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Gene: Cacna1a (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit) Mus musculus
Symbol: Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Description: ENCODES a protein that exhibits high voltage-gated calcium channel activity; voltage-gated calcium channel activity; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels; INVOLVED IN adult walking behavior; behavioral response to pain; calcium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal action potential; abnormal axon morphology; abnormal brain interneuron morphology; ASSOCIATED WITH Ataxia; visual epilepsy; amyotrophic lateral sclerosis (ortholog); FOUND IN dendrite; glutamatergic synapse; neuronal cell body; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha1A; APCA; BI; brain calcium channel I; Caca1a; Cacnl1a4; calcium channel, L type, alpha-1 polypeptide; calcium channel, P/Q type, alpha 1A; Cav2.1; Ccha1a; EA2; FHM; HPCA; la; leaner; MHP; MHP1; nmf352; P/Q-type calcium channel alpha1A subunit; rkr; rocker; SCA6; smrl; tg; tottering; voltage-dependent P/Q-type calcium channel subunit alpha-1A; voltage-gated calcium channel subunit alpha Cav2.1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38884,338,631 - 84,640,251 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37886,939,263 - 87,164,148 (+)NCBIGRCm37mm9NCBIm37
MGSCv36887,305,469 - 87,530,351 (+)NCBImm8
Celera888,715,985 - 88,942,662 (+)NCBICelera
Cytogenetic Map8 C2NCBI
cM Map840.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cacna1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10265
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.