Gene: Sv2a (synaptic vesicle glycoprotein 2a) Rattus norvegicus
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Symbol: Sv2a
Name: synaptic vesicle glycoprotein 2a
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN regulation of gamma-aminobutyric acid secretion; cellular calcium ion homeostasis (ortholog); synaptic vesicle priming (ortholog); PARTICIPATES IN cell-extracellular matrix signaling pathway; ASSOCIATED WITH increased kindling response; increased susceptibility to pharmacologically induced seizures; ASSOCIATED WITH Experimental Seizures; genetic disease (ortholog); Multiple Abnormalities (ortholog); FOUND IN dendrite; integral component of membrane; integral component of synaptic vesicle membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; acrylamide; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC105346; Sv2; synaptic vesicle glycoprotein 2 a; synaptic vesicle protein 2; synaptic vesicle protein 2A; synaptic vesicle transmembrane transporter (SV2) RNA
Orthologs:
Homo sapiens (human) : SV2A (synaptic vesicle glycoprotein 2A)  HGNC  Alliance
Mus musculus (house mouse) : Sv2a (synaptic vesicle glycoprotein 2 a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sv2a (synaptic vesicle glycoprotein 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : SV2A (synaptic vesicle glycoprotein 2A)
Canis lupus familiaris (dog) : SV2A (synaptic vesicle glycoprotein 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sv2a (synaptic vesicle glycoprotein 2A)
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Allele / Splice: Sv2am1Kyo  
Genetic Models: F344-Sv2am1Kyo
Is Marker For: Strains:   F344-Sv2am1Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02198,321,100 - 198,336,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02217,808,165 - 217,823,872 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,989,187 - 191,000,859 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,948,188 - 190,963,566 (+)NCBI
Celera2176,272,713 - 176,284,621 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sv2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619715
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-12-11
Status: ACTIVE