 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | MGD data from the GO Consortium |
| 3. | Pipeline to import KEGG annotations from KEGG into RGD |
| 4. | RGD automated data pipeline |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Mri1 (Rattus norvegicus - Norway rat) |
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| MRI1 (Homo sapiens - human) |
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| Mri1 (Mus musculus - house mouse) |
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| Mri1 (Chinchilla lanigera - long-tailed chinchilla) |
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| MRI1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MRI1 (Canis lupus familiaris - dog) |
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| Mri1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MRI1 (Sus scrofa - pig) |
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| MRI1 (Chlorocebus sabaeus - African green monkey) |
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| Mri1 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| RH126162 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 20 | 30 | 24 | 5 | 24 | 2 | 72 | 32 | 33 | 3 | ||
| Low | 23 | 27 | 17 | 14 | 17 | 8 | 9 | 2 | 3 | 8 | 8 | 8 | |
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001010947 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07043172 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01097732 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC089060 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473972 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ213644 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000003762 ⟹ ENSRNOP00000003762 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001010947 ⟹ NP_001010947 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
CGCAACCTGTGCGGGATTCTGTGTGGCCCTGTACGGTAGGCAACATGAGACTGGAAGCGATCCGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001010947 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAH89060 | (Get FASTA) | NCBI Sequence Viewer |
| EDL92227 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL92228 | (Get FASTA) | NCBI Sequence Viewer | |
| Q5HZE4 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001010947 ⟸ NM_001010947 |
| - UniProtKB: | Q5HZE4 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MRLEAIRYSPGSLQILDQLQLPEHCHYETLSSVQQAREAIRAMKVRGAPAIALVGCLSLAVELQhide sequence |
| RefSeq Acc Id: | ENSRNOP00000003762 ⟸ ENSRNOT00000003762 |
TranscriptomePromoters| RGD ID: | 13701017 | ||||||||
| Promoter ID: | EPDNEW_R11541 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Mri1_1 | ||||||||
| Description: | methylthioribose-1-phosphate isomerase 1 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1307789 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000026211 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000003762 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000003762 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Gene3D-CATH | 1.20.120.420 | UniProtKB/Swiss-Prot |
| 3.40.50.10470 | UniProtKB/Swiss-Prot | |
| IMAGE_CLONE | IMAGE:7320396 | IMAGE-MGC_LOAD |
| InterPro | IF-2B-related | UniProtKB/Swiss-Prot |
| IF-M1Pi | UniProtKB/Swiss-Prot | |
| IF_2B-like_C | UniProtKB/Swiss-Prot | |
| Initiation_fac_2B_a/b/d | UniProtKB/Swiss-Prot | |
| M1Pi_N | UniProtKB/Swiss-Prot | |
| NagB/RpiA_transferase-like | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:288912 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:105780 | IMAGE-MGC_LOAD |
| NCBI Gene | 288912 | ENTREZGENE |
| Pfam | IF-2B | UniProtKB/Swiss-Prot |
| PhenoGen | Mri1 | PhenoGen |
| Superfamily-SCOP | SSF100950 | UniProtKB/Swiss-Prot |
| TIGRFAMs | eIF-2B_rel | UniProtKB/Swiss-Prot |
| salvage_mtnA | UniProtKB/Swiss-Prot | |
| UniGene | Rn.16390 | ENTREZGENE |
| UniProt | MTNA_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2013-06-05 | Mri1 | methylthioribose-1-phosphate isomerase 1 | Mri1 | methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2009-06-12 | Mri1 | methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) | RGD1307789 | translation initiation factor eIF-2B subunit alpha/beta/delta-like protein | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2009-01-20 | RGD1307789 | translation initiation factor eIF-2B subunit alpha/beta/delta-like protein | RGD1307789 | similar to hypothetical protein MGC3207 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-12-06 | RGD1307789 | similar to hypothetical protein MGC3207 | RGD1307789_predicted | similar to hypothetical protein MGC3207 (predicted) | Symbol and Name updated | 1559027 | APPROVED |
| 2005-01-20 | RGD1307789_predicted | similar to hypothetical protein MGC3207 (predicted) | LOC288912_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
| 2005-01-12 | LOC288912_predicted | similar to hypothetical protein MGC3207 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Mri1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1307789 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
