Or6c76b (olfactory receptor family 6 subfamily C member 76B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or6c76b (olfactory receptor family 6 subfamily C member 76B) Rattus norvegicus
Analyze
Symbol: Or6c76b
Name: olfactory receptor family 6 subfamily C member 76B
RGD ID: 1334198
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6C76 (olfactory receptor family 6 subfamily C member 76); INTERACTS WITH bisphenol A; C60 fullerene; cadmium dichloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 932; olfactory receptor gene Olr932; olfactory receptor Olr932; olfactory receptor pseudogene 1056; olfactory receptor pseudogene Olr1056-ps; Olr1056-ps; Olr932
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr873,765,256 - 3,771,688 (-)NCBIGRCr8
mRatBN7.273,121,741 - 3,122,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.273,121,741 - 3,122,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl73,121,741 - 3,122,676 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx75,984,853 - 5,985,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.077,860,525 - 7,861,460 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.079,026,959 - 9,027,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0716,431,803 - 16,432,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0716,596,143 - 16,597,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.474,386,212 - 4,387,147 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,386,211 - 4,387,147 (-)NCBI
Celera74,676,745 - 4,677,679 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or6c76b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr873,765,256 - 3,771,688 (-)NCBIGRCr8
mRatBN7.273,121,741 - 3,122,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.273,121,741 - 3,122,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl73,121,741 - 3,122,676 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx75,984,853 - 5,985,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.077,860,525 - 7,861,460 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.079,026,959 - 9,027,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0716,431,803 - 16,432,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0716,596,143 - 16,597,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.474,386,212 - 4,387,147 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,386,211 - 4,387,147 (-)NCBI
Celera74,676,745 - 4,677,679 (+)NCBICelera
Cytogenetic Map7q11NCBI
OR6C76
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,426,254 - 55,427,192 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,426,254 - 55,427,192 (+)EnsemblGRCh38hg38GRCh38
GRCh371255,820,038 - 55,820,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,106,305 - 54,107,243 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,106,304 - 54,107,243NCBI
Celera1255,472,093 - 55,473,030 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1252,858,811 - 52,859,748 (+)NCBIHuRef
CHM1_11255,786,836 - 55,787,773 (+)NCBICHM1_1
T2T-CHM13v2.01255,392,802 - 55,393,761 (+)NCBIT2T-CHM13v2.0
Or6c76b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910129,692,389 - 129,693,321 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10129,691,236 - 129,694,591 (+)EnsemblGRCm39 Ensembl
GRCm3810129,856,520 - 129,857,452 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10129,855,367 - 129,858,722 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710129,293,576 - 129,294,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610129,259,469 - 129,260,401 (+)NCBIMGSCv36mm8
Celera10132,242,169 - 132,243,101 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.57NCBI
LOC100683141
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1331,338,984 - 31,339,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha333,331,088 - 33,332,022 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0331,488,907 - 31,489,844 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1331,337,436 - 31,338,370 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0331,263,408 - 31,264,342 (+)NCBIUNSW_CanFamBas_1.0
LOC100620182
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2521,692,500 - 21,693,441 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Or6c76b
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:147
Count of miRNA genes:122
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000049493
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
reproductive system
respiratory system
1 1 1 3 4 3 2 1

Sequence


Ensembl Acc Id: ENSRNOT00000049493   ⟹   ENSRNOP00000049336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl716,431,592 - 16,432,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105744   ⟹   ENSRNOP00000080166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl73,121,741 - 3,122,676 (-)Ensembl
RefSeq Acc Id: NM_001001386   ⟹   NP_001001386
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,770,753 - 3,771,688 (-)NCBI
mRatBN7.273,121,741 - 3,122,676 (-)NCBI
RGSC_v3.474,386,212 - 4,387,147 (-)RGD
Sequence:
RefSeq Acc Id: XM_063264022   ⟹   XP_063120092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,765,256 - 3,771,688 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001001386 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120092 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89102 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000080166.1
RefSeq Acc Id: NP_001001386   ⟸   NM_001001386
- UniProtKB: A0A8I5ZP76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049336   ⟸   ENSRNOT00000049493
Ensembl Acc Id: ENSRNOP00000080166   ⟸   ENSRNOT00000105744
RefSeq Acc Id: XP_063120092   ⟸   XM_063264022
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZWI5-F1-model_v2 AlphaFold D3ZWI5 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334198 AgrOrtholog
BioCyc Gene G2FUF-35251 BioCyc
Ensembl Genes ENSRNOG00000033400 Ensembl
  ENSRNOG00000066966 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000105744.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report rno:366802 UniProtKB/TrEMBL
NCBI Gene 366802 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6C76 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c76b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033400 RatGTEx
  ENSRNOG00000066966 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I5ZP76 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-06 Or6c76b  olfactory receptor family 6 subfamily C member 76B  Olr1056-ps  olfactory receptor pseudogene 1056  Data merged from RGD:1332917 737654 PROVISIONAL
2022-08-16 Or6c76b  olfactory receptor family 6 subfamily C member 76B  Olr932  olfactory receptor 932  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr932  olfactory receptor 932   Olr932_predicted  olfactory receptor 932 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr932_predicted  olfactory receptor 932 (predicted)      Symbol and Name status set to approved 70820 APPROVED
2005-02-04 Olr1056-ps  olfactory receptor pseudogene 1056      Symbol and Name status set to approved 70820 APPROVED