Gene: Gamt (guanidinoacetate N-methyltransferase) Rattus norvegicus
Symbol: Gamt
Name: guanidinoacetate N-methyltransferase
Description: ENCODES a protein that exhibits guanidinoacetate N-methyltransferase activity; protein homodimerization activity; S-adenosylmethionine-dependent methyltransferase activity; INVOLVED IN creatine biosynthetic process; embryonic liver development; S-adenosylhomocysteine metabolic process; PARTICIPATES IN creatine metabolic pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH Amino Acid Metabolism, Inborn Errors (ortholog); cerebral creatine deficiency syndrome (ortholog); Guanidinoacetate Methyltransferase Deficiency (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GMT; guanidinoacetate methyltransferase
Homo sapiens (human) : GAMT (guanidinoacetate N-methyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Gamt (guanidinoacetate methyltransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gamt (guanidinoacetate N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : GAMT (guanidinoacetate N-methyltransferase)
Canis lupus familiaris (dog) : GAMT (guanidinoacetate N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gamt (guanidinoacetate N-methyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0712,314,848 - 12,317,998 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0712,484,097 - 12,487,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,959,990 - 10,962,720 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,959,989 - 10,962,720 (+)NCBI
Celera77,625,330 - 7,628,480 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gamt
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2659
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE