Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gamt (guanidinoacetate N-methyltransferase) Rattus norvegicus
Symbol: Gamt
Name: guanidinoacetate N-methyltransferase
RGD ID: 2659
Description: Exhibits guanidinoacetate N-methyltransferase activity and identical protein binding activity. Involved in S-adenosylmethionine metabolic process; carboxylic acid metabolic process; and embryonic liver development. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Orthologous to human GAMT (guanidinoacetate N-methyltransferase); PARTICIPATES IN creatine metabolic pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GMT; guanidinoacetate methyltransferase
Homo sapiens (human) : GAMT (guanidinoacetate N-methyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Gamt (guanidinoacetate methyltransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gamt (guanidinoacetate N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : GAMT (guanidinoacetate N-methyltransferase)
Canis lupus familiaris (dog) : GAMT (guanidinoacetate N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gamt (guanidinoacetate N-methyltransferase)
Sus scrofa (pig) : GAMT (guanidinoacetate N-methyltransferase)
Chlorocebus sabaeus (African green monkey) : GAMT (guanidinoacetate N-methyltransferase)
Heterocephalus glaber (naked mole-rat) : Gamt (guanidinoacetate N-methyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0712,314,848 - 12,317,998 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,314,848 - 12,317,998 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,484,097 - 12,487,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,959,990 - 10,962,720 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,959,989 - 10,962,720 (+)NCBI
Celera77,625,330 - 7,628,480 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gamt
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2659
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.