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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1552286 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT21 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1552286 | 6480464 | Ethinyl Estradiol affects the expression of NUDT21 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1552286 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1552286 | 6480464 | Ethinyl Estradiol results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | RGD:1552286 | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1552286 | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT21 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT21 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1552286 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUDT21 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1552286 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT21 mRNA | CTD | PMID:26290441 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1313996 | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT21 mRNA | CTD | PMID:22574217 | 2,4,6-tribromophenol | decreases expression | ISO | RGD:1313996 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1313996 | 6480464 | Lactic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1313996 | 6480464 | tetrabromobisphenol A results in decreased expression of NUDT21 protein | CTD | PMID:31675489 | 3-methylcholanthrene | increases expression | ISO | RGD:1552286 | 6480464 | Methylcholanthrene results in increased expression of NUDT21 mRNA | CTD | PMID:20713471 | all-trans-retinoic acid | decreases expression | ISO | RGD:1313996 | 6480464 | Tretinoin results in decreased expression of NUDT21 mRNA | CTD | PMID:15498508, PMID:33167477 | aristolochic acid | decreases expression | ISO | RGD:1313996 | 6480464 | aristolochic acid I results in decreased expression of NUDT21 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | RGD:1313996 | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to NUDT21 protein], arsenite promotes the reaction [G3BP1 protein binds to NUDT21 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | RGD:1552286 | 6480464 | Benzo(a)pyrene results in increased expression of NUDT21 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | RGD:1313996 | 6480464 | Benzo(a)pyrene results in decreased expression of NUDT21 mRNA | CTD | PMID:21632981 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1313996 | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NUDT21 mRNA | CTD | PMID:25181051 | bisphenol A | affects expression | ISO | RGD:1313996 | 6480464 | bisphenol A affects the expression of NUDT21 mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NUDT21 mRNA | CTD | PMID:30816183 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of NUDT21 protein | CTD | PMID:28903499 | carbon nanotube | increases expression | ISO | RGD:1552286 | 6480464 | Nanotubes, Carbon results in increased expression of NUDT21 mRNA | CTD | PMID:25554681 | cisplatin | increases expression | ISO | RGD:1313996 | 6480464 | Cisplatin results in increased expression of NUDT21 mRNA | CTD | PMID:27594783 | copper atom | multiple interactions | ISO | RGD:1313996 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NUDT21 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | RGD:1313996 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of NUDT21 mRNA | CTD | PMID:20971185 | coumestrol | increases expression | ISO | RGD:1313996 | 6480464 | Coumestrol results in increased expression of NUDT21 mRNA | CTD | PMID:19167446 | cyclosporin A | decreases expression | ISO | RGD:1552286 | 6480464 | Cyclosporine results in decreased expression of NUDT21 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | RGD:1313996 | 6480464 | Cyclosporine results in decreased expression of NUDT21 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | increases expression | ISO | RGD:1313996 | 6480464 | decabromobiphenyl ether results in increased expression of NUDT21 protein | CTD | PMID:31675489 | dexamethasone | increases expression | ISO | RGD:1552286 | 6480464 | Dexamethasone results in increased expression of NUDT21 mRNA | CTD | PMID:17998272 | dorsomorphin | multiple interactions | ISO | RGD:1313996 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT21 mRNA | CTD | PMID:27188386 | ethanol | affects expression | ISO | RGD:1552286 | 6480464 | Ethanol affects the expression of NUDT21 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | RGD:1552286 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT21 mRNA | CTD | PMID:22206623 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of NUDT21 mRNA | CTD | PMID:22061828 | isotretinoin | decreases expression | ISO | RGD:1313996 | 