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Gene: Hmga2 (high mobility group AT-hook 2) Rattus norvegicus
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Symbol: Hmga2
Name: high mobility group AT-hook 2
Description: Exhibits enzyme binding activity. Involved in negative regulation of signal transduction; regulation of transcription, DNA-templated; and signal transduction. Localizes to the nucleus. Human ortholog(s) of this gene implicated in leiomyoma; lipoma; ovarian cancer; and uterine fibroid. Orthologous to human HMGA2 (high mobility group AT-hook 2); PARTICIPATES IN Ras mediated signaling pathway; INTERACTS WITH 2-methoxyethanol; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: high mobility group protein HMGI-C; Hmgic; non-histone chromosomal architectural protein HMGI-C
Orthologs:
Homo sapiens (human) : HMGA2 (high mobility group AT-hook 2)  HGNC  Alliance
Mus musculus (house mouse) : Hmga2 (high mobility group AT-hook 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmga2 (high mobility group AT-hook 2)
Canis lupus familiaris (dog) : HMGA2 (high mobility group AT-hook 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmga2 (high mobility group AT-hook 2)
Sus scrofa (pig) : HMGA2 (high mobility group AT-hook 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0765,159,944 - 65,275,408 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0765,375,936 - 65,490,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4759,638,555 - 59,753,791 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1759,659,284 - 59,774,521 (-)NCBI
Celera752,634,133 - 52,748,501 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hmga2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620617
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-07-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.