Rps27a-ps6 (ribosomal protein S27a, pseudogene 6) - Rat Genome Database

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Gene: Rps27a-ps6 (ribosomal protein S27a, pseudogene 6) Rattus norvegicus
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Symbol: Rps27a-ps6
Name: ribosomal protein S27a, pseudogene 6
RGD ID: 1588826
Description: Predicted to be involved in translation. Predicted to be located in nucleus. Orthologous to human RPS27AP5 (ribosomal protein S27a pseudogene 5); INTERACTS WITH Cuprizon.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: AABR07043659.1; LOC688462; ribosomal protein S27a-like; similar to ribosomal protein S27a
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Related Functional Gene: Rps27a  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81947,820,487 - 47,821,041 (+)NCBIGRCr8
mRatBN7.21930,916,279 - 30,916,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1930,916,304 - 30,916,801 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1937,754,981 - 37,755,535 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01938,408,839 - 38,409,393 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.01934,616,743 - 34,617,297 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1934,616,768 - 34,617,265 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01945,494,945 - 45,495,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,728,761 - 32,729,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1930,391,694 - 30,392,248 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Cuprizon  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Rps27a-ps6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81947,820,487 - 47,821,041 (+)NCBIGRCr8
mRatBN7.21930,916,279 - 30,916,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1930,916,304 - 30,916,801 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1937,754,981 - 37,755,535 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01938,408,839 - 38,409,393 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.01934,616,743 - 34,617,297 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1934,616,768 - 34,617,265 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01945,494,945 - 45,495,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41932,728,761 - 32,729,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1930,391,694 - 30,392,248 (+)NCBICelera
Cytogenetic Map19q11NCBI
RPS27AP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381192,716,135 - 192,716,683 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1192,716,183 - 192,716,653 (+)EnsemblGRCh38hg38GRCh38
GRCh371192,685,265 - 192,685,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361192,685,267 - 192,685,813 (+)NCBINCBI36Build 36hg18NCBI36
Celera1165,794,987 - 165,795,533 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1163,921,206 - 163,921,752 (+)NCBIHuRef
CHM1_11194,107,035 - 194,107,581 (+)NCBICHM1_1
T2T-CHM13v2.01192,063,215 - 192,063,763 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in Rps27a-ps6
7 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192481604133061905Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat

Markers in Region
PMC280674P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q22UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000051194   ⟹   ENSRNOP00000047281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1930,916,304 - 30,916,801 (+)Ensembl
RefSeq Acc Id: XM_001066030   ⟹   XP_001066030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_5.01945,494,945 - 45,495,486 (+)NCBI
RGSC_v3.41932,728,761 - 32,729,228 (+)RGD
RefSeq Acc Id: XM_003753098   ⟹   XP_003753146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1930,391,730 - 30,392,271 (+)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000047281.5
RefSeq Acc Id: XP_001066030   ⟸   XM_001066030
- Sequence:
RefSeq Acc Id: XP_003753146   ⟸   XM_003753098
- Sequence:
Ensembl Acc Id: ENSRNOP00000047281   ⟸   ENSRNOT00000051194
Protein Domains
Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A0J6-F1-model_v2 AlphaFold D4A0J6 1-165 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588826 AgrOrtholog
BioCyc Gene G2FUF-5898 BioCyc
Ensembl Genes ENSRNOG00000029317 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051194.6 UniProtKB/TrEMBL
Gene3D-CATH 6.20.50.150 UniProtKB/TrEMBL
InterPro Ribosomal_S27a UniProtKB/TrEMBL
  Ribosomal_zn-bd UniProtKB/TrEMBL
  S27a-like_sf UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  Ubiquitin_CS UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/TrEMBL
  Ubiquitin_ubiquitin-like UniProtKB/TrEMBL
NCBI Gene 688462 ENTREZGENE
PANTHER UBIQUITIN UniProtKB/TrEMBL
  UBIQUITIN-60S RIBOSOMAL PROTEIN L40 UniProtKB/TrEMBL
Pfam Ribosomal_S27 UniProtKB/TrEMBL
  ubiquitin UniProtKB/TrEMBL
PhenoGen Rps27a-ps6 PhenoGen
PRINTS UBIQUITIN UniProtKB/TrEMBL
PROSITE UBIQUITIN_1 UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029317 RatGTEx
SMART Ribosomal_S27 UniProtKB/TrEMBL
  UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF57829 UniProtKB/TrEMBL
UniProt D4A0J6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Rps27a-ps6  ribosomal protein S27a, pseudogene 6  AABR07043659.1    Data merged from RGD:15003743 737654 PROVISIONAL
2019-11-08 AABR07043659.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2015-05-18 Rps27a-ps6  ribosomal protein S27a, pseudogene 6  LOC688462  similar to ribosomal protein S27a  Name and Symbol changed 629549 APPROVED
2013-05-24 LOC688462  similar to ribosomal protein S27a  LOC100363614  ribosomal protein S27a-like  Data merged from RGD:2322635 1643240 APPROVED
2010-05-06 LOC100363614  ribosomal protein S27a-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC688462  similar to ribosomal protein S27a  LOC684772  similar to ribosomal protein S27a  Data merged from RGD:1586723 1643240 APPROVED
2006-11-19 LOC688462  similar to ribosomal protein S27a      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684772  similar to ribosomal protein S27a      Symbol and Name status set to provisional 70820 PROVISIONAL