6480464 | Isotretinoin results in decreased expression of NUDT21 mRNA | CTD | PMID:20436886 | ivermectin | decreases expression | ISO | RGD:1313996 | 6480464 | Ivermectin results in decreased expression of NUDT21 protein | CTD | PMID:32959892 | methidathion | affects expression | ISO | RGD:1552286 | 6480464 | methidathion affects the expression of NUDT21 mRNA | CTD | PMID:34813904 | methotrexate | affects expression | ISO | RGD:1552286 | 6480464 | Methotrexate affects the expression of NUDT21 mRNA | CTD | PMID:18502557 | methylmercury chloride | increases expression | ISO | RGD:1313996 | 6480464 | methylmercuric chloride results in increased expression of NUDT21 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:1313996 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of NUDT21 protein | CTD | PMID:24806433 | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of NUDT21 mRNA | CTD | PMID:22124623 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NUDT21 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | RGD:1552286 | 6480464 | Acetaminophen affects the expression of NUDT21 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | RGD:1313996 | 6480464 | Acetaminophen results in decreased expression of NUDT21 mRNA | CTD | PMID:21420995, PMID:26497421 | pirinixic acid | increases expression | ISO | RGD:1552286 | 6480464 | pirinixic acid results in increased expression of NUDT21 mRNA | CTD | PMID:23811191 | piroxicam | decreases expression | ISO | RGD:1313996 | 6480464 | Piroxicam results in decreased expression of NUDT21 mRNA | CTD | PMID:21858171 | rac-lactic acid | decreases expression | ISO | RGD:1313996 | 6480464 | Lactic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:1313996 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of NUDT21 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | RGD:1313996 | 6480464 | Rotenone results in increased expression of NUDT21 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | RGD:1313996 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT21 mRNA | CTD | PMID:27188386 | sodium arsenite | increases activity | ISO | RGD:1313996 | 6480464 | sodium arsenite results in increased activity of NUDT21 protein | CTD | PMID:30528433 | tamibarotene | affects expression | ISO | RGD:1313996 | 6480464 | tamibarotene affects the expression of NUDT21 mRNA | CTD | PMID:15498508 | tamoxifen | affects expression | ISO | RGD:1552286 | 6480464 | Tamoxifen affects the expression of NUDT21 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:1313996 | 6480464 | tert-Butylhydroperoxide results in decreased expression of NUDT21 mRNA | CTD | PMID:15336504 | tert-butyl hydroperoxide | increases expression | ISO | RGD:1313996 | 6480464 | tert-Butylhydroperoxide results in increased expression of NUDT21 mRNA | CTD | PMID:15336504 | thapsigargin | decreases expression | ISO | RGD:1552286 | 6480464 | Thapsigargin results in decreased expression of NUDT21 protein | CTD | PMID:24648495 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NUDT21 mRNA | CTD | PMID:25729387 | trichostatin A | multiple interactions | ISO | RGD:1313996 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT21 mRNA | CTD | PMID:27188386 | trimellitic anhydride | increases expression | ISO | RGD:1552286 | 6480464 | trimellitic anhydride results in increased expression of NUDT21 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | RGD:1313996 | 6480464 | troglitazone results in decreased expression of NUDT21 mRNA | CTD | PMID:19140230 | troglitazone | decreases expression | ISO | RGD:1552286 | 6480464 | troglitazone results in decreased expression of NUDT21 mRNA | CTD | PMID:28973697 | tungsten | increases expression | ISO | RGD:1552286 | 6480464 | Tungsten results in increased expression of NUDT21 mRNA | CTD | PMID:30912803 | valproic acid | decreases methylation | ISO | RGD:1313996 | 6480464 | Valproic Acid results in decreased methylation of NUDT21 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1313996 | 6480464 | Valproic Acid results in increased expression of NUDT21 mRNA, Valproic Acid results in increased expression of NUDT21 protein | CTD | PMID:29501571 | valproic acid | increases methylation | ISO | RGD:1313996 | 6480464 | Valproic Acid results in increased methylation of NUDT21 gene | CTD | PMID:29501571 | valproic acid | affects expression | ISO | RGD:1313996 | 6480464 | Valproic Acid affects the expression of NUDT21 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | RGD:1313996 | 6480464 | Valproic Acid results in decreased expression of NUDT21 mRNA | CTD | PMID:23179753 | vancomycin | decreases expression | ISO | RGD:1552286 | 6480464 | Vancomycin results in decreased expression of NUDT21 mRNA | CTD | PMID:18930951 | |