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Gene: Atp2b1 (ATPase plasma membrane Ca2+ transporting 1) Rattus norvegicus
Symbol: Atp2b1
Name: ATPase plasma membrane Ca2+ transporting 1
RGD ID: 621303
Description: Exhibits PDZ domain binding activity. Involved in several processes, including animal organ development; calcium ion export; and cellular response to lipid. Localizes to several cellular components, including basolateral plasma membrane; neuronal cell body membrane; and synaptic membrane. Biomarker of hypertension. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: ATPase, Ca++ transporting, plasma membrane 1; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 1; Pmca1; Pmca1a; Pmca1b; Pmca1c
Homo sapiens (human) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)  HGNC  Alliance
Mus musculus (house mouse) : Atp2b1 (ATPase, Ca++ transporting, plasma membrane 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Canis lupus familiaris (dog) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)
Sus scrofa (pig) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Chlorocebus sabaeus (African green monkey) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Heterocephalus glaber (naked mole-rat) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)
more info ...
Allele / Splice: Atp2b1em2Mcwi  
Genetic Models: SS-Atp2b1em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0741,114,606 - 41,223,138 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl741,114,697 - 41,220,579 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0741,153,926 - 41,262,537 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4736,493,661 - 36,600,280 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1736,513,931 - 36,620,551 (+)NCBI
Celera730,753,051 - 30,859,194 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp2b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621303
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.