Plpp2 (phospholipid phosphatase 2) - Rat Genome Database

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Gene: Plpp2 (phospholipid phosphatase 2) Rattus norvegicus
Analyze
Symbol: Plpp2
Name: phospholipid phosphatase 2
RGD ID: 628893
Description: Predicted to enable ceramide-1-phosphate phosphatase activity; phosphatidate phosphatase activity; and sphingosine-1-phosphate phosphatase activity. Involved in regulation of cell cycle G1/S phase transition. Predicted to be located in caveola; early endosome; and endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Orthologous to human PLPP2 (phospholipid phosphatase 2); PARTICIPATES IN D-glycericacidemia pathway; familial lipoprotein lipase deficiency pathway; glycerol kinase deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lipid phosphate phosphohydrolase 2; PAP-2c; PAP2-G; PAP2-gamma; PAP2c; phosphatidate phosphohydrolase type 2c; phosphatidic acid phosphatase 2c; phosphatidic acid phosphatase type 2c; Ppap2c
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2710,175,918 - 10,184,032 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl710,175,948 - 10,184,071 (+)Ensembl
Rnor_6.0713,062,168 - 13,070,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,062,196 - 13,070,280 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,225,606 - 13,233,682 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,694,272 - 11,702,348 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,694,271 - 11,702,348 (+)NCBI
Celera78,341,562 - 8,349,386 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP,ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
etoposide  (ISO)
flutamide  (EXP)
genistein  (ISO)
gentamycin  (EXP)
hexachlorobenzene  (EXP)
lithium chloride  (ISO)
lithocholic acid  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium dichromate  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Lipid phosphate phosphatase-2 activity regulates S-phase entry of the cell cycle in Rat2 fibroblasts. Morris KE, etal., J Biol Chem. 2006 Apr 7;281(14):9297-306. doi: 10.1074/jbc.M511710200. Epub 2006 Feb 8.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile. Zhang N, etal., Genesis 2000 Aug;27(4):137-40.
Additional References at PubMed
PMID:9705349   PMID:15489334  


