform X12
Protein Domains
POLO box   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZY07-F1-model_v2 AlphaFold D3ZY07 1-595 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695020
Promoter ID:EPDNEW_R5545
Type:single initiation site
Name:Plk5_1
Description:polo-like kinase 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,221,301 - 12,221,361EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305038 AgrOrtholog
BioCyc Gene G2FUF-34939 BioCyc
Ensembl Genes ENSRNOG00000034102 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042204 ENTREZGENE
  ENSRNOT00000042204.5 UniProtKB/TrEMBL
  ENSRNOT00000146724 ENTREZGENE
  ENSRNOT00000158969 ENTREZGENE
Gene3D-CATH 3.30.1120.30 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  POLO_box_1 UniProtKB/TrEMBL
  POLO_box_dom_sf UniProtKB/TrEMBL
  POLO_box_duplicated_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:314627 UniProtKB/TrEMBL
NCBI Gene 314627 ENTREZGENE
PANTHER INACTIVE SERINE/THREONINE-PROTEIN KINASE PLK5 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE PLK UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
  POLO_box UniProtKB/TrEMBL
PhenoGen Plk5 PhenoGen
PROSITE POLO_BOX UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000034102 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  Polo-box domain UniProtKB/TrEMBL
UniProt A6K8L7 ENTREZGENE, UniProtKB/TrEMBL
  A6K8L8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZY07 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-12-23 Plk5  polo-like kinase 5  Plk5p  polo-like kinase 5 pseudogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Plk5p  polo-like kinase 5 pseudogene  RGD1305038  similar to Serine/threonine-protein kinase SNK (Serum inducible kinase)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1305038  similar to Serine/threonine-protein kinase SNK (Serum inducible kinase)   RGD1305038_predicted  similar to Serine/threonine-protein kinase SNK (Serum inducible kinase) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1305038_predicted  similar to Serine/threonine-protein kinase SNK (Serum inducible kinase) (predicted)  LOC314627_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314627_predicted  similar to Serine/threonine-protein kinase SNK (Serum inducible kinase) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL