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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | affects expression | ISO | RGD:1317030 | 6480464 | 1, 2-Dimethylhydrazine affects the expression of KIFC3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1317030 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIFC3 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1317030 | 6480464 | Ethinyl Estradiol results in increased expression of KIFC3 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:1317029 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of KIFC3 mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | ISO | RGD:1317029 | 6480464 | Estradiol results in decreased expression of KIFC3 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | RGD:1317030 | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1317030 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIFC3 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KIFC3 mRNA | CTD | PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of KIFC3 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1317029 | 6480464 | Lactic Acid results in decreased expression of KIFC3 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1317030 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of KIFC3 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | increases methylation | ISO | RGD:1317030 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased methylation of KIFC3 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | RGD:1317030 | 6480464 | bis(4-hydroxyphenyl)sulfone affects the methylation of KIFC3 gene | CTD | PMID:31683443 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1317030 | 6480464 | Fenretinide results in increased expression of KIFC3 mRNA | CTD | PMID:28973697 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of KIFC3 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | RGD:1317029 | 6480464 | Acrylamide results in decreased expression of KIFC3 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of KIFC3 mRNA | CTD | PMID:25378103 | aflatoxin B1 | increases methylation | ISO | RGD:1317029 | 6480464 | Aflatoxin B1 results in increased methylation of KIFC3 intron, Aflatoxin B1 results in increased methylation of KIFC3 promoter | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | RGD:1317029 | 6480464 | aflatoxin B2 results in decreased methylation of KIFC3 intron | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of KIFC3 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of KIFC3 mRNA | CTD | PMID:30779732 | antirheumatic drug | decreases expression | ISO | RGD:1317029 | 6480464 | Antirheumatic Agents results in decreased expression of KIFC3 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | RGD:1317029 | 6480464 | Arsenic affects the methylation of KIFC3 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1317029 | 6480464 | Arsenic affects the methylation of KIFC3 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | RGD:1317030 | 6480464 | Benzo(a)pyrene results in decreased expression of KIFC3 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | RGD:1317029 | 6480464 | Benzo(a)pyrene results in increased methylation of KIFC3 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:1317029 | 6480464 | Benzo(a)pyrene affects the methylation of KIFC3 intron, Benzo(a)pyrene affects the methylation of KIFC3 promoter | CTD | PMID:27901495, PMID:30157460 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1317029 | 6480464 | 7 more ... | CTD | PMID:19150397 | Benzo[k]fluoranthene | decreases expression | ISO | RGD:1317030 | 6480464 | benzo(k)fluoranthene results in decreased expression of KIFC3 mRNA | CTD | PMID:26377693 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of KIFC3 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RGD:1317030 | 6480464 | bisphenol A results in increased expression of KIFC3 mRNA | CTD | PMID:32156529, PMID:34585602 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of KIFC3 mRNA | CTD | PMID:19167457 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of KIFC3 mRNA | CTD | PMID:19167457 | cadmium atom | decreases expression | ISO | RGD:1317029 | 6480464 | Cadmium results in decreased expression of KIFC3 mRNA | CTD | PMID:21297354 | caffeine | decreases phosphorylation | ISO | RGD:1317029 | 6480464 | Caffeine results in decreased phosphorylation of KIFC3 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | RGD:1317029 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KIFC3 gene] | CTD | PMID:28238834 | cisplatin | decreases expression | ISO | RGD:1317029 | 6480464 | Cisplatin results in decreased expression of KIFC3 mRNA | CTD | PMID:27392435 | clothianidin | increases expression | ISO | RGD:1317029 | 6480464 | clothianidin results in increased expression of KIFC3 mRNA | CTD | PMID:31626844 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of KIFC3 mRNA | CTD | PMID:24386269 | cyclosporin A | increases expression | ISO | RGD:1317029 | 6480464 | Cyclosporine results in increased expression of KIFC3 mRNA | CTD | PMID:25562108 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of KIFC3 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | RGD:1317029 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC3 mRNA | CTD | PMID:27188386 | ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of KIFC3 mRNA | CTD | PMID:17347304 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of KIFC3 mRNA | CTD | PMID:25539665, PMID:26194646 | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of KIFC3 gene | CTD | PMID:28505145 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of KIFC3 mRNA | CTD | PMID:33387578 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of KIFC3 mRNA | CTD | PMID:21396975 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of KIFC3 mRNA | CTD | PMID:22129741 | inulin | multiple interactions | ISO | RGD:1317030 | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of KIFC3 mRNA | CTD | PMID:36331819 | methylphenidate | decreases expression | ISO | RGD:1317030 | 6480464 | Methylphenidate results in decreased expression of KIFC3 mRNA | CTD | PMID:22470460 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of KIFC3 mRNA | CTD | PMID:22129741 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of KIFC3 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | RGD:1317030 | 6480464 | Acetaminophen affects the expression of KIFC3 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KIFC3 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:1317030 | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of KIFC3 mRNA | CTD | PMID:36331819 | phenylmercury acetate | increases expression | ISO | RGD:1317029 | 6480464 | Phenylmercuric Acetate results in increased expression of KIFC3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1317029 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC3 mRNA | CTD | PMID:27188386 | rac-lactic acid | decreases expression | ISO | RGD:1317029 | 6480464 | Lactic Acid results in decreased expression of KIFC3 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | RGD:1317029 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIFC3 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | RGD:1317029 | 6480464 | sodium arsenite results in increased expression of KIFC3 mRNA | CTD | PMID:29301061 | succimer | multiple interactions | ISO | RGD:1317030 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of KIFC3 mRNA | CTD | PMID:21641980 | sunitinib | decreases expression | ISO | RGD:1317029 | 6480464 | Sunitinib results in decreased expression of KIFC3 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of KIFC3 mRNA | CTD | PMID:23411599 | titanium dioxide | decreases methylation | ISO | RGD:1317029 | 6480464 | titanium dioxide results in decreased methylation of KIFC3 promoter | CTD | PMID:34973136 | triclosan | increases expression | ISO | RGD:1317029 | 6480464 | Triclosan results in increased expression of KIFC3 mRNA | CTD | PMID:30510588 | Triptolide | increases expression | ISO | RGD:1317030 | 6480464 | triptolide results in increased expression of KIFC3 mRNA | CTD | PMID:32835833 | triptonide | decreases expression | ISO | RGD:1317030 | 6480464 | triptonide results in decreased expression of KIFC3 mRNA | CTD | PMID:33045310 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of KIFC3 mRNA | CTD | PMID:23034163 | |