Genomics

Comparative Map Data
Plpp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2710,175,918 - 10,184,032 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl710,175,948 - 10,184,071 (+)Ensembl
Rnor_6.0713,062,168 - 13,070,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,062,196 - 13,070,280 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,225,606 - 13,233,682 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,694,272 - 11,702,348 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,694,271 - 11,702,348 (+)NCBI
Celera78,341,562 - 8,349,386 (+)NCBICelera
Cytogenetic Map7q11NCBI
PLPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819281,043 - 291,403 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl19281,040 - 291,403 (-)EnsemblGRCh38hg38GRCh38
GRCh3719281,043 - 291,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619232,043 - 242,435 (-)NCBINCBI36hg18NCBI36
Build 3419232,045 - 242,169NCBI
Celera19520,837 - 531,227 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef1951,652 - 61,794 (-)NCBIHuRef
CHM1_119281,584 - 291,992 (-)NCBICHM1_1
T2T-CHM13v2.019232,088 - 242,448 (-)NCBI
Plpp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,362,258 - 79,369,621 (-)NCBIGRCm39mm39
GRCm39 Ensembl1079,362,264 - 79,369,630 (-)Ensembl
GRCm381079,526,424 - 79,533,787 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,526,430 - 79,533,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,989,174 - 78,996,532 (-)NCBIGRCm37mm9NCBIm37
MGSCv361078,930,455 - 78,936,897 (-)NCBImm8
Celera1080,539,736 - 80,547,094 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Plpp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,307,079 - 7,310,955 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554957,307,079 - 7,310,898 (+)NCBIChiLan1.0ChiLan1.0
PLPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12058,083,902 - 58,095,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2058,087,289 - 58,095,421 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,887,253 - 57,898,727 (+)NCBI
ROS_Cfam_1.02058,827,680 - 58,839,197 (+)NCBI
UMICH_Zoey_3.12057,881,535 - 57,893,021 (+)NCBI
UNSW_CanFamBas_1.02058,361,438 - 58,372,906 (+)NCBI
UU_Cfam_GSD_1.02058,564,919 - 58,576,416 (+)NCBI
Plpp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,814,296 - 217,820,361 (+)NCBI
SpeTri2.0NW_00493658814,422 - 20,467 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,945,841 - 77,957,313 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,945,760 - 77,957,318 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2279,284,680 - 79,296,233 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,326 - 26,759 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl614,945 - 26,703 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660819,082,318 - 9,093,896 (+)NCBIVero_WHO_p1.0
Plpp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248288,058,329 - 8,062,677 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248288,058,688 - 8,062,679 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH141062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2710,183,676 - 10,183,894 (+)MAPPERmRatBN7.2
Rnor_6.0713,069,926 - 13,070,143NCBIRnor6.0
Rnor_5.0713,233,328 - 13,233,545UniSTSRnor5.0
RGSC_v3.4711,701,994 - 11,702,211UniSTSRGSC3.4
Celera78,349,032 - 8,349,249UniSTS
RH 3.4 Map716.4UniSTS
Cytogenetic Map7q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:400
Count of miRNA genes:218
Interacting mature miRNAs:251
Transcripts:ENSRNOT00000000193
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 46 38 4 38 4 35 28 5
Low 38 11 3 15 3 2 3 70 7 6 2
Below cutoff 5 6 8 6 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000193   ⟹   ENSRNOP00000000193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,175,948 - 10,184,071 (+)Ensembl
Rnor_6.0 Ensembl713,062,196 - 13,070,280 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115499   ⟹   ENSRNOP00000087524
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,178,306 - 10,184,071 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000120111   ⟹   ENSRNOP00000080173
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,175,957 - 10,184,032 (+)Ensembl
RefSeq Acc Id: NM_139252   ⟹   NP_640345
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2710,175,950 - 10,184,031 (+)NCBI
Rnor_6.0713,062,204 - 13,070,280 (+)NCBI
Rnor_5.0713,225,606 - 13,233,682 (+)NCBI
RGSC_v3.4711,694,272 - 11,702,348 (+)RGD
Celera78,341,562 - 8,349,386 (+)RGD
Sequence:
RefSeq Acc Id: XM_008765155   ⟹   XP_008763377
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2710,175,918 - 10,184,032 (+)NCBI
Rnor_6.0713,062,168 - 13,070,281 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078409   ⟹   XP_038934337
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2710,175,933 - 10,183,063 (+)NCBI
RefSeq Acc Id: XM_039078410   ⟹   XP_038934338
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2710,175,952 - 10,184,032 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_640345   ⟸   NM_139252
- UniProtKB: Q8K593 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008763377   ⟸   XM_008765155
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000000193   ⟸   ENSRNOT00000000193
RefSeq Acc Id: XP_038934337   ⟸   XM_039078409
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934338   ⟸   XM_039078410
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000087524   ⟸   ENSRNOT00000115499
RefSeq Acc Id: ENSRNOP00000080173   ⟸   ENSRNOT00000120111
Protein Domains
acidPPc

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K593-F1-model_v2 AlphaFold Q8K593 1-276 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695061
Promoter ID:EPDNEW_R5585
Type:multiple initiation site
Name:Plpp2_1
Description:phospholipid phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0713,062,204 - 13,062,264EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628893 AgrOrtholog
BioCyc Gene G2FUF-34872 BioCyc
Ensembl Genes ENSRNOG00000000177 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000000193 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000080173.1 UniProtKB/TrEMBL
  ENSRNOP00000087524.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000193 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000115499.1 UniProtKB/TrEMBL
  ENSRNOT00000120111.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5621318 IMAGE-MGC_LOAD
InterPro LPP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxi_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA_PP_rel UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report rno:246115 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72294 IMAGE-MGC_LOAD
NCBI Gene 246115 ENTREZGENE
PANTHER PTHR10165 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10165:SF25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plpp2 PhenoGen
SMART acidPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A7D7_RAT UniProtKB/TrEMBL
  A0A8I6G688_RAT UniProtKB/TrEMBL
  PLPP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-26 Plpp2  phospholipid phosphatase 2  Ppap2c  phosphatidic acid phosphatase type 2c  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ppap2c  phosphatidic acid phosphatase type 2c      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Ppap2c  phosphatidic acid phosphatase type 2c      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology D. melanogastar homolog is a negative regulator of primordial germ cell migration 724585